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Editorial: Enhancing companion animal welfare through advanced behavioral management strategies
Our research topic brings together four studies that explore different aspects of this challenge by adopting a comprehensi...
I’ve got a friend somewhere: control of social behavior across striatal subregions
Most animals and humans are inherently social, enabling group dynamics to promote survival. Despite their importance, how ...
Aggressiveness that makes one grow: a destructive or vital force in adolescence? Reflections and working hypotheses
Adolescence is a critical developmental stage marked by profound physical, emotional, and social transformations. During t...
Glutamate transmission in the prelimbic cortex and nucleus accumbens shell is involved in ethanol reinforcement and drinking in rats
IntroductionResearch has implicated mesocorticolimbic glutamate transmission in alcohol use. The current study focused on ...
Female rats adopt a safety-first strategy in a high-conflict platform mediated avoidance task
Maladaptive avoidance is a central feature of many mental disorders, particularly stress- and anxiety-related disorders. T...
Sex, social rank, and nicotine co-administration shape cocaine- and cocaethylene-induced reinstatement in monkeys
IntroductionCocaine use disorder (CUD) is highly comorbid with alcohol and nicotine use, yet preclinical research rarely m...
Editorial: Sex as a biological variable in the neurocircuitry of motivated behavior
primarily include midbrain dopaminergic nuclei and their projections to the ventral striatum, but also includes upstream h...
Sex differences in neurobehavior and the adult hippocampal neurogenic niche: influence of traumatic brain injury and CLIP antagonism
Sex differences in neurobehavior and the adult hippocampal neurogenic niche: influence of traumatic brain injury and CLIP antagonism
IntroductionTraumatic brain injury (TBI) is a major cause of death and disability worldwide. Alterations to adult hippocam...
An exploratory study of behavioral, cognitive, physiological, and microbiota profiles in senior dogs
IntroductionAging in dogs is a multifactorial process involving behavioral, cognitive, immunological, and microbiota-relat...
Craving as a transdiagnostic marker of addiction? A perspective for behavioral addictions
The addiction term is sometimes overused, both in the media and popular discourse, to describe excessive engagement in eve...
Adolescent social instability stress alters social processes in male prairie voles
Adolescence is a sensitive period for the maturation of neural circuits governing goal-directed social behaviors and stres...
From the lab to the real world: emotions serving morality in dyadic negotiation
IntroductionConfronting moral choices in contexts of limited resources requires individuals to integrate reasoning, emotio...
Goal-directed actions and habits in head-fixed mice
BackgroundBehavioral control is fundamentally governed by a dynamic balance between flexible, goal-directed actions and ef...
Single neuron responses in NCL, MVL, and Wulst during the observation of videos of conspecifics support population feature coding
Social visual processing in vertebrates employs sophisticated neural mechanisms ranging from categorical face cells to dis...
From observation to optimization: behavioral metrics that matter in KPI based home cage monitoring
From observation to optimization: behavioral metrics that matter in KPI based home cage monitoring
Most in vivo scientists would agree that digital biomarkers collected via home-cage monitoring generate valuable data. How...
Prefrontal cortical deficits are a putative susceptibility factor for PTSD
IntroductionOnly a subset of people who experience a traumatic event develop Post-Traumatic Stress Disorder (PTSD) suggest...
Vicarious learned helplessness: a translationally relevant novel model of stress contagion elucidating sex-dependent prefrontal cortex pathology
IntroductionVicarious trauma, the psychological distress from witnessing others’ suffering, is an increasingly recognized ...
Case Report: Wernicke’s encephalopathy induced by prolonged fasting due to apparent psychogenic dysphagia
BackgroundWernicke’s encephalopathy (WE) is an acute neurologic emergency resulting from thiamine deficiency that can caus...
Sex differences in taste neophobia and conditioned aversion across fluid administration methods
Rodent studies of the taste system commonly employ two methods of taste administration (MOA): active licking from spouts o...
Sex and gender as contributors to brain pathophysiology, clinical course, and therapeutic response in multiple sclerosis
Multiple sclerosis (MS) is a chronic autoimmune demyelinating disorder that affects the brain and spinal cord. MS is chara...
Post-weaning social isolation alters sociability in a sex-specific manner
Post-weaning social isolation alters sociability in a sex-specific manner
Adolescence is a critical period for brain development in humans and stress exposure during this time can have lasting eff...
Impairments of social interaction in a valproic acid model in mice
Impairments of social interaction in a valproic acid model in mice
BackgroundA rodent autism spectrum disorder (ASD) model based on prenatal exposure to valproic acid (VPA) is widely recogn...
Spatial memory and learning: investigating the role of dynamic visual acuity
Spatial memory and learning: investigating the role of dynamic visual acuity
IntroductionThe vestibular system’s contribution to spatial learning and memory abilities may be clarified using the virtu...
Continuous locomotor activity monitoring to assess animal welfare following intracranial surgery in mice
Continuous locomotor activity monitoring to assess animal welfare following intracranial surgery in mice
Locomotor activity can serve as a readout to identify discomfort and pain. Therefore, monitoring locomotor activity follow...
Chronic exposure to MK-801 leads to olfactory deficits and reduced neurogenesis in the olfactory bulbs of adult male mice
Chronic exposure to MK-801 leads to olfactory deficits and reduced neurogenesis in the olfactory bulbs of adult male mice
BackgroundMK-801 is a drug widely used in preclinical studies to model schizophrenia in animals. Its distinctive feature i...
VGLUT2 may improve cognitive function in depressed rats by protecting prefrontal cortex neurons
VGLUT2 may improve cognitive function in depressed rats by protecting prefrontal cortex neurons
ObjectiveDepression may be accompanied by cognitive impairment, but its pathogenesis remains unclear. This study aims to i...
Behavioral, neurotransmitter and transcriptomic analyses in male and female Fmr1 KO mice
Behavioral, neurotransmitter and transcriptomic analyses in male and female Fmr1 KO mice
IntroductionFragile X syndrome is an inherited X-linked disorder associated with intellectual disabilities that begin in c...
Unveiling the influence of persuasion strategies on cognitive engagement: an ERPs study on attentional search
Unveiling the influence of persuasion strategies on cognitive engagement: an ERPs study on attentional search
The objective of this study was to explore the impact of different persuasive strategies, as delineated in the Elaboration...
Parkinson’s LRRK2-G2019S risk gene mutation drives sex-specific behavioral and cellular adaptations to chronic variable stress
Parkinson’s LRRK2-G2019S risk gene mutation drives sex-specific behavioral and cellular adaptations to chronic variable stress
Anxiety is a psychiatric non-motor symptom of Parkinson’s that can appear in the prodromal period, prior to significant lo...
Adult auditory brain responses to nestling begging calls in seasonal songbirds: an fMRI study in non-parenting male and female starlings (Sturnus vulgaris)
Adult auditory brain responses to nestling begging calls in seasonal songbirds: an fMRI study in non-parenting male and female starlings (Sturnus vulgaris)
The present study aims to investigate whether begging calls elicit specific auditory responses in non-parenting birds, whe...
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