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Emerging Therapeutic Approaches to Pancreatic Adenocarcinoma: Advances and Future Directions
Emerging Therapeutic Approaches to Pancreatic Adenocarcinoma: Advances and Future Directions
Pancreatic adenocarcinoma remains a leading cause of cancer-related mortality worldwide. Although surgery can be curable f...
From Fallopian Tube to Ovarian Cancer: Understanding the Evaluation and Management of Serous Tubal Intraepithelial Carcinoma Lesions
From Fallopian Tube to Ovarian Cancer: Understanding the Evaluation and Management of Serous Tubal Intraepithelial Carcinoma Lesions
Ovarian cancer, particularly high-grade serous carcinoma (HGSC), remains a leading cause of mortality in gynecologic oncol...
Care of Older Adults with Acute Myeloid Leukemia: The Role of Geriatric Assessment
Care of Older Adults with Acute Myeloid Leukemia: The Role of Geriatric Assessment
Older adults with acute myeloid leukemia (AML) face disproportionately poor outcomes, driven by a combination of high-risk...
Advancing Bladder Cancer Management: The Role of Neoadjuvant and Adjuvant Therapies and Biomarkers in Muscle Invasive Bladder Cancer
Advancing Bladder Cancer Management: The Role of Neoadjuvant and Adjuvant Therapies and Biomarkers in Muscle Invasive Bladder Cancer
The management of muscle-invasive bladder cancer (MIBC) is evolving rapidly, with the integration of neoadjuvant and adjuv...
Update in the Management of ACTH-Secreting Gastroenteropancreatic and Thoracic Neuroendocrine Neoplasms
Update in the Management of ACTH-Secreting Gastroenteropancreatic and Thoracic Neuroendocrine Neoplasms
The adrenocorticotropic hormone (ACTH)-secreting neuroendocrine neoplasms (NENs) represent a rare but frequently severe di...
Dermatofibrosarcoma Protuberans (DFSP): Current Treatments and Clinical Trials
Dermatofibrosarcoma Protuberans (DFSP): Current Treatments and Clinical Trials
Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue sarcoma with an incidence of 0.008 to 0.045 cases per 100,000...
Social Determinants of Health in Cardio Oncology, from Evidence To Action: Translating Concepts into Clinical Practice Through Implementation Science
Social Determinants of Health in Cardio Oncology, from Evidence To Action: Translating Concepts into Clinical Practice Through Implementation Science
As cardio-oncology matures, its continued inattention to the social determinants of health (SDOH) represents a critical bl...
Second-Line Treatment in cholangiocarcinoma - Current State of the Art and Future Perspectives
Second-Line Treatment in cholangiocarcinoma - Current State of the Art and Future Perspectives
The current landscape of second-line treatment for cholangiocarcinoma (CCA) appears to be evolving, with emerging strategi...
Advances in the Pathogenesis, Diagnosis, Treatment, and Prognosis of Marginal Zone Lymphoma
Advances in the Pathogenesis, Diagnosis, Treatment, and Prognosis of Marginal Zone Lymphoma
The management of marginal zone lymphoma (MZL), an indolent B-cell non-Hodgkin lymphoma, requires a personalized and adapt...
Impact of Genetic Polymorphisms on Treatment Outcomes of Proteasome Inhibitors and Immunomodulatory Drugs in Multiple Myeloma
Impact of Genetic Polymorphisms on Treatment Outcomes of Proteasome Inhibitors and Immunomodulatory Drugs in Multiple Myeloma
Multiple myeloma (MM) is classified as a lymphoproliferative disorder that remains an incurable malignancy despite improve...
Recent Advances in Succinate Dehydrogenase Deficient Gastrointestinal Stromal Tumor Systemic Therapies
Recent Advances in Succinate Dehydrogenase Deficient Gastrointestinal Stromal Tumor Systemic Therapies
Gastrointestinal stromal tumors (GIST) are the most common gastrointestinal soft tissue sarcomas, with an incidence of abo...
Enhancing Colorectal Cancer Treatment Through VEGF/VEGFR Inhibitors and Immunotherapy
Enhancing Colorectal Cancer Treatment Through VEGF/VEGFR Inhibitors and Immunotherapy
Colorectal cancer, ranking as the third most prevalent malignancy globally, substantially benefits from both immunotherapy...
Evolving Landscape of HER2-Targeted Therapies for Gastric Cancer Patients
Evolving Landscape of HER2-Targeted Therapies for Gastric Cancer Patients
Gastric cancer (GC) is a deadly disease worldwide, and trastuzumab in combination with chemotherapy has been the standard ...
Unlocking the Therapeutic Potential of Natural Polyphenols in Esophageal Cancer
Unlocking the Therapeutic Potential of Natural Polyphenols in Esophageal Cancer
Esophageal cancer (EC), one highly malignant upper gastrointestinal cancer, is the eighth most commonly occurring cancer a...
Advances in PSMA-Targeted Radionuclide Therapeutics
Advances in PSMA-Targeted Radionuclide Therapeutics
Prostate-specific membrane antigen targeted radionuclide therapies (PSMA-TRT) such as 177Lu-PSMA-617 hold great promise in...
Review of Bone Metastasis in Gynecologic Malignancies: Evaluation and Treatment
Review of Bone Metastasis in Gynecologic Malignancies: Evaluation and Treatment
Metastatic bone disease (MBD) is a significant source of morbidity and mortality in cancer patients with solid tumors, inc...
Role of Geriatric Assessment in Hematopoietic Stem Cell Transplant and Cellular Therapies
Role of Geriatric Assessment in Hematopoietic Stem Cell Transplant and Cellular Therapies
Hematological malignancies are common among older adults, a group that faces unique challenges in treatment. While hematop...
Current status of Complementary and Alternative Medicine Interventions in the Management of Pancreatic Cancer – An Overview
Current status of Complementary and Alternative Medicine Interventions in the Management of Pancreatic Cancer – An Overview
Pancreatic cancer (PC) remains the deadliest cancer worldwide. Most patients are diagnosed at the advanced or metastatic s...
Cardiovascular Adverse Events of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia: Clinical Relevance, Impact on Outcome, Preventive Measures and Treatment Strategies
Cardiovascular Adverse Events of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia: Clinical Relevance, Impact on Outcome, Preventive Measures and Treatment Strategies
The introduction of TKIs into the therapeutic armamentarium of CML has changed the disease paradigm, increasing long-term ...
The Quest for Circulating Biomarkers in Neuroendocrine Neoplasms: a Clinical Perspective
The Quest for Circulating Biomarkers in Neuroendocrine Neoplasms: a Clinical Perspective
Given the considerable heterogeneity in neuroendocrine neoplasms (NENs), it appears unlikely that a sole biomarker exists ...
Updates in Management of Malignant Pleural Mesothelioma
Updates in Management of Malignant Pleural Mesothelioma
Malignant pleural mesothelioma (MPM) is an aggressive asbestos-associated thoracic malignancy that is usually incurable. A...
The Evolving Treatment Landscape of Medullary Thyroid Cancer
The Evolving Treatment Landscape of Medullary Thyroid Cancer
Genetic assessment is crucial to address the correct treatment for advanced medullary thyroid cancer (MTC). Multi tyrosine...
Application of Engineered Dendritic Cell Vaccines in Cancer Immunotherapy: Challenges and Opportunities
Application of Engineered Dendritic Cell Vaccines in Cancer Immunotherapy: Challenges and Opportunities
The primary objective of this study is to evaluate the effectiveness of cancer vaccines containing genetically modified de...
Selecting Optimal First-Line Treatment for Microsatellite Stable and Non-Mutated RAS/BRAF Metastatic Colorectal Cancer
Selecting Optimal First-Line Treatment for Microsatellite Stable and Non-Mutated RAS/BRAF Metastatic Colorectal Cancer
Standard frontline treatment of metastatic colorectal cancer (CRC) is cytotoxic chemotherapy plus a biologic agent such as...
Anti-HER2 Drugs for the Treatment of Advanced HER2 Positive Breast Cancer
Anti-HER2 Drugs for the Treatment of Advanced HER2 Positive Breast Cancer
Approximately 15–20% of breast cancers (BC) demonstrate HER2 overexpression/gene amplification. Historically, before...
Update of Diagnosis and Targeted Therapy for ALK+ Inflammation Myofibroblastic Tumor
Update of Diagnosis and Targeted Therapy for ALK+ Inflammation Myofibroblastic Tumor
Inflammatory myofibroblastic tumor (IMT), characterized by intermediate malignancy and a propensity for recurrence, has pr...
Frontiers of Ovarian Carcinosarcoma
Frontiers of Ovarian Carcinosarcoma
Ovarian carcinosarcoma (OCS), also known as a malignant mixed Müllerian tumour (MMMT), is a rare and aggressive form ...
The Role of Liver Transplantation in the Treatment of Liver Metastases from Neuroendocrine Tumors
The Role of Liver Transplantation in the Treatment of Liver Metastases from Neuroendocrine Tumors
Transplant oncology is a new field of medicine referred to the use of solid organ transplantation, particularly the liver,...
Developing Strategies to Improve the Efficacy of CAR-T Therapy for Acute Myeloid Leukemia
Developing Strategies to Improve the Efficacy of CAR-T Therapy for Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a fatal blood malignancy. With the development of immunotherapy, particularly chimeric ant...
Systemic Therapy in Advanced Pleomorphic Liposarcoma: a Comprehensive Review
Systemic Therapy in Advanced Pleomorphic Liposarcoma: a Comprehensive Review
The therapeutic approach of pleomorphic liposarcoma (PLPS), a rare high-grade subgroup of soft tissue sarcoma, is commonly...
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