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Sarcomatoid carcinoma of the common bile duct: A case report and review of the literature
Sarcomatoid carcinoma of the common bile duct: A case report and review of the literature
Sarcomatoid carcinoma of the common bile duct is an exceptionally rare malignancy, with only eight cases previously report...
A case of poorly differentiated thyroid carcinoma harboring an mutation
A case of poorly differentiated thyroid carcinoma harboring an mutation
SWItch/sucrose non-fermentable (SWI/SNF) chromatin-remodeling complexes regulate nucleosome positioning. Its involvement h...
Pregnancy after fertility preservation and multimodal therapy including intensity-modulated radiotherapy for recurrent vulvar cancer: A case report
Pregnancy after fertility preservation and multimodal therapy including intensity-modulated radiotherapy for recurrent vulvar cancer: A case report
Advanced or recurrent vulvar cancer in women of reproductive age is extremely rare, and the effects of radiotherapy (RT) o...
Unique pattern of endometrial invasion in gastric-type adenocarcinoma of the uterine cervix: a report of two cases
Unique pattern of endometrial invasion in gastric-type adenocarcinoma of the uterine cervix: a report of two cases
Gastric-type cervical adenocarcinoma (GAS), the most prevalent subtype of human papillomavirus (HPV)-independent cervical ...
Severe nail toxicity induced by FGFR inhibitor in -rearranged cholangiocarcinoma
Severe nail toxicity induced by FGFR inhibitor in -rearranged cholangiocarcinoma
FGFR2 gene fusions are identified in approximately 10–16% of patients with intrahepatic cholangiocarcinoma and are t...
Combination of re-irradiation and bevacizumab for recurrent adult histological pineoblastoma: a case report
Combination of re-irradiation and bevacizumab for recurrent adult histological pineoblastoma: a case report
Adult pineoblastoma is an uncommon malignant neoplasm. Relevant literature, particularly regarding its recurrence, is limi...
Ewing sarcoma of the frontal sinus in an elderly patient: a case report and review
Ewing sarcoma of the frontal sinus in an elderly patient: a case report and review
Ewing sarcoma is a malignant small round cell tumor with an aggressive clinical course that typically arises in the extrem...
Rapidly progressive synchronous multifocal gastrointestinal stenoses in bladder cancer: diagnostic challenges and clinical implications
Rapidly progressive synchronous multifocal gastrointestinal stenoses in bladder cancer: diagnostic challenges and clinical implications
Gastrointestinal involvement by bladder cancer is rare and typically presents as localized invasion. We report an exceptio...
A case of advanced esophagogastric junction cancer in which comprehensive genomic profiling by liquid biopsy led to the diagnosis of a second primary hepatocellular carcinoma
A case of advanced esophagogastric junction cancer in which comprehensive genomic profiling by liquid biopsy led to the diagnosis of a second primary hepatocellular carcinoma
The primary objective of comprehensive genomic profiling (CGP) is to identify actionable genomic alterations. We report a ...
Palliative total kidney irradiation for acute kidney injury caused by bilateral renal infiltration of chemotherapy-resistant mantle cell lymphoma: a case report
Palliative total kidney irradiation for acute kidney injury caused by bilateral renal infiltration of chemotherapy-resistant mantle cell lymphoma: a case report
Mantle cell lymphoma (MCL) is a rare subtype of B-cell non-Hodgkin lymphoma, and acute kidney injury (AKI) from direct ren...
Maintaining complete response to avelumab for lung metastases from native ureteral cancer after kidney transplantation: a case report
Maintaining complete response to avelumab for lung metastases from native ureteral cancer after kidney transplantation: a case report
We report the first case of metastatic urothelial carcinoma (mUC) in a kidney transplant recipient who was successfully tr...
A case of successful combined intensity-modulated radiation therapy and hyperthermia for a large, drug-resistant chest wall recurrence of breast cancer
A case of successful combined intensity-modulated radiation therapy and hyperthermia for a large, drug-resistant chest wall recurrence of breast cancer
Chest wall recurrence (CWR) of breast cancer that is large and resistant to multiple systemic therapies requires rapid and...
Two successful deliveries following fertility-sparing treatment for synchronous endometrial and ovarian cancer: a case report and literature review
Two successful deliveries following fertility-sparing treatment for synchronous endometrial and ovarian cancer: a case report and literature review
Fertility-sparing treatment is a viable treatment option for selected patients with endometrial or ovarian cancer. However...
A giant testicular tumor requiring skin valvuloplasty
A giant testicular tumor requiring skin valvuloplasty
Giant testicular tumors, typically defined as those with volumes exceeding ten times the normal testicular volume, are ext...
An autopsy case of sigmoid colon cancer with multiple cerebral infarctions associated with drug-induced interstitial lung disease: a case implicating local PAI-1 overexpression
An autopsy case of sigmoid colon cancer with multiple cerebral infarctions associated with drug-induced interstitial lung disease: a case implicating local PAI-1 overexpression
A 68-year-old Japanese man receiving panitumumab-containing chemotherapy for metastatic sigmoid colon cancer presented wit...
Molecular pathology provides significant insights into the diagnosis and treatment of cancer of unknown primary origin: a case report of an extremely rare male occult breast apocrine cancer
Molecular pathology provides significant insights into the diagnosis and treatment of cancer of unknown primary origin: a case report of an extremely rare male occult breast apocrine cancer
We present a case of occult apocrine breast cancer in a man presenting with back pain and multiple bone and large liver me...
Adenocarcinoma with endometrioid features originating in the male genitourinary tract after hormonal therapy for prostate cancer
Adenocarcinoma with endometrioid features originating in the male genitourinary tract after hormonal therapy for prostate cancer
We report a rare case of adenocarcinoma with endometrioid features in an 80-year-old male with a history of long-term horm...
Radiation-induced myocardial metabolic impairment detected by ¹²³I-BMIPP/⁹⁹ᵐTc-MIBI metabolic–perfusion mismatch following thoracic radiotherapy for thymoma: a case report
Radiation-induced myocardial metabolic impairment detected by ¹²³I-BMIPP/⁹⁹ᵐTc-MIBI metabolic–perfusion mismatch following thoracic radiotherapy for thymoma: a case report
Radiation-induced heart disease is a well-recognized late complication of thoracic radiotherapy and comprises a broad spec...
Acinic cell carcinoma of the breast in a patient with a pathogenic variant: a case report
Acinic cell carcinoma of the breast in a patient with a pathogenic variant: a case report
Acinic cell carcinoma (ACC) of the breast is a rare subtype of breast cancer, and its clinicopathological and molecular ch...
Clinical utility of diagnostic laparoscopy for ovarian metastasis from breast cancer in a -mutated patient with hereditary breast and ovarian cancer syndrome: a case report and literature review
Clinical utility of diagnostic laparoscopy for ovarian metastasis from breast cancer in a -mutated patient with hereditary breast and ovarian cancer syndrome: a case report and literature review
Ovarian metastasis from breast cancer has been reported in a substantial number of cases; however, reports that specifical...
Prophylactic use of duloxetine hydrochloride in oxaliplatin-induced first-bite syndrome
Prophylactic use of duloxetine hydrochloride in oxaliplatin-induced first-bite syndrome
First-bite syndrome (FBS) is manifested as acute and severe pain in the parotid region occurring at the first bite of a me...
Successful immunotherapy with ipilimumab and nivolumab in a patient with pulmonary sclerosing pneumocytoma
Successful immunotherapy with ipilimumab and nivolumab in a patient with pulmonary sclerosing pneumocytoma
Pulmonary sclerosing pneumocytoma (PSP) is a rare form of lung cancer that occasionally presents with lymph node and extra...
Successful osimertinib treatment for Meckel’s cave metastasis: a case report
Successful osimertinib treatment for Meckel’s cave metastasis: a case report
Osimertinib has emerged as the standard first-line treatment for advanced non-small cell lung cancer (NSCLC) with EGFR mut...
Reduction of bleeding by cabozantinib in metastatic renal cell carcinoma with hereditary hemorrhagic telangiectasia
Reduction of bleeding by cabozantinib in metastatic renal cell carcinoma with hereditary hemorrhagic telangiectasia
Hereditary hemorrhagic telangiectasia (HHT) is a rare genetic disorder characterized by refractory recurrent epistaxis and...
Colorectal anastomotic leakage after conversion surgery for advanced endometrial cancer treated with lenvatinib plus pembrolizumab: a case report
Colorectal anastomotic leakage after conversion surgery for advanced endometrial cancer treated with lenvatinib plus pembrolizumab: a case report
The combination therapy of lenvatinib plus pembrolizumab (LP) is increasingly recognized as an important second-line regim...
SMARCA4-deficient epithelioid sarcoma revealed by comprehensive genomic profiling, leading to a notable response by nivolumab treatment
SMARCA4-deficient epithelioid sarcoma revealed by comprehensive genomic profiling, leading to a notable response by nivolumab treatment
A 50-year-old man presented with a bulky mass in the left thigh and was referred to our department. He showed an impaired ...
Ponatinib and prednisolone induce sustained remission in a relapsed case of mixed-phenotype acute leukemia with BCR::ABL1 fusion intolerant to dasatinib
Ponatinib and prednisolone induce sustained remission in a relapsed case of mixed-phenotype acute leukemia with BCR::ABL1 fusion intolerant to dasatinib
Mixed-phenotype acute leukemia (MPAL) with BCR::ABL1 fusion is a rare leukemia subtype exhibiting both myeloid and lymphoi...
Resistant PRL-secreting PitNET associated with breast carcinoma: a case report and literature review
Resistant PRL-secreting PitNET associated with breast carcinoma: a case report and literature review
In several studies, hyperprolactinemia has been associated with increased breast cancer risk. Evidence shows that prolacti...
Squamous cell carcinoma in a long-standing suprapubic cystostomy: a urological oddball
Squamous cell carcinoma in a long-standing suprapubic cystostomy: a urological oddball
Squamous cell carcinoma (SCC) rarely accounts for 2–5% of urinary bladder cancer. Chronic irritation of the bladder ...
Long-term conservative treatment of chylous ascites in gynecological malignant surgery: a case report and literature review
Long-term conservative treatment of chylous ascites in gynecological malignant surgery: a case report and literature review
Chylous ascites is a rare complication of abdominal surgery. Although most patients show improvement with conservative tre...
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