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Neuroimmune interactions between itch neurons and skin microbes
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The spatial and single-cell landscape of skin: Charting the multiscale regulation of skin immune function
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Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): Insights into pathogenesis and biomarkers of prognosis
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The immunological processes behind aquaporin 4-antibody seropositive neuromyelitis optica spectrum disorders
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The role of the adaptive immune system in the initiation and persistence of multiple sclerosis
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From immunobiology to intervention: Pathophysiology of autoimmune encephalitis
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The pathogenesis of neurological immune-related adverse events following immune checkpoint inhibitor therapy
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Unraveling the pathophysiology of narcolepsy type 1 through hypothesis-driven and hypothesis-generating approaches
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Interferon regulatory factor 3 beyond innate immunity: Regulation in obesity and metabolic disorders
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Immune dysregulation of diabetes in tuberculosis
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Endogenous glucocorticoids and human immunity: Time to revisit old dogmas
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The stress and the alarmin-like cytokine interleukin-37 mediated extracellular and intracellular signal pathways
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Cellular stress and macrophage activation
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Endoplasmic reticulum stress: A key player in immune cell regulation and autoimmune disorders
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Acetylation and deacetylation dynamics in stress response to cancer and infections
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An evolutionary perspective of the roles of galectins in pathogen recognition and immunity
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Local and Cell-intrinsic complement: The new player in cancer progression
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Oncolytic virus-mediated immunomodulation in glioblastoma: Insights from clinical trials and challenges
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A framework for the rational design of oncolytic viruses: A holistic perspective considering the tumour microenvironment
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To die or not to die: Gasdermins in intestinal health and disease
To die or not to die: Gasdermins in intestinal health and disease
The first member of the gasdermin family was identified in the upper gastrointestinal tract in 2000 [1]. Up until now, the...
Gut-liver axis: Pathophysiological concepts and medical perspective in chronic liver diseases
Gut-liver axis: Pathophysiological concepts and medical perspective in chronic liver diseases
AhRAryl hydrocarbon receptorASHalcoholic steatohepatitisACLFacute-on-chronic-liver-failureASBTApical Sodium-dependent BA T...
Type I and type III interferons: From basic biology and genetics to clinical development for COVID-19 and beyond
Type I and type III interferons: From basic biology and genetics to clinical development for COVID-19 and beyond
Type I interferons (IFNs) constitute a major antiviral defense system of the body. They were discovered over 60 years ago ...
Toolkit for mapping the clonal landscape of tumor-infiltrating B cells
Toolkit for mapping the clonal landscape of tumor-infiltrating B cells
Resolving intratumoral B cells and IG-producing plasma cell content is critical for our understanding of tumor-immunity in...
Antigen cross-presentation by dendritic cells: A critical axis in cancer immunotherapy
Antigen cross-presentation by dendritic cells: A critical axis in cancer immunotherapy
Volume 71, February 2024, 101848Author links open overlay panel, AbstractDendritic cells (DCs) are professional antigen-pr...
Regulated cell death in neutrophils: From apoptosis to NETosis and pyroptosis
Regulated cell death in neutrophils: From apoptosis to NETosis and pyroptosis
Volume 70, November 2023, 101849Author links open overlay panel, , , AbstractNeutrophils are among the most abundant immun...
Regulatory T cells in allergic inflammation
Regulatory T cells in allergic inflammation
APCsAntigen-presenting cellsAT2Type II alveolar cellsαVβ8alpha-V:beta-8 integrinα4β7Alpha 4 beta 7 integrinCCR6C-C Motif C...
Chemical modulation of gasdermin D activity: Therapeutic implications and consequences
Chemical modulation of gasdermin D activity: Therapeutic implications and consequences
Volume 70, November 2023, 101845Author links open overlay panel, Highlights•The gasdermin family of proteins are terminal ...
The epithelial barrier: The gateway to allergic, autoimmune, and metabolic diseases and chronic neuropsychiatric conditions
The epithelial barrier: The gateway to allergic, autoimmune, and metabolic diseases and chronic neuropsychiatric conditions
KeywordsAllergyAutoimmune diseasesBarrier dysfunctionEpithelitisEpithelial barrier theoryLungsMetabolic diseasesMicrobiota...
The noncanonical inflammasome-induced pyroptosis and septic shock
The noncanonical inflammasome-induced pyroptosis and septic shock
AbbreviationAAK1AP2 Associated Kinase 1AOAHAcyloxyacyl hydrolaseCARDCaspase recruitment and activation domaincGASCyclic GM...