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Brigatinib treatment in a patient with advanced NSCLC with XPO1-ALK fusion: a case report
1 IntroductionNSCLC, which is a malignant tumor of epithelial origin, accounts for 85%-88% of all lung cancer cases; NSCLC...
Targeting the kynurenine pathway: another therapeutic opportunity in the metabolic crosstalk between cancer and immune cells
IntroductionDrug resistance in cancer remains a formidable challenge in modern oncology, severely limiting the efficacy of...
Changes in gut microbiota after gastric cancer surgery: a prospective longitudinal study
1 IntroductionGastric cancer (GC) is a global health issue, being the fifth most prevalent cancer and the third leading ca...
Case report: Gastric langerhans cell histiocytosis with BRAF deletion mutation in a child that was misdiagnosed as lymphoma
1 IntroductionLangerhans cell histiocytosis (LCH) is a myeloid neoplasm of mixed cellularity, which is characterized by ac...
Natural killer cell engagers for cancer immunotherapy
1 IntroductionAntibody-mediated cancer immunotherapy is a type of treatment approach that harnesses the power of antibodie...
HLA-DMB correlates with antitumor immunity and an improved prognosis in endometrial carcinoma tumors
1 IntroductionEndometrial cancer is the sixth most common cancer among women, with an overall incidence that has risen by ...
A comparative analysis and survival analysis of open versus minimally invasive radical antegrade modular pancreatosplenectomy for pancreatic cancer: a systematic review and meta-analysis
1 IntroductionPancreatic ductal adenocarcinoma (PDAC) is a significant threat to human health, ranking as the fourth leadi...
Rare skin adverse reactions induced by osimertinib: a case report and literature review
IntroductionLung cancer is the leading cause of cancer-related deaths worldwide, with approximately 85% of cases attribute...
Prognostic role of prognostic nutritional index in patients with bladder cancer: a systematic review and meta-analysis
IntroductionBladder cancer is one of the most common malignant tumors of the urinary system, originating from the urotheli...
Interactions between key genes and pathways in prostate cancer progression and therapy resistance
1 IntroductionProstate cancer is currently the most common malignancy among men in the United States, with an incidence of...
Ferroptosis in thyroid cancer: mechanisms, current status, and treatment
1 IntroductionThyroid cancer represents the most frequently diagnosed malignancy within the endocrine system and encompass...
A dosimetric comparison of non-coplanar volumetric modulated arc therapy and non-coplanar fixed field intensity modulated radiation therapy in hippocampus-avoidance whole-brain radiation therapy with a simultaneous integrated boost for brain metastases
1 IntroductionOver the past few years, the incidence rate of brain metastases has increased consistently (1). Whole brain ...
Hepatic epithelioid hemangioendothelioma with TFE3 rearrangement: a case report and literature review
1 IntroductionEpithelioid hemangioendothelioma (EHE) is a rare malignant vascular tumor, that often occurs in soft tissues...
Proof of concept of fully automated adaptive workflow for head and neck radiotherapy treatments with a conventional linear accelerator
1 IntroductionHead and neck cancer is a challenging site to treat in terms of contour definition, planning technique and a...
Effectiveness and safety of pembrolizumab, nivolumab, and atezolizumab as adjuvant therapy for high-risk muscle-invasive urothelial carcinoma: an indirect comparison
1 IntroductionDespite advancements in treatment, management of muscle-invasive urothelial carcinoma (MIUC) continues to be...
Impact of social determinants and medical mistrust on parent-child HPV vaccination in economically disadvantaged communities: implications for cancer prevention
IntroductionAround 37,000 new cases of cancer annually in the United States can be linked to human papillomavirus (HPV), p...
Pulmonary enteric adenocarcinoma with progression disease after second - line therapy: a case report
IntroductionLung adenocarcinoma is the most common histological type of non-small cell lung cancer (NSCLC) (1), with a var...
The effect of baseline versus early glucocorticoid use on immune checkpoint inhibitor efficacy in patients with advanced NSCLC
1 IntroductionImmune checkpoint inhibitors (ICIs) have become the standard treatment for non-small cell lung cancer (NSCLC...
Association between dietary antioxidants, serum albumin/globulin ratio and quality of life in esophageal squamous cell carcinoma patients: a 7-year follow-up study
IntroductionEsophageal cancer (EC) is the 11th most common cancer worldwide and the seventh leading cause of cancer-relate...
Development and approval of a Lasso score based on nutritional and inflammatory parameters to predict prognosis in patients with glioma
1 IntroductionGliomas constitute the most prevalent intracranial tumors in the central nervous system. Originating primari...
Case report: 177Lu DOTA-TATE: a new scheme for the treatment of prostate neuroendocrine cancer
Case report: 177Lu DOTA-TATE: a new scheme for the treatment of prostate neuroendocrine cancer
BackgroundMost instances of small cell carcinoma originate from the lungs, while the gastrointestinal tract serves as a se...
The complex nature of lncRNA-mediated chromatin dynamics in multiple myeloma
The complex nature of lncRNA-mediated chromatin dynamics in multiple myeloma
Extensive genome-wide sequencing efforts have unveiled the intricate regulatory potential of long non-protein coding RNAs ...
Vascular co-option in resistance to anti-angiogenic therapy
Vascular co-option in resistance to anti-angiogenic therapy
Three different mechanisms of neovascularization have been described in tumor growth, including sprouting angiogenesis, in...
Case Report: Leiomyosarcoma of the right external iliac artery: a diagnostic-based study on a rare case
Case Report: Leiomyosarcoma of the right external iliac artery: a diagnostic-based study on a rare case
Leiomyosarcoma (LMS) is an uncommon and aggressive form of cancer that originates in the smooth muscles. It possesses the ...
Growth differentiation factor 15 (GDF15) elevation in children with newly diagnosed cancer
Growth differentiation factor 15 (GDF15) elevation in children with newly diagnosed cancer
BackgroundGrowth differentiation factor 15 (GDF15), an inflammatory marker and mediator of adult cancer cachexia, remains ...
AI/ML advances in non-small cell lung cancer biomarker discovery
AI/ML advances in non-small cell lung cancer biomarker discovery
Lung cancer is the leading cause of cancer deaths among both men and women, representing approximately 25% of cancer fatal...
Overview and characterization of penile cancer content across social media platforms
Overview and characterization of penile cancer content across social media platforms
BackgroundSocial media platforms (SMP) are an emerging resource that allows physicians, patients, and families to converse...
The emergence of Fanconi anaemia type S: a phenotypic spectrum of biallelic BRCA1 mutations
The emergence of Fanconi anaemia type S: a phenotypic spectrum of biallelic BRCA1 mutations
BRCA1 is involved in the Fanconi anaemia (FA) pathway, which coordinates repair of DNA interstrand cross-links. FA is a ra...
Anlotinib combined with radiotherapy and chemotherapy for recurrent pelvic osteosarcoma treatment: a case report and literature review
Anlotinib combined with radiotherapy and chemotherapy for recurrent pelvic osteosarcoma treatment: a case report and literature review
At present, the treatment of recurrent pelvic osteosarcoma is too simple, and most of the patients are treated with chemot...
Targeted therapy for pediatric central nervous system tumors harboring mutagenic tropomyosin receptor kinases
Targeted therapy for pediatric central nervous system tumors harboring mutagenic tropomyosin receptor kinases
The family of the neurotrophic tyrosine kinase receptor (NTRK) gene encodes for members of the tropomyosin receptor kinase...
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