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miR-30b-5p Promotes Medulloblastoma Cell Proliferation by Regulating Stem Cell Factors NANOG, BMI1, Tumor Suppressor Gene P53 and the Shh-Gli1 Pathway
miR-30b-5p Promotes Medulloblastoma Cell Proliferation by Regulating Stem Cell Factors NANOG, BMI1, Tumor Suppressor Gene P53 and the Shh-Gli1 Pathway
Medulloblastoma (MB), a malignant tumour arising in the brain, exhibits distinct microRNA expression patterns. One such mi...
Serum 17 Alpha-Hydroxyprogesterone Analysis- Performance Evaluation of Maglumi® X-8 Chemiluminescence Immunoassay
Serum 17 Alpha-Hydroxyprogesterone Analysis- Performance Evaluation of Maglumi® X-8 Chemiluminescence Immunoassay
Congenital Adrenal Hyperplasia (CAH) is primarily caused by 21-hydroxylase deficiency, leading to abnormal adrenal hormone...
Unveiling Hydrogen Sulfide: A New Frontier in Neuroprotection and Neuromodulation
Unveiling Hydrogen Sulfide: A New Frontier in Neuroprotection and Neuromodulation
Hydrogen sulfide (H2S), once recognized as a harmful gas, is now emerging as a very significant biological substance with ...
Investigation of Association of TYK2-P1104A Variant in Systemic Lupus Erythematosus Patients With or Without Tuberculosis
Investigation of Association of TYK2-P1104A Variant in Systemic Lupus Erythematosus Patients With or Without Tuberculosis
Systemic lupus erythematosus (SLE) is a complex disorder involving a hyperactive immune system. SLE is debilitating, with ...
Combination Therapy of Curcumin and Cisplatin Encapsulated in Niosome Nanoparticles for Enhanced Oral Cancer Treatment
Combination Therapy of Curcumin and Cisplatin Encapsulated in Niosome Nanoparticles for Enhanced Oral Cancer Treatment
Oral cavity cancer poses a significant health threat due to its aggressive nature and limited responsiveness to traditiona...
HDL or hs-CRP: The Prognostic Conundrum in Acute Coronary Syndrome
HDL or hs-CRP: The Prognostic Conundrum in Acute Coronary Syndrome
There is a dearth of information from research regarding the correlation between high density lipoprotein (HDL) and high-s...
Short-Chain Fatty Acids Ameliorates Lipid Profile, Oxidative Stress and Inflammation in Letrozole Induced Polycystic Ovary Syndrome Rat Model
Short-Chain Fatty Acids Ameliorates Lipid Profile, Oxidative Stress and Inflammation in Letrozole Induced Polycystic Ovary Syndrome Rat Model
Polycystic ovary syndrome (PCOS) is one of the most common metabolic-reproductive disorders affecting reproductive-age wom...
Occupational Exposure to Lead Increases Inflammation that Causes Cardiovascular Disease and Lowers Selenium levels
Occupational Exposure to Lead Increases Inflammation that Causes Cardiovascular Disease and Lowers Selenium levels
Lead is a hazardous heavy metal. It has serious health effects due to its unique physical and chemical properties. Lead po...
hsa-miR-885-5p As Post Transcription Regulator of Matrix metalloproteinase 9 in Tuberculous Meningitis
hsa-miR-885-5p As Post Transcription Regulator of Matrix metalloproteinase 9 in Tuberculous Meningitis
Matrix metalloproteinase 9 (MMP9) has a potent role in neuroinflammation in tuberculous meningitis (TBM). Recent researche...
A Review of Methionine and Cysteine: Their Roles as Sinks for Reactive Oxygen and Nitrogen Species, Including Bioinformatic Analysis of Their Percent Compositions in Metabolic Proteins
A Review of Methionine and Cysteine: Their Roles as Sinks for Reactive Oxygen and Nitrogen Species, Including Bioinformatic Analysis of Their Percent Compositions in Metabolic Proteins
This review focuses on the roles of the two primary sulfur-containing amino acids, cysteine and methionine, in regulating ...
Current Paradigms in Understanding Neuron Fluctuations, Factors, Regulation, Pathophysiology of Epilepsy: Advancements in Diagnosis, Treatment and Management—An Update
Current Paradigms in Understanding Neuron Fluctuations, Factors, Regulation, Pathophysiology of Epilepsy: Advancements in Diagnosis, Treatment and Management—An Update
Epilepsy has been attributed to be a most common universal brain neurological disorder afflicting more than 50 million peo...
Transcriptional Scenario of Altered Glycosylation in HPV-Associated Cervical Cancer
Transcriptional Scenario of Altered Glycosylation in HPV-Associated Cervical Cancer
Cervical cancer is one of the leading malignancies in women in India, with a high mortality rate and no available targeted...
Pyrethroid Levels Amplify Asthma Severity in Children via Elevating Eosinophils, IgE, and Compromising Lung Function
Pyrethroid Levels Amplify Asthma Severity in Children via Elevating Eosinophils, IgE, and Compromising Lung Function
Pesticide exposure in children, particularly through inhalation, is known to exacerbate asthma and contribute to its devel...
The Reference Interval Values of Biochemical Parameters in Iranian Kurdish Adults: Results from Non-communicable Diseases of Ravansar Cohort
The Reference Interval Values of Biochemical Parameters in Iranian Kurdish Adults: Results from Non-communicable Diseases of Ravansar Cohort
This study aimed to establish age- and sex-specific biochemical parameters Reference intervals (RIs) in a healthy adult Ku...
Tissue Inhibitor of Metalloproteinase 2 (TIMP 2) Promotor 418 G > C Polymorphism in Non-alcoholic Fatty Liver Disease (NAFLD) Patients of Eastern States of India
Tissue Inhibitor of Metalloproteinase 2 (TIMP 2) Promotor 418 G > C Polymorphism in Non-alcoholic Fatty Liver Disease (NAFLD) Patients of Eastern States of India
Tissue Inhibitor of Metalloproteinases 2 (TIMPs) prevent breakdown of extracellular matrix and is known for its role in fi...
Neural Cell Adhesion Molecule-1 Gene Polymorphism Increases the Risk of Cognitive Dysfunction in Schizophrenia Spectrum Disorder
Neural Cell Adhesion Molecule-1 Gene Polymorphism Increases the Risk of Cognitive Dysfunction in Schizophrenia Spectrum Disorder
Neural cell adhesion molecule-1 (NCAM-1), a marker of synaptic plasticity is reported to be altered and associated with co...
Insights for miR-9, miR-21, and miR-34a Expression Levels and Their Cross-Talk with TNF-α, IL-1β, and Nrf2 Levels in Diabetic Nephropathy Patients
Insights for miR-9, miR-21, and miR-34a Expression Levels and Their Cross-Talk with TNF-α, IL-1β, and Nrf2 Levels in Diabetic Nephropathy Patients
Oxidative stress and inflammatory mediators are considered the main culprits responsible for orchestrating diabetic compli...
Differential Impact of VNTR Polymorphism in the CBS Gene on Gastric and Breast Cancers Risk
Differential Impact of VNTR Polymorphism in the CBS Gene on Gastric and Breast Cancers Risk
The cystathionine beta-synthase (CBS) gene plays a critical role in numerous physiological processes, including cellular p...
Sweet Bell Pepper: A Focus on Its Nutritional Qualities and Illness-Alleviated Properties
Sweet Bell Pepper: A Focus on Its Nutritional Qualities and Illness-Alleviated Properties
Sweet bell pepper (SBP, Capsicum annuum L.) can be employed as a spice in many dishes and may also be eaten as a delicious...
Asprosin is a Reliable Predictor of Osteoporosis in Type 2 Diabetic Postmenopausal Women: A Case–Control Study
Asprosin is a Reliable Predictor of Osteoporosis in Type 2 Diabetic Postmenopausal Women: A Case–Control Study
The study evaluates Asprosin's value in diabetic postmenopausal women, examining its reliability as a predictor for os...
The Field of Regulated Cell Death Biology Requires Umbrella Reviews
The Field of Regulated Cell Death Biology Requires Umbrella Reviews
Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, et al. Molecular mechanisms of cell death: recommendati...
SCN1A Genetic Alterations and Oxidative Stress in Idiopathic Generalized Epilepsy Patients: A Causative Analysis in Refractory Cases
SCN1A Genetic Alterations and Oxidative Stress in Idiopathic Generalized Epilepsy Patients: A Causative Analysis in Refractory Cases
Single Nucleotide Polymorphisms (SNPs) have found it be associated with drug resistance in epilepsy. The purpose of this s...
Methylenetetrahydrofolate Reductase Gene Polymorphism as a Risk Factor for Coronary Artery Disease
Methylenetetrahydrofolate Reductase Gene Polymorphism as a Risk Factor for Coronary Artery Disease
Hyperhomocysteinemia (HHcy) is one of the factors contributing to the pathogenesis of coronary artery disease (CAD). Besid...
Detection of HbD Punjab Trait in Saurashtra Region of Gujarat by HPLC Method
Detection of HbD Punjab Trait in Saurashtra Region of Gujarat by HPLC Method
The HbD Punjab trait is a less common hemoglobin variant in the Saurashtra region of Gujarat. This patient presented to th...
Redefining the Reference Interval and Cut-Off Values of the Hematological and Biochemical Parameters and Deriving a Sensitive Predictive Marker for Crisis Events in Sickle Cell Disease
Redefining the Reference Interval and Cut-Off Values of the Hematological and Biochemical Parameters and Deriving a Sensitive Predictive Marker for Crisis Events in Sickle Cell Disease
The heterogeneity in clinical presentations in sickle cell disease (SCD) alters between crisis and steady state phases. Co...
Diagnostic Utility of Serum Ferritin in Identifying Liver Fibrosis in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD): A Cross-Sectional Study Using National Health and Nutrition Examination Survey (NHANES—2017–2020) Data
Diagnostic Utility of Serum Ferritin in Identifying Liver Fibrosis in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD): A Cross-Sectional Study Using National Health and Nutrition Examination Survey (NHANES—2017–2020) Data
Non-alcoholic fatty liver disease (NAFLD) is one of the major causes of chronic liver disease worldwide. There are conflic...
Potential Effect of Extracellular Vesicles in Clinical Settings of Lymphoma
Potential Effect of Extracellular Vesicles in Clinical Settings of Lymphoma
Liquid biopsy is gaining importance in oncology in the age of precision medicine. Extracellular vesicles (EVs), among othe...
Obesity: An Impact with Cardiovascular and Cerebrovascular Diseases
Obesity: An Impact with Cardiovascular and Cerebrovascular Diseases
The authors sought to correlate the complex sequel of obesity with various parameters known to develop metabolic syndrome ...
Artificial Intelligence in Clinical Chemistry: Dawn of a New Era?
Artificial Intelligence in Clinical Chemistry: Dawn of a New Era?
The emergence and integration of artificial intelligence (AI) into various facets of ...
Correlation of Diabetes Related Factors with Vitamin D and Immunological Parameters in T2DM Kashmiri Population
Correlation of Diabetes Related Factors with Vitamin D and Immunological Parameters in T2DM Kashmiri Population
In this study, the role of inflammatory biomarkers and vitamin D in Type 2 diabetes mellitus (T2DM) and their correlation ...
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