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Investigating the Role of Escherichia coli Infection in the Pathogenesis of Bladder Cancer: A Comparative Genomics Interaction
Background: Bladder cancer (BC) is the 10th most common cancer worldwide. Microorganisms, including bacteria, may contribu...
Comparison Anticancer Effects of Platinum Ribavirin with Platinum Azidothymidine via Telomerase, Bcl-2, miRNA-21 and miRNA-122 Biomarkers Genes Expression on HepG2 Cancer Cell Lines
Background: Anticancer medication assessment is performed by numerous approaches including biomarkers gene expression. Thi...
Oridonin Enhances Radiotherapy Efficacy by Inducing Late-Stage Cell Death and G2/M Arrest in U87MG Glioma Cells
Background: Glioblastoma multiforme is a deadly brain tumor with limited treatment options. The aim of this study was to i...
Gefitinib Combination with Radiotherapy in Patients with Local Advanced Non-Small Cell Lung Cancer
Background: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors is a crucial agent in EGFR-mutated advanced...
A Dosimetric Study of Accidental Internal Mammary Lymph Node Irradiation during Locoregional Breast Irradiation
Background: One remaining grey zone in locoregional breast irradiation is whether to irradiate internal mammary lymph node...
Evaluation of the Prognostic Role of Leptin and Cyclin D1 Expression in Colorectal Cancer
Background: Colorectal cancer (CRC) is one of the most malignancies worldwide. This study aimed to determine the role of l...
Comparison of Interleukin-18 Serum Levels in Patients with Breast Cancer and Idiopathic Granulomatous Mastitis
Background: Breast cancer (BC), as a global challenge, is one of the most prevalent malignant diseases among women. Idiopa...
Urothelial Carcinoma Stage and Grade Association with the Expression Levels of Eukaryotic Initiation Factor 4E and 4E Binding Protein 1
Background: Bladder cancer (BCa) accounts for the fourth most common cancer among men. Eukaryote translation initiation fa...
Flaxseed Extract Can Modulates Apoptotic Genes to Promote Cell Death in Breast Cancer Cells
Background: Breast cancer is a multifactorial malignancy with uncertain treatment outcomes that make its challenging treat...
Evaluation of Potential miR-221, miR-93, miR-21, and miR-24 as Molecular Markers for Laryngeal Squamous Cell Carcinoma
Background: Laryngeal cancer, the most prevalent head and neck malignancy, represents 2.4% of all tumors and is the 11th m...
Feature Selection Algorithms Combined with Experimental Validation Reveal COL10A1 and TMPRSS4 Genes as Potential Diagnostic Biomarkers in Pancreatic Ductal Adenocarcinoma
Background: Pancreatic adenocarcinoma (PAAD) is often diagnosed at a late stage, preventing curative surgery. Early detect...
Prevalence and Clinicopathologic Features of HER2 Overexpression in Endocervical Adenocarcinoma
Background: Endocervical adenocarcinoma (ENCA) has poor prognosis and is increasing in developing countries. Human epiderm...
Nettle (Urtica Dioica L.) Modulates Angiogenesis by Targeting the PI3K/AKT/eNOS Pathway in Prostate Cancer
Background: Medicinal plants, predominantly those rich in polyphenolic mixtures, have been recommended to have chemopreven...
The Safety and Efficacy of Cold Atmospheric Plasma as a Novel Therapy: An in vivo Study
Background: Cold atmospheric plasma (CAP) may reduce bacteria and aid wound healing through reactive oxygen species. Recen...
N-Nornuciferine Promotes Human Non-Small Cell Lung Cancer A549 Cells Apoptosis via miR-361-3p/TRAF2/JNK Axis
Background: N-Nornuciferine (N-NF) is an aporphine alkaloid in lotus leaf with a good resource for obtaining the biologica...
The Effect of Proton Pump Inhibitors on Metastatic Breast Cancer in Patients Treated with CDK4/6i
Background: This study aimed to assess the effect of proton pump inhibitors (PPIs) on hormone receptor-positive (HR+) and ...
Efficacy of Combined Bevacizumab and Angiotensin-Converting Enzyme Inhibitors or Angiotensin II type 1 Receptor Blockers in Metastatic Colorectal Cancer Patients
Background: Bevacizumab, used in the treatment of metastatic colorectal cancer (mCRC), has an angiogenesis inhibitory effe...
Stromal Cell-Derived Factor1 Genetic Variation at Locus 801 in Patients with Endometrial Cancer
Background: The gene's 3′ untranslated region of stromal cell-derived factor1 (SDF-1/ CXC chemokine ligand 12 (CXCL12...
Ozonated Aloe Vera Oil Accelerates Radiation Dermatitis Healing in Sprague Dawley Rats
Background: Radiation dermatitis is the most common side-effect of radiation therapy. The current daily therapy uses topic...
Management of HER2-Low Metastatic Breast Cancer: A Comprehensive Statement by an Expert Group from the Middle East and Africa Region
Approximately 50 to 67% of breast cancers (BCs), traditionally categorized as human epidermal growth factor receptor 2 (HE...
The Value of Serum Nestin in Monitoring the Effects of Surgery and Chemotherapy in Female Breast Cancer Patients: A Comparison with Serum CA15.3
Background: Traditional tumor markers such as cancer antigen 15.3 (CA15.3) and carcinoembryonic antigen (CEA) exhibit limi...
Molecular Characterization and Metastatic Gene Signatures Based on Targeted Cancer Treatment Modalities
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Evaluation of the Interchangeability of Cone Beam Computed Tomography and Catalyst for Patient Positioning in Radiotherapy for Head and Neck Cancer Patients
Background: This study aims to evaluate the interchangeability between cone beam computed tomography (CBCT) and the optica...
An Ensemble Deep Learning Model for the Detection and Classification of Breast Cancer
Background: Detecting breast cancer in its early stages remains a significant challenge in the present context and is a le...
Disseminated Metastasis after Resection of Sacrococcygeal Teratoma with Mucinous Adenocarcinoma: A Case Report
Mature teratoma is a common tumor that can undergo malignant transformation, either in ovarian or extragonadal sites. Whil...
Primary Extraskeletal Ewing Sarcoma of the Pancreas - A Case Report
Extraskeletal Ewing sarcomas (EES) is a rare, aggressive malignancy that typically affects adolescents or young adults, pr...
Sipple Syndrome: From Diagnosis to Management - A Case Report
Multiple endocrine neoplasia (MEN) is a rare inherited disease caused by multiple complex mutations in the RET gene. It is...
Prognostic Significance of Notch-4, SATB-2, and Glutaminase-1 in Colorectal Adenocarcinoma
Background: Neurogenic Locus Notch Homology 4 (Notch-4) is crucial in maintaining stem cells. Special AT-rich sequence-bin...
Vitamin D Serum Levels in Oral Lichen Planus and Oral Cancer Patients
Background: This study aimed to evaluate serum vitamin D levels in patients with oral lichen planus (OLP) and oral squamou...
Evaluation of Fis-1 and miR-484 Expression Levels in Tumor Tissue Samples and Healthy Tumor Margins in Lung Cancer
Background: MicroRNAs (miRNAs) regulate gene expression and various cellular activities. They also hold significant import...
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