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A comprehensive analysis of scRNA-Seq and RNA-Seq unveils B cell immune suppression in the AAV-loaded brain
A comprehensive analysis of scRNA-Seq and RNA-Seq unveils B cell immune suppression in the AAV-loaded brain
The use of AAV vectors for in vivo gene therapy has demonstrated the potential to permanently correct genetic diseases by ...
Deciphering autoimmune susceptibility: a meta-analysis of gene variants
Deciphering autoimmune susceptibility: a meta-analysis of gene variants
Autoimmune disorders are intricate conditions where the immune system directs its attack towards the body’s tissues....
Systemic barrier dysfunction in type 2 inflammation diseases: perspective in the skin, airways, and gastrointestinal tract
Systemic barrier dysfunction in type 2 inflammation diseases: perspective in the skin, airways, and gastrointestinal tract
The epithelial barrier in different organs is the first line of defense against environmental insults and allergens, with ...
A novel loss of function mutation in the gene in a patient diagnosed with Hodgkin’s lymphoma
A novel loss of function mutation in the gene in a patient diagnosed with Hodgkin’s lymphoma
Kane LP. T cell Ig and mucin domain proteins and immunity. J Immunol Baltim Md 1950. 2010;184(6):2743–9.CAS  ...
Immunoenhancing of the anti-cancer therapy and anti-oxidative stress by co-administration of granulocyte-colony stimulating factor-mobilized stem cells or cells derived from bone marrow and/or spleen plus vaccination with chemotherapeutic cyclophosphamide
Immunoenhancing of the anti-cancer therapy and anti-oxidative stress by co-administration of granulocyte-colony stimulating factor-mobilized stem cells or cells derived from bone marrow and/or spleen plus vaccination with chemotherapeutic cyclophosphamide
The combination of immunotherapy and chemotherapy, referred to as chemo-immunotherapy, represents a promising regimen for ...
α-Amanitin aggravates hepatic injury by activating oxidative stress and mitophagy via peroxiredoxin 6 inhibition
α-Amanitin aggravates hepatic injury by activating oxidative stress and mitophagy via peroxiredoxin 6 inhibition
Mushroom poisoning is mainly caused by α-amanitin (α-AMA), and there is currently no effective drug to treat ...
Pivotal epitopes for islet antigen-specific CD8 T cell detection improve classification of suspected type 1 diabetes with the HLA-A*0201 allele
Pivotal epitopes for islet antigen-specific CD8 T cell detection improve classification of suspected type 1 diabetes with the HLA-A*0201 allele
A proportion of patients with new-onset diabetes share similar symptoms with type 1 diabetes (T1D) patients but they are n...
Clinical management of autoimmune liver diseases: juncture, opportunities, and challenges ahead
Clinical management of autoimmune liver diseases: juncture, opportunities, and challenges ahead
The three major autoimmune liver diseases are autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary s...
Phenotypic characterization of tumor associated macrophages and circulating monocytes in patients with Urothelial carcinoma of bladder
Phenotypic characterization of tumor associated macrophages and circulating monocytes in patients with Urothelial carcinoma of bladder
Targeting immune checkpoints has shown clinical efficacy in Urothelial carcinoma of bladder (UBC); however, a substantial ...
HBx/WDR5 enhances IGF-1 transcription in hepatocellular carcinoma cells and promotes recruitment, infiltration, and activity of Treg cells
HBx/WDR5 enhances IGF-1 transcription in hepatocellular carcinoma cells and promotes recruitment, infiltration, and activity of Treg cells
HBV X protein (HBx), the smallest open reading frame in the hepatitis B virus (HBV) genome, can promote hepatocellular car...
Role of basophils and type 2 inflammation in bullous pemphigoid pathophysiology: a comparative study of blood and blister fluid
Role of basophils and type 2 inflammation in bullous pemphigoid pathophysiology: a comparative study of blood and blister fluid
Bullous pemphigoid (BP) is an autoimmune disease characterized by blister formation and inflammatory cell infiltration. In...
Comparison of artificial intelligence applications and commercial system performances using selected ANA IIF images
Comparison of artificial intelligence applications and commercial system performances using selected ANA IIF images
Accurate and accessible classification of anti-nuclear antibodies (ANA) through indirect immunofluorescence (IIF) imaging ...
Baicalin restores innate lymphoid immune imbalance during exacerbation of COPD
Baicalin restores innate lymphoid immune imbalance during exacerbation of COPD
Chronic obstructive pulmonary disease (COPD) is characterized by immune dysregulation, including altered innate lymphoid c...
Immunomodulatory effects of alexidine dihydrochloride on mammalian macrophages through the modulation of the JNK pathway
Immunomodulatory effects of alexidine dihydrochloride on mammalian macrophages through the modulation of the JNK pathway
A plethora of the cancer drugs with high therapeutic potential cannot pass the clinical trials because of their immunotoxi...
The urease E subunit vaccine stimulate the immune response versus in animal model
The urease E subunit vaccine stimulate the immune response versus in animal model
There is a strong association between Helicobacter pylori (H. pylori) and the occurrence of gastritis and gastric mucosal ...
The effect of anti-CD20 on inflammation and histopathological alternations in rat photothrombotic ischemic stroke model
The effect of anti-CD20 on inflammation and histopathological alternations in rat photothrombotic ischemic stroke model
Ischemic stroke (IS) has remained the main cause of mortality and neurological disabilities worldwide. Anti-CD20 treatment...
Role of artificial intelligence in advancing immunology
Role of artificial intelligence in advancing immunology
Artificial intelligence (AI) has revolutionized various biomedical fields, particularly immunology, by enhancing vaccine d...
Long non-coding RNA ENSMUST00000197208 promotes a shift in the Th17/Treg ratio via the P2X7R-NLRP3 inflammasome axis in collagen-induced arthritis
Long non-coding RNA ENSMUST00000197208 promotes a shift in the Th17/Treg ratio via the P2X7R-NLRP3 inflammasome axis in collagen-induced arthritis
Recently, long non‑coding RNAs (lncRNAs) have been implicated in several human diseases, including arthritis. Howeve...
A ubiquitin–proteasome system-related signature to predict prognosis, immune infiltration, and therapy efficacy for breast cancer
A ubiquitin–proteasome system-related signature to predict prognosis, immune infiltration, and therapy efficacy for breast cancer
The ubiquitin–proteasome system (UPS) is an essential regulatory system for maintaining homeostasis, and its dysfunc...
Immune cells and hypertension
Immune cells and hypertension
Hypertension is one of the leading causes of death due to target organ injury from cardiovascular disease. Although there ...
Correction: Major histocompatibility complex class I molecule expression by pancreatic cancer cells is regulated by activation and inhibition of the epidermal growth factor receptor
Correction: Major histocompatibility complex class I molecule expression by pancreatic cancer cells is regulated by activation and inhibition of the epidermal growth factor receptor
Cite this articleKnoche, S.M., Larson, A.C., Brumfield, G.L. et al. Correction: Major histocompatibility complex class I m...
Fructus lycii oligosaccharide alleviates acute liver injury via PI3K/Akt/mTOR pathway
Fructus lycii oligosaccharide alleviates acute liver injury via PI3K/Akt/mTOR pathway
Regulating the immune-environment is essential for treating acute liver injury (ALI). However, the deficiency of an effect...
Comparative analyses of various IgE-mediated and non-IgE-mediated inducers of mast cell degranulation for in vitro study
Comparative analyses of various IgE-mediated and non-IgE-mediated inducers of mast cell degranulation for in vitro study
In vitro investigations of mast cell (MC) degranulation are essential for studying many diseases, particularly allergy and...
Impact of microparticles released during murine systemic inflammation on macrophage activity and reactive nitrogen species regulation
Impact of microparticles released during murine systemic inflammation on macrophage activity and reactive nitrogen species regulation
Microparticles (MPs) packaged with numerous bioactive molecules are essential vehicles in cellular communication in variou...
Insights into the immunological description of cryoglobulins with regard to detection and characterization in Slovenian rheumatological patients
Insights into the immunological description of cryoglobulins with regard to detection and characterization in Slovenian rheumatological patients
The detection of cryoglobulins (CG) used to diagnose cryoglobulinemic vasculitis requires strict adherence to protocol, wi...
Semaphorin 3 a restores the ability of type 1 regulatory T cells to suppress food allergy
Semaphorin 3 a restores the ability of type 1 regulatory T cells to suppress food allergy
Food allergy (FA) is a common immune disorder that involves dysfunctional immune regulation. More remedies for restoring i...
Prevalence and sociodemographic correlates of antinuclear antibody testing by indirect immunofluorescence or solid-phase assays in a Spanish population: the Camargo Cohort
Prevalence and sociodemographic correlates of antinuclear antibody testing by indirect immunofluorescence or solid-phase assays in a Spanish population: the Camargo Cohort
Autoantibodies are the hallmark of autoimmunity, and specifically, antinuclear antibodies (ANA) are one of the most releva...
Association of IL-23R and IL-10 variations with Behçet disease: a genetic analysis study
Association of IL-23R and IL-10 variations with Behçet disease: a genetic analysis study
Behçet disease (BD) is an autoimmune and autoinflammatory disease mainly affecting the Silk Road countries. The inter...
Role of LINC00240 on T-helper 9 differentiation in allergic rhinitis through influencing DNMT1-dependent methylation of PU.1
Role of LINC00240 on T-helper 9 differentiation in allergic rhinitis through influencing DNMT1-dependent methylation of PU.1
Allergic rhinitis (AR) is a common allergic disease with increasing prevalence globally. However, the molecular mechanism ...
Increased synthesis and intestinal expression of IL-39 in patients with inflammatory bowel disease
Increased synthesis and intestinal expression of IL-39 in patients with inflammatory bowel disease
IL-39 (Interleukin-39) is a heterodimeric cytokine composed of IL-23p19 and EBI3 (Epstein-Barr virus-induced gene 3) subun...
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