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Rare rapid progression of intra-ampullary papillary-tubular neoplasm with low-grade dysplasia
Rare rapid progression of intra-ampullary papillary-tubular neoplasm with low-grade dysplasia
A 78-year-old woman presented with epigastric pain and underwent contrast-enhanced abdominal computed tomography (CT), whi...
Gastric adenocarcinoma with submucosal invasion occurs in a sporadic fundic gland polyp of a -uninfected patient on proton pump inhibitor
Gastric adenocarcinoma with submucosal invasion occurs in a sporadic fundic gland polyp of a -uninfected patient on proton pump inhibitor
Gastric fundic gland polyps (FGPs) are common benign lesions, typically found in Helicobacter pylori (HP)-uninfected stoma...
A case of distal bile duct cancer in a patient with polysplenia syndrome and ventral pancreatic malrotation
A case of distal bile duct cancer in a patient with polysplenia syndrome and ventral pancreatic malrotation
Polysplenia syndrome is a rare congenital anomaly characterized by visceral malposition associated with multiple spleens. ...
A case of extensive intraepithelial lesions throughout the pancreas with focal high-grade pancreatic intraepithelial neoplasm: implications for diagnosis and surgical strategy
A case of extensive intraepithelial lesions throughout the pancreas with focal high-grade pancreatic intraepithelial neoplasm: implications for diagnosis and surgical strategy
In the preoperative pathological diagnosis of high-grade pancreatic intraepithelial neoplasia (PanIN), pancreatic juice cy...
Successful conversion surgery for patients with pancreatic cancer, positive peritoneal cytology, and liver metastasis who were treated with chemotherapy involving nanoliposomal irinotecan with fluorouracil and folinic acid
Successful conversion surgery for patients with pancreatic cancer, positive peritoneal cytology, and liver metastasis who were treated with chemotherapy involving nanoliposomal irinotecan with fluorouracil and folinic acid
A 67-year-old woman was diagnosed with pancreatic head cancer. Staging laparoscopy (SL) was performed, peritoneal cytology...
First report of metabolic complete response in hepatic sarcomatoid carcinoma achieved with carbon-ion radiotherapy
First report of metabolic complete response in hepatic sarcomatoid carcinoma achieved with carbon-ion radiotherapy
Hepatic sarcomatoid carcinoma (HSC) is a rare and highly aggressive subtype of primary liver cancer with no established tr...
Immune-related adverse events in patients with low baseline serum IL-6 treated with durvalumab plus tremelimumab for hepatocellular carcinoma: a case series
Immune-related adverse events in patients with low baseline serum IL-6 treated with durvalumab plus tremelimumab for hepatocellular carcinoma: a case series
Systemic therapy for advanced hepatocellular carcinoma (HCC) has progressed significantly, yet the management of immune-re...
Severe luminal stricture in immune-related adverse event-associated enteritis: a case report
Severe luminal stricture in immune-related adverse event-associated enteritis: a case report
Immune checkpoint inhibitors, such as ipilimumab and nivolumab, target cytotoxic T-lymphocyte-associated antigen 4 and pro...
Two duodenal sessile serrated lesions in a patient with serrated polyposis syndrome: case report and review of the literature
Two duodenal sessile serrated lesions in a patient with serrated polyposis syndrome: case report and review of the literature
The serrated neoplastic pathway has been reported to be involved in the development of colorectal cancer, and serrated les...
Endoscopic closure of 5-cm long esophageal perforation in an elderly patient with achalasia
Endoscopic closure of 5-cm long esophageal perforation in an elderly patient with achalasia
Chronic esophageal achalasia can lead to significant morphological changes in the esophagus, posing challenges during endo...
Sclerosing angiomatoid nodular transformation of the spleen with thrombocytopenia
Sclerosing angiomatoid nodular transformation of the spleen with thrombocytopenia
Sclerosing angiomatoid nodular transformation (SANT) is a rare benign vascular disease of the spleen. We report the case o...
Successful endoscopic removal of an impacted esophageal sponge in an elderly woman with dementia
Successful endoscopic removal of an impacted esophageal sponge in an elderly woman with dementia
An 81-year-old woman residing in a nursing facility due to dementia presented with a 5-day history of vomiting and anorexi...
Hepatic angiosarcoma presenting with clinical features of decompensated cirrhosis
Hepatic angiosarcoma presenting with clinical features of decompensated cirrhosis
Hepatic angiosarcoma (HAS) is a rare, highly aggressive vascular malignancy. HAS presents with nonspecific clinical and im...
Chronic lymphocytic leukemia complicated by non-cirrhotic portal hypertension: an autopsy case report
Chronic lymphocytic leukemia complicated by non-cirrhotic portal hypertension: an autopsy case report
Portal hypertension typically occurs in cirrhosis but can rarely develop in the absence of hepatic fibrosis, particularly ...
Histopathological changes in two patients with hypertriglyceridemia and metabolic dysfunction-associated steatotic liver disease treated with pemafibrate: a serial liver biopsy study
Histopathological changes in two patients with hypertriglyceridemia and metabolic dysfunction-associated steatotic liver disease treated with pemafibrate: a serial liver biopsy study
This study investigated histological liver-tissue changes before and after 1 year of pemafibrate treatment in two...
Hepatic focal nodular hyperplasia after liver transplantation: case report and review of literature
Hepatic focal nodular hyperplasia after liver transplantation: case report and review of literature
Patients with decompensated cirrhosis complicated by hepatocellular carcinoma (HCC) or those who have undergone liver tran...
Percutaneous endoscopic necrosectomy for extensive walled-off necrosis using two endoscopes simultaneously: a report of two cases
Percutaneous endoscopic necrosectomy for extensive walled-off necrosis using two endoscopes simultaneously: a report of two cases
Endoscopic step-up approach, which involves endoscopic ultrasound-guided drainage followed by necrosectomy, has been sugge...
Hepatocellular carcinoma with recurrent pancreatic metastasis 17 years after radical resection
Hepatocellular carcinoma with recurrent pancreatic metastasis 17 years after radical resection
Hepatocellular carcinoma (HCC) has a high recurrence rate, typically within 2 years after surgical radical resect...
A case of gallbladder metastases with a different histologic type detected during lung cancer treatment
A case of gallbladder metastases with a different histologic type detected during lung cancer treatment
A 47-year-old man undergoing follow-up for previously treated squamous cell carcinoma of the lung was found to have two ma...
A case of complete remission by cabozantinib as an end-line treatment for advanced hepatocellular carcinoma
A case of complete remission by cabozantinib as an end-line treatment for advanced hepatocellular carcinoma
Cabozantinib is a multi-kinase inhibitor targeting multiple tyrosine kinases. It improves overall survival and progression...
Successful radical surgery for lymph node metastasis in a patient with hepatocellular carcinoma following atezolizumab plus bevacizumab combination therapy: a case report and literature review
Successful radical surgery for lymph node metastasis in a patient with hepatocellular carcinoma following atezolizumab plus bevacizumab combination therapy: a case report and literature review
A woman in her early 80 s was followed up in our hospital for chronic hepatitis C after viral eradication. We detected rap...
Successful novel use of dupilumab for gastrointestinal involvement of idiopathic hypereosinophilic syndrome: case report and review of the literature
Successful novel use of dupilumab for gastrointestinal involvement of idiopathic hypereosinophilic syndrome: case report and review of the literature
Hypereosinophilic syndrome (HES) is characterized by blood and tissue hypereosinophilia leading to organ damage. Gastroint...
A small bowel adenocarcinoma harboring a DDR2 mutation in a celiac patient
A small bowel adenocarcinoma harboring a DDR2 mutation in a celiac patient
We present the case of a 62-year-old man with a history of celiac disease and IgA deficiency, following a strict gluten-fr...
A case of colon cancer implanted on endoscopic resection ulcer certified by cancer genomic testing
A case of colon cancer implanted on endoscopic resection ulcer certified by cancer genomic testing
A 90 year-old man underwent endoscopic mucosal resection for lesions in the descending and sigmoid colons as well...
Portal vein stenting blocked the inflow tract and completely resolved bile duct varices, formed by cavernous transformation of the portal vein
Portal vein stenting blocked the inflow tract and completely resolved bile duct varices, formed by cavernous transformation of the portal vein
There is no established treatment for bleeding bile duct varices (BDVs). We report the first case of portal vein (PV) sten...
Tubular adenoma at the hepatico-jejunal anastomosis in familial adenomatous polyposis (FAP) following pancreaticoduodenectomy: challenges in adenoma surveillance and management
Tubular adenoma at the hepatico-jejunal anastomosis in familial adenomatous polyposis (FAP) following pancreaticoduodenectomy: challenges in adenoma surveillance and management
Upper gastrointestinal tumors, including ampullary adenomas, occur frequently in patients with familial adenomatous polypo...
Endoscopic ultrasound-guided fine-needle biopsy diagnosing pancreatic metastasis seven years after renal leiomyosarcoma resection: a case report
Endoscopic ultrasound-guided fine-needle biopsy diagnosing pancreatic metastasis seven years after renal leiomyosarcoma resection: a case report
Renal leiomyosarcoma metastasis to the pancreas is exceptionally rare. Here, we present a case of metastatic recurrence in...
A case of immune checkpoint inhibitor-associated hemophagocytosis after initiation of atezolizumab plus bevacizumab therapy for advanced hepatocellular carcinoma
A case of immune checkpoint inhibitor-associated hemophagocytosis after initiation of atezolizumab plus bevacizumab therapy for advanced hepatocellular carcinoma
A woman in the 70s with a decreased appetite and weight loss (4 kg) in the last 3 months was referred to...
Endoscopic ultrasound-guided drainage for mediastinal abscess: first report of bridge to surgery for esophageal cancer
Endoscopic ultrasound-guided drainage for mediastinal abscess: first report of bridge to surgery for esophageal cancer
Perforated esophageal cancer rarely results in the formation of mediastinal abscess. Endoscopic ultrasound (EUS)-guided ab...
Variceal bleeding following treatment with atezolizumab plus bevacizumab in two patients with unresectable hepatocellular carcinoma
Variceal bleeding following treatment with atezolizumab plus bevacizumab in two patients with unresectable hepatocellular carcinoma
Bleeding-related adverse events may occur due to anti-vascular endothelial growth factors. Here, we report two cases of va...
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