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Enhanced Anticancer Efficacy of Selenium Nanoparticles Encapsulated in Niosomes: A Novel Therapeutic Strategy
Enhanced Anticancer Efficacy of Selenium Nanoparticles Encapsulated in Niosomes: A Novel Therapeutic Strategy
Oral squamous cell carcinoma persists as a formidable global health challenge, characterized by notably high morbidity and...
Heavy Metal Exposure and its Health Implications: A Comprehensive Review
Heavy Metal Exposure and its Health Implications: A Comprehensive Review
Toxic metal exposure is a global health concern with serious implications for human well-being. Metals such as lead, mercu...
Association of rs11640851, rs8052394 and rs11076161 Polymorphisms with the Risk of Developing Breast Cancer: A Haplotype-Based Case-Control Study and in Silico Analysis
Association of rs11640851, rs8052394 and rs11076161 Polymorphisms with the Risk of Developing Breast Cancer: A Haplotype-Based Case-Control Study and in Silico Analysis
Metallothionein 1 A (MT1a) is involved in many pathological conditions associated with antioxidant defense and de...
Carcinogenic Link to Diabetes, Obesity and Atherosclerosis—A Focus on Differently Programmed Cholesterol Homeostasis
Carcinogenic Link to Diabetes, Obesity and Atherosclerosis—A Focus on Differently Programmed Cholesterol Homeostasis
Diabetes and obesity are the known partners of metabolic syndrome having co-morbidities of atherosclerosis and hypercholes...
The Role of L-Arginine Metabolism and Endogenous Dimethylarginine in Chronic Venous Insufficiency
The Role of L-Arginine Metabolism and Endogenous Dimethylarginine in Chronic Venous Insufficiency
Our knowledge about the possible effects of inflammatory factors, oxidative stress, and coagulation factors on the venous ...
Combined Effects of Lipoic Acid and Dimercaptosuccinic Acid in Improving Lead-Induced Alterations on Glucose Metabolism, Energy Metabolism and Tissue Histology
Combined Effects of Lipoic Acid and Dimercaptosuccinic Acid in Improving Lead-Induced Alterations on Glucose Metabolism, Energy Metabolism and Tissue Histology
The research highlights the protective effects of DL-α-Lipoic acid (LA) at a dosage of 25 mg/kg body weight,...
Association Between Vitamin D Receptor Gene Polymorphism and Diabetic Nephropathy in Patients with Type 2 Diabetes Mellitus
Association Between Vitamin D Receptor Gene Polymorphism and Diabetic Nephropathy in Patients with Type 2 Diabetes Mellitus
This study investigates the link between low vitamin D (Vit D) levels, FokI polymorphism in the vitamin D receptor (VDR) g...
Coumarins at the Crossroads of Drug Development: Enzyme Modulation for Clinical Advances
Coumarins at the Crossroads of Drug Development: Enzyme Modulation for Clinical Advances
Coumarins, a diverse class of naturally occurring and synthetic compounds, have garnered significant attention in drug dev...
Genetic Determinants of Apoptosis Regulate Liver Cirrhosis Risk: The FAS/FASL Polymorphism Connection in Iraqi Population
Genetic Determinants of Apoptosis Regulate Liver Cirrhosis Risk: The FAS/FASL Polymorphism Connection in Iraqi Population
A number of chronic liver illnesses often culminate in liver cirrhosis. It is typically brought on by long-term liver cond...
Identification of Deleterious Missense Single Nucleotide Polymorphisms in Human Gene: An In Silico Study
Identification of Deleterious Missense Single Nucleotide Polymorphisms in Human Gene: An In Silico Study
Interleukin-2-inducible T-cell kinase (ITK), a mammalian non-receptor tyrosine kinase, shows the highest level of expressi...
Polygenic Risk Scores for Predicting Type 2 Diabetes Using Whole-Exome Sequencing and Global Screening Array
Polygenic Risk Scores for Predicting Type 2 Diabetes Using Whole-Exome Sequencing and Global Screening Array
This study investigated the predictability of type 2 diabetes (T2D) using genetic risk factors identified through Genome-w...
Exploring the Prognostic and Diagnostic Value of miR-497-5p and miR-17-5p in Breast Cancer: In Silico and Experimental Analysis
Exploring the Prognostic and Diagnostic Value of miR-497-5p and miR-17-5p in Breast Cancer: In Silico and Experimental Analysis
Breast cancer ranks as the most prevalent cancer worldwide. MicroRNAs (miRNAs) play dual roles as oncogenes and tumor supp...
Frequency and Associations of the Gilbert Syndrome (*28/*28) in Patients with Non–alcoholic Fatty Liver Disease
Frequency and Associations of the Gilbert Syndrome (*28/*28) in Patients with Non–alcoholic Fatty Liver Disease
Interrelationship of non-alcoholic fatty liver disease (NAFLD) with Gilbert syndrome (GS, homozygous UGT1A1*28/*28 or TA7/...
Genetic Variation in the Receptor for Advanced Glycation End Product (1704G > T) and Matrix Metalloproteinase-9 (-1562 C/T) in Type 2 Diabetic Patients with Nephropathy in Western Rajasthan
Genetic Variation in the Receptor for Advanced Glycation End Product (1704G > T) and Matrix Metalloproteinase-9 (-1562 C/T) in Type 2 Diabetic Patients with Nephropathy in Western Rajasthan
The receptor for Advanced Glycation End Products (RAGE) gene polymorphism influences matrix metalloproteinase 9 (MMP-9) le...
Therapeutic Potential of High Dose Vitamin C in Cancer: Mechanisms, Clinical Evidence and Future Directions
Therapeutic Potential of High Dose Vitamin C in Cancer: Mechanisms, Clinical Evidence and Future Directions
High-dose vitamin C (HDVC) has emerged as a potential adjunct for cancer treatment because of its selective toxicity again...
miR-30b-5p Promotes Medulloblastoma Cell Proliferation by Regulating Stem Cell Factors NANOG, BMI1, Tumor Suppressor Gene P53 and the Shh-Gli1 Pathway
miR-30b-5p Promotes Medulloblastoma Cell Proliferation by Regulating Stem Cell Factors NANOG, BMI1, Tumor Suppressor Gene P53 and the Shh-Gli1 Pathway
Medulloblastoma (MB), a malignant tumour arising in the brain, exhibits distinct microRNA expression patterns. One such mi...
Serum 17 Alpha-Hydroxyprogesterone Analysis- Performance Evaluation of Maglumi® X-8 Chemiluminescence Immunoassay
Serum 17 Alpha-Hydroxyprogesterone Analysis- Performance Evaluation of Maglumi® X-8 Chemiluminescence Immunoassay
Congenital Adrenal Hyperplasia (CAH) is primarily caused by 21-hydroxylase deficiency, leading to abnormal adrenal hormone...
Unveiling Hydrogen Sulfide: A New Frontier in Neuroprotection and Neuromodulation
Unveiling Hydrogen Sulfide: A New Frontier in Neuroprotection and Neuromodulation
Hydrogen sulfide (H2S), once recognized as a harmful gas, is now emerging as a very significant biological substance with ...
Investigation of Association of TYK2-P1104A Variant in Systemic Lupus Erythematosus Patients With or Without Tuberculosis
Investigation of Association of TYK2-P1104A Variant in Systemic Lupus Erythematosus Patients With or Without Tuberculosis
Systemic lupus erythematosus (SLE) is a complex disorder involving a hyperactive immune system. SLE is debilitating, with ...
Combination Therapy of Curcumin and Cisplatin Encapsulated in Niosome Nanoparticles for Enhanced Oral Cancer Treatment
Combination Therapy of Curcumin and Cisplatin Encapsulated in Niosome Nanoparticles for Enhanced Oral Cancer Treatment
Oral cavity cancer poses a significant health threat due to its aggressive nature and limited responsiveness to traditiona...
HDL or hs-CRP: The Prognostic Conundrum in Acute Coronary Syndrome
HDL or hs-CRP: The Prognostic Conundrum in Acute Coronary Syndrome
There is a dearth of information from research regarding the correlation between high density lipoprotein (HDL) and high-s...
Short-Chain Fatty Acids Ameliorates Lipid Profile, Oxidative Stress and Inflammation in Letrozole Induced Polycystic Ovary Syndrome Rat Model
Short-Chain Fatty Acids Ameliorates Lipid Profile, Oxidative Stress and Inflammation in Letrozole Induced Polycystic Ovary Syndrome Rat Model
Polycystic ovary syndrome (PCOS) is one of the most common metabolic-reproductive disorders affecting reproductive-age wom...
Occupational Exposure to Lead Increases Inflammation that Causes Cardiovascular Disease and Lowers Selenium levels
Occupational Exposure to Lead Increases Inflammation that Causes Cardiovascular Disease and Lowers Selenium levels
Lead is a hazardous heavy metal. It has serious health effects due to its unique physical and chemical properties. Lead po...
hsa-miR-885-5p As Post Transcription Regulator of Matrix metalloproteinase 9 in Tuberculous Meningitis
hsa-miR-885-5p As Post Transcription Regulator of Matrix metalloproteinase 9 in Tuberculous Meningitis
Matrix metalloproteinase 9 (MMP9) has a potent role in neuroinflammation in tuberculous meningitis (TBM). Recent researche...
A Review of Methionine and Cysteine: Their Roles as Sinks for Reactive Oxygen and Nitrogen Species, Including Bioinformatic Analysis of Their Percent Compositions in Metabolic Proteins
A Review of Methionine and Cysteine: Their Roles as Sinks for Reactive Oxygen and Nitrogen Species, Including Bioinformatic Analysis of Their Percent Compositions in Metabolic Proteins
This review focuses on the roles of the two primary sulfur-containing amino acids, cysteine and methionine, in regulating ...
Current Paradigms in Understanding Neuron Fluctuations, Factors, Regulation, Pathophysiology of Epilepsy: Advancements in Diagnosis, Treatment and Management—An Update
Current Paradigms in Understanding Neuron Fluctuations, Factors, Regulation, Pathophysiology of Epilepsy: Advancements in Diagnosis, Treatment and Management—An Update
Epilepsy has been attributed to be a most common universal brain neurological disorder afflicting more than 50 million peo...
Transcriptional Scenario of Altered Glycosylation in HPV-Associated Cervical Cancer
Transcriptional Scenario of Altered Glycosylation in HPV-Associated Cervical Cancer
Cervical cancer is one of the leading malignancies in women in India, with a high mortality rate and no available targeted...
Pyrethroid Levels Amplify Asthma Severity in Children via Elevating Eosinophils, IgE, and Compromising Lung Function
Pyrethroid Levels Amplify Asthma Severity in Children via Elevating Eosinophils, IgE, and Compromising Lung Function
Pesticide exposure in children, particularly through inhalation, is known to exacerbate asthma and contribute to its devel...
The Reference Interval Values of Biochemical Parameters in Iranian Kurdish Adults: Results from Non-communicable Diseases of Ravansar Cohort
The Reference Interval Values of Biochemical Parameters in Iranian Kurdish Adults: Results from Non-communicable Diseases of Ravansar Cohort
This study aimed to establish age- and sex-specific biochemical parameters Reference intervals (RIs) in a healthy adult Ku...
Tissue Inhibitor of Metalloproteinase 2 (TIMP 2) Promotor 418 G > C Polymorphism in Non-alcoholic Fatty Liver Disease (NAFLD) Patients of Eastern States of India
Tissue Inhibitor of Metalloproteinase 2 (TIMP 2) Promotor 418 G > C Polymorphism in Non-alcoholic Fatty Liver Disease (NAFLD) Patients of Eastern States of India
Tissue Inhibitor of Metalloproteinases 2 (TIMPs) prevent breakdown of extracellular matrix and is known for its role in fi...
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