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Deciphering Cancer Evolution Through Genomic Profiling of Patient-Derived Xenograft Together with Matched Primary Gallbladder Cancer
Deciphering Cancer Evolution Through Genomic Profiling of Patient-Derived Xenograft Together with Matched Primary Gallbladder Cancer
Gallbladder cancer has a poor prognosis due to its aggressive nature and late detection. Adenosquamous subtypes are rare a...
Fistula Outcomes After Seton Removal in Patients with Perianal Fistulizing Crohn’s Disease: A Systematic Review and Meta-Analysis
Fistula Outcomes After Seton Removal in Patients with Perianal Fistulizing Crohn’s Disease: A Systematic Review and Meta-Analysis
While setons are commonly used in the multidisciplinary care of patients with perianal fistulizing Crohn’s disease (...
A Sewing Needle in the Sigmoid Colon
A Sewing Needle in the Sigmoid Colon
Conflict of interest The authors declare no competing interests. ...
Adenomyomatous Hyperplasia of the Ampulla of Vater: Diagnostic Snapshot of a Benign Mimicker of Malignancy
Adenomyomatous Hyperplasia of the Ampulla of Vater: Diagnostic Snapshot of a Benign Mimicker of Malignancy
Cite this articleWadekar, A., Maurya, S., Dutta, R. et al. Adenomyomatous Hyperplasia of the Ampulla of Vater: Diagnostic ...
Outcomes of Hospitalized Patients with Severe UC from 1997 to 2021 in a Large Regional Healthcare System in the US
Outcomes of Hospitalized Patients with Severe UC from 1997 to 2021 in a Large Regional Healthcare System in the US
Disease course following hospitalization for severe ulcerative colitis (UC) is poorly understood. Here, we evaluate the ou...
Systematic Review of Bile Acids Metabolism in Crohn’s Disease: Implications for Pathogenesis and Therapeutic Interventions
Systematic Review of Bile Acids Metabolism in Crohn’s Disease: Implications for Pathogenesis and Therapeutic Interventions
Crohn’s disease (CD) is a chronic inflammatory bowel disorder characterized by transmural inflammation of the gastro...
AI-Based Models for Risk Prediction in MASLD: A Systematic Review
AI-Based Models for Risk Prediction in MASLD: A Systematic Review
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a rapidly growing global health concern. This systemat...
S100A6 Regulated by PATZ1 Promotes Liver Fibrosis by Activating Hepatic Stellate Cells
S100A6 Regulated by PATZ1 Promotes Liver Fibrosis by Activating Hepatic Stellate Cells
The transition of hepatic stellate cells (HSCs) from a quiescent state to active myofibroblasts plays a pivotal role in th...
Colorectal Cancer Screening and Mortality Trends in the United States Over 25 Years: A Story of Success and Inequity 
Colorectal Cancer Screening and Mortality Trends in the United States Over 25 Years: A Story of Success and Inequity 
Colorectal cancer (CRC) is the fourth most common cancer in the USA and second leading cause of cancer deaths. While scree...
Use of Sodium Butyrate and Its Microencapsulated Forms in Intestinal Diseases—Current Clinical Approach
Use of Sodium Butyrate and Its Microencapsulated Forms in Intestinal Diseases—Current Clinical Approach
 In recent years, the importance of butyrate in prevention and health promotion in human health has been revealed...
Learning Curve of Endoscopic Submucosal Dissection for Early Esophageal Cancer Among Endoscopists with Varying Experience
Learning Curve of Endoscopic Submucosal Dissection for Early Esophageal Cancer Among Endoscopists with Varying Experience
Esophageal endoscopic submucosal dissection (E-ESD) is a key treatment modality for early-stage esophageal cancer. However...
Endoscopic Treatment for Crohn’s Disease-Related Deep Small Intestinal Strictures: Balloon-Assisted Enteroscopy-Guided Stricturotomy Versus Balloon Dilation Therapy—A Single-Center Retrospective Study
Endoscopic Treatment for Crohn’s Disease-Related Deep Small Intestinal Strictures: Balloon-Assisted Enteroscopy-Guided Stricturotomy Versus Balloon Dilation Therapy—A Single-Center Retrospective Study
Research data on balloon-assisted enteroscopy-guided stricturotomy (BAE-ES) versus endoscopic balloon dilation (BAE-EBD) f...
Cecal Volvulus Mimicking Small Bowel Obstruction—A Diagnostic Dilemma
Cecal Volvulus Mimicking Small Bowel Obstruction—A Diagnostic Dilemma
Conflict of interest The authors declare no competing interests. ...
Exploring Transcriptomic and MRI-Derived Parameters Correlations in NAFLD Fibrosis: Insights from a Rat Model
Exploring Transcriptomic and MRI-Derived Parameters Correlations in NAFLD Fibrosis: Insights from a Rat Model
Nonalcoholic fatty liver disease (NAFLD), which affects approximately 25% of the adult population, represents a significan...
Geographic Disparities in the Supply and Demand of Gastroenterologists Across the United States: Forecasting a National Shortage
Geographic Disparities in the Supply and Demand of Gastroenterologists Across the United States: Forecasting a National Shortage
There is a lack of contemporary research on the supply and demand of gastroenterologists in the United States (US). We hyp...
Pseudoaneurysms Post-biliary Stenting: A Comprehensive Literature Review
Pseudoaneurysms Post-biliary Stenting: A Comprehensive Literature Review
Pseudoaneurysms (PSA) following endoscopic biliary stenting are a rare, potentially life-threatening adverse event. Incide...
Per-oral Pancreatoscopy-Guided Lithotripsy Versus Extracorporeal Shock Wave Lithotripsy in Pancreatic Stone: A Meta-Analysis
Per-oral Pancreatoscopy-Guided Lithotripsy Versus Extracorporeal Shock Wave Lithotripsy in Pancreatic Stone: A Meta-Analysis
Pancreatic duct stones (PDS) pose a significant clinical challenge, and choosing treatment modality is crucial to achievin...
Using Machine Learning Methods to Develop Diagnostic and Prognostic mRNA Signatures for Pancreatic Cancer in Plasma Small Extracellular Vesicles
Using Machine Learning Methods to Develop Diagnostic and Prognostic mRNA Signatures for Pancreatic Cancer in Plasma Small Extracellular Vesicles
Pancreatic ductal adenocarcinoma (PDAC) is frequently diagnosed in advanced stage due to the absence of effective diagnost...
Will Rogers Paradox in Gastroenterology
Will Rogers Paradox in Gastroenterology
The use of various classifications to grade and differentiate appearances of digestive diseases has enhanced precision and...
Bone Broth Benefits: How Its Nutrients Fortify Gut Barrier in Health and Disease
Bone Broth Benefits: How Its Nutrients Fortify Gut Barrier in Health and Disease
Bone broth is a traditional nutrient revered by different people from ancient times to the modern era as a remedy for vari...
Long-Term Outcomes of Carvedilol Plus Endoscopic Variceal Ligation in Secondary Prophylaxis of Variceal Bleeding
Long-Term Outcomes of Carvedilol Plus Endoscopic Variceal Ligation in Secondary Prophylaxis of Variceal Bleeding
Carvedilol is key for primary prophylaxis of high-risk variceal bleeding but is less studied for secondary prophylaxis wit...
Advancing Upper Gastrointestinal Cancer Detection: A Single-Center Pilot Study Exploring the Potential of Electrical Impedance Spectroscopy in Endoscopic Procedures
Advancing Upper Gastrointestinal Cancer Detection: A Single-Center Pilot Study Exploring the Potential of Electrical Impedance Spectroscopy in Endoscopic Procedures
Early detection of GI cancer mass is of utmost importance due to the risks of misdiagnoses that occur through standard end...
Evaluation of Acute Severe Ulcerative Colitis Predictors for Steroid Therapy Refractoriness
Evaluation of Acute Severe Ulcerative Colitis Predictors for Steroid Therapy Refractoriness
One-third of patients presenting with acute severe ulcerative colitis (ASUC) are steroid-refractory and require either col...
Hidden Fecalith: Uncommon Presentation Within Inflammatory Polyp
Hidden Fecalith: Uncommon Presentation Within Inflammatory Polyp
Competing interests Sebastian Stefanovic has received lecture fees ...
Identification of Crosstalk Genes Between Primary Sjögren’s Syndrome and Primary Biliary Cirrhosis by Transcriptome Analysis
Identification of Crosstalk Genes Between Primary Sjögren’s Syndrome and Primary Biliary Cirrhosis by Transcriptome Analysis
Growing evidence points a connection between Primary Sjögren's Syndrome (pSS) and Primary Biliary Cholangitis (PB...
Surgical Management of Groove Pancreatitis: Lessons Learnt and Long-Term Experience
Surgical Management of Groove Pancreatitis: Lessons Learnt and Long-Term Experience
Groove pancreatitis (GP) is a rare form of focal chronic pancreatitis characterized by inflammation in the anatomic space ...
Hepatic Subcapsular Hematoma Induced by Metastatic Tumors
Hepatic Subcapsular Hematoma Induced by Metastatic Tumors
Conflict of interest The authors disclose no conflicts. ...
Long Term Follow-Up of Patients with Cryoglobulinemia After Successful Treatment of Chronic C Virus Hepatitis
Long Term Follow-Up of Patients with Cryoglobulinemia After Successful Treatment of Chronic C Virus Hepatitis
Mixed cryoglobulinemia is one of the most important extrahepatic manifestations of chronic hepatitis C infection. We scree...
DDS Profile: Evan S. Dellon, MD, MPH
DDS Profile: Evan S. Dellon, MD, MPH
Dr. Dellon has received research funding from Adare/Ellodi, Allakos, Arena/Pfizer, AstraZeneca, Eupraxia, GSK, Meritage, M...
Hydrogen Sulfide Producers Drive a Diarrhea-Like Phenotype and a Methane Producer Drives a Constipation-Like Phenotype in Animal Models
Hydrogen Sulfide Producers Drive a Diarrhea-Like Phenotype and a Methane Producer Drives a Constipation-Like Phenotype in Animal Models
We recently demonstrated that diarrhea-predominant irritable bowel syndrome (IBS-D) subjects have higher relative abundanc...
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