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SCI Abstract
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The Pro-inflammatory Functions of Type 1 CD 8+ T Cells and Interleukin-17-producing Cluster of Differentiation 8+ T Cells are Exhausted by Cholesterol in Atherosclerosis
Background: CD8+ T cells have been found to accumulate in atherosclerotic plaques. However, the specific role of CD8+ T ce...
Iranian Journal Of Immunology
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Analysis of the Blood Levels of NK and NKT Cells in Patients with Severe SARS-CoV-2 Infection
Background: Clinical manifestations SARS-CoV-2 infection are variable, ranging from asymptomatic to pneumonia, and differe...
Iranian Journal Of Immunology
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Effects of Intrauterine Infusion of G-CSF and HCG on Peripheral Blood Treg and Pregnancy Outcome in Patients with Thin Endometrium Undergoing Frozen-thawed Embryo Transfer
Background: Patients with thin endometrium undergoing frozen-thawed embryo transfer often encounter challenges with pregna...
Iranian Journal Of Immunology
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Blood Cytokine Profile in Breast Cancer: Focusing on Differences among Molecular Subtypes
Background: Breast cancer is the leading cause of cancer-related deaths in women. Cytokines have been linked to various ca...
Iranian Journal Of Immunology
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Design and Cytotoxicity Evaluation of a Cancer-targeting Immunotoxin Based on a Camelid Nanobody-PE Fusion Protein
Background: Developing effective targeted treatment approaches to overcome drug resistance remains a crucial goal in cance...
Iranian Journal Of Immunology
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Evaluation of Metastasis Inhibition by ABD-IL-2 Compared to Human IL-2 in a Breast Cancer Mouse Model
Background: Interleukin-2 (IL-2) is a well-known cytokine that plays a crucial role in stimulating immune cells, including...
Iranian Journal Of Immunology
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Antitumor Activity and Immunostimulant Properties of Liposomes Containing Rosemary Extract on a Mouse Model of Colorectal Cancer
Background: Rosemary (Ros) is a member of the Lamiaceae family known for its antitumor properties. However, its low water ...
Iranian Journal Of Immunology
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Gamma-delta T Cells in Bladder Cancer Draining Lymph Nodes
Background: Gamma-delta (γδ) T cells are a distinct subset of T cells with a receptor composed of γ and δ chains. Their ab...
Iranian Journal Of Immunology
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Human Umbilical Cord Mesenchymal Stem Cells and Their Extracellular Vesicles Modulate Pro- and Anti-Inflammatory Cytokines in Ligature-induced Periodontitis
Background: Periodontitis is a persistent inflammatory condition that impacts the tissues supporting the teeth, ultimately...
Iranian Journal Of Immunology
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Evaluation of mRNA Expressions of TOX and NR4As in CD8+ T cells in Acute Leukemia
Background: Thymocyte selection-associated high mobility group box protein (TOX) and members of the nuclear receptor 4A (N...
Iranian Journal Of Immunology
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Rescue of HLH with T and B Lymphocyte Involvement Due to Epstein-Barr Virus by PD-1 Inhibitor/Ruxolitinib and Rituximab Combination Regimens: A Case Report
Hemophagocytic lymphohistiocytosis (HLH) is a fatal clinical syndrome. The most common cause of secondary HLH is Epstein-B...
Iranian Journal Of Immunology
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High-free Fatty Acid Treatment Induced Anti-inflammatory Changes in a Natural Killer (NK) Cell Line
Background: Natural killer (NK) cells play a role in the pathogenesis of various metabolic diseases related to obesity. Wh...
Iranian Journal Of Immunology
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Antibody Production After COVID-19 Vaccination in Patients with Inborn Errors of Immunity
Background: Few studies have evaluated COVID-19 vaccine efficacy in patients with Inborn errors of immunity (IEI).Objectiv...
Iranian Journal Of Immunology
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Behaviors of Human T cells in SARS-CoV-2 Infection: Lessons and Tips
Cell-mediated immunity (CMI) is crucial in controlling the highly aggressive and progressive SARS-CoV-2 infection. Despite...
Iranian Journal Of Immunology
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Elevated HSP70 and HSP90 as Predictive Markers of Immune Activation and Lung Injury in SARS-COV-2 Disease
Background: Heat shock proteins (HSPs) are involved in innate and adaptive immune responses, especially inflammatory respo...
Iranian Journal Of Immunology
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Neutrophil Extracellular Traps Formation and Citrullinated Histones 3 Levels in Patients with Kawasaki Disease
Background: Kawasaki disease (KD) is a vasculitis associated with vascular injury and autoimmune response. Inflammatory fa...
Iranian Journal Of Immunology
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Senescent CD153+ T Lymphocytes Increase in the Peripheral Blood of Patients with Thromboangiitis Obliterans
Background: Buerger’s disease, also known as Thromboangiitis Obliterans (TAO), is a progressive, inflammatory vascular dis...
Iranian Journal Of Immunology
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Vol 20, Supplementary Issue, 16th International Congress of Immunology and Allergy
We are delighted to share the Abstract Book of the "16th International Congress of Immunology and Allergy". The ...
Iranian Journal Of Immunology
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IJI, Vol 20, Supplementary Issue, 16th International Congress of Immunology and Allergy
We are delighted to share the Abstract Book of the "16th International Congress of Immunology and Allergy". The ...
Iranian Journal Of Immunology
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Effects of Blocking NLRP3 Inflammasome on Type II Innate Lymphoid Cell Response in Allergic Rhinitis
Background: Type 2 innate lymphoid cells (ILC2s) and NLRP3 inflammasome are related to allergic and inflammatory responses...
Iranian Journal Of Immunology
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Implications of Complement Imbalance in COVID-19: A Molecular Mechanistic Discussion on the Importance of Complement Balance
Two central questions in COVID-19 treatment which should be considered are: “How does the imbalance of the complement syst...
Iranian Journal Of Immunology
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Angiopoietin-like 4 (ANGPTL4) Suppression Ameliorates Lupus Nephritis in MRL/lpr Mice by Inactivating NLRP3 Inflammasome and Inhibiting Inflammatory Response
Background: Lupus nephritis (LN) refers to the injury caused by systemic lupus erythematosus (SLE) involving the kidneys. ...
Iranian Journal Of Immunology
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Impact of Echinococcus granulosus Antigens on Monocyte Development and Dendritic Cell Differentiation
Background: Different subtypes of dendritic cells (DCs) can induce different types of immune responses. Our previous study...
Iranian Journal Of Immunology
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CD39 Expression in Peripheral T Cells is Associated with Clinicopathological Characteristics in Patients with Cervical Cancer
Background: CD39 is an inhibitory checkpoint exerting rate-limiting effects on the ATP-adenosine pathway. It can be target...
Iranian Journal Of Immunology
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SPIB Knockdown Inhibits the Immune Escape of Ovarian Cancer Cells by Reducing PD-L1 (CD274) Expression and Inactivating the JAK/STAT Pathway
Background: Spi-B transcription factor (SPIB) is an E-twenty-six (ETS) transcription factor associated with tumor immunity...
Iranian Journal Of Immunology
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Synthesized Anti-HER2 Trastuzumab-MCC-DM1 Conjugate: An Evaluation of Efficacy and Cytotoxicity
Background: Trastuzumab is a humanized monoclonal antibody that targets site-specifically human epidermal growth factor-2 ...
Iranian Journal Of Immunology
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Increased Serum Levels of IL-1β after Ischemic Stroke are Inversely Associated with Vitamin D
Background: The initial inflammatory reaction starts following occlusion in ischemic stroke (IS). Interleukin-1β (IL-1β) i...
Iranian Journal Of Immunology
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Evaluation of SARS-CoV-2 Specific Antibodies in Recovered Patients by Different ELISA Kits
Background: The coronavirus disease 2019 (COVID-19) was first reported in December 2019 in Wuhan, Hubei Province of China....
Iranian Journal Of Immunology
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The Anti-inflammatory Effect of Ginger Extract on the Animal Model of Multiple Sclerosis
Background: Experimental autoimmune encephalomyelitis (EAE), as an autoimmune disease in the central nervous system (CNS),...
Iranian Journal Of Immunology
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The Upregulation of HLA-G1 and miRNA-34a in Lens Epithelial Cells of Diabetic Retinopathy Patients
Background: Retinopathy of diabetes is a chronic diabetes mellitus complication affecting retinal vessels, and some ocular...
Iranian Journal Of Immunology
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