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FTO (fat-mass and obesity-associated protein) deficiency aggravates age-dependent depression-like behaviors and cognitive impairment
FTO (fat-mass and obesity-associated protein) deficiency aggravates age-dependent depression-like behaviors and cognitive impairment
The demethylase fat mass and obesity-related associated protein (FTO) is strongly associated with depression. Aging is a r...
Gper1 inhibition exacerbates traumatic brain injury-induced neurological impairments in mice
Gper1 inhibition exacerbates traumatic brain injury-induced neurological impairments in mice
G protein-coupled estrogen receptor 1 (Gper1) is widely expressed in the brain, while its function in traumatic brain inju...
Behavioral phenotyping identifies autism-like repetitive stereotypies in a Tsc2 haploinsufficient rat model
Behavioral phenotyping identifies autism-like repetitive stereotypies in a Tsc2 haploinsufficient rat model
Besides deficits in social communication and interaction, repetitive behavior patterns are core manifestations of autism s...
Impaired theta and low-gamma directed information flow in the hippocampal-prefrontal circuit underlies working memory deficits in APP/PS1 mice
Impaired theta and low-gamma directed information flow in the hippocampal-prefrontal circuit underlies working memory deficits in APP/PS1 mice
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline. Working mem...
Knockout of Bmal1 in dopaminergic neurons induces ADHD-like symptoms via hyperactive dopamine signaling in male mice
Knockout of Bmal1 in dopaminergic neurons induces ADHD-like symptoms via hyperactive dopamine signaling in male mice
The central circadian clock coordinates daily oscillations in physiology, metabolism and behavior. Disruptions to core cir...
Inhibition of astroglial hemichannels ameliorates infrasonic noise induced short-term learning and memory impairment
Inhibition of astroglial hemichannels ameliorates infrasonic noise induced short-term learning and memory impairment
As a kind of environmental noise, infrasonic noise has negative effects on various human organs. To date, research has sho...
Functional connectivity patterns in parosmia
Functional connectivity patterns in parosmia
Parosmia is a qualitative olfactory dysfunction presenting as “distorted odor perception” in presence of an od...
Behavioral characterization of early nicotine withdrawal in the mouse: a potential model of acute dependence
Behavioral characterization of early nicotine withdrawal in the mouse: a potential model of acute dependence
Clinical and preclinical research have demonstrated that short-term exposure to nicotine during the initial experimentatio...
Structural connectome alterations between individuals with autism and neurotypical controls using feature representation learning
Structural connectome alterations between individuals with autism and neurotypical controls using feature representation learning
Autism spectrum disorder is one of the most common neurodevelopmental conditions associated with sensory and social commun...
The role of melatonin deficiency induced by pinealectomy on motor activity and anxiety responses in young adult, middle-aged and old rats
The role of melatonin deficiency induced by pinealectomy on motor activity and anxiety responses in young adult, middle-aged and old rats
Aging affects anxiety levels in rats while the pineal gland, via its hormone melatonin, could modulate their inherited lif...
Reactivity of the ventromedial prefrontal cortex, but not the amygdala, to negative emotion faces predicts greed personality trait
Reactivity of the ventromedial prefrontal cortex, but not the amygdala, to negative emotion faces predicts greed personality trait
This study explored whether amygdala reactivity predicted the greed personality trait (GPT) using both task-based and rest...
Specific brain imaging alterations underlying autistic traits in children with attention-deficit/hyperactivity disorder
Specific brain imaging alterations underlying autistic traits in children with attention-deficit/hyperactivity disorder
Autistic traits (ATs) are frequently reported in children with Attention-Deficit/Hyperactivity Disorder (ADHD). This study...
Mapping the neuroanatomical abnormalities in a phenotype of male compulsive rats
Mapping the neuroanatomical abnormalities in a phenotype of male compulsive rats
Compulsivity is considered a transdiagnostic dimension in obsessive–compulsive and related disorders, characterized ...
Multivariate multiscale entropy (mMSE) as a tool for understanding the resting-state EEG signal dynamics: the spatial distribution and sex/gender-related differences
Multivariate multiscale entropy (mMSE) as a tool for understanding the resting-state EEG signal dynamics: the spatial distribution and sex/gender-related differences
The study aimed to determine how the resting-state EEG (rsEEG) complexity changes both over time and space (channels). The...
Causal associations between sleep traits and brain structure: a bidirectional Mendelian randomization study
Causal associations between sleep traits and brain structure: a bidirectional Mendelian randomization study
Emerging evidence suggests bidirectional causal relationships between sleep disturbance and psychiatric disorders, but the...
Well-being is associated with cortical thickness network topology of human brain
Well-being is associated with cortical thickness network topology of human brain
Living a happy and meaningful life is an eternal topic in positive psychology, which is crucial for individuals’ phy...
Transcranial magnetic stimulation and transcranial direct current stimulation affect explicit but not implicit emotion regulation: a meta-analysis
Transcranial magnetic stimulation and transcranial direct current stimulation affect explicit but not implicit emotion regulation: a meta-analysis
Emotion regulation (ER) refers to the process through which people influence the occurrence, experience, and expression of...
Ocular and neural genes jointly regulate the visuospatial working memory in ADHD children
Ocular and neural genes jointly regulate the visuospatial working memory in ADHD children
Working memory (WM) deficits have frequently been linked to attention deficit hyperactivity disorder (ADHD). Despite previ...
Enhancement of dynamic visual acuity using transcranial alternating current stimulation with gamma burst entrained on alpha wave troughs
Enhancement of dynamic visual acuity using transcranial alternating current stimulation with gamma burst entrained on alpha wave troughs
Cross-frequency phase-amplitude coupling (PAC) of cortical oscillations is observed within and across cortical regions dur...
The mediating role of default mode network during meaning-making aroused by mental simulation between stressful events and stress-related growth: a task fMRI study
The mediating role of default mode network during meaning-making aroused by mental simulation between stressful events and stress-related growth: a task fMRI study
Stressful events and meaning-making toward them play an important role in adolescents’ life and growth. However, ign...
Optogenetic stimulation of basal forebrain cholinergic neurons prevents neuroinflammation and neuropsychiatric manifestations in pristane induced lupus mice
Optogenetic stimulation of basal forebrain cholinergic neurons prevents neuroinflammation and neuropsychiatric manifestations in pristane induced lupus mice
Neuroinflammation has been identified as one of the primary pathogenic factors of neuropsychiatric systemic lupus erythema...
Cumulative genetic score of KIAA0319 affects reading ability in Chinese children: moderation by parental education and mediation by rapid automatized naming
Cumulative genetic score of KIAA0319 affects reading ability in Chinese children: moderation by parental education and mediation by rapid automatized naming
KIAA0319, a well-studied candidate gene, has been shown to be associated with reading ability and developmental dyslexia. ...
Oleoylethanolamide attenuates cocaine-primed reinstatement and alters dopaminergic gene expression in the striatum
Oleoylethanolamide attenuates cocaine-primed reinstatement and alters dopaminergic gene expression in the striatum
The lipid oleoylethanolamide (OEA) has been shown to affect reward-related behavior. However, there is limited experimenta...
Intra-hippocampal cis-P tau microinjection induces long-term changes in behavior and synaptic plasticity in mice
Intra-hippocampal cis-P tau microinjection induces long-term changes in behavior and synaptic plasticity in mice
Alzheimer's disease is accompanied by an abnormal high accumulation of cis-P tau. However, the long-term changes in be...
Inhibition of NLRP1 inflammasome improves autophagy dysfunction and Aβ disposition in APP/PS1 mice
Inhibition of NLRP1 inflammasome improves autophagy dysfunction and Aβ disposition in APP/PS1 mice
Increasing evidence has shown that the NOD-like receptor protein 1 (NLRP1) inflammasome is associated with Aβ generat...
Whole-body vibration ameliorates glial pathological changes in the hippocampus of hAPP transgenic mice, but does not affect plaque load
Whole-body vibration ameliorates glial pathological changes in the hippocampus of hAPP transgenic mice, but does not affect plaque load
Alzheimer’s disease (AD) is the core cause of dementia in elderly populations. One of the main hallmarks of AD is ex...
Distinct reinforcement learning profiles distinguish between language and attentional neurodevelopmental disorders
Distinct reinforcement learning profiles distinguish between language and attentional neurodevelopmental disorders
Theoretical models posit abnormalities in cortico-striatal pathways in two of the most common neurodevelopmental ...
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