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Automatic detection of Cryptosporidium in optical microscopy images using YOLOv5x: a comparative study
Automatic detection of Cryptosporidium in optical microscopy images using YOLOv5x: a comparative study
Here, a machine learning tool (YOLOv5) enables the detection of Cryptosporidium microorganisms using optical and phase con...
LncRNAs: the good, the bad, and the unknown
LncRNAs: the good, the bad, and the unknown
Long non-coding RNAs (lncRNAs) are significant contributors in maintaining genomic integrity through epigenetic regulation...
The G protein-coupled receptor GPRC5A—a phorbol ester and retinoic acid-induced orphan receptor with roles in cancer, inflammation, and immunity
The G protein-coupled receptor GPRC5A—a phorbol ester and retinoic acid-induced orphan receptor with roles in cancer, inflammation, and immunity
GPRC5A is the first member of a new class of orphan receptors coupled to G proteins, which also includes GPRC5B, GPRC5C, a...
Attention-based deep learning framework to recognize diabetes disease from cellular retinal images
Attention-based deep learning framework to recognize diabetes disease from cellular retinal images
A medical disorder known as diabetic retinopathy (DR) affects people who suffer from diabetes. Many people are visually im...
Comparative analysis of the effect of hypoxia in two different tumor cell models shows the differential involvement of PTEN control of proangiogenic pathways
Comparative analysis of the effect of hypoxia in two different tumor cell models shows the differential involvement of PTEN control of proangiogenic pathways
Hypoxia, low, non-physiological oxygen tension is a key regulator of tumor microenvironment, determining the pathological ...
NDUFA4 promotes the progression of head and neck paraganglioma by inhibiting ferroptosis
NDUFA4 promotes the progression of head and neck paraganglioma by inhibiting ferroptosis
NDUFA4 is a component of respiratory chain–oxidative phosphorylation pathway. NDUFA4 is highly expressed in tumor tissues,...
The effects of cetuximab and cisplatin anti-cancer drugs on the mechanical properties of the lung cancerous cells using atomic force microscope
The effects of cetuximab and cisplatin anti-cancer drugs on the mechanical properties of the lung cancerous cells using atomic force microscope
Each anti-cancer drug has special effects on the target cells. One of the most important reasons to recommend an anti-canc...
Nootkatone attenuates airway inflammation in asthmatic mice through repressing ROS-induced NLRP3 inflammasome activation
Nootkatone attenuates airway inflammation in asthmatic mice through repressing ROS-induced NLRP3 inflammasome activation
Nootkatone (NKT) exhibits potential pharmacological activities including anti-oxidation and anti-inflammation. Nevertheles...
Targeting PTGES/PGE2 axis enhances sensitivity of colorectal cancer cells to 5-fluorouracil
Targeting PTGES/PGE2 axis enhances sensitivity of colorectal cancer cells to 5-fluorouracil
Insensitivity and resistance to 5-fluorouracil (5FU) remain as major hurdles for effective and durable 5FU-based chemother...
Histone chaperone SSRP1 is required for apoptosis inhibition and mitochondrial function in HCC via transcriptional promotion of TRAP1
Histone chaperone SSRP1 is required for apoptosis inhibition and mitochondrial function in HCC via transcriptional promotion of TRAP1
Epigenetic regulation contributes to human health and disease, especially cancer, but the mechanisms of many epigenetic re...
Suppression of academics and school training in Iran during the “Woman, Life, Freedom” revolution
Suppression of academics and school training in Iran during the “Woman, Life, Freedom” revolution
For the past 6 months, there has been an ongoing revolution in Iran after the brutal death of Zhina (Mahsa) Amini in moral...
Serum pro-surfactant protein B is correlated with clinical properties in osteosarcoma patients
Serum pro-surfactant protein B is correlated with clinical properties in osteosarcoma patients
It is critical to find efficient non-invasive prognostic factor for osteosarcoma. In this study, we demonstrated that seru...
Effects of clopidogrel bisulfate on B16-F10 cells and tumor development in a murine model of melanoma
Effects of clopidogrel bisulfate on B16-F10 cells and tumor development in a murine model of melanoma
Summary Metastatic melanoma is a very aggressive skin cancer. Platelets are constituents of the tumor microenvironment and...
Dysregulation of insulin-like growth factor-1 signaling in postnatal bone elongation
Dysregulation of insulin-like growth factor-1 signaling in postnatal bone elongation
Insulin-like growth factor-1 (IGF-1) is a critical modulator of cell growth and survival, making it a central part of main...
Remembering the legacy of Professor Mohammad Hashemi: a pioneer in molecular genetic studies in southeast Iran (1965–2019)
Remembering the legacy of Professor Mohammad Hashemi: a pioneer in molecular genetic studies in southeast Iran (1965–2019)
Professor Mohammad Hashemi was a clinical biochemist and cancer genetic scientist. He has been chair and head of Departmen...
AKT1 participates in ferroptosis vulnerability by driving autophagic degradation of FTH1 in cisplatin-resistant ovarian cancer
AKT1 participates in ferroptosis vulnerability by driving autophagic degradation of FTH1 in cisplatin-resistant ovarian cancer
Resistance to cisplatin (DDP)-based chemotherapy is an important reason for the failure of ovarian cancer treatment. Howev...
Message from Dr. Philippe T. Georgel, Guest Editor for the Marshall University Collection, Brad D. Smith, President of Marshall University, and Dr. Anivandan Mukherjee, Provost of Marshall University
Message from Dr. Philippe T. Georgel, Guest Editor for the Marshall University Collection, Brad D. Smith, President of Marshall University, and Dr. Anivandan Mukherjee, Provost of Marshall University
Philippe T. Georgel, Brad D. Smith, and Avinandan Mukherjee. 2023. Message from Dr. Philippe T. Georgel, Guest Editor f...
Telomere biology and ribosome biogenesis: structural and functional interconnections
Telomere biology and ribosome biogenesis: structural and functional interconnections
Telomeres are nucleoprotein structures that play a pivotal role in the protection and maintenance of eukaryotic chromosome...
Mechanism of myocardial fibrosis regulation by IGF-1R in atrial fibrillation through the PI3K/Akt/FoxO3a pathway
Mechanism of myocardial fibrosis regulation by IGF-1R in atrial fibrillation through the PI3K/Akt/FoxO3a pathway
Atrial structural remodeling takes on a critical significance to the occurrence and maintenance of atrial fibrillation (AF...
Astrocyte-specific Ca2+ activity: Mechanisms of action, experimental tools, and roles in ethanol-induced dysfunction
Astrocyte-specific Ca2+ activity: Mechanisms of action, experimental tools, and roles in ethanol-induced dysfunction
Astrocytes are a subtype of non-neuronal glial cells that reside in the central nervous system. Astrocytes have extensive ...
Evaluation of biochemical profile and oxidative damage to lipids and proteins in patients with lysosomal acid lipase deficiency
Evaluation of biochemical profile and oxidative damage to lipids and proteins in patients with lysosomal acid lipase deficiency
Lysosomal acid lipase deficiency (LALD) is an inborn error of metabolism that lacks satisfactory treatment, which leads to...
Analysis of financial challenges faced by graduate students in Canada
Analysis of financial challenges faced by graduate students in Canada
Graduate students are vital to the creation of research and innovation in Canada. The National Graduate Student Finance Su...
Retraction: Profibrogenic phenotype in caveolin-1 deficiency via differential regulation of STAT-1/3 proteins
Retraction: Profibrogenic phenotype in caveolin-1 deficiency via differential regulation of STAT-1/3 proteins
© 2023 The Author(s). This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0), wh...
SARS-CoV-2 E protein-induced THP-1 pyroptosis is reversed by Ruscogenin
SARS-CoV-2 E protein-induced THP-1 pyroptosis is reversed by Ruscogenin
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an emerging pathogenic coronavirus, has been reported to cau...
High concentrations of fructose cause brain damage in mice
High concentrations of fructose cause brain damage in mice
Excessive fructose consumption is associated with the incidence of obesity and systemic inflammation, resulting in increas...
Mitogen- and stress-activated protein kinase (MSK1/2) regulated gene expression in normal and disease states
Mitogen- and stress-activated protein kinase (MSK1/2) regulated gene expression in normal and disease states
The mitogen- and stress-activated protein kinases (MSK) are epigenetic modifiers that regulate gene expression in normal a...
Structural features, intrinsic disorder, and modularity of a pyriform spidroin 1 core repetitive domain
Structural features, intrinsic disorder, and modularity of a pyriform spidroin 1 core repetitive domain
Orb-weaving spiders produce up to seven silk types, each with distinct biological roles, protein compositions, and mechani...
Retraction: Wnt5A regulates the expression of ROR2 tyrosine kinase receptor in ovarian cancer cells
Retraction: Wnt5A regulates the expression of ROR2 tyrosine kinase receptor in ovarian cancer cells
Hossein G., Arabzadeh S., Salehi-Dulabi Z., Dehghani-Ghobadi Z., Heidarian Y., Talebi-Juybari M. 2016. Wnt5A regulates the...
Retraction: MiR-204 suppresses cell proliferation and promotes apoptosis in ovarian granulosa cells via targeting TPT1 in polycystic ovary syndrome
Retraction: MiR-204 suppresses cell proliferation and promotes apoptosis in ovarian granulosa cells via targeting TPT1 in polycystic ovary syndrome
© 2023 The Biochemistry and Cell Biology Editors. This work is licensed under a Creative Commons Attribution 4.0 Internati...
ERCC6 plays a promoting role in the progression of non-small cell lung cancer
ERCC6 plays a promoting role in the progression of non-small cell lung cancer
Although excision repair cross-complementing group 6 (ERCC6) has been reported to be associated with lung cancer risk, the...
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