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Targeting yes-associated protein to overcome imatinib resistance in gastrointestinal stromal tumor drug-tolerant persister cells
Targeting yes-associated protein to overcome imatinib resistance in gastrointestinal stromal tumor drug-tolerant persister cells
The tyrosine kinase inhibitor (TKI) imatinib targets KIT and PDGFRA, offering significant therapeutic benefits in advanced...
Time-sequential prediction of postoperative complications after gastric cancer surgery using machine learning: a multicenter cohort study
Time-sequential prediction of postoperative complications after gastric cancer surgery using machine learning: a multicenter cohort study
Although many studies have developed logistic regression models for predicting complications using preoperative and intrao...
Eligibility criteria in phase 3 randomized controlled trials in gastric cancer
Eligibility criteria in phase 3 randomized controlled trials in gastric cancer
The purpose of this study was to examine the eligibility criteria in phase 3 randomized controlled trials (RCTs) in gastri...
Development and validation of a prognostic model incorporating patient reported outcomes for advanced gastric and esophageal carcinoma (AGOC) using individual patient data from two AGITG randomized clinical trials
Development and validation of a prognostic model incorporating patient reported outcomes for advanced gastric and esophageal carcinoma (AGOC) using individual patient data from two AGITG randomized clinical trials
We developed and validated a prognostic model incorporating readily accessible clinicopathological data and specific patie...
Angiotensin receptor blocker and angiotensin-converting enzyme inhibitor use and survival in gastric cancer patients: a Finnish nationwide cohort study
Angiotensin receptor blocker and angiotensin-converting enzyme inhibitor use and survival in gastric cancer patients: a Finnish nationwide cohort study
The renin–angiotensin system (RAS) has been increasingly recognized to be associated with carcinogenesis and cancer ...
Minimally invasive versus open completion total gastrectomy for remnant gastric cancer: a nationwide propensity score-matched analysis
Minimally invasive versus open completion total gastrectomy for remnant gastric cancer: a nationwide propensity score-matched analysis
Minimally invasive surgery (MIS) is increasingly used for gastric cancer; however, its application to remnant gastric canc...
Clinical-radiomic prognostic model integrating staging before and after neoadjuvant chemotherapy in gastric cancer: a multicenter retrospective study
Clinical-radiomic prognostic model integrating staging before and after neoadjuvant chemotherapy in gastric cancer: a multicenter retrospective study
Tumor regression grade (TRG) and ypTNM are primarily employed to evaluate the efficacy of Neoadjuvant chemotherapy (NAC) i...
Classification based on tumor phenotypes enables the novel molecular characterization of esophagogastric junction cancer
Classification based on tumor phenotypes enables the novel molecular characterization of esophagogastric junction cancer
The incidence of esophagogastric junction (EGJ) cancer is increasing worldwide. Siewert type II EGJ cancer encompasses int...
Textbook outcome in gastrectomy: useful metric or moving target? A scoping review
Textbook outcome in gastrectomy: useful metric or moving target? A scoping review
Composite metrics including Textbook Outcome (TO) and Textbook Oncological Outcome (TOO) are increasingly utilised to asse...
Type 2 diabetes in patients undergoing gastric cancer surgery: areas requiring disease-specific glycemic management
Type 2 diabetes in patients undergoing gastric cancer surgery: areas requiring disease-specific glycemic management
This review provides a comprehensive analysis of phase-specific management strategies for type 2 diabetes (T2D) in patient...
Gallbladder edema as a clue to zolbetuximab-associated protein-losing enteropathy in gastric cancer: a case report
Gallbladder edema as a clue to zolbetuximab-associated protein-losing enteropathy in gastric cancer: a case report
We report a rare case of protein-losing enteropathy (PLE) during zolbetuximab treatment in a 73-year-old woman with Stage ...
Development of adenovirus-based oncolytic virus to induce EBV lytic reactivation
Development of adenovirus-based oncolytic virus to induce EBV lytic reactivation
Oncolytic viruses (OVs) selectively replicate in and lyse tumor cells. Epstein–Barr virus-associated gastric carcino...
Dynamic postoperative prognosis and follow-up optimization for gastric cancer patients after neoadjuvant therapy: a multicenter retrospective study
Dynamic postoperative prognosis and follow-up optimization for gastric cancer patients after neoadjuvant therapy: a multicenter retrospective study
Conditional survival (CS) estimates the probability of future survival based on time already survived. However, evidence r...
COPS5 inhibition synergizes with the antitumor effect of trastuzumab by PTEN upregulation in -amplified gastric cancer
COPS5 inhibition synergizes with the antitumor effect of trastuzumab by PTEN upregulation in -amplified gastric cancer
COP9 Signalosome Subunit 5 (COPS5) is a deubiquitinating enzyme that induces chemotherapy resistance. The role of COPS5 am...
Comparative efficacy and safety of tislelizumab and other programmed cell death protein 1 inhibitors in first-line treatment of advanced gastroesophageal cancers: a systematic review and network meta-analysis
Comparative efficacy and safety of tislelizumab and other programmed cell death protein 1 inhibitors in first-line treatment of advanced gastroesophageal cancers: a systematic review and network meta-analysis
Several programmed cell death protein-1 inhibitors are approved for the first-line treatment of advanced gastric/gastroeso...
Health-related quality-of-life outcomes with regorafenib in advanced gastric and esophagogastric junction cancer: results from the INTEGRATE trials
Health-related quality-of-life outcomes with regorafenib in advanced gastric and esophagogastric junction cancer: results from the INTEGRATE trials
The INTEGRATE trials evaluated regorafenib in advanced gastric and esophagogastric junction cancer (AGOC), a poor prognosi...
Clinical utility impact of DNA-based cytology using droplet digital methylation-specific PCR in gastric cancer
Clinical utility impact of DNA-based cytology using droplet digital methylation-specific PCR in gastric cancer
Peritoneal dissemination is a major cause of poor prognosis in gastric cancer (GC). Although conventional peritoneal lavag...
A gene-expression signature defines a subtype of Stomach Adenocarcinomas with low levels of Claudins and a high ratio of NF-YA long/NF-YA short splicing variants
A gene-expression signature defines a subtype of Stomach Adenocarcinomas with low levels of Claudins and a high ratio of NF-YA long/NF-YA short splicing variants
Claudin-3, Claudin-4, and Claudin-7 are expressed on the surface of epithelial cells. Their absence in neoplastic cells of...
Clinicopathological significance of JAK2, STAT3, and STAT4 expression in patients with gastric solid-type poorly differentiated adenocarcinoma: a retrospective study
Clinicopathological significance of JAK2, STAT3, and STAT4 expression in patients with gastric solid-type poorly differentiated adenocarcinoma: a retrospective study
The role of janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling remains unclear in gastri...
Investigating the role of inflammatory cytokines in mediating the effect of gut microbiota on gastrointestinal cancers: a mendelian randomization study
Investigating the role of inflammatory cytokines in mediating the effect of gut microbiota on gastrointestinal cancers: a mendelian randomization study
The purpose of this study is to explore the causal relationship between gut microbiota and gastrointestinal (GI) cancers a...
The relationship between the gastric cancer microbiome and clinicopathological factors: a metagenomic investigation from the 100,000 genomes project and The Cancer Genome Atlas
The relationship between the gastric cancer microbiome and clinicopathological factors: a metagenomic investigation from the 100,000 genomes project and The Cancer Genome Atlas
Findings from previous gastric cancer microbiome studies have been conflicting, potentially due to patient and/or tumor he...
Spatial organization of B lymphocytes and prognosis prediction in patients with gastric cancer
Spatial organization of B lymphocytes and prognosis prediction in patients with gastric cancer
Within the tumor microenvironment (TME), the association of B lymphocytes (B cells) with prognosis and therapy response in...
The impact of ADAMTS14 genetic polymorphisms and its function on susceptibility to and prognosis of gastric cancer in a Chinese Han population
The impact of ADAMTS14 genetic polymorphisms and its function on susceptibility to and prognosis of gastric cancer in a Chinese Han population
Single nucleotide polymorphisms (SNPs) are associated with various diseases, including gastric cancer. The ADAMTS14 gene i...
Robotic and laparoscopic gastrectomy for gastric cancer: comparative insights into perioperative performance and three-year survival outcomes
Robotic and laparoscopic gastrectomy for gastric cancer: comparative insights into perioperative performance and three-year survival outcomes
The primary treatment for gastric cancer (GC) is surgical resection, particularly for locally advanced cases. While laparo...
Comprehensive histopathological analysis of gastric cancer in European and Latin America populations reveals differences in PDL1, HER2, p53 and MUC6 expression
Comprehensive histopathological analysis of gastric cancer in European and Latin America populations reveals differences in PDL1, HER2, p53 and MUC6 expression
Gastric cancer (GC) burden is currently evolving with regional differences associated with complex behavioural, environmen...
Short-term outcomes of preoperative computed tomography angiography versus standard assessment in patients with BMI ≥ 25.0 kg/m2 undergoing laparoscopic gastrectomy: the GISSG20-01 randomized clinical trial
Short-term outcomes of preoperative computed tomography angiography versus standard assessment in patients with BMI ≥ 25.0 kg/m2 undergoing laparoscopic gastrectomy: the GISSG20-01 randomized clinical trial
Laparoscopic gastrectomy lacks hand-direct tactile sense and has a limited surgical field compared to laparotomy. Apart fr...
Hazard rates of recurrence for gastric cancer after curative resection: implications for postoperative surveillance
Hazard rates of recurrence for gastric cancer after curative resection: implications for postoperative surveillance
Identifying the most effective postoperative surveillance interval in patients with gastric cancer (GC) remains challengin...
Prevalence and clinicopathological features of microsatellite instability-high metastatic or recurrent gastric and esophagogastric junction cancer: WJOG13320GPS
Prevalence and clinicopathological features of microsatellite instability-high metastatic or recurrent gastric and esophagogastric junction cancer: WJOG13320GPS
Microsatellite instability (MSI)-high tumors represent a distinct, small-fraction subtype in esophagogastric junction canc...
Tumor infiltration of inactive CD8 + T cells was associated with poor prognosis in Gastric Cancer
Tumor infiltration of inactive CD8 + T cells was associated with poor prognosis in Gastric Cancer
Gastric cancer (GC) shows limited response to immune checkpoint inhibitors due to its complex tumor immune microenvironmen...
Synergistic effects of dihydroartemisinin and cisplatin on inducing ferroptosis in gastric cancer through GPX4 inhibition
Synergistic effects of dihydroartemisinin and cisplatin on inducing ferroptosis in gastric cancer through GPX4 inhibition
In the past several decades, cisplatin (DDP), in combination with other drugs, has been used as the mainstay chemotherapy ...
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