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Advances in the Use of Immune Checkpoint Inhibitors for Colorectal Cancer Treatment
Advances in the Use of Immune Checkpoint Inhibitors for Colorectal Cancer Treatment
Providing a comprehensive overview of registered clinical trials on ICIs in Colorectal cancer worldwide. Read more
L-Sarcolysine Reduced the Mobility of Human Glioblastoma Cells, with Potential Involvement of Vimentin
L-Sarcolysine Reduced the Mobility of Human Glioblastoma Cells, with Potential Involvement of Vimentin
These findings underscore the potential of targeting vimentin to curb GBM metastasis, while also emphasizing the need for ...
Evaluating the Prognostic Value of a Pan-Cancer Circulating Tumor DNA Next-Generation Sequencing Panel in Advanced Cancer Patients
Evaluating the Prognostic Value of a Pan-Cancer Circulating Tumor DNA Next-Generation Sequencing Panel in Advanced Cancer Patients
Evaluating the clinical utility of a pan-cancer ctDNA NGS panel for predicting treatment response and PFS in patients with...
Personalized Treatment for Invasive Ductal Breast Carcinoma with Lung and Liver Metastases Based on Patient-Derived Organoids: A Case Report
Personalized Treatment for Invasive Ductal Breast Carcinoma with Lung and Liver Metastases Based on Patient-Derived Organoids: A Case Report
A case of invasive ductal breast carcinoma with lung and liver metastases who obtained efficient response to the sensitive...
Metastatic Laryngeal Minor Salivary Gland Carcinoma to the Liver: Successful Treatment with Anti-EGFR-Based Combination Therapy - A Case Report and Literature Review
Metastatic Laryngeal Minor Salivary Gland Carcinoma to the Liver: Successful Treatment with Anti-EGFR-Based Combination Therapy - A Case Report and Literature Review
A case of a 43-year-old male with a history of surgically resected laryngeal ductal carcinoma who developed liver metastases
Real-World Experience of Niraparib as Maintenance Therapy in Patients with Newly Diagnosed Advanced Ovarian Cancer: A Single-Center Retrospective Study
Real-World Experience of Niraparib as Maintenance Therapy in Patients with Newly Diagnosed Advanced Ovarian Cancer: A Single-Center Retrospective Study
Evaluating the efficacy and safety of niraparib as a maintenance treatment for newly diagnosed advanced ovarian cancer in ...
miR-424-3p Contributes to the Malignant Progression and Chemoresistance of Gastric Cancer [Retraction]
miR-424-3p Contributes to the Malignant Progression and Chemoresistance of Gastric Cancer [Retraction]
Retraction for the article miR-424-3p Contributes to the Malignant Progression and Chemoresistance of Gastric Cancer
Decoding the Prognosis-Related S100A9high Monocyte in Glioblastoma Using Single-Cell and Spatial Transcriptome Sequencing
Decoding the Prognosis-Related S100A9high Monocyte in Glioblastoma Using Single-Cell and Spatial Transcriptome Sequencing
in this study, we identified the novel immunosuppressive monocyte sub-population as well as the potential signaling pathwa...
Patients with Advanced Non-Small Cell Lung Cancer and the EGFR Exon 19 Deletion p.L747 Benefit from Chemotherapy and First-Generation Tyrosine Kinase Inhibitors Compared with Patients with p.E746
Patients with Advanced Non-Small Cell Lung Cancer and the EGFR Exon 19 Deletion p.L747 Benefit from Chemotherapy and First-Generation Tyrosine Kinase Inhibitors Compared with Patients with p.E746
Investigating how chemotherapy and EGFR 19del subtypes affect clinical outcomes of patients with advanced NSCLC treated wi...
Targeting ANXA4 to Overcome Cisplatin Resistance in Ovarian Cancer: A Bioinformatics and in Vitro Study
Targeting ANXA4 to Overcome Cisplatin Resistance in Ovarian Cancer: A Bioinformatics and in Vitro Study
Targeting ANXA4 may offer a novel therapeutic strategy to overcome chemoresistance and improve treatment outcomes in patie...
Forkhead Box S1 Inhibits the Progression of Hepatocellular Carcinoma [Retraction]
Forkhead Box S1 Inhibits the Progression of Hepatocellular Carcinoma [Retraction]
Retraction for the article Forkhead Box S1 Inhibits the Progression of Hepatocellular Carcinoma
Redefining Therapeutic Boundaries: PD-1 Blockade Facilitates Surgical Cure in EGFR-TKI Refractory EGFR-Mutant NSCLC with Pleural Metastases
Redefining Therapeutic Boundaries: PD-1 Blockade Facilitates Surgical Cure in EGFR-TKI Refractory EGFR-Mutant NSCLC with Pleural Metastases
Presenting a case of 57-year-old female initially diagnosed with stage cT3N1M1a (IVA) EGFR L858R-mutant lung adenocarcinom...
Icariin Inhibits Lung Adenocarcinoma Progression Through TP53-Mediated Ferroptosis
Icariin Inhibits Lung Adenocarcinoma Progression Through TP53-Mediated Ferroptosis
ICA exhibits antitumor effects in LUAD by activating TP53-mediated ferroptosis, effectively inhibiting cellular proliferat...
SNRPE is Associated with ERK/mTOR Signaling Activation and Reduced Autophagy to Promote Lung Adenocarcinoma Cell Proliferation
SNRPE is Associated with ERK/mTOR Signaling Activation and Reduced Autophagy to Promote Lung Adenocarcinoma Cell Proliferation
To evaluate SNRPE expression and explore the link in ERK/mTOR signaling, with the aim of identifying a potential therapeut...
Diagnosis and Management of Colorectal Cancer in the Gulf Area: Current Practice and Future Suggestions from Expert Opinions
Diagnosis and Management of Colorectal Cancer in the Gulf Area: Current Practice and Future Suggestions from Expert Opinions
This article aims to summarize these expert opinions, help clinicians make informed decisions, and guide the management of...
Integrative Multi-Omics and Functional Characterization Reveal MCM4 as a Key Oncogenic Regulator in Hepatocellular Carcinoma
Integrative Multi-Omics and Functional Characterization Reveal MCM4 as a Key Oncogenic Regulator in Hepatocellular Carcinoma
Performing integrative bioinformatics analyses on three public HCC datasets (GSE14520, GSE56545, and GSE84402) to identify...
Fatal Steroid-Refractory Autoimmune Encephalitis Following Sequential Immune Checkpoint Inhibitor Therapy in Squamous Non-Small Cell Lung Cancer
Fatal Steroid-Refractory Autoimmune Encephalitis Following Sequential Immune Checkpoint Inhibitor Therapy in Squamous Non-Small Cell Lung Cancer
Suspected steroid-refractory autoimmune encephalitis in a patient with squamous non-small cell lung cancer after sequentia...
Prognostic Impact of Pre-Treatment CRP/Albumin Ratio in Patients with Advanced-Stage Epithelial Ovarian Cancer
Prognostic Impact of Pre-Treatment CRP/Albumin Ratio in Patients with Advanced-Stage Epithelial Ovarian Cancer
Determining whether the pre-treatment CRP/albumin ratio offers independent prognostic value beyond conventional parameters...
Brain Metastatic Tumor Flare After Sunvozertinib Dose Reduction in a Patient with Surgical Resected EGFR ex20ins NSCLC
Brain Metastatic Tumor Flare After Sunvozertinib Dose Reduction in a Patient with Surgical Resected EGFR ex20ins NSCLC
A case of EGFR ex20ins NSCLC, in which targeted therapy with sunvozertinib downstaged metastatic N3 lymph node and primed ...
Clinical Significance of MYBL2 Expression in Hepatocellular Carcinoma: Impact on Overall Survival
Clinical Significance of MYBL2 Expression in Hepatocellular Carcinoma: Impact on Overall Survival
The aim of this study was to evaluate the expression of MYBL2 in tumorous and non-tumorous tissue samples from HCC patient...
Multi-Omics Analysis Revealed That TAOK1 Can Be Used as a Prognostic Marker and Target in a Variety of Tumors, Especially in Cervical Cancer
Multi-Omics Analysis Revealed That TAOK1 Can Be Used as a Prognostic Marker and Target in a Variety of Tumors, Especially in Cervical Cancer
TAOK1 serves as a promising prognostic biomarker and potential therapeutic target, especially for cervical cancer.
Evaluation of Indoleamine 2,3-Dioxygenase (IDO) Expression in Osteosarcoma: Insights From a 10-Year Retrospective Cohort
Evaluation of Indoleamine 2,3-Dioxygenase (IDO) Expression in Osteosarcoma: Insights From a 10-Year Retrospective Cohort
We explore IDO expression in primary tumors and metastatic lesions among osteosarcoma patients, and its association with c...
Clinical Impact of Osimertinib Dose Reduction in the First-Line Setting on EGFR Mutation-Positive Non-Small Cell Lung Cancer: A Retrospective Monocentric Study
Clinical Impact of Osimertinib Dose Reduction in the First-Line Setting on EGFR Mutation-Positive Non-Small Cell Lung Cancer: A Retrospective Monocentric Study
The present, monocentric, retrospective study was conducted to identify the clinical course, efficacy, and safety of osime...
Prognostic and Immunological Significance of NMNAT1 in Colorectal and Pan-Cancer Contexts
Prognostic and Immunological Significance of NMNAT1 in Colorectal and Pan-Cancer Contexts
The aim of this study was to understand the prognostic and immunological significance of nicotinamide metabolism-related g...
PCSK9 Manipulates Lipid Metabolism and the Immune Microenvironment in Cancer
PCSK9 Manipulates Lipid Metabolism and the Immune Microenvironment in Cancer
Current state of knowledge regarding the role and underlying mechanisms of PCSK9 in tumorigenesis, progression, immune esc...
Genomic Insights Into Early Relapsed Breast Cancer: Prognostic Challenges and Mutation Landscape
Genomic Insights Into Early Relapsed Breast Cancer: Prognostic Challenges and Mutation Landscape
The clinicopathological & molecular characteristics of early recurrent metastatic breast cancer, its prognostic factor...
Integrating Bulk and Single-Cell RNA Sequencing Data Reveals the Prognostic Significance of HOXC9-Related Immune Gene Signatures in Hepatocellular Carcinoma
Integrating Bulk and Single-Cell RNA Sequencing Data Reveals the Prognostic Significance of HOXC9-Related Immune Gene Signatures in Hepatocellular Carcinoma
HOXC9 is overexpressed in HCC and correlates with poor prognosis. The HRIG-based risk score model effectively evaluates th...
Coumarins from Citrus aurantiifolia (Christm.) Swingle Peel with Potential Cytotoxic Activity Against MCF-7 Breast Cancer Cell Line: In Vitro and In Silico Studies
Coumarins from Citrus aurantiifolia (Christm.) Swingle Peel with Potential Cytotoxic Activity Against MCF-7 Breast Cancer Cell Line: In Vitro and In Silico Studies
Potency of phenolic compounds from Citrus aurantiifolia (Christm.) Swingle peel as alternative treatment for breast cancer...
Exploring Protein Expression Profiles in Lung Cancer Insufficient Microwave Ablation: Implications for Recurrence
Exploring Protein Expression Profiles in Lung Cancer Insufficient Microwave Ablation: Implications for Recurrence
Insufficient ablation can cause alterations in nucleotide metabolism, potentially leading to recurrence and metastasis.
Waldenström Macroglobulinemia and Chronic Myelomonocytic Leukemia: Case Report and Literature Review
Waldenström Macroglobulinemia and Chronic Myelomonocytic Leukemia: Case Report and Literature Review
Reporting the case of a patient with Waldenström macroglobulinemia and chronic myelomonocytic leukemia who accepted h...
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