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Timing of gene expression alters susceptibility to aflatoxicosis: a heterogeneous spectrum of disease in response to a single universal agent
Timing of gene expression alters susceptibility to aflatoxicosis: a heterogeneous spectrum of disease in response to a single universal agent
Aflatoxins (AFs) and their metabolites are a group of universally abundant organic compounds produced by fungus species of...
Classification of patients with lithium-treated bipolar disorder based on gene expression: Dirichlet Bayesian network model
Classification of patients with lithium-treated bipolar disorder based on gene expression: Dirichlet Bayesian network model
The Dirichlet Bayesian network model employs score-based structural learning, improving the precise understanding of the B...
Towards personalized prostate cancer treatment with docetaxel in indonesia: a pharmacogenomics perspective
Towards personalized prostate cancer treatment with docetaxel in indonesia: a pharmacogenomics perspective
Prostate cancer remains a significant global health issue, ranking as a leading cause of cancer-related mortality in men, ...
Molecular mavericks: unveiling the matrix metalloproteinase gene’s role in ovarian cancer
Molecular mavericks: unveiling the matrix metalloproteinase gene’s role in ovarian cancer
Ovarian cancer continues to rate among the most lethal gynecological tumors, in part due to limited treatment options and ...
Unraveling the roles of BMS1, ZNF749 and miR-6726-5p in MODS progression via integrated multiomics and ML-based approach
Unraveling the roles of BMS1, ZNF749 and miR-6726-5p in MODS progression via integrated multiomics and ML-based approach
Multiple organ dysfunction syndrome (MODS) is a severe, life-threatening condition characterized by progressive dysfunctio...
Effect of oxidative stress-related genetic variants: “Explicating the role of reactive oxygen species influenced antioxidant gene polymorphism,” a risk stratification of type 2 diabetes mellitus-associated nephropathy: a systematic review
Effect of oxidative stress-related genetic variants: “Explicating the role of reactive oxygen species influenced antioxidant gene polymorphism,” a risk stratification of type 2 diabetes mellitus-associated nephropathy: a systematic review
Type 2 diabetes mellitus is believed to be associated with microvascular complications which include diabetic retinopathy,...
The study of the impact of additional chromosomal aberrations and c-MYC and BCR::ABL1 genes amplification on CML patient’s characteristics: relation to haematological parameters and patient outcome
The study of the impact of additional chromosomal aberrations and c-MYC and BCR::ABL1 genes amplification on CML patient’s characteristics: relation to haematological parameters and patient outcome
Chronic myeloid leukaemia is characterised by genetic instability which results in additional cytogenetic aberrations that...
Identification of the cuproptosis-related ceRNA network and risk model in acute ischemic stroke by integrated bioinformatics analysis
Identification of the cuproptosis-related ceRNA network and risk model in acute ischemic stroke by integrated bioinformatics analysis
Acute ischemic stroke (AIS) is one of the leading contributors to death and disability in adults. And cuproptosis is a nov...
B-lymphocyte-activating factor is a potential biomarker associated with susceptibility to Graves’ disease in Iraqi women
B-lymphocyte-activating factor is a potential biomarker associated with susceptibility to Graves’ disease in Iraqi women
B-lymphocyte-activating factor (BAFF) is a cytokine involved in regulating the development and maturation of B lymphocyte ...
Association of maternal genetic polymorphisms with fetal growth restriction syndrome in Russian pregnant women from Rostov region
Association of maternal genetic polymorphisms with fetal growth restriction syndrome in Russian pregnant women from Rostov region
Fetal growth restriction (FGR) is one of the main syndromes causing fetal morbidity and mortality. It was known to be asso...
Association of ABCA1 gene with Coronary Artery Disease (CAD): an overview
Association of ABCA1 gene with Coronary Artery Disease (CAD): an overview
This review is a summarized study on CAD, CVD, atherosclerosis, and its association with the ABCA1 gene. Only 13 clinical ...
Association of OXTR polymorphism (rs53576) with depression: a meta-analysis
Association of OXTR polymorphism (rs53576) with depression: a meta-analysis
Depression is a common psychiatric disorder that negatively affects mood and thoughts. Association studies of OXTR polymor...
Effect of Dioscorea extract on Bax and Bcl-2 gene expression in MCF-7 and HFF cell lines
Effect of Dioscorea extract on Bax and Bcl-2 gene expression in MCF-7 and HFF cell lines
In cancer cells, the balance between proliferation and apoptosis is disturbed. There is a direct relationship between gene...
Association of ADAM33 gene with COPD pathophysiology: a case–control study
Association of ADAM33 gene with COPD pathophysiology: a case–control study
Worldwide, Chronic Obstructive pulmonary disease (COPD) is a main cause of morbidity and mortality. Considering the global...
Effect of hydroxyurea on SP1, LIN28B, IGF2BP3, COL4A5, BCL2, gamma globin genes expression: an in vitro study
Effect of hydroxyurea on SP1, LIN28B, IGF2BP3, COL4A5, BCL2, gamma globin genes expression: an in vitro study
In some β-thalassemia intermedia patients, hydroxyurea (HU) increases hemoglobin and HbF levels. However, HUs’ ...
Integrative bioinformatics analysis of miRNA and mRNA expression profiles identified some potential biomarkers for breast cancer
Integrative bioinformatics analysis of miRNA and mRNA expression profiles identified some potential biomarkers for breast cancer
Breast cancer is a common cause of cancer death among women with a complex and heterogeneous picture in histological, mole...
Novel PPP1R21 mutation in a family with autosomal recessive neurodevelopmental disorder: results of genomics and molecular analysis
Novel PPP1R21 mutation in a family with autosomal recessive neurodevelopmental disorder: results of genomics and molecular analysis
Neurodevelopmental diseases are a group of disorders affecting the development of the nervous system and brain function. I...
A meta-analysis and review on genetic mapping of type 2 diabetes mellitus in Iraq
A meta-analysis and review on genetic mapping of type 2 diabetes mellitus in Iraq
The prevalence of type 2 diabetes mellitus (T2DM) has been increasing rapidly in Iraq over the past few decades. Identifyi...
A glance on Immunogenetics Laboratory: from the origins to the future
A glance on Immunogenetics Laboratory: from the origins to the future
Histocompatibility and Immunogenetics (H&I) laboratories have currently a significant relevance in clinical and re...
Metformin reduces the cellular DNA repair capacity and enhances the effect of curcumin on the induction of apoptosis in AGS gastric cancer cells
Metformin reduces the cellular DNA repair capacity and enhances the effect of curcumin on the induction of apoptosis in AGS gastric cancer cells
Cancer results from the accumulation of mutations in critical genes, such as DNA repair genes. But these genes are a doubl...
Molecular profiling of BRCA1 and BRCA2 genes in Turkish patients with early-onset breast cancer
Molecular profiling of BRCA1 and BRCA2 genes in Turkish patients with early-onset breast cancer
Early-onset breast cancer (EOBC) is a specific condition that affects women under the age of 45. BRCA pathogenic/likely pa...
Allelic variation in TUSC1 gene: rs1462218557 is associated with male infertility and azoospermia
Allelic variation in TUSC1 gene: rs1462218557 is associated with male infertility and azoospermia
Male infertility is rapidly growing, and single nucleotide polymorphism (SNP) association studies are of critical importan...
Expanding the genotype–phenotype correlations in Alport syndrome: novel mutations, digenic inheritance, and genetic modifiers
Expanding the genotype–phenotype correlations in Alport syndrome: novel mutations, digenic inheritance, and genetic modifiers
Alport syndrome (AS) is the second most prevalent genetic cause of kidney failure, behind autosomal-dominant polycystic ki...
The role of miRNA-29b1, MMP-2, MMP-9 mRNAs, and proteins in early diagnosis of HCC
The role of miRNA-29b1, MMP-2, MMP-9 mRNAs, and proteins in early diagnosis of HCC
Hepatocellular carcinoma (HCC) is a common, serious malignancy with a dismal prognosis. As HCC is frequently missed in its...
Higher incidence of co-expression of BCR-ABL fusion transcripts in an Eastern Indian population
Higher incidence of co-expression of BCR-ABL fusion transcripts in an Eastern Indian population
Chronic myeloid leukaemia (CML) is a haematopoietic stem cell disorder, caused by a balanced reciprocal translocation (t(9...
Investigating the importance of EGFR (− 216G/T), Exo1 (K589E) and LEP (− 2548G/A) gene polymorphisms with risk of lung cancer as potential diagnostic biomarker in Iranian population
Investigating the importance of EGFR (− 216G/T), Exo1 (K589E) and LEP (− 2548G/A) gene polymorphisms with risk of lung cancer as potential diagnostic biomarker in Iranian population
In Iran, lung cancer is the third most common type of cancer and its prevalence is increasing rapidly. Identification info...
First application of next-generation sequencing in four families with Wilson disease in Morocco
First application of next-generation sequencing in four families with Wilson disease in Morocco
Wilson disease is a rare autosomal recessive disorder characterized by toxic accumulation of copper in various organs, pri...
Genetic and metabolic aspects of non-alcoholic fatty liver disease (NAFLD) pathogenicity
Genetic and metabolic aspects of non-alcoholic fatty liver disease (NAFLD) pathogenicity
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease showing a rising prevalence globally. G...
Association of angiotensin-converting enzyme I/D polymorphism and apolipoprotein B with cardiometabolic abnormalities among young adults: a pilot study from Delhi
Association of angiotensin-converting enzyme I/D polymorphism and apolipoprotein B with cardiometabolic abnormalities among young adults: a pilot study from Delhi
Angiotensin-converting enzyme (ACE) gene polymorphism and elevated apolipoprotein B (apoB) are important risk factors for ...
Integrated structure model-based virtual screening approaches identified anti-cancer agents against prostate cancer by targeting MAOB protein
Integrated structure model-based virtual screening approaches identified anti-cancer agents against prostate cancer by targeting MAOB protein
Flavin monoamine oxidase gene encodes a protein (MAOB) that forms a part of the flavin monoamine oxidase family in the out...
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