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Acquired vulnerability against EGF receptor inhibition in gastric cancer promoted by class I histone deacetylase inhibitor entinostat
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True cancer stem cells exhibit relative degrees of dormancy and genomic stability
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Pancreatic cancer cells infiltrate nerves through TGFbeta1-driven perineural epithelial-to-mesenchymal-like transdifferentiation
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The chemokine CX3CL1 promotes intraperitoneal tumour growth despite enhanced T-cell recruitment in ovarian cancer
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Therapeutic benefit of the dual ALK/FAK inhibitor ESK440 in ALK-driven neuroblastoma
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Microbial molecules, metabolites, and malignancy
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Cancer stem-like cells stay in a plastic state ready for tumor evolution
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SLC31A1 promotes chemoresistance through inducing CPT1A-mediated fatty acid oxidation in ER-positive breast cancer
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ZC3H15 suppression ameliorates bone cancer pain through inhibiting neuronal oxidative stress and microglial inflammation
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YPEL2 regulates the efficacy of BRD4-EZH2 dual targeting in EZH2Y641mut germinal center-derived lymphoma
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The Impact of Atorvastatin on Intraprostatic Biomarkers – Prognostic Value of 3LS-score – Follow-up of ESTO1-Trial
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Disruption of redox balance in glutaminolytic triple negative breast cancer by inhibition of glutaminase and glutamate export
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MYH knockdown in pancreatic cancer cells creates an exploitable DNA repair vulnerability
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STAT signaling in the pathogenesis and therapy of acute myeloid leukemia and myelodysplastic syndromes
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Targeting of oncogenic AAA-ATPase TRIP13 reduces progression of pancreatic ductal adenocarcinoma
Targeting of oncogenic AAA-ATPase TRIP13 reduces progression of pancreatic ductal adenocarcinoma
KeywordsPancreatic ductal adenocarcinomaTRIP13Tumor progressionMetastasisImmune responseAbbreviationsEMTepithelial-mesench...
Evidence based on Mendelian randomization: Causal relationship between mitochondrial biological function and lung cancer and its subtypes
Evidence based on Mendelian randomization: Causal relationship between mitochondrial biological function and lung cancer and its subtypes
ObjectiveThis study aimed to investigate the causal relationship between mitochondrial biological function and lung cancer...
Hepatocellular loss of mTOR aggravates tumor burden in nonalcoholic steatohepatitis-related HCC
Hepatocellular loss of mTOR aggravates tumor burden in nonalcoholic steatohepatitis-related HCC
Obesity and associated nonalcoholic steatohepatitis (NASH) are on the rise globally. NASH became an important driver of he...
Acral melanoma: new insights into the immune and genomic landscape
Acral melanoma: new insights into the immune and genomic landscape
Volume 46, December 2023, 100947Author links open overlay panel, , , AbstractAcral melanoma is a rare subtype of melanoma ...
A sensitive and robust plasma-based DNA methylation panel for early detection of target gastrointestinal cancers
A sensitive and robust plasma-based DNA methylation panel for early detection of target gastrointestinal cancers
Volume 46, December 2023, 100941Author links open overlay panel, , , , , , , , , , , , , , , Highlights•A novel, cost-effe...
Patient recruitment into clinical studies of solid malignancies during the COVID-19 pandemic in a tertiary cancer center
Patient recruitment into clinical studies of solid malignancies during the COVID-19 pandemic in a tertiary cancer center
Volume 46, December 2023, 100946Author links open overlay panel, , , , , , , , , , , , , , , , Highlights•Assessment of cl...
Therapeutic targeting of tumor spheroids in a 3D microphysiological renal cell carcinoma-on-a-chip system
Therapeutic targeting of tumor spheroids in a 3D microphysiological renal cell carcinoma-on-a-chip system
Metastatic renal cell carcinoma (RCC) remains an incurable disease for most patients highlighting an urgent need for new t...
Mitochondrial adaptation decreases drug sensitivity of persistent triple negative breast cancer cells surviving combinatory and sequential chemotherapy
Mitochondrial adaptation decreases drug sensitivity of persistent triple negative breast cancer cells surviving combinatory and sequential chemotherapy
Volume 46, December 2023, 100949Author links open overlay panel, , , , , , , , , , AbstractTriple negative breast cancer (...
Innate immunity: Looking beyond T-cells in radiation and immunotherapy combinations
Innate immunity: Looking beyond T-cells in radiation and immunotherapy combinations
Volume 46, December 2023, 100940Author links open overlay panel, , , AbstractRadiation therapy is an established and effec...
Time-restricted feeding affects the fecal microbiome metabolome and its diurnal oscillations in lung cancer mice
Time-restricted feeding affects the fecal microbiome metabolome and its diurnal oscillations in lung cancer mice
Original raw data in this manuscript were deposited to Sequence Read Archive (SRA) database of NCBI (Accession number: SRP...