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Hereditary Hematopoietic Malignancies: Considerations for Optimizing Diagnosis and Management
Hereditary Hematopoietic Malignancies: Considerations for Optimizing Diagnosis and Management
Hereditary hematopoietic malignancies (HHMs) were once considered extremely rare. As diagnostic testing indications and me...
Brain Tumor Related Epilepsy: Pathophysiology and Multimodal Approach to Management
Brain Tumor Related Epilepsy: Pathophysiology and Multimodal Approach to Management
Patients with brain tumor related epilepsy (BTRE) represent a heterogenous group whose management is complicated by two di...
The Role of Circulating Tumor DNA in Patients Treated with Adjuvant Immune Checkpoint Inhibitors: Clinical Reality or Distant Horizon?
The Role of Circulating Tumor DNA in Patients Treated with Adjuvant Immune Checkpoint Inhibitors: Clinical Reality or Distant Horizon?
Adjuvant immunotherapy has improved outcomes in several cancers, although patient selection and toxicity remain challenges...
Ivermectin in Cancer Treatment: Should Healthcare Providers Caution or Explore Its Therapeutic Potential?
Ivermectin in Cancer Treatment: Should Healthcare Providers Caution or Explore Its Therapeutic Potential?
This review evaluates the scientific evidence for Ivermectin’s potential anticancer properties, an antiparasitic dru...
Indications of Cannabinoids for the Palliation of Cancer-Associated Symptoms: A Systematic Review and Meta-Analysis
Indications of Cannabinoids for the Palliation of Cancer-Associated Symptoms: A Systematic Review and Meta-Analysis
As cancer survival rates are increasing, alternative treatments to improve quality of life, such as cannabinoids, are gain...
Navigating the Colorectal Cancer Maze: Unveiling Pathways To Diagnosis, Management, Pathophysiology and Prevention
Navigating the Colorectal Cancer Maze: Unveiling Pathways To Diagnosis, Management, Pathophysiology and Prevention
Colorectal cancer is the third most prevalent cancer globally and the second leading cause of cancer-related mortality. It...
Cardiotoxic Effects Following CAR-T Cell Therapy: A Literature Review
Cardiotoxic Effects Following CAR-T Cell Therapy: A Literature Review
This paper reviewed the current literature on incidence, clinical manifestations, and risk factors of Chimeric Antigen Rec...
Advances in Radiation Oncology in Soft Tissue Sarcoma
Advances in Radiation Oncology in Soft Tissue Sarcoma
To review recent advances with radiation therapy (RT) for soft tissue sarcomas (STS). Newer data showcases hypofractionate...
Quality End-of-Life Cancer Care: An Unfulfilled but Achievable Imperative
Quality End-of-Life Cancer Care: An Unfulfilled but Achievable Imperative
Disease-focus management of late-stage cancer without addressing patients’ preferences or quality of life (QoL) can ...
Novel Surgical Initiatives in Gastroenteropancreatic Neuroendocrine Tumours
Novel Surgical Initiatives in Gastroenteropancreatic Neuroendocrine Tumours
Neuroendocrine tumours (NET) are rare entities arising from hormone producing cells in the gastroentero-pancreatic (GEP) t...
Weight Management for Fertility-Preservation Therapy in Endometrial Cancer: Opportunities and Challenges
Weight Management for Fertility-Preservation Therapy in Endometrial Cancer: Opportunities and Challenges
Obesity is increasingly recognized as a significant factor impacting the outcomes of fertility-preserving therapies for en...
Paediatric Renal Tumors: A State-of-the-Art Review
Paediatric Renal Tumors: A State-of-the-Art Review
Pediatric renal tumors comprise a wide range of conditions, both malignant and benign, that affect children and require a ...
Cell-free Tumor DNA: a Promising Technology for Diagnosis, Surveillance and Therapeutic Decision in Urothelial Carcinoma of the Bladder
Cell-free Tumor DNA: a Promising Technology for Diagnosis, Surveillance and Therapeutic Decision in Urothelial Carcinoma of the Bladder
This narrative review aims to discuss the latest evidence for cell-free tumor DNA (ctDNA) use in bladder cancer, future pe...
Current State of Evidence on Definitions and Management of High-Risk Multiple Myeloma
Current State of Evidence on Definitions and Management of High-Risk Multiple Myeloma
This review aims to address the subgroup of patients with newly diagnosed multiple myeloma (NDMM) who have high-risk multi...
Defining The Role for Hormone Therapy in Biochemically Recurrent Prostate Cancer: What Counts as a Win for Patients?
Defining The Role for Hormone Therapy in Biochemically Recurrent Prostate Cancer: What Counts as a Win for Patients?
We evaluate unique clinical and drug development challenges in biochemically recurrent (BCR) prostate cancer. We examine r...
Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors
This review aims to outline the current understanding of the molecular drivers and treatment paradigms of gastrointestinal...
ChatGPT in Oncology Diagnosis and Treatment: Applications, Legal and Ethical Challenges
ChatGPT in Oncology Diagnosis and Treatment: Applications, Legal and Ethical Challenges
This study aims to systematically review the trajectory of artificial intelligence (AI) development in the medical field, ...
Beneath the Surface: The Emerging Role of Ultra-Processed Foods in Obesity-Related Cancer
Beneath the Surface: The Emerging Role of Ultra-Processed Foods in Obesity-Related Cancer
Ultra-processed foods (UPFs) are becoming more and more important in daily diets around the world; in some cases, they can...
Emerging Therapeutic Targets of Neuroendocrine Prostate Cancer
Emerging Therapeutic Targets of Neuroendocrine Prostate Cancer
Treatment-emergent neuroendocrine prostate cancer (NEPC) is aggressive and lethal. As androgen receptor signaling inhibito...
Correction to: Postmastectomy Functional Impairments
Correction to: Postmastectomy Functional Impairments
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Integrative Approaches in the Treatment of Patients Affected by Lymphoma
Integrative Approaches in the Treatment of Patients Affected by Lymphoma
Lymphoma is the most frequent hematological malignancy with wide disease spectrum of watchful waiting period, active treat...
Shifting Strategies in the Treatment of Pediatric Craniopharyngioma
Shifting Strategies in the Treatment of Pediatric Craniopharyngioma
Craniopharyngiomas represent one of the most challenging diseases to treat. Despite their benign histology, and after many...
Genomic Landscape of Pleural Mesothelioma and Therapeutic Aftermaths
Genomic Landscape of Pleural Mesothelioma and Therapeutic Aftermaths
In this article, we provide a comprehensive analysis of recent progress in the genetic characterisation of pleural mesothe...
Limb Amputations in Cancer: Modern Perspectives, Outcomes, and Alternatives
Limb Amputations in Cancer: Modern Perspectives, Outcomes, and Alternatives
This review summarizes current findings regarding limb amputation within the context of cancer, especially in osteosarcoma...
Postmastectomy Functional Impairments
Postmastectomy Functional Impairments
This narrative review aims to offer a thorough summary of functional impairments commonly encountered by breast cancer sur...
Immune Priming with Spatially Fractionated Radiation Therapy
Immune Priming with Spatially Fractionated Radiation Therapy
This review aims to summarize the current preclinical and clinical evidence of nontargeted immune effects of spatially fra...
Advances in Treatment of Waldenström Macroglobulinemia
Advances in Treatment of Waldenström Macroglobulinemia
The discovery of recurring somatic mutations, in particular MYD88 and CXCR4 mutations, in Waldenström macroglobulinem...
What Is New in Cutaneous T Cell Lymphoma?
What Is New in Cutaneous T Cell Lymphoma?
This review focuses on updates in prognosis, pathogenesis, and treatment of cutaneous T cell lymphoma (CTCL). Cohort studi...
Prostate Cancer in Transgender Women: Epidemiology, Clinical Characteristics, and Management Challenges
Prostate Cancer in Transgender Women: Epidemiology, Clinical Characteristics, and Management Challenges
To systematically review the evidence on prostate cancer (PCa) in transgender women (TGW). A total of 25 studies were incl...
Navigating the Rapidly Evolving Advanced Urothelial Carcinoma Treatment Landscape: Insights from Italian Experts
Navigating the Rapidly Evolving Advanced Urothelial Carcinoma Treatment Landscape: Insights from Italian Experts
To discuss recent advances in the treatment of advanced urothelial carcinoma (UC) and how best to incorporate new therapie...