Masui T, Ito T, Komoto I, et al. Recent epidemiology of patients with gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NEN) in Japan: a population-based study. BMC Cancer. 2020;20(1):1104.
Article PubMed PubMed Central Google Scholar
Zheng R, Zhao H, An L, et al. Incidence and survival of neuroendocrine neoplasms in China with comparison to the United States. Chin Med J (Engl). 2023;136(10):1216–24.
Rinke A, Wittenberg M, Schade-Brittinger C, et al. Placebo-controlled, double-blind, prospective, randomized study on the effect of octreotide LAR in the control of tumor growth in patients with metastatic neuroendocrine midgut tumors (PROMID): results of long-term survival. Neuroendocrinology. 2017;104(1):26–32.
Article PubMed CAS Google Scholar
Caplin ME, Pavel M, Phan AT, et al. Lanreotide autogel/depot in advanced enteropancreatic neuroendocrine tumours: final results of the CLARINET open-label extension study. Endocrine. 2021;71(2):502–13.
Article PubMed CAS Google Scholar
Caplin ME, Pavel M, Ruszniewski P. Lanreotide in metastatic enteropancreatic neuroendocrine tumors. N Engl J Med. 2014;371(16):1556–7.
Alonso-Gordoa T, Manneh R, Grande E, et al. High-dose somatostatin analogs for the treatment of neuroendocrine neoplasms: where are we now? Curr Treat Options Oncol. 2022;23(7):1001–13.
Cho MY, Kim JM, Sohn JH, Gastrointestinal Pathology Study Group of Korean Society of Pathologists, et al. Current trends of the incidence and pathological diagnosis of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in Korea 2000–2009: Multicenter Study. Cancer Res Treat. 2012;44(3):157–65.
Article PubMed PubMed Central Google Scholar
Del Rivero J, Perez K, Kennedy EB, et al. Systemic Therapy for Tumor Control in Metastatic Well-Differentiated Gastroenteropancreatic Neuroendocrine Tumors: ASCO Guideline. J Clin Oncol. 2023;41(32):5049–67.
Oberg K, Akerström G, Rindi G, et al. Neuroendocrine gastroenteropancreatic tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2010;21(Suppl 5):v223–7.
Salek N, Shirvani Arani S, Bahrami Samani A, et al. Feasibility study for production and quality control of Yb-175 as a byproduct of no carrier added Lu-177 preparation for radiolabeling of DOTMP. Australas Phys Eng Sci Med. 2018;41(1):69–79.
Strosberg JR, Caplin ME, Kunz PL, et al. 177Lu-Dotatate plus long-acting octreotide versus high dose long-acting octreotide in patients with midgut neuroendocrine tumours (NETTER-1): final overall survival and long-term safety results from an open-label, randomised, controlled, phase 3 trial. Lancet Oncol. 2021;22(12):1752–63.
Article PubMed CAS Google Scholar
Hennrich U, Kopka K. Lutathera®: The First FDA- and EMA-Approved Radiopharmaceutical for Peptide Receptor Radionuclide Therapy. Pharmaceuticals (Basel). 2019;12(3):114.
Article PubMed CAS Google Scholar
Singh S, Halperin D, Myrehaug S, et al. [177Lu]Lu-DOTA-TATE plus long-acting octreotide versus high-dose long-acting octreotide for the treatment of newly diagnosed, advanced grade 2–3, well-differentiated, gastroenteropancreatic neuroendocrine tumours (NETTER-2): an open-label, randomised, phase 3 study. Lancet. 2024;403(10446):2807–17.
Article PubMed CAS Google Scholar
Ichikawa Y, Kobayashi N, Takano S, et al. Neuroendocrine tumor theranostics. Cancer Sci. 2022;113(6):1930–8.
Article PubMed PubMed Central CAS Google Scholar
Kim SJ, Pak K, Koo PJ, et al. The efficacy of (177)Lu-labelled peptide receptor radionuclide therapy in patients with neuroendocrine tumours: a meta-analysis. Eur J Nucl Med Mol Imaging. 2015;42(13):1964–70.
Article PubMed CAS Google Scholar
Dannoon SF, Alenezi SA, Elgazzar AH. The efficacy of the available peptide receptor radionuclide therapy for neuroendocrine tumors: a meta-analysis. Nucl Med Commun. 2017;38(12):1085–93.
Ahmadi Bidakhvidi N, Goffin K, Dekervel J, et al. Peptide receptor radionuclide therapy targeting the somatostatin receptor: basic principles, clinical applications and optimization strategies. Cancers (Basel). 2021;14(1):129.
McClellan K, Chen EY, Kardosh A, et al. Therapy resistant gastroenteropancreatic neuroendocrine tumors. Cancers (Basel). 2022;14(19):4769.
Article PubMed CAS Google Scholar
Ballal S, Yadav MP, Damle NA, et al. Concomitant 177Lu-DOTATATE and capecitabine therapy in patients with advanced neuroendocrine tumors: a long-term-outcome, toxicity, survival, and quality-of-life study. Clin Nucl Med. 2017;42(11):e457–66.
Ilett EE, Langer SW, Olsen IH, et al. Neuroendocrine carcinomas of the gastroenteropancreatic system: a comprehensive review. Diagnostics (Basel). 2015;5(2):119–76.
Article PubMed CAS Google Scholar
Bodei L, Kwekkeboom DJ, Kidd M, et al. Radiolabeled somatostatin analogue therapy of gastroenteropancreatic cancer. Semin Nucl Med. 2016;46(3):225–38.
Ezziddin S, Attassi M, Yong-Hing CJ, et al. Predictors of long-term outcome in patients with well-differentiated gastroenteropancreatic neuroendocrine tumors after peptide receptor radionuclide therapy with 177Lu-octreotate. J Nucl Med. 2014;55(2):183–90.
Article PubMed CAS Google Scholar
Severi S, Grassi I, Nicolini S, et al. Peptide receptor radionuclide therapy in the management of gastrointestinal neuroendocrine tumors: efficacy profile, safety, and quality of life. Onco Targets Ther. 2017;10:551–7.
Article PubMed PubMed Central CAS Google Scholar
Roosenburg S, Laverman P, van Delft FL, et al. Radiolabeled CCK/gastrin peptides for imaging and therapy of CCK2 receptor-expressing tumors. Amino Acids. 2011;41(5):1049–58.
Article PubMed CAS Google Scholar
Gotthardt M, Béhé MP, Grass J, et al. Added value of gastrin receptor scintigraphy in comparison to somatostatin receptor scintigraphy in patients with carcinoids and other neuroendocrine tumours. Endocr Relat Cancer. 2006;13(4):1203–11.
Pouget JP, Navarro-Teulon I, Bardiès M, et al. Clinical radioimmunotherapy–the role of radiobiology. Nat Rev Clin Oncol. 2011;8(12):720–34.
Article PubMed CAS Google Scholar
Salih S, Alkatheeri A, Alomaim W, et al. Radiopharmaceutical treatments for cancer therapy, radionuclides characteristics, applications, and challenges. Molecules. 2022;27(16):5231.
Article PubMed PubMed Central CAS Google Scholar
Song H, Sgouros G. Alpha and beta radiation for theragnostics. PET Clin. 2024;19(3):307–23.
Al-Toubah T, Sikaria D, Jesurajan J, et al. Comparison of nausea and vomiting associated with amino acid formulations coinfused with peptide receptor radionuclide therapy: commercial parenteral nutrition formulas versus compounded arginine/lysine. Pancreas. 2021;50(4):513–5.
Article PubMed CAS Google Scholar
Kesavan M, Turner JH. Myelotoxicity of peptide receptor radionuclide therapy of neuroendocrine tumors: a decade of experience. Cancer Biother Radiopharm. 2016;31(6):189–98.
Kratochwil C, Giesel FL, Bruchertseifer F, et al. 213Bi-DOTATOC receptor-targeted alpha-radionuclide therapy induces remission in neuroendocrine tumours refractory to beta radiation: a first-in-human experience. Eur J Nucl Med Mol Imaging. 2014;41(11):2106–19.
Article PubMed PubMed Central CAS Google Scholar
Ballal S, Yadav MP, Tripathi M,et al. Survival outcomes in metastatic gastroenteropancreatic neuroendocrine tumor patients receiving concomitant 225Ac-DOTATATE targeted alpha therapy and capecitabine: a real-world scenario management based long-term outcome study. J Nucl Med. 2022:jnumed.122.264043.
Demirci E, Alan Selçuk N, Beydağı G, et al. Initial findings on the use of [225Ac]Ac-DOTATATE therapy as a theranostic application in patients with neuroendocrine tumors. Mol Imaging Radionucl Ther. 2023;32(3):226–32.
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