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Pathogenic role of CD169+ macrophages in neuronal loss and motor decline in NMO mice
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Sex-specific proteomic analysis of epileptic brain tissues from Pten knockout mice and human refractory epilepsy
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Intermittent transcutaneous auricular vagus nerve stimulation reverses acute stress-induced memory deficits via O-GlcNAc modulation
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Aromatase inhibition modulates intrinsic properties and excitability of hippocampal CA1 pyramidal cells in the APP/PS1 mouse model of Alzheimer's disease
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ZFHX3 silencing alleviates ischemic stroke by suppressing pericyte contraction and calcium influx through inhibiting WNK3 expression
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The chronic aftermath of recurrent intimate partner violence-related brain injuries: Insights from rat models of traumatic brain injury and non-fatal strangulation
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SerpinA3N inhibits mitochondrial complex I activity to prevent neuron ferroptosis following cerebral ischemic stroke
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HDAC6 inhibition enhances peroxiredoxin 1 acetylation to mitigate oxidative stress and seizure activity in focal cortical dysplasia
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Effect of activated autophagy on an animal model of vestibular migraine-like attacks
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Comparison of blood-brain barrier permeability changes in gyrencephalic (ferret & non-human primate) and lissencephalic (rat) models following blast overpressure exposures
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Microglia interact with dendritic spines and regulate spine numbers after brain injury following resuscitation from a cardiac arrest
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Elucidating the mechanistic role of Rip3 in post-thalamic hemorrhage neurological deficits
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Letter to the editor: “Exploring the potential of routine serological markers in predicting neurological outcomes in spinal cord injury” by Jan Matthias et al
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Response to the Editor - Exploring the Potential of routine serological markers in predicting neurological outcomes in spinal cord injury
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A guide to developing harmonized research workflows in a team science context
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KIF23 inhibition protects against perioperative neurocognitive disorders by hindering ROS/caspase-3/GSDME-mediated pyroptosis
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Ischemic stroke altered the expression profiles of super enhancer RNAs in mouse brain in a sexually dimorphic manner
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Protein kinase C gamma regulates Purkinje cell dendritic spine development in a mouse model of spinocerebellar ataxia
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Cell-generated mechanical forces play a role in epileptogenesis after injury
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Zonisamide modulates cholinergic markers and alleviates levodopa-induced dyskinesia in a rat model of Parkinson's disease
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Multi-session transcutaneous spinal cord stimulation prevents chloride homeostasis imbalance and the development of hyperreflexia after spinal cord injury in rat
Multi-session transcutaneous spinal cord stimulation prevents chloride homeostasis imbalance and the development of hyperreflexia after spinal cord injury in rat
Spasticity is a complex and multidimensional disorder that impacts nearly 75% of individuals with spinal cord injury (SCI)...
Social isolation initiated post-weaning augments ischemic brain injury by promoting pro-inflammatory responses
Social isolation initiated post-weaning augments ischemic brain injury by promoting pro-inflammatory responses
Social isolation, experienced during early development or in adulthood, has detrimental consequences for physical and ment...
PI3Kδ inhibition alleviates the brain injury during cerebral ischemia reperfusion via suppressing pericyte contraction in a TNF-α dependent manner
PI3Kδ inhibition alleviates the brain injury during cerebral ischemia reperfusion via suppressing pericyte contraction in a TNF-α dependent manner
As the common type of stroke, ischemic stroke is the leading cause of the permanent disability worldwide, and brings about...
To evaluate the effect of endothelin receptor agonist IRL-1620 alone and in combination with donepezil in modulating neurodegeneration elicited by amyloid-β in rats
To evaluate the effect of endothelin receptor agonist IRL-1620 alone and in combination with donepezil in modulating neurodegeneration elicited by amyloid-β in rats
Alzheimer's disease (AD) which is the most prevailing class of dementia, accounting for nearly two-thirds of dementia inst...
Ndfip1 protected dopaminergic neurons via regulating mitochondrial function and ferroptosis in Parkinson's disease
Ndfip1 protected dopaminergic neurons via regulating mitochondrial function and ferroptosis in Parkinson's disease
PD is a common neurodegenerative disease with both motor and non-motor symptoms. The main pathological changes of PD are t...
Investigating neuropathological changes and underlying neurobiological mechanisms in the early stages of primary blast-induced traumatic brain injury: Insights from a rat model
Investigating neuropathological changes and underlying neurobiological mechanisms in the early stages of primary blast-induced traumatic brain injury: Insights from a rat model
The use of explosive weapons and chemical agents has resulted in an increase in blast-induced traumatic brain injury (bTBI...
Effects of dim light at night in C57BL/6 J mice on recovery after spinal cord injury
Effects of dim light at night in C57BL/6 J mice on recovery after spinal cord injury
The Earth has rotated on its axis for billions of years, creating daily environmental rhythms of light and dark. These pre...
Nfe2l3 promotes neuroprotection and long-distance axon regeneration after injury in vivo
Nfe2l3 promotes neuroprotection and long-distance axon regeneration after injury in vivo
Nfe2l3 (also known as Nrf3) belongs to the Cap'n'collar (Cnc) family of proteins, along with Nfe2l1 and Nfe2l2, which regu...
Engineered PDGFA-ligand-modified exosomes delivery T3 for demyelinating disease targeted therapy
Engineered PDGFA-ligand-modified exosomes delivery T3 for demyelinating disease targeted therapy
Demyelination is a proper syndrome in plenty of central nervous system (CNS) diseases, which is the main obstacle to recov...
microRNA-9a-5p disrupts the ELAVL1/VEGF axis to alleviate traumatic brain injury
microRNA-9a-5p disrupts the ELAVL1/VEGF axis to alleviate traumatic brain injury
Traumatic brain injury (TBI) is damage to the brain caused by an external force (Stocchetti et al., 2017). The major cause...
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