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SCI Abstract
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Comprehensive assessment of the significance of cellular senescence-associated genes in neuroblastoma
The clinical course of high-risk neuroblastoma patients remains suboptimal, and the dynamic and reversible nature of cellu...
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Genome-wide analysis of TCP family genes and their constitutive expression pattern analysis in the melon (Cucumis melo)
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Integrative bioinformatics approaches reveal key hub genes in cyanobacteria: insights from Synechocystis sp. PCC 6803 and Geminocystis sp. NIES-3708 under abiotic stress conditions
Cyanobacteria, particularly Synechocystis sp. PCC 6803, serve as model organisms for studying acclimation strategies that ...
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Transcriptome analysis of wild soybean (Glycine soja) under salt stress and identification of salt-responsive genes
Soil salinity has been a serious threat to agricultural production worldwide, including soybeans. Glycine soja, the wild a...
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Plant cross-fertilization for production of dual-specific antibodies targeting both Ebola virus–like particles and HER2 protein in F1 plants
This study explores the cross-fertilization of transgenic tobacco plants to produce dual-specific monoclonal antibodies (m...
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BRN3A, a transcription factor, regulates the expression of genes involved in biological processes shaping the HPV induced cervical cancer
Cervical cancer is the fourth most common cancer worldwide in females. This occurs primarily due to the infection of high-...
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The diverse landscape of RNA modifications in cancer development and progression
RNA modifications, a central aspect of epitranscriptomics, add a regulatory layer to gene expression by modifying RNA func...
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A combination of upstream alleles involved in rice heading hastens natural long-day responses
The female parental line Jinbuol (JBO, early heading) and two recombinant isogenic lines, JSRIL1 and JSRIL2, have been sho...
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The facilitated osteogenic differentiation by extracellular proline treatment in in vitro cell cultivation using MC3T3E1 and hPDLF
Proline is a major substrate in collagen biosynthesis and is required for collagen molecule formations. However, detailed ...
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Potential role of ARG1 c.57G > A variant in Argininemia
Argininemia (OMIM: 207800), as well as arginase deficiency, a disorder of the urea cycle caused by deficiency of arginase ...
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Identification of genetic loci enriched in obese or lean T2D cases in the Korean population
Obesity causes many complex diseases including type 2 diabetes (T2D). Obesity increases the risk of T2D in Europeans, but ...
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miR-214-3p inhibits LPS-induced macrophage inflammation and attenuates the progression of dry eye syndrome by regulating ferroptosis in cells
Dry eye disease (DED) is an ocular illness caused by insufficient tear secretion or poor tear quality, and inflammation is...
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Baihu Jia Renshen Decoction may improve skeletal muscle and adipose tissue functions of type I diabetic rats by affecting pancreatic β-cell function
Baihu Jia Renshen Decoction (BJRD) is used for diabetes mellitus (DM) management in clinics. To elucidate the potential me...
Genes & Genomics
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Population genetics analysis based on mitochondrial cytochrome c oxidase subunit I (CO1) gene sequences of Cottus koreanus in South Korea
The freshwater sculpin Cottus koreanus is endemic to the Korean Peninsula and has a fluvial life history. However, its pop...
Genes & Genomics
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Identification and expression analysis of the SPL gene family during flower bud differentiation in Rhododendron molle
The family of SQUAMOSA promoter binding protein-like (SPL) transcription factors is essential for regulating plant growth ...
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Digital insights into Pseudomonas aeruginosa PBH03: in-silico analysis for genomic toolbox and unraveling cues for heavy metal bioremediation
The genomes of publicly available electroactive Pseudomonas aeruginosa strains are currently limited to in-silico analyses...
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Propylparaben-induced endoplasmic reticulum stress triggers G2/M phase cell cycle arrest and initiates caspase-3-dependent apoptosis in human lung cells
Propylparaben (PrP) is commonly used as an antimicrobial agent in food, cosmetics, and pharmaceuticals. While recent studi...
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Downregulated CDH3 is correlated with a better prognosis for LUAD and decreases proliferation and migration of lung cancer cells
CDH3 is a glycoprotein with a single-span transmembrane domain that mediates cell-to-cell adhesion. Abnormal expression of...
Genes & Genomics
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Integration of single-cell transcriptomics and epigenetic analysis reveals enhancer-controlled TIMP1 as a regulator of ferroptosis in colorectal cancer
Ferroptosis is an iron-dependent non-apoptotic programmed cell death. However, the regulatory mechanism of ferroptosis in ...
Genes & Genomics
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A review on gene regulatory network reconstruction algorithms based on single cell RNA sequencing
Understanding gene regulatory networks (GRNs) is essential for unraveling the molecular mechanisms governing cellular beha...
Genes & Genomics
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SRSF7 is a promising prognostic biomarker in hepatocellular carcinoma and is associated with immune infiltration
Previous studies indicate that the splicing process, regulated by the cellular machinery of tumors (spliceosome), undergoe...
Genes & Genomics
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Characterization and comparative analysis of the complete organelle genomes of three red macroalgae species (Neoporphyra dentata, Neoporphyra seriata, and Neopyropia yezoensis) and development of molecular makers for their identification
Many species of red algae belonging to the phylum Rhodophyta are consumed by humans as raw materials for nutrition and med...
Genes & Genomics
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Disclosing the hidden nucleotide sequences: a journey into DNA barcoding of raptor species in public repositories
In nucleotide public repositories, studies discovered data errors which resulted in incorrect species identification of se...
Genes & Genomics
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Feature selection for effective prediction of SARS-COV-2 using machine learning
With rise in variants of SARS-CoV-2, it is necessary to classify the emerging SARS-CoV-2 for early detection and thereby r...
Genes & Genomics
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Comparative transcriptome analysis of two contrasting genotypes provides new insights into the drought response mechanism in pigeon pea (Cajanus cajan L. Millsp.)
Despite plant's ability to adapt and withstand challenging environments, drought poses a severe threat to their growth...
Genes & Genomics
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DNA methylation of GDF-9 and GHR genes as epigenetic regulator of milk production in Egyptian Zaraibi goat
DNA methylation is an epigenetic mechanism that takes place at gene promoters and a potent epigenetic marker to regulate g...
Genes & Genomics
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Skin benefits of postbiotics derived from Micrococcus luteus derived from human skin: an untapped potential for dermatological health
The skin microbiome, a diverse community of microorganisms, plays a crucial role in maintaining skin health. Among these m...
Genes & Genomics
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Single-cell transcriptomic analysis reveals transcriptional and cell subpopulation differences between human and pig immune cells
The pig is a promising donor candidate for xenotransplantation. Understanding the differences between human and swine immu...
Genes & Genomics
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Mycobacterium tuberculosis virulence protein ESAT-6 influences M1/M2 polarization and macrophage apoptosis to regulate tuberculosis progression
Tuberculosis (TB) is an infectious disease caused by infection with Mycobacterium tuberculosis (Mtb), and it remains one o...
Genes & Genomics
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SUZ12 inhibition attenuates cell proliferation of glioblastoma via post-translational regulation of CDKN1B
Human gliomas are aggressive brain tumors characterized by uncontrolled cell proliferation. Differential expression of Pol...
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