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LC-QTOF Analysis for Characterization of Degradation Products of Ganirelix Acetate: Exploration of Degradation Pathways and In Silico Toxicity Predictions
LC-QTOF Analysis for Characterization of Degradation Products of Ganirelix Acetate: Exploration of Degradation Pathways and In Silico Toxicity Predictions
Ganirelix acetate (GAN) is a third-generation gonadotropin-releasing hormone (GnRH) antagonist with high antagonistic acti...
Rational Design of Novel Anti-Staphylococcal Peptides Using Machine Learning-Guided QSAR Modeling and Experimental Validation
Rational Design of Novel Anti-Staphylococcal Peptides Using Machine Learning-Guided QSAR Modeling and Experimental Validation
The global health crisis of antibiotic-resistant infections, particularly in chronic wounds, demands innovative therapeuti...
Research Advancements in Peptides for Promoting Reparative Dentin Regeneration in Direct Pulp Capping: A Narrative Review
Research Advancements in Peptides for Promoting Reparative Dentin Regeneration in Direct Pulp Capping: A Narrative Review
Direct pulp capping is an extensively used procedure in clinical practice for preserving pulp vitality and promoting denti...
Bioactive Peptides from Microalgae and Cyanobacteria and Their Possible Mechanisms of Action
Bioactive Peptides from Microalgae and Cyanobacteria and Their Possible Mechanisms of Action
Currently, microalgae and cyanobacteria thrill the researchers with their wide range of applications and diverse health be...
Assessment of the Antimicrobial Efficacy of a Novel Peptide Against : An in Silico and in Vitro Investigation
Assessment of the Antimicrobial Efficacy of a Novel Peptide Against : An in Silico and in Vitro Investigation
P. gingivalis is a significant pathogen in periodontal disease, a chronic inflammatory condition disturbing tooth-supporti...
Functional Peptides in Targeted Cancer Therapy: Mechanisms, Delivery Strategies, and Clinical Perspectives
Functional Peptides in Targeted Cancer Therapy: Mechanisms, Delivery Strategies, and Clinical Perspectives
This review aims to provide a comprehensive analysis of the role of functional peptides in targeted cancer therapy, with a...
Antimicrobial Peptides (AMPs): A Breakthrough Approach for Wound Healing and Infection Control
Antimicrobial Peptides (AMPs): A Breakthrough Approach for Wound Healing and Infection Control
Chronic wounds, such as diabetic ulcers, pressure sores, and burns, remain a global healthcare burden due to the rising th...
Antimicrobial Peptide -Crustin as a Therapeutic Agent against WSSV Infection in Culture System, Conferring Better Protection and Survival
Antimicrobial Peptide -Crustin as a Therapeutic Agent against WSSV Infection in Culture System, Conferring Better Protection and Survival
White Spot Syndrome Virus (WSSV) is a major viral pathogen in shrimp aquaculture, causing high mortality and economic loss...
Enteral Lactoferrin Mitigates Myocardial ischemia-reperfusion Injury Via Enteral Lactoferrin-induced glucagon-like peptide-1 in Isolated Rat Heart Model
Enteral Lactoferrin Mitigates Myocardial ischemia-reperfusion Injury Via Enteral Lactoferrin-induced glucagon-like peptide-1 in Isolated Rat Heart Model
Lactoferrin (LF) administered enterally increases serum glucagon-like peptide-1 (GLP-1) levels, showing cardioprotective e...
A Photolabile Backbone Amide Linker for the Solid-Phase Synthesis of Cyclic Peptides and C-terminal Thioesters
A Photolabile Backbone Amide Linker for the Solid-Phase Synthesis of Cyclic Peptides and C-terminal Thioesters
A new backbone amide linker has been developed for the synthesis of cyclic and C-terminally modified peptides that permits...
Designing and Production of Novel rMEVlhA-MS2/28 Multiepitopes Protein Applicable in Indirect ELISA
Designing and Production of Novel rMEVlhA-MS2/28 Multiepitopes Protein Applicable in Indirect ELISA
Mycoplasma synoviae is a serious pathogen of poultry in worldwide causing severe economic losses. Phase-variable haemagglu...
ML-AMP1 as a Potential Antifungal Agent: Activity and Therapeutic Evaluation in a Guinea Pig Model of Dermatophytosis
ML-AMP1 as a Potential Antifungal Agent: Activity and Therapeutic Evaluation in a Guinea Pig Model of Dermatophytosis
Trichophyton mentagrophytes is a common causative factor of dermatophytosis in humans and animals, and its increasing drug...
Camel Milk Byproduct Peptides as Green Antimicrobial Agents in Biodegradable Packaging Materials: A Comprehensive Review
Camel Milk Byproduct Peptides as Green Antimicrobial Agents in Biodegradable Packaging Materials: A Comprehensive Review
The escalating environmental concerns associated with petroleum-based plastics necessitate the exploration of sustainable ...
Anticancer Therapy Against Glioma by Peptide-Based Therapeutics
Anticancer Therapy Against Glioma by Peptide-Based Therapeutics
Glioma is a form of brain cancer which is not easily dealt with since it grows fast and can spread deep into the brain. Su...
Amelioration of Ethanol-Induced Gastric Ulcer in Rats by Tilapia Skin Derived Collagen And/or Vitamin C: Implication of NFκB/TNFα and BAX/Bcl-2 Pathways
Amelioration of Ethanol-Induced Gastric Ulcer in Rats by Tilapia Skin Derived Collagen And/or Vitamin C: Implication of NFκB/TNFα and BAX/Bcl-2 Pathways
Proton pump inhibitors are the standard treatment for peptic ulcers, but their incomplete curative effect, potential long-...
Oral Peptide Delivery Reimagined: Molecular Barriers, Formulation Strategies, and the Rise of Computational Design
Oral Peptide Delivery Reimagined: Molecular Barriers, Formulation Strategies, and the Rise of Computational Design
The oral delivery of peptide and protein therapeutics remains a significant challenge due to inherent physicochemical limi...
Exploring Therapeutic Potential: An Insight into Neurotensin Modulation of Endotoxemia Driven Hypothalamic Pituitary Adrenal Axis Dysfunction
Exploring Therapeutic Potential: An Insight into Neurotensin Modulation of Endotoxemia Driven Hypothalamic Pituitary Adrenal Axis Dysfunction
Endotoxemia, a life-threatening syndrome, is a major cause of mortality worldwide and disrupts the internal environment of...
A Review of the in Silico Design and Development Approaches of Ras-Specific Anticancer Therapeutics
A Review of the in Silico Design and Development Approaches of Ras-Specific Anticancer Therapeutics
Ras Proteins, play a pivotal role in the proliferation pathways, and Ras mutant forms are well-established cancer drivers....
Cytotoxic Activity of A New Isoform l-Amino Acid Oxidase (Balt-LAAO-II) From Bothrops alternatus (Urutu) Snake Venom in Human Leukemic HL60 Cells
Cytotoxic Activity of A New Isoform l-Amino Acid Oxidase (Balt-LAAO-II) From Bothrops alternatus (Urutu) Snake Venom in Human Leukemic HL60 Cells
In this study, we describe the isolation of a new isoform, l-Amino acid oxidase (LAAO), referred to as Balt-LAAO-II, from ...
Antibacterial Mechanism of a Novel Peptide Dendrocin‑ZM1 Against Staphylococcus aureus by Increasing Membrane Permeability
Antibacterial Mechanism of a Novel Peptide Dendrocin‑ZM1 Against Staphylococcus aureus by Increasing Membrane Permeability
Staphylococcus aureus is a prevalent pathogen responsible for healthcare and community-acquired infections, which lead to ...
Investigating the Effects of Temporin-Rb, an Antimicrobial Peptide, on Cell Viability and Pro-inflammatory Gene Expression in A549 Cells
Investigating the Effects of Temporin-Rb, an Antimicrobial Peptide, on Cell Viability and Pro-inflammatory Gene Expression in A549 Cells
This study investigates the effects of Temporin-Rb, an antimicrobial peptide, on A549 cells’ viability and pro-infla...
Improving the Antibacterial Activity of Tryptophan-Containing Peptide Nanostructures Through Self-Assembly
Improving the Antibacterial Activity of Tryptophan-Containing Peptide Nanostructures Through Self-Assembly
Antimicrobial peptides (AMPs) are frequently distributed in the tissues and organs of animals to exhibit broad-spectrum ac...
Correction: Anti-Inflammatory Mechanism of Walnut Meal Peptide/ Ellagic Acid Nanoparticles on LPS-Stimulated RAW264.7 Cells by Inhibition of NFκB and MAPK Activation
Correction: Anti-Inflammatory Mechanism of Walnut Meal Peptide/ Ellagic Acid Nanoparticles on LPS-Stimulated RAW264.7 Cells by Inhibition of NFκB and MAPK Activation
Correction to: International Journal of Peptide Research and Therapeutics (2023) The original v...
Peptidomic Analysis and Potential Bioactive Peptides Identification Targeting Endometrial Cancer
Peptidomic Analysis and Potential Bioactive Peptides Identification Targeting Endometrial Cancer
Existing evidence has explained the critical role of endogenous peptides in cancers, however, the peptidomic profile and f...
BMAP-27 Peptide Reduces Proliferation and Increases Apoptosis in Primary and Metastatic Colon Cancer Cell Lines
BMAP-27 Peptide Reduces Proliferation and Increases Apoptosis in Primary and Metastatic Colon Cancer Cell Lines
BMAP-27 peptide is reported to possess apoptotic and anti-proliferative effects against cancer cells but the actual mechan...
Anti-Inflammatory Mechanism of Walnut Meal Peptide/ Ellagic Acid Nanoparticles on LPS-Stimulated RAW264.7 Cells by Inhibition of NF-κB and MAPK Activation
Anti-Inflammatory Mechanism of Walnut Meal Peptide/ Ellagic Acid Nanoparticles on LPS-Stimulated RAW264.7 Cells by Inhibition of NF-κB and MAPK Activation
The combined use of walnut meal peptides and ellagic acid demonstrated synergistic anti-inflammatory properties, which cou...
In Vitro Biological Evaluation and Mechanism of Action of Peptoid Analogue Based on Cationic, Amphipathic Peptide A-12
In Vitro Biological Evaluation and Mechanism of Action of Peptoid Analogue Based on Cationic, Amphipathic Peptide A-12
Antimicrobial peptides are thought to be promising antibiotic substitutes for a variety of multidrug-resistant bacteria. N...
Aspartame, a Synthetic Dipeptide Mediated Biochemical and Histopathological Alterations in Hepato-nephric Tissues of Mice and Pharmaceutical Intervention by Sesame Oil
Aspartame, a Synthetic Dipeptide Mediated Biochemical and Histopathological Alterations in Hepato-nephric Tissues of Mice and Pharmaceutical Intervention by Sesame Oil
Aspartame is an artificial sweetener, used worldwide and is one of the most controversial food additives, regarding its sa...
Dried Blood Spot Sampling in Protein and Peptide Bioanalysis: Optimism, Experience, and the Path Forward
Dried Blood Spot Sampling in Protein and Peptide Bioanalysis: Optimism, Experience, and the Path Forward
Dried blood spot (DBS) based microsampling is an emerging approach that requires a minimally invasive procedure. It is bei...
Evaluation of Antimicrobial Property of Bacteriocin Capped Silver Nanoparticles Prepared from Cell Free Supernatant of Lactobacillus brevis Isolated from Marine Fishes
Evaluation of Antimicrobial Property of Bacteriocin Capped Silver Nanoparticles Prepared from Cell Free Supernatant of Lactobacillus brevis Isolated from Marine Fishes
Drug resistance by microbes is becoming a major concern in the field of medicine. The oligo-dynamic nature of silver nanop...
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