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Mechanism of crosstalk between Helicobacter pylori and immune stromal cells in the development and occurrence of gastric cancer
Mechanism of crosstalk between Helicobacter pylori and immune stromal cells in the development and occurrence of gastric cancer
Helicobacter pylori (Hp) has been classified as a class I carcinogen in gastric cancer, and one of the important mechanism...
Disease burden and trends of bladder cancer in the world and BRICS from 1990 to 2021 and its projection until 2036: analysis based on the global burden of disease study 2021
Disease burden and trends of bladder cancer in the world and BRICS from 1990 to 2021 and its projection until 2036: analysis based on the global burden of disease study 2021
The rising burden of bladder cancer (BCa) calls for in-depth research. This study, based on Global Burden of Disease (GBD)...
RAD51 modulates in nasopharyngeal carcinoma cells by regulating Caspase-8-mediated pyroptosis
RAD51 modulates in nasopharyngeal carcinoma cells by regulating Caspase-8-mediated pyroptosis
Radiotherapy is a first-line treatment for nasopharyngeal carcinoma (NPC), but resistance to radiation remains a major cli...
Integrative genomic analysis identifies novel causal genes of Hodgkin’s and non-Hodgkin’s lymphoma
Integrative genomic analysis identifies novel causal genes of Hodgkin’s and non-Hodgkin’s lymphoma
The genetic mechanisms underlying non-Hodgkin lymphoma (NHL) and Hodgkin lymphoma (HL) remain understudied. While numerous...
Integrating bulk and single-cell RNA sequencing reveals intratumor heterogeneity phenotypes and immune infiltration in pancreatic cancer
Integrating bulk and single-cell RNA sequencing reveals intratumor heterogeneity phenotypes and immune infiltration in pancreatic cancer
Although the significance of intratumoral heterogeneity (ITH) has been widely acknowledged in various cancers, its role in...
Machine learning modeling and analysis of prognostic hub genes in cervical adenocarcinoma: a multi target therapy for enhancement in immunosurveillance
Machine learning modeling and analysis of prognostic hub genes in cervical adenocarcinoma: a multi target therapy for enhancement in immunosurveillance
Endocervical adenocarcinoma (ECA) the fatal and intrusive subtype of cervical carcinoma is on rise from the last decade. I...
Pathological omics prediction of early and advanced colon cancer based on artificial intelligence model
Pathological omics prediction of early and advanced colon cancer based on artificial intelligence model
Artificial intelligence (AI) models based on pathological slides have great potential to assist pathologists in disease di...
GALNT6 associated with O-GlcNAcylation contributes to the tumorigenesis of oral squamous cell carcinoma
GALNT6 associated with O-GlcNAcylation contributes to the tumorigenesis of oral squamous cell carcinoma
We aimed to explore the regulatory gene associated with O-GlcNAcylation in oral squamous cell carcinoma (OSCC) and the und...
Dexamethasone, celecoxib, and simvastatin-induced 5-fluorouracil resistance in cancer cells: a possible role of lipid droplet accumulation
Dexamethasone, celecoxib, and simvastatin-induced 5-fluorouracil resistance in cancer cells: a possible role of lipid droplet accumulation
This study investigates the impact of dexamethasone (DEX), celecoxib (CXB), and simvastatin (SMV) on 5-fluorouracil (5-FU)...
Causal association between modifiable risk factors and esophageal cancer: A Mendelian randomization study
Causal association between modifiable risk factors and esophageal cancer: A Mendelian randomization study
Esophageal cancer (EC), recognized for its aggressive nature, ranks as the sixth leading cause of cancer-associated mortal...
Nodal metastasis in surgically treated sinonasal squamous cell carcinoma
Nodal metastasis in surgically treated sinonasal squamous cell carcinoma
Tumor factors such as subsite and stage impact the risk of lymph node metastasis (LNM) and overall risk in sinonasal squam...
Altered glycosylation of EVs in cancers: galectin-3-binding protein (LGALS3BP)
Altered glycosylation of EVs in cancers: galectin-3-binding protein (LGALS3BP)
Extracellular vesicles (EVs) are membrane-bound structures secreted by various cell types, acting as carriers of complex c...
Pan-cancer analysis and experimental validation revealed the prognostic role of ZNF83 in renal and lung cancer cohorts
Pan-cancer analysis and experimental validation revealed the prognostic role of ZNF83 in renal and lung cancer cohorts
Abnormal expression of zinc finger (ZNF) proteins is closely associated with tumor proliferation and metastasis. However, ...
In silico analysis of the oncogenic role of myoferlin (MYOF) and suggestion of folate as a potential therapeutic for brain cancer in the Caucasian population
In silico analysis of the oncogenic role of myoferlin (MYOF) and suggestion of folate as a potential therapeutic for brain cancer in the Caucasian population
Myoferlin (MYOF), a key gene in endocytosis, is known to be crucial for metastasis in cancer. While the involvement of MYO...
A machine learning-based screening model for the early detection of prostate cancer developed using serum microRNA data from a mixed cohort of 8,741 participants
A machine learning-based screening model for the early detection of prostate cancer developed using serum microRNA data from a mixed cohort of 8,741 participants
Early detection of prostate cancer (PCa) can improve the prognosis of patients. Currently, the role of the prostate specif...
Comparison of differences in hematogenous metastasis among cervical cancer patients by CT-guided three-tube intracavitary brachytherapy and hybrid intracavitary and interstitial brachytherapy
Comparison of differences in hematogenous metastasis among cervical cancer patients by CT-guided three-tube intracavitary brachytherapy and hybrid intracavitary and interstitial brachytherapy
To compare whether CT-guided three-tube intracavitary brachytherapy (ICBT) and hybrid intracavitary with interstitial brac...
The role of long noncoding RNA SNHG29 in malignant tumors
The role of long noncoding RNA SNHG29 in malignant tumors
Long noncoding RNAs (lncRNAs), defined as noncoding transcripts exceeding 200 nucleotides without protein-coding potential...
Evaluating the efficacy of mind maps and micro-videos in postoperative care education for lung cancer patients
Evaluating the efficacy of mind maps and micro-videos in postoperative care education for lung cancer patients
Early health education is crucial for lung cancer patients and their families to learn self-monitoring and how to seek app...
A rare case of HER2-positive pure metaplastic squamous cell carcinoma of the breast
A rare case of HER2-positive pure metaplastic squamous cell carcinoma of the breast
Primary squamous cell carcinoma of the breast (PSCCB) is a rare form of metaplastic breast carcinoma (MpBC), constituting ...
Comprehensive analysis of DNA methylation gene expression profiles in GEO dataset reveals biomarkers related to malignant transformation of sinonasal inverted papilloma
Comprehensive analysis of DNA methylation gene expression profiles in GEO dataset reveals biomarkers related to malignant transformation of sinonasal inverted papilloma
DNA methylation may be involved in the regulation of malignant transformation from sinonasal inverted papilloma (SNIP) to ...
Effects of different surgical approaches on health-related quality of life in pediatric and adolescent patients with papillary thyroid carcinoma
Effects of different surgical approaches on health-related quality of life in pediatric and adolescent patients with papillary thyroid carcinoma
We aimed to compare the health-related quality of life (HRQOL) in pediatric and adolescent patients with papillary thyroid...
Comprehensive analysis of T cell exhaustion related signature for predicting prognosis and immunotherapy response in HNSCC
Comprehensive analysis of T cell exhaustion related signature for predicting prognosis and immunotherapy response in HNSCC
T cell exhaustion (TEX) signifies a condition of T cell disorder which implicate the therapeutic benefits and prognostic s...
The prognostic value of LAYN in HPV-related head and neck squamous cell carcinoma and its influence on immune cell infiltration
The prognostic value of LAYN in HPV-related head and neck squamous cell carcinoma and its influence on immune cell infiltration
HPV-positive head and neck squamous cell carcinoma (HNSCC) exhibits different characteristics from HPV-negative tumors in ...
The prevalence of ADSL (rs3788579) and CYP1A2 (rs17861162) polymorphisms in female breast cancer patients in North-West Iran
The prevalence of ADSL (rs3788579) and CYP1A2 (rs17861162) polymorphisms in female breast cancer patients in North-West Iran
Breast cancer is a prevalent and significant contributor to cancer-related mortality among women worldwide. Its increasing...
Causal relationship between gut microbiota and prostate cancer contributes to the gut-prostate axis: insights from a Mendelian randomization study
Causal relationship between gut microbiota and prostate cancer contributes to the gut-prostate axis: insights from a Mendelian randomization study
Changes in gut microbiota abundance have been linked to prostate cancer development. However, the causality of the gut-pro...
Low serum total cholesterol levels predict inferior prognosis of patients with POEMS syndrome
Low serum total cholesterol levels predict inferior prognosis of patients with POEMS syndrome
Low serum cholesterol levels are associated with increased tumor morbidity and mortality. However, the relationship betwee...
Identification and validation of a novel six-gene signature based on mucinous adenocarcinoma-related gene molecular typing in colorectal cancer
Identification and validation of a novel six-gene signature based on mucinous adenocarcinoma-related gene molecular typing in colorectal cancer
Colorectal mucinous adenocarcinoma (MAC) is a particular pathological type that has yet to be thoroughly studied. This stu...
Unveiling NUSAP1 as a common gene signature linking chronic HBV infection and HBV-related HCC
Unveiling NUSAP1 as a common gene signature linking chronic HBV infection and HBV-related HCC
Hepatitis B virus (HBV) is a significant contributor to the development of hepatocellular carcinoma (HCC). Chronic HBV inf...
The impact of radiomics in the management of soft tissue sarcoma
The impact of radiomics in the management of soft tissue sarcoma
Soft tissue sarcomas (STSs) are rare malignancies. Pre-therapeutic tumour grading and assessment are crucial in making tre...
SAA1 regulated by S1P/S1PR1 promotes the progression of ESCC via β-catenin activation
SAA1 regulated by S1P/S1PR1 promotes the progression of ESCC via β-catenin activation
Serum amyloid A1 (SAA1), an inflammation-related molecule, is associated with the malignant progression of many tumors. Th...
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