SCI Abstract

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Exploring the origin of the development: totipotent stem cells
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Editorial overview: 3Rs update: a new era in cellular identity and therapeutic plasticity
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Centromere regulation in the germline and early embryo
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Why and how paternal mitochondrial DNA gets cut out of the inheritance
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Dynamic three-dimensional epigenomic reorganization for the development of undifferentiated spermatogonia in mice
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Transcription-coupled repair: protecting genome across generations
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Genome instability in mammalian embryos implications for genome editing, development, and evolution
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Transcription-Export complex in neurodevelopmental disorders
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Genetic disruption of nonsense-mediated mRNA decay in neurodevelopmental disorders
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Evolution and ecology of commensal gut protists: recent advances
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Linking phenotype to genotype using comprehensive genomic comparisons
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Evolution of comparative transcriptomics: biological scales, phylogenetic spans, and modeling frameworks
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Polygenic prediction of human complex traits using ancient DNA
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Behavioral evolution by diverging cell type composition
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Human gut evolution: insights from stem cell models and single-cell genomics
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Evolutionary genetics meets ecological immunology: insights into the evolution of immune systems
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Editorial Overview: Developmental mechanisms patterning and evolution (2025)
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Beyond equilibrium: roles of RNAs in condensate control
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Genome folding by cohesin
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Rewiring cancer: 3D genome determinants of cancer hallmarks
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Recipes and ingredients for deep learning models of 3D genome folding
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Principles of long-range gene regulation
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Fine-tuned programming of placenta trophoblast determines optimal maternal–fetal nutrient allocation
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Recent insights into the in vitro culture systems for mammalian embryos
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Insights and Interventions in Age-Associated Inflammation
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Decoding N6-methyladenosine’s dynamic role in stem cell fate and early embryo development: insights into RNA–chromatin interactions
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Modeling forebrain regional development and connectivity by human brain organoids
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Editorial overview: Regaining architecture and cell cross-talk upon regeneration
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Exploring the connection between RNA splicing and intellectual disability
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Bridging spatial and temporal scales of developmental gene regulation
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