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SCI Abstract
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Lipoprotein (a) levels and clinical decision-making: data from a Mexican cohort at a tertiary medical institution
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The association between the uric acid-to-high-density lipoprotein cholesterol ratio and osteoarthritis risk in U.S. adults: a cross-sectional study based on NHANES 1999–2016
The uric acid-to-high-density lipoprotein cholesterol ratio (UHR) is an established biomarker for metabolic and inflammato...
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Inflammation mediates the relationship between cardiometabolic index and vulnerable plaque in patients with acute coronary syndrome
As a novel indicator reflecting metabolic status and visceral adiposity distribution, the cardiometabolic index (CMI) has ...
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Untargeted metabolomics and transcriptomics joint analysis of the effects of polystyrene nanoplastics on lipid metabolism in the mouse liver
Micro/nanoplastics (MNPs), as emerging environmental pollutants, are widely present in environments that are essential for...
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Combination of the glycated hemoglobin levels and prognostic nutritional index as a prognostic marker in patients with acute coronary syndrome and type 2 diabetes mellitus
Increased susceptibility to malnutrition and inadequate glycemic control are frequently observed in diabetic patients with...
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Lipoprotein-associated phospholipase A2 predicts cardiovascular death in patients on maintenance hemodialysis: a 7-year prospective cohort study
Cardiovascular diseases (CVD) is the leading cause of death among maintenance hemodialysis patients, with dyslipidemia bei...
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Unlocking the mysteries of VLDL: exploring its production, intracellular trafficking, and metabolism as therapeutic targets
Reducing circulating lipid levels is the centerpiece of strategies for preventing and treating atherosclerotic cardiovascu...
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The association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and suicidal ideation in adults: a population-based study in the United States
The ratio of non-high-density lipoprotein cholesterol (non-HDL-C) to high-density lipoprotein cholesterol (HDL-C) (NHHR) s...
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Lipid alterations play a role in the integration of PD-1/PD-L1 inhibitors and anlotinib for the treatment of advanced non–small-cell lung cancer
Studies have shown that integrating anlotinib with programmed death 1 (PD-1)/programmed death-ligand 1 (PD-L1) inhibitors ...
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Establishment and validation of early prediction model for hypertriglyceridemic severe acute pancreatitis
The prevalence of hypertriglyceridaemia-induced acute pancreatitis (HTG-AP) is increasing due to improvements in living st...
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Comprehensive characterization of adipogenesis-related genes in colorectal cancer for clinical significance and immunogenomic landscape analyses
Colorectal cancer (CRC) is a major global health concern, necessitating the identification of biomarkers and molecular sub...
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High dietary intake of unsaturated fatty acids is associated with improved insulin resistance – a cross-sectional study based on the NHANES database
A moderate intake of unsaturated fatty acids (UFA) is associated positively with improved insulin resistance. The aim of t...
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Targeted changes in blood lipids improves fibrosis in renal allografts
Chronic interstitial fibrosis is the primary barrier against the long-term survival of transplanted kidneys. Extending the...
Lipids In Health And Disease
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Mildly elevated serum bilirubin and its correlations with lipid levels among male patients undergoing health checkups
Bilirubin’s ability to lower lipid levels was confirmed by several studies, but those studies mainly focused on tota...
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Rotundic acid improves nonalcoholic steatohepatitis in mice by regulating glycolysis and the TLR4/AP1 signaling pathway
Steatosis and inflammation are the hallmarks of nonalcoholic steatohepatitis (NASH). Rotundic acid (RA) is among the key t...
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Discovery of a novel lipid metabolism-related gene signature to predict outcomes and the tumor immune microenvironment in gastric cancer by integrated analysis of single-cell and bulk RNA sequencing
Gastric cancer (GC) is a pressing global clinical issue, with few treatment options and a poor prognosis. The onset and sp...
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A comprehensive multiomics approach reveals that high levels of sphingolipids in cardiac cachexia adipose tissue are associated with inflammatory and fibrotic changes
Cardiac cachexia is a deadly consequence of advanced heart failure that is characterised by the dysregulation of adipose t...
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Association of cardiometabolic factors and insulin resistance surrogates with mortality in participants from the Korean Genome and Epidemiology Study
Simple biochemical and anthropometric measurements such as fasting blood glucose (FBG), triglycerides (TG), high-density l...
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Evaluating the efficacy and timing of blood purification modalities in early-stage hyperlipidemic acute pancreatitis treatment
Hypertriglyceridemia-induced acute pancreatitis (HTG-AP) is characterized by a violent cytokine storm-driven inflammation ...
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The ZJU index is associated with the risk of obstructive sleep apnea syndrome in Chinese middle-aged and older people: a cross-sectional study
The ZJU index, a novel calculation that combines body mass index, triglycerides, fasting blood glucose and the ratio of al...
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Associations of serum carotenoids with visceral adiposity index and lipid accumulation product: a cross-sectional study based on NHANES 2001–2006
Visceral adiposity index (VAI) and lipid accumulation product (LAP) are comprehensive indicators to evaluate visceral fat ...
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Correlation between dietary inflammation and mortality among hyperlipidemics
Although the the Dietary Inflammatory Index (DII) serves to be one of the reliable indicator for hyperlipidaemia, there is...
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Exploring the hypolipidemic effects of bergenin from Saxifraga melanocentra Franch: mechanistic insights and potential for hyperlipidemia treatment
The goal of this study was to explore the hypolipidemic effects of bergenin extracted from Saxifraga melanocentra Franch (...
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Puerarin ameliorates metabolic dysfunction-associated fatty liver disease by inhibiting ferroptosis and inflammation
Metabolic dysfunction-associated fatty liver disease (MAFLD) is frequently linked to type 2 diabetes mellitus (T2DM), and ...
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Ectopic and visceral fat deposition in aging, obesity, and idiopathic pulmonary fibrosis: an interconnected role
Idiopathic pulmonary fibrosis (IPF) is considered an age-related disease. Age-related changes, along with other factors su...
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Non-alcoholic fatty liver disease risk prediction model and health management strategies for older Chinese adults: a cross-sectional study
Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver condition that affects a quarter of the global adult p...
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Role of arachidonic acid metabolism in intervertebral disc degeneration: identification of potential biomarkers and therapeutic targets via multi-omics analysis and artificial intelligence strategies
Intervertebral disc degeneration (IVDD) is widely recognized as the primary etiological factor underlying low back pain, o...
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Altered fecal bile acid composition in active ulcerative colitis
Disturbed bile acid homeostasis associated with a rise of primary and a decline of secondary bile acids is a consistent fi...
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ACT001 Alleviates chronic kidney injury induced by a high-fat diet in mice through the GPR43/AMPK pathway
Roughly 10 -15% of global populace suffer from Chronic Kidney Disease(CKD). A major secondary disease that can progress to...
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Potential impact of high-density lipoprotein cholesterol in the postoperative outcomes of chronic subdural hematoma patients: multi-institutional study in Korea
Chronic subdural hematoma (CSDH) is a common clinical situation in neurosurgical practice, but the optimal treatment optio...
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