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Multiscale characterization of cortical signatures in positive and negative schizotypy: a worldwide ENIGMA study
Multiscale characterization of cortical signatures in positive and negative schizotypy: a worldwide ENIGMA study
Positive and negative schizotypy reflect distinct patterns of subclinical traits in the general population associated with...
Genetic overlap and shared risk loci between autism spectrum disorder and cardiometabolic traits
Genetic overlap and shared risk loci between autism spectrum disorder and cardiometabolic traits
Autism spectrum disorder (ASD) is a neurodevelopmental condition affecting 2% of the global population. Beyond core sympto...
Single-cell transcriptomics of human brain disorders
Single-cell transcriptomics of human brain disorders
Brain disease is ultimately a disease of its constituent cells, and single-cell genomics has recently begun to illuminate ...
Re-evaluating the effectiveness of ultrabrief pulse ECT: the potential role of (In)appropriate seizure threshold titration
Re-evaluating the effectiveness of ultrabrief pulse ECT: the potential role of (In)appropriate seizure threshold titration
Jelovac A, McLoughlin DM. Ultrabrief pulse electroconvulsive therapy for depression: a systematic review and meta-analysis...
Shared and disorder-specific prenatal and perinatal risk factors for neurodevelopmental disorders: a nationwide cohort study
Shared and disorder-specific prenatal and perinatal risk factors for neurodevelopmental disorders: a nationwide cohort study
Neurodevelopmental disorders (NDDs) are common, frequently co-occur, and impose a substantial burden, yet the extent to wh...
Multimodal microglial and kynurenine pathway alterations across the affective-psychosis spectrum: a systematic review of patterns, heterogeneity, and dimensional implications
Multimodal microglial and kynurenine pathway alterations across the affective-psychosis spectrum: a systematic review of patterns, heterogeneity, and dimensional implications
Immune dysregulation is implicated in patient subgroups in major depressive disorder (MDD), bipolar disorder (BD) and schi...
Cell-type-specific genetic architecture reveals neuronal and immune contributions to neuropsychiatric disorders
Cell-type-specific genetic architecture reveals neuronal and immune contributions to neuropsychiatric disorders
Neuropsychiatric disorders exhibit complex polygenic architectures, yet the cell-type-specific mechanisms underlying most ...
IL-15 receptor alpha deficiency triggers depressive-like behaviors via enhanced microglial synapse pruning
IL-15 receptor alpha deficiency triggers depressive-like behaviors via enhanced microglial synapse pruning
Major Depressive Disorder (MDD) is a serious mental illness, and neuroinflammation is increasingly recognized as a contrib...
Correction: Short- and long-term modulation of rat prefrontal cortical activity following single doses of psilocybin
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
The role of low subcortical iron, white matter myelin, and oligodendrocytes in schizophrenia: a quantitative susceptibility mapping and diffusion tensor imaging study
The role of low subcortical iron, white matter myelin, and oligodendrocytes in schizophrenia: a quantitative susceptibility mapping and diffusion tensor imaging study
Iron—the most abundant magnetic brain substance—is essential for many biological processes, including dopamine...
Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth
Impulsivity and neuroticism share distinct functional connectivity signatures with alcohol-use risk in youth
Increases in impulsivity and negative affect (e.g., neuroticism) are common during adolescence and are both associated wit...
Altered striosome-matrix distribution and activity of striatal cholinergic interneurons in a model of autism-linked repetitive behaviors
Altered striosome-matrix distribution and activity of striatal cholinergic interneurons in a model of autism-linked repetitive behaviors
Repetitive behaviors are cardinal features of many brain disorders, including autism spectrum disorder (ASD). We previousl...
Astrocytic Mettl14 depletion enhances cognitive function by attenuating astrogliosis via the DUSP1/MAPK pathway in APP/PS1 mice: targeting neuroinflammation in Alzheimer’s disease
Astrocytic Mettl14 depletion enhances cognitive function by attenuating astrogliosis via the DUSP1/MAPK pathway in APP/PS1 mice: targeting neuroinflammation in Alzheimer’s disease
Alzheimer’s disease (AD), a leading cause of dementia, represents a critical unmet global medical need. While the pr...
GABAA receptor availability in clinical high-risk and first-episode psychosis: a [11C]Ro15-4513 positron emission tomography study
GABAA receptor availability in clinical high-risk and first-episode psychosis: a [11C]Ro15-4513 positron emission tomography study
Disrupted gamma-aminobutyric acid (GABA) neurotransmission may contribute to the pathophysiology of schizophrenia. Reducti...
Hyperactivity of subicular parvalbumin interneurons drives early amyloid pathology and cognitive deficits in Alzheimer’s disease
Hyperactivity of subicular parvalbumin interneurons drives early amyloid pathology and cognitive deficits in Alzheimer’s disease
Atrophy of the subiculum is the earliest hippocampal anatomical marker of Alzheimer’s disease (AD) and is closely as...
Consortium profile: the methylation, imaging and NeuroDevelopment (MIND) consortium
Consortium profile: the methylation, imaging and NeuroDevelopment (MIND) consortium
Epigenetic processes, such as DNA methylation, show potential as biological markers and mechanisms underlying gene-environ...
Rightward brain structural asymmetry in young children with autism
Rightward brain structural asymmetry in young children with autism
To understand the neural mechanism of autism spectrum disorder (ASD) and developmental delay/intellectual disability (DD/I...
Cannabidiol abrogates cue-induced anxiety associated with normalization of mitochondria-specific transcripts and linoleic acid in the nucleus accumbens shell
Cannabidiol abrogates cue-induced anxiety associated with normalization of mitochondria-specific transcripts and linoleic acid in the nucleus accumbens shell
Anxiety disorders are one of the top contributors to psychiatric burden worldwide. Recent years have seen a dramatic rise ...
Acid sphingomyelinase activity suggests a new antipsychotic pharmaco-treatment strategy for schizophrenia
Acid sphingomyelinase activity suggests a new antipsychotic pharmaco-treatment strategy for schizophrenia
Schizophrenia is a chronic and severe mental disorder. It is currently treated with antipsychotic drugs (APD). However, AP...
How does oxytocin modulate human behavior?
How does oxytocin modulate human behavior?
While the highly evolutionarily conserved hypothalamic neuropeptide, oxytocin (OT) can influence cognitive, emotional and ...
Effects of oxytocin administration on non-social executive functions in humans: a preregistered systematic review and meta-analysis
Effects of oxytocin administration on non-social executive functions in humans: a preregistered systematic review and meta-analysis
Oxytocin has received considerable research attention for its role in affiliative behaviors, particularly regarding its pr...
Treatment-resistant depression: role of genetic factors in the perspective of clinical stratification and treatment personalisation
Treatment-resistant depression: role of genetic factors in the perspective of clinical stratification and treatment personalisation
Treatment-resistant depression (TRD) is associated with chronic depression, suicidal behaviours, and reduced quality of li...
Novel synaptic markers predict early tau pathology and cognitive deficit in an asymptomatic population at risk of Alzheimer’s disease
Novel synaptic markers predict early tau pathology and cognitive deficit in an asymptomatic population at risk of Alzheimer’s disease
Cognitive dysfunction in Alzheimer’s disease (AD) correlates closely with pathology in the neuronal microtubule-asso...
Frequency-specific and state-dependent neural responses to brain stimulation
Frequency-specific and state-dependent neural responses to brain stimulation
Non-invasive brain stimulation is promising for treating many neuropsychiatric and neurological conditions. It could be op...
Correction: Electroconvulsive therapy-induced volumetric brain changes converge on a common causal circuit in depression
Feinstein Institutes for Medical Research, Institute of Behavioral Science, Manhasset, NY, USAMiklos Argyelan, Brian Angul...
Oxytocin activity in the paraventricular and supramammillary nuclei of the hypothalamus is essential for social recognition memory in rats
Oxytocin activity in the paraventricular and supramammillary nuclei of the hypothalamus is essential for social recognition memory in rats
Oxytocin plays an important role in modulating social recognition memory. However, the direct implication of oxytocin neur...
Maternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescence
Maternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescence
Maternal educational attainment (MEA) shapes offspring health through multiple potential pathways. Differential DNA methyl...
“Puberty age gap”: new method of assessing pubertal timing and its association with mental health problems
“Puberty age gap”: new method of assessing pubertal timing and its association with mental health problems
Puberty is linked to mental health problems during adolescence, and in particular, the timing of puberty is thought to be ...
Choroid plexus and perivascular space enlargement in neuropsychiatric systemic lupus erythematosus
Choroid plexus and perivascular space enlargement in neuropsychiatric systemic lupus erythematosus
Choroid plexus (CP) enlargement is proposed as a marker of neuroinflammation in immune-mediated conditions. CP involvement...
The neural signature of psychomotor disturbance in depression
The neural signature of psychomotor disturbance in depression
Up to 70% of patients with major depressive disorder present with psychomotor disturbance (PmD), but at the present time u...
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