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Formulation of naphthol-derived 1,2,3-triazole: A ‘turn-on’ chemosensor for Zr(IV) with anti-cancer and anti-bacterial activities
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Potential zinc phthalocyanine-based photosensitizer for photodynamic therapy: Photophysical, theoretical and in vitro studies
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Decoding the prospective of metal complexes in anti-cancer therapeutics by targeting of G-quadruplex DNA
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Synthesis, characterization and glucose-lowering studies of air-stable, mixed-ligand vanadium(III) acetylacetonates and oxidovanadium(IV) complexes containing pyridine-based ligands.
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NRVS of Fe<img class="glyph" src="https://sdfestaticassets-us-east-1.sciencedirectassets.com/shared-assets/16/entities/sbnd" />S cluster proteins & models – A bestiary of nifty normal modes
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Exploring the chemistry of H2DEDPA derivatives for [nat/68Ga]Ga3+ complexation
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Gold(I) complexes with NHC ligands functionalized with sulfoxide groups: Design, synthesis, in vitro studies and insights into the mechanism of action as anticancer drugs
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Synthesis and anticancer studies of Ru/Ir arene complexes bearing oleanolic acid in acute promyelocytic leukemia cells
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Potent mitochondria-targeting rutheniumII and iridiumIII anticancer complexes containing hybrid N^NH-chelated ligands
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Structure-function relationship within helical peptoids for Cu2+ chelation in the context of Alzheimer's disease
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A molecular basis of Ferredoxin Reductase (FdxR) mutations that result in mitochondriopathies
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Structural studies and biological activity of the new Ni(II), Cu(II), Zn(II), Pd(II), and Ag(I) thiosemicarbazone-based complexes
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Mutation of an active site-adjacent residue in VIM indirectly dictates interactions with and blunts inhibition by D-captopril
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DNA cleavage and antitumoral activity of zinc(II) and iron(III) complexes with a new phenol-based ligand containing uncoordinated thioether moieties
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NMR insights into the behavior of bis-His motifs toward copper ions: A study using mono-N-methylated histidines
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Cobalt complexes as modulators against amyloid-β aggregation
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Multiple catalytic functions of an engineered double mutant of myoglobin with a potential metal-binding site
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The structure of the diheme cytochrome c4 from Neisseria gonorrhoeae reveals multiple contributors to tuning reduction potentials
The structure of the diheme cytochrome c4 from Neisseria gonorrhoeae reveals multiple contributors to tuning reduction potentials
Neisseria gonorrhoeae (Ng) is a human pathogen of growing concern owing to the impact of Ng infections on human health [1,...
A Pt(II) complex bearing N-heterocycle ring induced ferroptotic cell death in ovarian cancer
A Pt(II) complex bearing N-heterocycle ring induced ferroptotic cell death in ovarian cancer
The mortality rate of ovarian cancer is the highest among all gynecological malignancies [1]. Therapeutic strategies consi...
Cytotoxic auranofin analogues bearing phosphine, arsine and stibine ligands: A study on the possible role of the ligand on the biological activity
Cytotoxic auranofin analogues bearing phosphine, arsine and stibine ligands: A study on the possible role of the ligand on the biological activity
In the context of chemotherapeutic drugs, platinum-based complexes have dominated the scene for decades, remaining among t...
Phenanthroline and Schiff Base associated Cu(II)-coordinated compounds containing N, O as donor atoms for potent anticancer activity
Phenanthroline and Schiff Base associated Cu(II)-coordinated compounds containing N, O as donor atoms for potent anticancer activity
Regarding inorganic chemistry, coordination chemistry is at the forefront of innovation and exploration. Since this subfie...
Altering relative metal-binding affinities in multifunctional Metallochaperones for mutant p53 reactivation
Altering relative metal-binding affinities in multifunctional Metallochaperones for mutant p53 reactivation
Recognized as the ‘guardian of the genome’, the p53 protein has been an important drug target since its discovery in 1979 ...
Gold(III) complexes with thiosemicarbazone ligands: insights into their cytotoxic effects on lung cancer cells
Gold(III) complexes with thiosemicarbazone ligands: insights into their cytotoxic effects on lung cancer cells
Cancer continues to pose a global threat, underscoring the urgent need for more effective and safer treatment options. Gol...
A novel benzothiazole-based mononuclear platinum(II) complex displaying potent antiproliferative activity in HepG-2 cells via mitochondrial-mediated apoptosis
A novel benzothiazole-based mononuclear platinum(II) complex displaying potent antiproliferative activity in HepG-2 cells via mitochondrial-mediated apoptosis
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths in the world [1]. The HCC incidence is ...
Synthesis and photothermal conversion properties of sandwich N-fused porphyrin rhodium-μ-dichloride dimer complexes: π-extended analog of pentamethylcyclopentadienyl dirhodium(III)-μ-dichloride dimer
Synthesis and photothermal conversion properties of sandwich N-fused porphyrin rhodium-μ-dichloride dimer complexes: π-extended analog of pentamethylcyclopentadienyl dirhodium(III)-μ-dichloride dimer
In the context of their close resemblance to natural enzymatic systems, tetrapyrrole metal complexes, such as heme, chloro...
Lead to hit ruthenium-cyclopentadienyl anticancer compounds: Cytotoxicity against breast cancer cells, metabolic stability and metabolite profiling
Lead to hit ruthenium-cyclopentadienyl anticancer compounds: Cytotoxicity against breast cancer cells, metabolic stability and metabolite profiling
Over the last decades, many efforts have been devoted towards the development of novel therapeutic approaches to treat can...
Synthesis, characterization and discovery of multiple anticancer mechanisms of dibutyltin complexes based on salen-like ligands
Synthesis, characterization and discovery of multiple anticancer mechanisms of dibutyltin complexes based on salen-like ligands
Oral cancer is a particularly serious oral disease. It occurs in the tongue, lips, cheeks, and floor of the mouth. Oral sq...
Forming a chromium-based interstrand DNA crosslink: Implications for carcinogenicity
Forming a chromium-based interstrand DNA crosslink: Implications for carcinogenicity
When inhaled, chromate is a well-known mutagen and human carcinogen [1]. Unlike cationic Cr(III) complexes, anionic chroma...
Copper(II) complexes with plumbagin and bipyridines target mitochondria for enhanced chemodynamic cancer therapy
Copper(II) complexes with plumbagin and bipyridines target mitochondria for enhanced chemodynamic cancer therapy
Traditional anti-cancer chemotherapy often has toxic and side effects [[1], [2], [3]]. Therefore, the development of novel...
Structure prediction of physiological bis(amino acidato)copper(II) species in aqueous solution: The copper(II) compounds with l-glutamine and l-histidine
Structure prediction of physiological bis(amino acidato)copper(II) species in aqueous solution: The copper(II) compounds with l-glutamine and l-histidine
Copper is both essential and toxic metal for living systems. As an essential trace element, copper participates in physiol...
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