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Red wavelength-induced photobiomodulation enhances indocyanine green-based anticancer photodynamic therapy
Red wavelength-induced photobiomodulation enhances indocyanine green-based anticancer photodynamic therapy
Cancer is a global concern worldwide. Prostate cancer has high prevalence and mortality rates among men. Photodynamic ther...
Targeting the mevalonate pathway enhances the efficacy of 5-fluorouracil by regulating pyroptosis
Targeting the mevalonate pathway enhances the efficacy of 5-fluorouracil by regulating pyroptosis
The 5-fluorouracil (5-FU)-based chemotherapy regimen is a primary strategy for treating pancreatic cancer (PC). However, c...
Dual roles of extracellular vesicles in acute lymphoblastic leukemia: implications for disease progression and theranostic strategies
Dual roles of extracellular vesicles in acute lymphoblastic leukemia: implications for disease progression and theranostic strategies
Acute Lymphoblastic Leukemia (ALL) is a heterogeneous blood cancer characterized by the uncontrolled growth of immature ly...
N6-methyladenosine RNA modification in head and neck squamous cell carcinoma (HNSCC): current status and future insights
N6-methyladenosine RNA modification in head and neck squamous cell carcinoma (HNSCC): current status and future insights
N6-methyladenosine (m6A) plays a pivotal role in regulating epitranscriptomic mechanisms and is closely linked to the norm...
An overview on the interaction between non-coding RNAs and CTLA-4 gene in human diseases
An overview on the interaction between non-coding RNAs and CTLA-4 gene in human diseases
Cytotoxic T lymphocyte antigen 4 (CTLA-4), in conjunction with PD-1 and CD28, plays a pivotal role in the modulation of T-...
Exploring the role of antigen-presenting cancer-associated fibroblasts and CD74 on the pancreatic ductal adenocarcinoma tumor microenvironment
Exploring the role of antigen-presenting cancer-associated fibroblasts and CD74 on the pancreatic ductal adenocarcinoma tumor microenvironment
Pancreatic ductal adenocarcinoma (PDAC) has proven to be a formidable cancer primarily due to its tumor microenvironment (...
Telomerase inhibition in breast cancer and breast cancer stem cells: a brief review
Telomerase inhibition in breast cancer and breast cancer stem cells: a brief review
Breast cancer is a major health problem, accounting for one third of all cancers in women. There is no definitive treatmen...
Associations between the life’s essential 8, genetic risk and breast cancer incidence in premenopausal and postmenopausal women: a prospective study in UK Biobank
Associations between the life’s essential 8, genetic risk and breast cancer incidence in premenopausal and postmenopausal women: a prospective study in UK Biobank
The combined effect of cardiovascular risk factors on breast cancer in women is unknown. The relationship between genetic ...
Exosomes in esophageal cancer: function and therapeutic prospects
Exosomes in esophageal cancer: function and therapeutic prospects
Esophageal cancer (EC) is one of the most common malignant tumors worldwide. Exosomes are a type of extracellular vesicles...
The AXL-mediated modulation of myeloid-derived suppressor cells (MDSC) in nasopharyngeal carcinoma
The AXL-mediated modulation of myeloid-derived suppressor cells (MDSC) in nasopharyngeal carcinoma
AXL has ubiquitous expression in multiple cancers, and is strongly linked to both tumor progression, metastasis, and poor ...
Investigation of anticancer potential of a novel bioactive molecule from Trichosporon asahii VITSTB1 in breast cancer cell lines: an in vitro study
Investigation of anticancer potential of a novel bioactive molecule from Trichosporon asahii VITSTB1 in breast cancer cell lines: an in vitro study
The current study investigates the anticancer activity of protein derived from yeast against breast cancer. Yeast-derived ...
The physician payments Sunshine Act and medical oncology: a seven-year financial analysis
The physician payments Sunshine Act and medical oncology: a seven-year financial analysis
The integration of pharmaceutical and medical device companies with clinical practice is under scrutiny due to financial i...
Co-culture system of breast cancer and normal cells to investigate inflammation: using doxorubicin encapsulated in adipose-derived exosomes
Co-culture system of breast cancer and normal cells to investigate inflammation: using doxorubicin encapsulated in adipose-derived exosomes
Doxorubicin (DOX) chemotherapy for breast cancer is an effective treatment option, but it also has disadvantages. Exosomes...
Cedrus atlantica extract inhibits melanoma progression by suppressing epithelial-mesenchymal transition and inducing mitochondria-mediated apoptosis
Cedrus atlantica extract inhibits melanoma progression by suppressing epithelial-mesenchymal transition and inducing mitochondria-mediated apoptosis
Melanoma has a low incidence, accounting for less than 5% of skin cancers; however, it is the most lethal cancer, primaril...
Metabolic dysregulation in myelodysplastic neoplasm: impact on pathogenesis and potential therapeutic targets
Metabolic dysregulation in myelodysplastic neoplasm: impact on pathogenesis and potential therapeutic targets
Despite significant advancements in the research of the pathogenesis mechanisms of Myelodysplastic Neoplasm (MDS) in recen...
Betulinic acid and oleanolic acid modulate CD81 expression and induce apoptosis in triple-negative breast cancer cells through ROS generation
Betulinic acid and oleanolic acid modulate CD81 expression and induce apoptosis in triple-negative breast cancer cells through ROS generation
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by a lack of hormones recepto...
Progression and perspectives in disease modeling for Juvenile myelomonocytic leukemia
Progression and perspectives in disease modeling for Juvenile myelomonocytic leukemia
Juvenile myelomonocytic leukemia (JMML) is a rare myeloproliferative neoplasm occurring in infants and young children. JMM...
Metal–organic frameworks as nanoplatforms for combination therapy in cancer treatment
Metal–organic frameworks as nanoplatforms for combination therapy in cancer treatment
The integration of nanotechnology into cancer treatment has revolutionized chemotherapy, boosted its effectiveness while r...
Moving beyond cisplatin resistance: mechanisms, challenges, and prospects for overcoming recurrence in clinical cancer therapy
Moving beyond cisplatin resistance: mechanisms, challenges, and prospects for overcoming recurrence in clinical cancer therapy
Cisplatin, a classical platinum-based chemotherapy agent, has been a frontline treatment for various cancers for decades. ...
Oncolytic viruses improve cancer immunotherapy by reprogramming solid tumor microenvironment
Oncolytic viruses improve cancer immunotherapy by reprogramming solid tumor microenvironment
Immunotherapies using immune checkpoint inhibitors (ICIs) and chimeric antigen receptor (CAR) T-cell therapy have achieved...
Upregulation of CELSR1 expression promotes ovarian cancer cell proliferation, migration, and invasion
Upregulation of CELSR1 expression promotes ovarian cancer cell proliferation, migration, and invasion
Cadherin epidermal growth factor and laminin-G seven-pass G-type receptor 1 (CELSR1) is a planar cell polarity protein inv...
Enhanced therapeutic efficacy of doxorubicin/cyclophosphamide in combination with pitavastatin or simvastatin against breast cancer cells
Enhanced therapeutic efficacy of doxorubicin/cyclophosphamide in combination with pitavastatin or simvastatin against breast cancer cells
Fighting breast tumors mandates finding different agents devoid of chemotherapy side effects. Repurposing existing drugs, ...
Emerging treatment approaches for triple-negative breast cancer
Emerging treatment approaches for triple-negative breast cancer
Approximately, 15% of global breast cancer cases are diagnosed as triple-negative breast cancer (TNBC), identified as the ...
n-3 PUFAs synergistically enhance the efficacy of doxorubicin by inhibiting the proliferation and invasion of breast cancer cells
n-3 PUFAs synergistically enhance the efficacy of doxorubicin by inhibiting the proliferation and invasion of breast cancer cells
Breast cancer stands as a prominent contributor to cancer-related fatalities among women globally, characterized by an unf...
Chitosan-encapsulated naringenin promotes ROS mediated through the activation of executioner caspase-3
Chitosan-encapsulated naringenin promotes ROS mediated through the activation of executioner caspase-3
We previously reported that chitosan nanoparticle-encapsulated Naringenin (CS-NPs/NAR) could scavenge free radicals at low...
Comprehensive genomic profiling for oncological advancements by precision medicine
Comprehensive genomic profiling for oncological advancements by precision medicine
Considerable advancements in next generation sequencing (NGS) techniques have sparked the use of comprehensive genomic pro...
Examining the effect of activated cytotoxic (CD8+) T-cell exosomes to the lung cancer
Examining the effect of activated cytotoxic (CD8+) T-cell exosomes to the lung cancer
Lung cancer continues to be a major health problem worldwide owing to its incidence, and causes physical, psychological, s...
Efficacy and safety of Huachansu combined with adjuvant chemotherapy in resected colorectal cancer patients: a prospective, open-label, randomized phase II study
Efficacy and safety of Huachansu combined with adjuvant chemotherapy in resected colorectal cancer patients: a prospective, open-label, randomized phase II study
Although some studies in China have suggested Huachansu (HCS) combined with chemotherapy is effective in the treatment of ...
Mechanism of anticancer effect of ETP-45658, a PI3K/AKT/mTOR pathway inhibitor on HT-29 Cells
Mechanism of anticancer effect of ETP-45658, a PI3K/AKT/mTOR pathway inhibitor on HT-29 Cells
The PI3K pathway plays a crucial role in tumor cell proliferation across various cancers, including colon cancer, making i...
Cancer stemness kinase inhibitor amcasertib: a promising therapeutic agent in ovarian cancer stem and cancer cell models with different genetic profiles
Cancer stemness kinase inhibitor amcasertib: a promising therapeutic agent in ovarian cancer stem and cancer cell models with different genetic profiles
Ovarian cancer, often referred to as the ‘silent killer,’ is a significant contributor to mortality rates. Eme...
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