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Interleukin-17: A pleiotropic cytokine implicated in inflammatory, infectious, and malignant disorders
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The activin-follistatin system: Key regulator of kidney development, regeneration, inflammation, and fibrosis
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Nuclear translocation of RON receptor tyrosine kinase. New mechanistic and functional insights
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LC3B: A microtubule-associated protein influences disease progression and prognosis
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Cytokine signalling in formation of neutrophil extracellular traps: Implications for health and diseases
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Cytokine modulation and immunoregulation of uterine NK cells in pregnancy disorders
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Granulocyte macrophage colony stimulating factor in virus-host interactions and its implication for immunotherapy
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Epithelial-to-mesenchymal transition transcription factors: New strategies for mesenchymal tissue regeneration
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Forgetting COVID-19 – Introduction to the special issue
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The immunopathogenesis of a cytokine storm: The key mechanisms underlying severe COVID-19
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Interferon-I modulation and natural products: Unraveling mechanisms and therapeutic potential in severe COVID-19
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Inflamm-ageing: How cytokines and nutrition shape the trajectory of ageing
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The intersection of microbiome and autoimmunity in long COVID-19: Current insights and future directions
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Mechanisms coupling the mTOR pathway to chronic obstructive pulmonary disease (COPD) pathogenesis
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The Yin and Yang of TLR4 in COVID-19
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From immune activation to disease progression: Unraveling the complex role of Serum Amyloid A proteins
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Decoding the Neuroimmune Axis in Colorectal Cancer: From Neural Circuitry to Therapeutic Innovation
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COVID-19: from emerging variants to vaccination
COVID-19: from emerging variants to vaccination
The vigorous spread of SARS-CoV-2 resulted in the rapid infection of millions of people worldwide and devastation of not o...
Harnessing the Potential of CD40 Agonism in Cancer Therapy
Harnessing the Potential of CD40 Agonism in Cancer Therapy
Dr. Chi Yan is an Assistant Professor in the Department of Pharmacology at Vanderbilt University School of Medicine, Nashv...
Radiation-targeted immunotherapy: a new perspective in cancer radiotherapy
Radiation-targeted immunotherapy: a new perspective in cancer radiotherapy
Radiation therapy is widely used in cancer treatment[1], [2]. Its mechanism is to destroy the DNA of cancer cells through ...
The impact of COVID-19 on cancer patients
The impact of COVID-19 on cancer patients
In December 2019, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a novel coronavirus causing Coronavirus di...
An emerging paradigm of CXCL12 involvement in the metastatic cascade
An emerging paradigm of CXCL12 involvement in the metastatic cascade
George S. Karagiannis, D.V.M, Ph.D. is an assistant professor in the Department of Microbiology and Immunology at the Albe...
Progranulinopathy: A Diverse Realm of Disorders Linked to Progranulin Imbalances
Progranulinopathy: A Diverse Realm of Disorders Linked to Progranulin Imbalances
Progranulin (PGRN), also known as granulin–epithelin precursor (GEP), proepithelin, acrogranin, and GP88/PC-cell derived g...
Immunosuppressive Tumor Microenvironment and Uterine Fibroids:Role in Collagen Synthesis
Immunosuppressive Tumor Microenvironment and Uterine Fibroids:Role in Collagen Synthesis
Uterine fibroids (UF), also known as leiomyoma, is a benign uterine tumor with an unclear etiology that predominately affe...
CDK4/6 inhibition in hormone receptor-positive/HER2-negative breast cancer: biological and clinical aspects
CDK4/6 inhibition in hormone receptor-positive/HER2-negative breast cancer: biological and clinical aspects
Andrea Pretta is a MD specialized in Medical Oncology and a Researcher He works in the Medical Oncology Department at the ...
Mechanisms of NLRP3 inflammasome activation and the development of peptide inhibitors
Mechanisms of NLRP3 inflammasome activation and the development of peptide inhibitors
Dr. Bin Di, Ph.D. is a professor of pharmaceutical analysis and vice-dean of School of Pharmacy in the China Pharmaceutica...
The Odyssey of cGAS: from Cytosol to Nucleus
The Odyssey of cGAS: from Cytosol to Nucleus
Dr. Li is an Associate Professor at Tulane University, New Orleans, LA, USA. He received a Ph.D. from Wuhan University in ...
Extracellular Vesicles in Cardiovascular Diseases: From Pathophysiology to Diagnosis and Therapy
Extracellular Vesicles in Cardiovascular Diseases: From Pathophysiology to Diagnosis and Therapy
Extracellular vesicles (EVs) are heterogeneous cell-derived lipid-bilayer membranous nanoparticles serving as intercellula...
Bioengineering strategies to enhance the interleukin-18 bioactivity in the modern toolbox of cancer immunotherapy
Bioengineering strategies to enhance the interleukin-18 bioactivity in the modern toolbox of cancer immunotherapy
The collaboration of immunology and oncology for cancer treatment has experienced revolutionary development during the rec...