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Toward Characterizing Lymphatic Vasculature in the Mammary Gland During Normal Development and Tumor-Associated Remodeling
Toward Characterizing Lymphatic Vasculature in the Mammary Gland During Normal Development and Tumor-Associated Remodeling
Lymphatic vasculature has been shown to promote metastatic spread of breast cancer. Lymphatic vasculature, which is made u...
Single-Cell Transcription Mapping of Murine and Human Mammary Organoids Responses to Female Hormones
Single-Cell Transcription Mapping of Murine and Human Mammary Organoids Responses to Female Hormones
During female adolescence and pregnancy, rising levels of hormones result in a cyclic source of signals that control the d...
Fast Ultrasound Scanning is a Rapid, Sensitive, Precise and Cost-Effective Method to Monitor Tumor Grafts in Mice
Fast Ultrasound Scanning is a Rapid, Sensitive, Precise and Cost-Effective Method to Monitor Tumor Grafts in Mice
In preclinical studies, accurate monitoring of tumor dynamics is crucial for understanding cancer biology and evaluating t...
Protocols for Co-Culture Phenotypic Assays with Breast Cancer Cells and THP-1-Derived Macrophages
Protocols for Co-Culture Phenotypic Assays with Breast Cancer Cells and THP-1-Derived Macrophages
Tumor mass comprises not only cancer cells but also heterogeneous populations of immune and stromal cells, along with the ...
Spatial Engineering of Mammary Epithelial Cell Cultures with 3D Bioprinting Reveals Growth Control by Branch Point Proximity
Spatial Engineering of Mammary Epithelial Cell Cultures with 3D Bioprinting Reveals Growth Control by Branch Point Proximity
The three-dimensional (3D) structure of the ductal epithelium and the surrounding extracellular matrix (ECM) are integral ...
Single-cell Analysis Reveals Inter- and Intratumour Heterogeneity in Metastatic Breast Cancer
Single-cell Analysis Reveals Inter- and Intratumour Heterogeneity in Metastatic Breast Cancer
Metastasis is the leading cause of cancer-related deaths of breast cancer patients. Some cancer cells in a tumour go throu...
TGFß1 Stimulates Lymphatic Endothelial Cells to Produce IL7 and IL15, Which Act as Chemotactic Factors for Breast Cancer Cells with Mesenchymal Properties
TGFß1 Stimulates Lymphatic Endothelial Cells to Produce IL7 and IL15, Which Act as Chemotactic Factors for Breast Cancer Cells with Mesenchymal Properties
The lymphatic system is a major gateway for tumor cell dissemination but the mechanisms of how tumor cells gain access to ...
A molecular toolbox to study progesterone receptor signaling
A molecular toolbox to study progesterone receptor signaling
Progesterone receptor (PR) signaling is required for mammary gland development and homeostasis. A major bottleneck in stud...
High-fat diet, but not duration of lactation, increases mammary gland lymphatic vessel function and subsequent growth of inflammatory breast cancer cells
High-fat diet, but not duration of lactation, increases mammary gland lymphatic vessel function and subsequent growth of inflammatory breast cancer cells
Inflammatory breast cancer (IBC) presents as rapid-onset swelling and breast skin changes caused by tumor emboli in the br...
Fourteenth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer
Fourteenth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer
The fourteenth annual workshop of the European Network for Breast Development and Cancer (ENBDC) on Methods in Mammary Gla...
RETRACTED ARTICLE: Pure Primary Squamous Cell Carcinoma of the Breast Arising from the Epithelium of a Complex Mammary Cyst: A Case Report
RETRACTED ARTICLE: Pure Primary Squamous Cell Carcinoma of the Breast Arising from the Epithelium of a Complex Mammary Cyst: A Case Report
The Editor-in-Chief has retracted this article because it was published in error before peer review, and because of concer...
Distinct Requirements for Adaptor Proteins NCK1 and NCK2 in Mammary Gland Development
Distinct Requirements for Adaptor Proteins NCK1 and NCK2 in Mammary Gland Development
The adaptor proteins NCK1 and NCK2 are well-established signalling nodes that regulate diverse biological processes includ...
Non-Linear Lymphatic Anatomy in Breast Cancer Patients Prior to Axillary Lymph Node Dissection: A Risk Factor For Lymphedema Development
Non-Linear Lymphatic Anatomy in Breast Cancer Patients Prior to Axillary Lymph Node Dissection: A Risk Factor For Lymphedema Development
Immediate lymphatic reconstruction (ILR) at the time of axillary lymph node dissection (ALND) has become increasingly util...
Studying Mammary Physiology and Pathology in Domestic Species Benefits Both Humans and Animals
Studying Mammary Physiology and Pathology in Domestic Species Benefits Both Humans and Animals
In 2010 the worldwide population of domesticated ruminants was estimated to be 3.6 bi...
Gestational Breast Cancer – a Review of Outcomes, Pathophysiology, and Model Systems
Gestational Breast Cancer – a Review of Outcomes, Pathophysiology, and Model Systems
The onset of pregnancy marks the start of offspring development, and represents the key physiological event that induces r...
Imagine beyond: recent breakthroughs and next challenges in mammary gland biology and breast cancer research
Imagine beyond: recent breakthroughs and next challenges in mammary gland biology and breast cancer research
On 8 December 2022 the organizing committee of the European Network for Breast Development and Cancer labs (ENBDC) held it...
SFRP1 Expression is Inversely Associated With Metastasis Formation in Canine Mammary Tumours
SFRP1 Expression is Inversely Associated With Metastasis Formation in Canine Mammary Tumours
Canine mammary tumours (CMTs) are the most frequent tumours in intact female dogs and show strong similarities with human ...
Deciphering Stromal Changes between Metastatic and Non-metastatic Canine Mammary Carcinomas
Deciphering Stromal Changes between Metastatic and Non-metastatic Canine Mammary Carcinomas
Cancer-associated stroma (CAS) is widely recognized to influence development and progression of epithelial tumours includi...
PI3K inhibition circumvents resistance to SHP2 blockade in metastatic triple-negative breast cancer
PI3K inhibition circumvents resistance to SHP2 blockade in metastatic triple-negative breast cancer
The protein tyrosine phosphatase SHP2 activates oncogenic pathways downstream of most receptor tyrosine kinases (RTK) and ...
Molecular Characterization and Landscape of Breast cancer Models from a multi-omics Perspective
Molecular Characterization and Landscape of Breast cancer Models from a multi-omics Perspective
Breast cancer is well-known to be a highly heterogenous disease. This facet of cancer makes finding a research model that ...
Longitudinal analysis of bovine mammary gland development
Longitudinal analysis of bovine mammary gland development
Many studies on bovine mammary glands focus on one stage of development. Often missing in those studies are repeated measu...
ERBB Receptors and Their Ligands in the Developing Mammary Glands of Different Species: Fifteen Characters in Search of an Author
ERBB Receptors and Their Ligands in the Developing Mammary Glands of Different Species: Fifteen Characters in Search of an Author
The ERBB tyrosine kinase receptors and their ligands belong to a complex family that has diverse biological effects and ex...
FGFR2 Controls Growth, Adhesion and Migration of Nontumorigenic Human Mammary Epithelial Cells by Regulation of Integrin β1 Degradation
FGFR2 Controls Growth, Adhesion and Migration of Nontumorigenic Human Mammary Epithelial Cells by Regulation of Integrin β1 Degradation
The role of fibroblast growth factor receptor 2 (FGFR2), an important mediator of stromal paracrine and autocrine signals,...
Culture Models to Investigate Mechanisms of Milk Production and Blood-Milk Barrier in Mammary Epithelial Cells: a Review and a Protocol
Culture Models to Investigate Mechanisms of Milk Production and Blood-Milk Barrier in Mammary Epithelial Cells: a Review and a Protocol
Mammary epithelial cells (MECs) are the only cell type that produces milk during lactation. MECs also form less-permeable ...
The Serotonergic System and Bone Metabolism During Pregnancy and Lactation and the Implications of SSRI Use on the Maternal-Offspring Dyad
The Serotonergic System and Bone Metabolism During Pregnancy and Lactation and the Implications of SSRI Use on the Maternal-Offspring Dyad
Lactation is a physiological adaptation of the class Mammalia and is a product of over 200 million years of evolu...
Associations Between Dog Breed and Clinical Features of Mammary Epithelial Neoplasia in Bitches: an Epidemiological Study of Submissions to a Single Diagnostic Pathology Centre Between 2008–2021
Associations Between Dog Breed and Clinical Features of Mammary Epithelial Neoplasia in Bitches: an Epidemiological Study of Submissions to a Single Diagnostic Pathology Centre Between 2008–2021
Mammary cancer is one of the most common neoplasms of dogs, primarily bitches. While studies have been carried out identif...
Correction to: Rank ectopic expression in the presence of Neu and PyMT oncogenes alters mammary epithelial cell populations and their tumorigenic potential
Correction to: Rank ectopic expression in the presence of Neu and PyMT oncogenes alters mammary epithelial cell populations and their tumorigenic potential
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whic...
Correction to: Valine Treatment Enhances Antimicrobial Component Production in Mammary Epithelial Cells and the Milk of Lactating Goats Without Influencing the Tight Junction Barrier
Correction to: Valine Treatment Enhances Antimicrobial Component Production in Mammary Epithelial Cells and the Milk of Lactating Goats Without Influencing the Tight Junction Barrier
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whic...
Rank ectopic expression in the presence of Neu and PyMT oncogenes alters mammary epithelial cell populations and their tumorigenic potential
Rank ectopic expression in the presence of Neu and PyMT oncogenes alters mammary epithelial cell populations and their tumorigenic potential
Determination of the mammary epithelial cell that serves as the cell of origin for breast cancer is key to understand tumo...
Rank ectopic expression in the presence of Neu and MMTV oncogenes alters mammary epithelial cell populations and their tumorigenic potential
Rank ectopic expression in the presence of Neu and MMTV oncogenes alters mammary epithelial cell populations and their tumorigenic potential
Determination of the mammary epithelial cell that serves as the cell of origin for breast cancer is key to understand tumo...
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