SCI Abstract

search
+
Suppression of breast cancer metastatic behavior by microRNAs targeting EMT transcription factors. A relevant participation of miR-196a-5p and miR-22-3p in ZEB1 expression
Suppression of breast cancer metastatic behavior by microRNAs targeting EMT transcription factors. A relevant participation of miR-196a-5p and miR-22-3p in ZEB1 expression
Metastasis, the leading cause of cancer-associated deaths, is promoted by transcription factors SNAIL, SLUG, ZEB1 and TWIS...
Predicting the likelihood of carrying or pathogenic variants in high-risk Pakistani breast cancer patients
Predicting the likelihood of carrying or pathogenic variants in high-risk Pakistani breast cancer patients
Pathogenic variants (PVs) in BRCA1/2 increase the lifetime risk of breast cancer (BC). Predictive algorithms for BRCA1/2 P...
Omission of multimodal therapy in older adults with high-risk breast cancer
Omission of multimodal therapy in older adults with high-risk breast cancer
Treatment guidelines recommend multimodal therapy for non-metastatic high-risk breast cancer in older adults. However, old...
Effect of chemotherapy timing in triple-negative breast cancer: a real-world evidence study
Effect of chemotherapy timing in triple-negative breast cancer: a real-world evidence study
Triple-negative breast cancer (TNBC) is an aggressive, heterogeneous malignancy with poor prognosis. The optimal timing of...
Invasive lobular breast carcinoma variants; clinicopathological features and patient outcomes
Invasive lobular breast carcinoma variants; clinicopathological features and patient outcomes
An understanding of the differences among the invasive lobular breast carcinoma (ILC) variants is crucial for risk stratif...
Management of ipsilateral breast tumor recurrence after prior breast conservation therapy
Management of ipsilateral breast tumor recurrence after prior breast conservation therapy
Mastectomy is traditionally recommended for local recurrence after breast conservation therapy (BCT), the combination of l...
Social determinants of cardiovascular disease in women with and without breast cancer
Social determinants of cardiovascular disease in women with and without breast cancer
Social determinants of health (SDOH) may impact cardiovascular (CV) risk in women with and without breast cancer (BC). In ...
Timely germline testing after invasive breast cancer promotes contralateral risk-reducing mastectomy and improves survival: an observational retrospective study
Timely germline testing after invasive breast cancer promotes contralateral risk-reducing mastectomy and improves survival: an observational retrospective study
To report the rates of risk-reducing surgery (RRS) following germline testing for BRCA1/2 (likely) pathogenic variants (BR...
Subtype-specific dysregulation of biogenic amine-related genes and miRNAs in breast cancer: identification of DRD2, HRH2, and HRH4 as potential therapeutic targets in TNBC and HER2+ subtypes
Subtype-specific dysregulation of biogenic amine-related genes and miRNAs in breast cancer: identification of DRD2, HRH2, and HRH4 as potential therapeutic targets in TNBC and HER2+ subtypes
Biogenic amines (BAs) are known to influence tumorigenesis, yet their precise role in breast cancer remains unclear. This ...
Breast magnetic resonance imaging patterns of tumor regression after neoadjuvant chemotherapy and immunotherapy in early triple-negative breast cancer patients: prediction of pathological response and performance of ultrafast sequences
Breast magnetic resonance imaging patterns of tumor regression after neoadjuvant chemotherapy and immunotherapy in early triple-negative breast cancer patients: prediction of pathological response and performance of ultrafast sequences
Immunotherapy with pembrolizumab combined with neoadjuvant chemotherapy allows an improvement of pathological complete res...
Metastatic breast cancer through the Oncotype DX Breast Recurrence Score®: insights from a small cohort study
Metastatic breast cancer through the Oncotype DX Breast Recurrence Score®: insights from a small cohort study
To evaluate the feasibility of obtaining a 21-gene Oncotype DX Breast Recurrence Score® (RS) result from metastatic b...
Exploring the Nottingham classification: assessing gene expression profiles in breast cancer patients and their association with outcomes
Exploring the Nottingham classification: assessing gene expression profiles in breast cancer patients and their association with outcomes
Breast cancer remains a major global health concern due to its high incidence and mortality among women. Accurate prognost...
Genomic and proteomic profiling of mutant metastatic hormone receptor-positive breast cancer and impact on clinical outcomes
Genomic and proteomic profiling of mutant metastatic hormone receptor-positive breast cancer and impact on clinical outcomes
GATA3 mutations are among the most common alterations in hormone receptor-positive (HR+) breast cancer (BC), yet these hav...
Breast imaging recommendations for young females (age < 40 years) with ≥ 20% lifetime breast cancer risk: practice patterns at a specialized clinic
Breast imaging recommendations for young females (age < 40 years) with ≥ 20% lifetime breast cancer risk: practice patterns at a specialized clinic
The National Comprehensive Cancer Network (NCCN) and American Cancer Society (ACS) endorse differing guidelines for screen...
National trends in neoadjuvant systemic therapy utilization in patients with early-stage HER2-positive breast cancer from 2016–2021: The impact of the KATHERINE trial
National trends in neoadjuvant systemic therapy utilization in patients with early-stage HER2-positive breast cancer from 2016–2021: The impact of the KATHERINE trial
Neoadjuvant systemic therapy (NST) for HER2 + breast cancer (HER2 + BC) has historically been used...
Insurer and patient costs for repeat breast surgery after initial lumpectomy for breast cancer
Insurer and patient costs for repeat breast surgery after initial lumpectomy for breast cancer
 ~ 14–25% of patients who undergo a primary lumpectomy for the treatment of breast cancer require a reop...
The effects of contemporary treatment of DCIS on the risk of developing an ipsilateral invasive Breast cancer (iIBC) in the Dutch population
The effects of contemporary treatment of DCIS on the risk of developing an ipsilateral invasive Breast cancer (iIBC) in the Dutch population
To assess the effects of contemporary treatment of ductal carcinoma in situ (DCIS) on the risk of developing an ipsilatera...
Optimizing surgical strategy in locally advanced breast cancer: a comparative analysis between preoperative MRI and postoperative pathology after neoadjuvant chemotherapy
Optimizing surgical strategy in locally advanced breast cancer: a comparative analysis between preoperative MRI and postoperative pathology after neoadjuvant chemotherapy
In the treatment of breast cancer, neo-adjuvant chemotherapy is often used as systemic treatment followed by tumor excisio...
Association of physical weight statuses defined by body mass index (BMI) with molecular subtypes of premenopausal breast cancer: a systematic review and meta-analysis
Association of physical weight statuses defined by body mass index (BMI) with molecular subtypes of premenopausal breast cancer: a systematic review and meta-analysis
The association between overweight/obesity and postmenopausal breast cancer has been proven. However, uncertainty exists r...
Unveiling the HER2-low phenomenon: exploring immunohistochemistry and gene expression to characterise HR-positive HER2-negative early breast cancer
Unveiling the HER2-low phenomenon: exploring immunohistochemistry and gene expression to characterise HR-positive HER2-negative early breast cancer
HER2-low breast cancer (BC) is a novel entity with relevant therapeutic implications, especially in hormone receptor (HR) ...
Secretory breast carcinoma: clinicopathological features and prognosis of 52 patients
Secretory breast carcinoma: clinicopathological features and prognosis of 52 patients
Secretory breast carcinoma is a rare histological subtype of invasive breast cancer and considered with an indolent clinic...
A randomized phase II study of metronomic cyclophosphamide and methotrexate (CM) with or without bevacizumab in patients with advanced breast cancer
A randomized phase II study of metronomic cyclophosphamide and methotrexate (CM) with or without bevacizumab in patients with advanced breast cancer
Metronomic chemotherapy has the potential to offer tumor control with reduced toxicity when compared to standard dose chem...
A new methodology to predict the oncotype scores based on clinico-pathological data with similar tumor profiles
A new methodology to predict the oncotype scores based on clinico-pathological data with similar tumor profiles
The Oncotype DX (ODX) test is a commercially available molecular test for breast cancer assay that provides prognostic and...
Biomarkers predictive of a response to extended endocrine therapy in breast cancer: a systematic review and meta-analysis
Biomarkers predictive of a response to extended endocrine therapy in breast cancer: a systematic review and meta-analysis
Extension of adjuvant endocrine therapy beyond five years confers only modest survival benefit in breast cancer patients a...
The role of endocrine treatment on the risk of developing an ipsilateral invasive breast cancer in hormone receptor positive patients with ductal carcinoma in situ
The role of endocrine treatment on the risk of developing an ipsilateral invasive breast cancer in hormone receptor positive patients with ductal carcinoma in situ
Conflict of interest We declare that I have no conflict of interest...
Presence of crown-like structures in breast adipose tissue; differences between healthy controls, BRCA1/2 gene mutation carriers and breast cancer patients
Presence of crown-like structures in breast adipose tissue; differences between healthy controls, BRCA1/2 gene mutation carriers and breast cancer patients
Crown-like structures (CLS) in breast adipose tissue are associated with inflammation and a potential factor in breast can...
Northern origin of the BRCA2 c.5286 T > G founder allele
Northern origin of the BRCA2 c.5286 T > G founder allele
Conflict of interest The authors declare no conflicts of interest. ...
Association between prediabetes and breast cancer: a comprehensive meta-analysis
Association between prediabetes and breast cancer: a comprehensive meta-analysis
Breast cancer accounts for up to 30% of cancer cases in women in the US. Diabetes mellitus has been recognized as a risk f...
Randomized adaptive selection trial of cryotherapy, compression therapy, and placebo to prevent taxane-induced peripheral neuropathy in patients with breast cancer
Randomized adaptive selection trial of cryotherapy, compression therapy, and placebo to prevent taxane-induced peripheral neuropathy in patients with breast cancer
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating adverse effect of taxane therapy. Small non...
Restoring microRNA-34a overcomes acquired drug resistance and disease progression in human breast cancer cell lines via suppressing the ABCC1 gene
Restoring microRNA-34a overcomes acquired drug resistance and disease progression in human breast cancer cell lines via suppressing the ABCC1 gene
Breast cancer is one of the leading types of cancer diagnosed in women. Despite the improvements in chemotherapeutic cure ...
Load More
format_indent_increase