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Improving the Functional and Antibacterial Properties of an Endoprosthetic Mesh Using Atomic Layer Deposition Technology
Improving the Functional and Antibacterial Properties of an Endoprosthetic Mesh Using Atomic Layer Deposition Technology
Over the past few decades, abdominal wall hernias of various locations have attracted close attention from surgeons in var...
Novel Organotin Complexes with Losartan: Synthesis and Biological Activity
Novel Organotin Complexes with Losartan: Synthesis and Biological Activity
Novel organotin(IV) complexes based on losartan have been synthesized and characterized by 1H, 13C, 119Sn NMR, IR, ESI-MS ...
Development of Technology for Applying Nanocoatings to Surgical Meshes and Study of the Functional Properties of the Resulting Nanofilms
Development of Technology for Applying Nanocoatings to Surgical Meshes and Study of the Functional Properties of the Resulting Nanofilms
—Today, abdominal hernias of various localizations are diagnosed in approximately 7% of the world’s population...
Conference “Human Biochemistry” Dedicated to the 100th Birth Anniversary of Temirbolat Berezov
Conference “Human Biochemistry” Dedicated to the 100th Birth Anniversary of Temirbolat Berezov
Berezov T.T. Role of vitamin B6 in the metabolism of L- and D-amino acids in animals; effect of vitamin B6 deficiency on t...
The Features of the Genetically-Encoded Biosensor to PIP3 Influence on Insulin Signaling in MSCs
The Features of the Genetically-Encoded Biosensor to PIP3 Influence on Insulin Signaling in MSCs
Genetically encoded fluorescent biosensors (GEBs) are extensively utilized for investigating intracellular signaling proce...
Sea Anemone Toxin Hct-S3 Suppresses the Migration of Solid Ehrlich Adenocarcinoma Cells Inoculated into BALB/C Mice
Sea Anemone Toxin Hct-S3 Suppresses the Migration of Solid Ehrlich Adenocarcinoma Cells Inoculated into BALB/C Mice
Malignant tumors represent a serious problem for humanity due to their widespread distribution and severe posttherapeutic ...
The Influence of Elevated Concentrations of Secretory IgA on the Level of Immunocompetent Cells, Cytokines, Reagins, Circulating Immune Complexes, and C-Reactive Protein in the Blood of Practically Healthy Residents of Murmansk Oblast
The Influence of Elevated Concentrations of Secretory IgA on the Level of Immunocompetent Cells, Cytokines, Reagins, Circulating Immune Complexes, and C-Reactive Protein in the Blood of Practically Healthy Residents of Murmansk Oblast
A total of 104 (77 women and 27 men) practically healthy residents of the city of Apatity, Murmansk oblast, aged 21–...
The Role of MicroRNA in the Development of Type 2 Diabetes Mellitus
The Role of MicroRNA in the Development of Type 2 Diabetes Mellitus
The review presents an analysis of literary data on the role of microRNAs in the pathogenesis of type 2 diabetes mellitus ...
Evaluation of Phenylalanine Substitution on the Antimicrobial Properties of Histatin 8 against Wild-Type and Antibiotic-Resistant
Evaluation of Phenylalanine Substitution on the Antimicrobial Properties of Histatin 8 against Wild-Type and Antibiotic-Resistant
The unregulated and inappropriate use of antibiotics triggered the rapid spread of antimicrobial resistance in pathogenic ...
Molecular Genetic Determinants of Pregnancy Pathology
Molecular Genetic Determinants of Pregnancy Pathology
In the modern world, scientists often discuss problems associated with complications of pregnancy and childbirth in women....
Peptide TRPV1 Channel Blocker, HCRG21, Effectively Suppresses Inflammation in a Calcipotriol-Induced Allergic Dermatitis Model
Peptide TRPV1 Channel Blocker, HCRG21, Effectively Suppresses Inflammation in a Calcipotriol-Induced Allergic Dermatitis Model
As a result of application of hydrogels with 0.05 and 0.005% HCRG21 calcipotriol-induced inflammatory swelling and flaking...
Peculiarities of General and Mucosal Immunity in Urban Residents of Murmansk Oblast
Peculiarities of General and Mucosal Immunity in Urban Residents of Murmansk Oblast
The state of general and mucosal immunity was studied in 103 permanently living and working residents of Apatity town, Mur...
Antiglycating and Antioxidant Properties of Atranorin Isolated from Lichen 
Antiglycating and Antioxidant Properties of Atranorin Isolated from Lichen 
Atranorin is one of the main secondary metabolites of lichens of the group of depsides, which are of considerable interest...
Search for New Active Substances for the Development of Pharmaceuticals Using Supercritical Fluid Extraction
Search for New Active Substances for the Development of Pharmaceuticals Using Supercritical Fluid Extraction
The use of supercritical fluids for the extraction of biologically active substances is an extremely urgent task. Extracti...
Pathogenetic Potential of the Epigenetic Status of Genes of Mendelian Forms of Thoracic Aortic Aneurysms
Pathogenetic Potential of the Epigenetic Status of Genes of Mendelian Forms of Thoracic Aortic Aneurysms
Rare pathogenic variants in genes whose protein products form the structure of the extracellular matrix, regulate smooth m...
Procarcinogenic Characteristics of Tryptophan Metabolism in Obese Patients
Procarcinogenic Characteristics of Tryptophan Metabolism in Obese Patients
Tryptophan is an essential amino acid, the catabolism of which occurs in the human body along three main pathways: kynuren...
Saliva Glucose Determination by Biosensor: Method Comparison to Chemiluminescence Immunoassay
Saliva Glucose Determination by Biosensor: Method Comparison to Chemiluminescence Immunoassay
The noninvasive sampling materials and methods have garnered great interest among researchers. Saliva is considered the mo...
The Quantitative Determination of the Total Antioxidant Activity of Tears
The Quantitative Determination of the Total Antioxidant Activity of Tears
In the present study, the authors developed a protocol for determining the total antioxidant activity of tears. For this p...
Proteolysis and Deficiency of α1-Proteinase Inhibitor in SARS-CoV-2 Infection
Proteolysis and Deficiency of α1-Proteinase Inhibitor in SARS-CoV-2 Infection
The SARS-CoV-2 pandemic had stimulated the emergence of numerous publications on the α1-proteinase inhibitor (α1...
G-Quadruplex Structures in Bacteria: Functional Properties and Prospects for Use as Biotargets
G-Quadruplex Structures in Bacteria: Functional Properties and Prospects for Use as Biotargets
G-quadruplexes (G4), non-canonical secondary DNA structures, have been intensively investigated for a long time. In eukary...
Effect of Ethanol on Platelet Biology
Effect of Ethanol on Platelet Biology
In recent years, there has been interest in the study of platelets, the functions of which, as it turned out, are not limi...
Anti-Ischemic and Antioxidant Activity of the Pharmacological Agonist of Galanin Receptor GalR2 and Carnosine in In Vitro and In Vivo Model Systems
Anti-Ischemic and Antioxidant Activity of the Pharmacological Agonist of Galanin Receptor GalR2 and Carnosine in In Vitro and In Vivo Model Systems
Antioxidant and anti-ischemic properties of the pharmacological agonist of galanin receptor GalR2 WTLNSAGYLLGPβAH (Ga...
Splice Variants of mRNA of Cytochrome P450 Genes: Analysis by the Nanopore Sequencing Method in Human Liver Tissue and HepG2 Cell Line
Splice Variants of mRNA of Cytochrome P450 Genes: Analysis by the Nanopore Sequencing Method in Human Liver Tissue and HepG2 Cell Line
The analysis of cytochrome P450 transcripts was carried out by the nanopore sequencing in liver tissue samples of three do...
Contents of BDNF, miR-30a-5p AND miR-122 during Alcohol Withdrawal Syndrome
Contents of BDNF, miR-30a-5p AND miR-122 during Alcohol Withdrawal Syndrome
Some brain-derived neurotrophic factor (BDNF)-targeted miRNAs such as miR-30a-5p may be associated with alcohol addiction;...
Interaction of Abiraterone and Its Pharmacologically Active Metabolite D4A with Cytochrome P450 2C9 (CYP2C9)
Interaction of Abiraterone and Its Pharmacologically Active Metabolite D4A with Cytochrome P450 2C9 (CYP2C9)
We studied the interaction of the antitumor agent abiraterone and its pharmacologically active metabolite D4A, which is pr...
The Integrin α3β1 Signaling in the Regulation of the SK-Mel-147 Melanoma Cell Senescence
The Integrin α3β1 Signaling in the Regulation of the SK-Mel-147 Melanoma Cell Senescence
Using a model of the human SK-Mel-147 melanoma cell line, it was shown that blocking the expression of integrin α3 ...
Comparative Analysis of Proteins Associated with 26S and 20S Proteasomes Isolated from Rabbit Brain and Liver
Comparative Analysis of Proteins Associated with 26S and 20S Proteasomes Isolated from Rabbit Brain and Liver
The fractions of 26S and 20S proteasomes have been isolated from the rabbit liver and the brain. According to mass spectro...
Population Rearrangement of B Lymphocytes Expressing Chemokine Receptors in Patients with Chronic Obstructive Pulmonary Disease
Population Rearrangement of B Lymphocytes Expressing Chemokine Receptors in Patients with Chronic Obstructive Pulmonary Disease
To date, there are no drugs that can prevent progressive destruction of lung tissue and small airway fibrosis in patients ...
Mechanisms of Development of Side Effects and Drug Resistance to Asparaginase and Ways to Overcome Them
Mechanisms of Development of Side Effects and Drug Resistance to Asparaginase and Ways to Overcome Them
Asparaginase is one of the most important chemotherapeutic agents against acute lymphoblastic leukemia, the most common fo...
Adrenodoxins and Their Role in the Cytochrome P450 Systems
Adrenodoxins and Their Role in the Cytochrome P450 Systems
The role of partner proteins in the formation of functional complexes in cytochrome P450 systems was investigated by means...
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