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Health economic evaluation of Mirvetuximab soravtansine for the treatment of FRα-positive, platinum resistant ovarian cancer in Germany
Health economic evaluation of Mirvetuximab soravtansine for the treatment of FRα-positive, platinum resistant ovarian cancer in Germany
Mirvetuximab soravtansine (MIRV) is an antibody–drug conjugate targeting the folate receptor α (FRα), appr...
Correlation of preoperative radiological lymph node assessment with pathological nodal and tumor findings in tongue and oral floor squamous cell carcinoma
Correlation of preoperative radiological lymph node assessment with pathological nodal and tumor findings in tongue and oral floor squamous cell carcinoma
Preoperative imaging is central to cervical lymph node staging in oral squamous cell carcinoma (OSCC). However, the pathol...
Years of life lost in cutaneous squamous cell carcinoma: analysis of a prospective cohort of 1400 patients
Years of life lost in cutaneous squamous cell carcinoma: analysis of a prospective cohort of 1400 patients
Cutaneous squamous cell carcinoma (cSCC) occurs predominantly in older adults. Disease-specific mortality is low, but conv...
Diagnostic performance and clinical limitations of sentinel lymph node biopsy in head and neck melanoma: a 20-year retrospective cohort study
Diagnostic performance and clinical limitations of sentinel lymph node biopsy in head and neck melanoma: a 20-year retrospective cohort study
Sentinel lymph node biopsy (SLNB) is a standard procedure for nodal staging in cutaneous melanoma. However, its diagnostic...
Residential radon exposure and lung cancer histology and stage: a population-based ecological study in Central Germany
Residential radon exposure and lung cancer histology and stage: a population-based ecological study in Central Germany
Residential radon exposure is recognised as one of the leading environmental risk factors for lung cancer and acts synergi...
Investigation of a GPC1-targeted and LIFU-responsive nanoplatform with ADV effect for visualized chemo-sonodynamic therapy against pancreatic ductal adenocarcinoma
Investigation of a GPC1-targeted and LIFU-responsive nanoplatform with ADV effect for visualized chemo-sonodynamic therapy against pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies. Regardless of surgical resection, che...
Photon counting computed tomography in head and neck squamous cell carcinoma: iodine concentration and histopathological features
Photon counting computed tomography in head and neck squamous cell carcinoma: iodine concentration and histopathological features
Head and neck squamous cell carcinoma (HNSCC) is a common malignancy with increasing relevance in oncologic imaging. Photo...
-amplified NSCLC treated with savolitinib achieved remarkable tumor regression: a case report and review of literature
-amplified NSCLC treated with savolitinib achieved remarkable tumor regression: a case report and review of literature
Primary MET amplification is an infrequent tumorigenic driver gene alteration identified in pulmonary neoplasms. Data on t...
Patterns and outcomes of current antitumor therapy for high-grade neuroendocrine neoplasms: perspective of a tertiary referral center
Patterns and outcomes of current antitumor therapy for high-grade neuroendocrine neoplasms: perspective of a tertiary referral center
Patients with metastatic high-grade neuroendocrine neoplasms (NEN) have an unfavorable prognosis. Treatment patterns and t...
Artificial intelligence algorithm for preoperative prediction of FIGO stage in ovarian cancer based on clinical features integrated 18F-FDG PET/CT metabolic and radiomics features
Artificial intelligence algorithm for preoperative prediction of FIGO stage in ovarian cancer based on clinical features integrated 18F-FDG PET/CT metabolic and radiomics features
The International Federation of Gynecology and Obstetric (FIGO) stage is critical to guiding the treatments of ovarian can...
Effect of the COVID-19 pandemic and lockdown on cancer stage distribution and time to treatment initiation using cancer registry data of the Swiss cantons of Zurich and Zug from 2018 to 2021
Effect of the COVID-19 pandemic and lockdown on cancer stage distribution and time to treatment initiation using cancer registry data of the Swiss cantons of Zurich and Zug from 2018 to 2021
Swiss healthcare institutions conducted only urgent procedures during the COVID-19 lockdown, potentially leading to a lack...
Docetaxel rechallenge in HER2-negative metastatic breast cancer: a real-world study of previously discontinued patients for non-progression reasons
Docetaxel rechallenge in HER2-negative metastatic breast cancer: a real-world study of previously discontinued patients for non-progression reasons
This study aimed to evaluate the efficacy and safety of docetaxel rechallenge in HER2-negative metastatic breast cancer (M...
Cyclosporine plus methotrexate versus cyclosporine alone for graft-versus-host disease prophylaxis in pediatric patients undergoing hematopoietic stem cell transplantation from an HLA-identical sibling
Cyclosporine plus methotrexate versus cyclosporine alone for graft-versus-host disease prophylaxis in pediatric patients undergoing hematopoietic stem cell transplantation from an HLA-identical sibling
The use of antimetabolite in Graft-versus-Host Disease (GvHD) prophylaxis after bone ...
Gd-DOTA-PSMA as theranostic bio-gadolinium agent for prostate cancer targeted gadolinium neutron capture therapy
Gd-DOTA-PSMA as theranostic bio-gadolinium agent for prostate cancer targeted gadolinium neutron capture therapy
Gadolinium-neutron capture therapy (Gd-NCT) employs isotopically enriched Gadolinium (Gd) and thermal neutrons to selectiv...
Prognostic value of folate-associated gene expression in stage II colon cancer
Prognostic value of folate-associated gene expression in stage II colon cancer
Prognostic variability in stage II colon cancer underscores the need for better risk stratification. Analyzing folate-asso...
Pan-cancer analysis to character the clinicopathological and genomic features of KRAS-mutated patients in China
Pan-cancer analysis to character the clinicopathological and genomic features of KRAS-mutated patients in China
The Kirsten rat sarcoma viral oncogene (KRAS) is the most frequently mutated oncogene in human cancers. Significant advanc...
Sex-related disparities in outcomes of survival in biliary tract cancer patients
Sex-related disparities in outcomes of survival in biliary tract cancer patients
Biliary tract cancer (BTC) is a rare and aggressive cancer with a poor prognosis. Despite treatment, overall survival is l...
CENPF as a prognostic marker of glioma: unraveling the molecular mechanisms
CENPF as a prognostic marker of glioma: unraveling the molecular mechanisms
Glioma is the dominant primary intracranial malignancy. The roles of CENPF and the CENPF - p53 axis in glioma remain elusi...
Analysis of prognosis and related influencing factors of different surgical approaches for early cervical cancer
Analysis of prognosis and related influencing factors of different surgical approaches for early cervical cancer
To evaluate the 5-year survival rates of patients with early cervical cancer (CC) under different surgical approaches and ...
Long-term results of locoregionally advanced nasopharyngeal carcinoma treated with cisplatin and 5-fluorouracil induction chemotherapy with or without docetaxel in young and middle aged adults
Long-term results of locoregionally advanced nasopharyngeal carcinoma treated with cisplatin and 5-fluorouracil induction chemotherapy with or without docetaxel in young and middle aged adults
This study aims to evaluate the efficacy and toxicity of the two induction chemotherapy (IC) regimens (TPF: docetaxel, cis...
LncRNA LINC01128 promotes prostate cancer cell proliferation, metastasis, and epithelial-mesenchymal transition by modulating miR-27b-3p
LncRNA LINC01128 promotes prostate cancer cell proliferation, metastasis, and epithelial-mesenchymal transition by modulating miR-27b-3p
Prostate cancer (PCa) is a prevalent malignancy within the male reproductive system that poses a significant threat to pat...
Real-world treatment patterns and clinical outcomes in patients with locally advanced or metastatic urothelial carcinoma in Germany: retrospective CONVINCE study
Real-world treatment patterns and clinical outcomes in patients with locally advanced or metastatic urothelial carcinoma in Germany: retrospective CONVINCE study
CONVINCE is a retrospective medical chart review study that examined demographics, treatment patterns, and outcomes in pat...
The screening value of mammography for breast cancer: an overview of 28 systematic reviews with evidence mapping
The screening value of mammography for breast cancer: an overview of 28 systematic reviews with evidence mapping
The effectiveness of mammography screening in reducing breast cancer mortality and the accuracy of various mammography tec...
Impact of interdisciplinary tumor boards (ITB) and personalized treatment on survival outcomes in metastatic castration-resistant prostate cancer
Impact of interdisciplinary tumor boards (ITB) and personalized treatment on survival outcomes in metastatic castration-resistant prostate cancer
Interdisciplinary tumor boards (ITB) are essential in optimizing treatment recommendations for metastatic castration-resis...
Semaglutide, a glucagon-like peptide-1 receptor agonist, inhibits oral squamous cell carcinoma growth through P38 MAPK signaling pathway
Semaglutide, a glucagon-like peptide-1 receptor agonist, inhibits oral squamous cell carcinoma growth through P38 MAPK signaling pathway
Researches have shown that diabetes mellitus (DM) can promote the risk and progression of oral squamous cell carcinoma (OS...
Breast cancer prediction using different machine learning methods applying multi factors
Breast cancer prediction using different machine learning methods applying multi factors
Breast cancer (BC) is a multifactorial disease and is one of the most common cancers globally. This study aimed to compare...
Emerging markers of cancer cachexia and their relationship to sarcopenia
Emerging markers of cancer cachexia and their relationship to sarcopenia
Emerging biomarkers of cancer cachexia and their roles in sarcopenia and prognosis are poorly understood. Baseline assessm...
Herpes zoster is not associated with subsequent gastrointestinal cancer: data from over 200,000 outpatients in Germany
Herpes zoster is not associated with subsequent gastrointestinal cancer: data from over 200,000 outpatients in Germany
Gastrointestinal (GI) cancers are an increasing global health challenge. Viral diseases play an important role in the deve...
The value of an apparent diffusion coefficient histogram model in predicting meningioma recurrence
The value of an apparent diffusion coefficient histogram model in predicting meningioma recurrence
To investigate the predictive value of a model combining conventional MRI features and apparent diffusion coefficient (ADC...
Identification of SAA1 as a novel metastasis marker in ovarian cancer and development of a graphene-based detection platform for early assessment
Identification of SAA1 as a novel metastasis marker in ovarian cancer and development of a graphene-based detection platform for early assessment
Ovarian cancer (OC) is a prevalent gynecological malignancy with the highest mortality rate, which generally diagnosed at ...
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