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Management of skull base meningiomas with extracranial extension: resection, recurrence, and prognostic factors
Management of skull base meningiomas with extracranial extension: resection, recurrence, and prognostic factors
To assess clinical, radiographic, surgical, and pathological factors affecting outcomes in patients with skull-base mening...
Long-term clinical outcomes of bevacizumab for treatment of stereotactic radiosurgery-induced radiation necrosis in patients with brain metastases
Long-term clinical outcomes of bevacizumab for treatment of stereotactic radiosurgery-induced radiation necrosis in patients with brain metastases
Radiation necrosis (RN) is a potentially debilitating complication of stereotactic radiosurgery (SRS) for brain metastases...
Evaluation of clinical and volumetric outcomes following adaptive gamma knife radiosurgery for brain metastases
Evaluation of clinical and volumetric outcomes following adaptive gamma knife radiosurgery for brain metastases
Hypofractionated stereotactic radiosurgery is an effective technique to treat larger brain metastases and post-surgical ca...
Independent histological validation of MR-derived radio-pathomic maps of tumor cell density using image-guided biopsies in human brain tumors
Independent histological validation of MR-derived radio-pathomic maps of tumor cell density using image-guided biopsies in human brain tumors
In brain gliomas, non-invasive biomarkers reflecting tumor cellularity would be useful to guide supramarginal resections a...
Postoperative hydrocephalus in patients with infratentorial brain metastases may be influenced by preoperative treatment: a single-center cohort study
Postoperative hydrocephalus in patients with infratentorial brain metastases may be influenced by preoperative treatment: a single-center cohort study
Infratentorial brain metastases (BM), particularly those causing obstruction of the fourth ventricle, are associated with ...
Shared decision-making interventions in neuro-oncology practice: a systematic review
Shared decision-making interventions in neuro-oncology practice: a systematic review
Shared decision-making (SDM) has been shown to be beneficial to patients and improve health outcomes. While more research ...
Cesium-131 collagen tile brachytherapy for salvage of recurrent intracranial metastases
Cesium-131 collagen tile brachytherapy for salvage of recurrent intracranial metastases
Management of brain metastases (BM) that recur after stereotactic radiosurgery (SRS) (rBM) is challenging. We reviewed our...
Glioblastoma cell motility and invasion is regulated by membrane-associated heat shock protein Hsp70
Glioblastoma cell motility and invasion is regulated by membrane-associated heat shock protein Hsp70
Membrane-associated heat shock protein 70 kDa (mHsp70) is specifically localized on the plasma membrane of variou...
Impact of proton versus photon radiotherapy on overall survival in the management of spinal chordoma and mortality risk prediction: a nationwide analysis
Impact of proton versus photon radiotherapy on overall survival in the management of spinal chordoma and mortality risk prediction: a nationwide analysis
This study aims to provide a national-level insight into the optimal management of spinal chordoma, a type of rare and com...
Molecular and clinical determinants of response to checkpoint inhibitor immunotherapy in glioblastoma
Molecular and clinical determinants of response to checkpoint inhibitor immunotherapy in glioblastoma
While checkpoint inhibitor therapy (CPI) has transformed treatment in multiple solid tumors, its efficacy in glioblastoma ...
CPT-SIOP registry: evaluation of risk factors for disease progression in pediatric choroid plexus papilloma
CPT-SIOP registry: evaluation of risk factors for disease progression in pediatric choroid plexus papilloma
Choroid plexus papilloma (CPP) and atypical choroid plexus papilloma (aCPP) have excellent outcomes. However, some CPP/aCP...
Posterior parasagittal meningiomas display aggressive features independent of size: a multicenter analysis
Posterior parasagittal meningiomas display aggressive features independent of size: a multicenter analysis
While meningioma size is known to correlate with higher histological grade, tumor behavior can vary by anatomical location...
Outcomes of leptomeningeal disease after only vertebral osseous metastases: a real-world analysis using the TriNetX database
Outcomes of leptomeningeal disease after only vertebral osseous metastases: a real-world analysis using the TriNetX database
Leptomeningeal disease (LMD) is a morbid complication of systemic cancer typically associated with brain metastases. Howev...
Beyond surgical radicality in intramedullary spinal cord metastases: neurological function and systemic disease burden drive patient outcomes
Beyond surgical radicality in intramedullary spinal cord metastases: neurological function and systemic disease burden drive patient outcomes
Intramedullary spinal cord metastases (ISCM) are rare, clinically challenging lesions with limited evidence-based guidance...
Study of 18 F-fluciclovine PET for serial assessment of glioblastoma tumor volumes during surgery and radiotherapy
Study of 18 F-fluciclovine PET for serial assessment of glioblastoma tumor volumes during surgery and radiotherapy
Recent evidence supports incorporating 18 F-Fluciclovine PET for glioblastoma treatment planning and monitoring, ...
Anatomical distribution and prognostic heterogeneity in glioma: unique clinical features of occipital glioblastoma
Anatomical distribution and prognostic heterogeneity in glioma: unique clinical features of occipital glioblastoma
Adult-type diffuse gliomas, particularly IDH-wildtype glioblastoma, exhibit significant differences in incidence across br...
Cystic glioblastoma IDH-wildtype: genetic alterations and outcomes
Cystic glioblastoma IDH-wildtype: genetic alterations and outcomes
In the past decade, studies have reclassified infiltrating glioblastomas (GBM) IDH-wildtype utilizing molecular and phenot...
RFX2 promotes tumor cell stemness through epigenetic regulation of PAF1 in spinal ependymoma
RFX2 promotes tumor cell stemness through epigenetic regulation of PAF1 in spinal ependymoma
Spinal ependymoma (SE) is a rare tumor that is most commonly low-grade and tends to recur when complete tumor resection is...
Focused ultrasound combined with radiotherapy for malignant brain tumor: a preclinical and clinical study
Focused ultrasound combined with radiotherapy for malignant brain tumor: a preclinical and clinical study
Blood–brain barrier (BBB) remains to be the major obstacle to conquer in treating patients with malignant brain tumo...
Ganciclovir as a potential treatment for glioma: a systematic review and meta-analysis
Ganciclovir as a potential treatment for glioma: a systematic review and meta-analysis
Glioma is a challenging malignant tumor with a low survival rate and no effective treatment. Recently, ganciclovir, an ant...
Management strategies for intracranial progression in ALK-positive non-small cell lung cancer: a real-world cohort study
Management strategies for intracranial progression in ALK-positive non-small cell lung cancer: a real-world cohort study
ALK-positive NSCLC patients exhibit a particularly high propensity for the development of brain metastases. Current guidel...
Incidental meningiomas: a current and increasingly common challenge
Incidental meningiomas: a current and increasingly common challenge
Näslund O, Strand PS, Solheim O et al (2023) Incidence, management, and outcome of incidental meningioma: what has happene...
Treatment of very elderly glioblastoma patients ≥ 75 years of age: whom to treat
Treatment of very elderly glioblastoma patients ≥ 75 years of age: whom to treat
The prognosis of patients ≥ 75 years suffering from glioblastoma is poor. Novel therapies are usually re...
Pyruvate kinase M2 (PKM-2) expression and prognostic significance in glioblastoma patients
Pyruvate kinase M2 (PKM-2) expression and prognostic significance in glioblastoma patients
Pyruvate kinase M2 (PKM2) is a key enzyme that catalyzes the irreversible and final step of glycolysis. It is closely asso...
A multi-site phase I trial of Veliparib with standard radiation and temozolomide in patients with newly diagnosed glioblastoma multiforme (GBM)
A multi-site phase I trial of Veliparib with standard radiation and temozolomide in patients with newly diagnosed glioblastoma multiforme (GBM)
A multi-site Phase I trial was conducted to determine the safety, maximum tolerated dose, and pharmacokinetics (PK) of Vel...
Development of a “Geo-Tagged” tumor sample registry: intra-operative linkage of sample location to imaging
Development of a “Geo-Tagged” tumor sample registry: intra-operative linkage of sample location to imaging
There is a growing body of literature documenting glioma heterogeneity in terms of radiographic, histologic, molecular, an...
Liquid biopsy in the setting of leptomeningeal metastases: a systematic review and meta-analysis
Liquid biopsy in the setting of leptomeningeal metastases: a systematic review and meta-analysis
The blood-brain barrier can prevent circulating tumor DNA (ctDNA) derived from the central nervous system from entering th...
Targeted immunotherapy for glioblastoma involving whole tumor-derived autologous cells in the upfront setting after craniotomy
Targeted immunotherapy for glioblastoma involving whole tumor-derived autologous cells in the upfront setting after craniotomy
To date, immunotherapeutic approaches in glioblastoma (GBM) have had limited clinical efficacy as compared to other solid ...
Treatment and survival of patients with small cell lung cancer and brain metastasis
Treatment and survival of patients with small cell lung cancer and brain metastasis
To elucidate treatment patterns and their outcomes in patients with small cell lung cancer (SCLC) and brain metastasis (BM...
Effects of intrathecal pemetrexed on the survival of patients with leptomeningeal metastasis from lung adenocarcinoma: a propensity score matching analysis
Effects of intrathecal pemetrexed on the survival of patients with leptomeningeal metastasis from lung adenocarcinoma: a propensity score matching analysis
To explore the impact of intrathecal pemetrexed (IP) on the survival of lung adenocarcinoma (LUAC) patients with leptomeni...
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