Generation of orthotopic intracranial glioblastoma patient-derived xenograft models: insights into extrachromosomal DNA-driven MYC(N) and PDGFRA oncogene amplification and preliminary therapeutic evaluation

Update your browser to view ScienceDirect correctly.

Your technical details and browser version:

Request ID: 9885c1269aa9ffb8-LAX IP: 118.31.43.22 UTC time: 2025-10-02T17:00:10+00:00 Browser: Mozilla/5.0 (X11; U; Linux x86_64; en-US; rv:1.9.1.4) Gecko/20091030 Gentoo Firefox/3.5.4