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Combined Study of Behavior and Spike Discharges Associated with Negative Emotions in Mice
Combined Study of Behavior and Spike Discharges Associated with Negative Emotions in Mice
In modern society, people are increasingly exposed to chronic stress, leading to various mental disorders. However, the ac...
Suprachiasmatic Nucleus Vasoactive Intestinal Peptide Neurons Mediate Light-induced Transient Forgetting
Suprachiasmatic Nucleus Vasoactive Intestinal Peptide Neurons Mediate Light-induced Transient Forgetting
Our research reveals the critical role of the suprachiasmatic nucleus (SCN) vasoactive intestinal peptide (VIP) neurons in...
Hippocampal Oligodendrocytes Regulate Mossy Fiber Development Involved in Epileptic Responses
Hippocampal Oligodendrocytes Regulate Mossy Fiber Development Involved in Epileptic Responses
Although oligodendrocytes (OLs) are known to form the myelin sheath around neuronal axons for the saltatory conduction of ...
Into the Spotlight: Microglia in the Peripheral Nervous System
Into the Spotlight: Microglia in the Peripheral Nervous System
Prinz M, Jung S, Priller J. Microglia biology: One century of evolving concepts. Cell 2019, 179: 292–311.CAS  PubMed  ...
13-Docosenamide Enhances Oligodendrocyte Precursor Cell Differentiation USP33-Mediated Deubiquitination of CNR1 in Chronic Cerebral Hypoperfusion
13-Docosenamide Enhances Oligodendrocyte Precursor Cell Differentiation USP33-Mediated Deubiquitination of CNR1 in Chronic Cerebral Hypoperfusion
Chronic cerebral hypoperfusion leads to white matter injury (WMI), which plays a significant role in contributing to vascu...
Single-Cell Sequencing Reveals Circadian Sensitivity of Noise-Induced Hearing Loss Mediated by Macrophage-Driven NLRP3 Inflammasome Activation
Single-Cell Sequencing Reveals Circadian Sensitivity of Noise-Induced Hearing Loss Mediated by Macrophage-Driven NLRP3 Inflammasome Activation
Circadian sensitivity significantly influences the severity of noise-induced hearing loss (NIHL), but the underlying mecha...
Dissecting Social Working Memory: Neural and Behavioral Evidence for Externally and Internally Oriented Components
Dissecting Social Working Memory: Neural and Behavioral Evidence for Externally and Internally Oriented Components
Social working memory (SWM)—the ability to maintain and manipulate social information in the brain—plays a cru...
Temporal Variability Analysis of Cortical Blood Flow in Rats with Hyperacute Cerebral Ischemia
Temporal Variability Analysis of Cortical Blood Flow in Rats with Hyperacute Cerebral Ischemia
Cerebral ischemia restricts cerebral blood flow (CBF), leading to unstable hemodynamics. Past studies of ischemia mainly f...
Pre-action Neuronal Encoding of Task Situation Uncertainty in the Medial Prefrontal Cortex of Rats
Pre-action Neuronal Encoding of Task Situation Uncertainty in the Medial Prefrontal Cortex of Rats
Humans and animals have a fundamental ability to use experiences and environmental information to organize behavior. It of...
Mapping the Cross-species Brain Connectivity Atlas and Hemispheric Asymmetry of the Temporal Pole in Humans and Macaques
Mapping the Cross-species Brain Connectivity Atlas and Hemispheric Asymmetry of the Temporal Pole in Humans and Macaques
The temporal pole (TP), one of the most expanded cortical regions in humans relative to other primates, plays a crucial ro...
CGRP: Does A Novel Neuroimmune Modulator Facilitate Tissue Repair?
CGRP: Does A Novel Neuroimmune Modulator Facilitate Tissue Repair?
Deng L, Gillis JE, Chiu IM, Kaplan DH. Sensory neurons: An integrated component of innate immunity. Immunity 2024, 57: 815...
Neurotransmitter Switching: A Novel Mechanism for Fear Generalization
Neurotransmitter Switching: A Novel Mechanism for Fear Generalization
This research highlight was supported by the National Natural Science Foundation of China (81973639 and 81573712) and the ...
Unlocking the Mysteries of the Subcommissural Organ: A Patron Saint of Neuronal Development
Unlocking the Mysteries of the Subcommissural Organ: A Patron Saint of Neuronal Development
Kaur C, Ling EA. The circumventricular organs. Histol Histopathol 2017, 32: 879–892.PubMed  Googl...
Modulation of Nicotine-Associated Behaviour in Rats By μ-Opioid Signals from the Medial Prefrontal Cortex to the Nucleus Accumbens Shell
Modulation of Nicotine-Associated Behaviour in Rats By μ-Opioid Signals from the Medial Prefrontal Cortex to the Nucleus Accumbens Shell
Nicotine addiction is a concern worldwide. Most mechanistic investigations are on nicotine substance dependence properties...
Histaminergic Innervation of the Ventral Anterior Thalamic Nucleus Alleviates Motor Deficits in a 6-OHDA-Induced Rat Model of Parkinson’s Disease
Histaminergic Innervation of the Ventral Anterior Thalamic Nucleus Alleviates Motor Deficits in a 6-OHDA-Induced Rat Model of Parkinson’s Disease
The ventral anterior (VA) nucleus of the thalamus is a major target of the basal ganglia and is closely associated with th...
Time-Dependent Transcriptional Dynamics of Contextual Fear Memory Retrieval Reveals the Function of Dipeptidyl Peptidase 9 in Reconsolidation
Time-Dependent Transcriptional Dynamics of Contextual Fear Memory Retrieval Reveals the Function of Dipeptidyl Peptidase 9 in Reconsolidation
Numerous studies on the formation and consolidation of memory have shown that memory processes are characterized by phase-...
NG2 Glia: The Guardians Against Prion-induced Neurotoxicity Through Prostaglandin E2 Blockade
NG2 Glia: The Guardians Against Prion-induced Neurotoxicity Through Prostaglandin E2 Blockade
Liu Y, Guo J, Matoga M, Korotkova M, Jakobsson PJ, Aguzzi A. NG2 glia protect against prion neurotoxicity by inhibiting mi...
Correction to: Autophagy in Oligodendrocyte Lineage Cells Controls Oligodendrocyte Numbers and Myelin Integrity in an Age-dependent Manner
Correction to: Autophagy in Oligodendrocyte Lineage Cells Controls Oligodendrocyte Numbers and Myelin Integrity in an Age-dependent Manner
Hong Chen, Gang Yang, and De-En Xu have contributed equally to this work.Department of Neurology and Clinical Research Cen...
Role of the Thalamic Reticular Nucleus in Social Memory
Role of the Thalamic Reticular Nucleus in Social Memory
This highlight was supported by grants from the National Natural Science Foundation of China (32125018 and 32071005), Zhej...
Reprogramming miR-146b-snphb Signaling Activates Axonal Mitochondrial Transport in the Zebrafish M-cell and Facilitates Axon Regeneration After Injury
Reprogramming miR-146b-snphb Signaling Activates Axonal Mitochondrial Transport in the Zebrafish M-cell and Facilitates Axon Regeneration After Injury
Acute mitochondrial damage and the energy crisis following axonal injury highlight mitochondrial transport as an important...
A Novel Astrocyte-Neuron Interaction to Control Complex Animal Behavior
A Novel Astrocyte-Neuron Interaction to Control Complex Animal Behavior
Zhou X, Xiao Q, Liu Y, Chen S, Xu X, Zhang Z. Astrocyte-mediated regulation of BLAWFS1 neurons alleviates risk-assessment ...
The Current State and Future Outlook of PET Tracers for AMPA Receptors
The Current State and Future Outlook of PET Tracers for AMPA Receptors
Cao YY, Wu LL, Li XN, Yuan YL, Zhao WW, Qi JX. Molecular mechanisms of AMPA receptor trafficking in the nervous system. In...
Dysregulation of Iron Homeostasis Mediated by FTH Increases Ferroptosis Sensitivity in TP53-Mutant Glioblastoma
Dysregulation of Iron Homeostasis Mediated by FTH Increases Ferroptosis Sensitivity in TP53-Mutant Glioblastoma
Iron metabolism is a critical factor in tumorigenesis and development. Although TP53 mutations are prevalent in glioblasto...
Inhibition of the cGAS‑STING Pathway Reduces Cisplatin-Induced Inner Ear Hair Cell Damage
Inhibition of the cGAS‑STING Pathway Reduces Cisplatin-Induced Inner Ear Hair Cell Damage
Although cisplatin is a widely used chemotherapeutic agent, it is severely toxic and causes irreversible hearing loss, res...
Deciphering the Role of Shank3 in Dendritic Morphology and Synaptic Function Across Postnatal Developmental Stages in the Shank3B KO Mouse
Deciphering the Role of Shank3 in Dendritic Morphology and Synaptic Function Across Postnatal Developmental Stages in the Shank3B KO Mouse
Autism Spectrum Disorder (ASD) is marked by early-onset neurodevelopmental anomalies, yet the temporal dynamics of genetic...
Neuronal Regulation of Feeding and Energy Metabolism: A Focus on the Hypothalamus and Brainstem
Neuronal Regulation of Feeding and Energy Metabolism: A Focus on the Hypothalamus and Brainstem
In the face of constantly changing environments, the central nervous system (CNS) rapidly and accurately calculates the bo...
Neural and Behavioral Measures of Stress-induced Impairment in Error Awareness and Post-error Adjustment
Neural and Behavioral Measures of Stress-induced Impairment in Error Awareness and Post-error Adjustment
Exposure to stress negatively affects error processing, but the impact of stress on error awareness remains to be determin...
Knockdown of SIRT2 Rescues YARS-induced Charcot-Marie-Tooth Neuropathy in Drosophila
Knockdown of SIRT2 Rescues YARS-induced Charcot-Marie-Tooth Neuropathy in Drosophila
Catala M, Kubis N. Gross anatomy and development of the peripheral nervous system. Handb Clin Neurol 2013, 115: 29–41.Arti...
Three-phase Enriched Environment Improves Post-stroke Gait Dysfunction via Facilitating Neuronal Plasticity in the Bilateral Sensorimotor Cortex: A Multimodal MRI/PET Analysis in Rats
Three-phase Enriched Environment Improves Post-stroke Gait Dysfunction via Facilitating Neuronal Plasticity in the Bilateral Sensorimotor Cortex: A Multimodal MRI/PET Analysis in Rats
The three-phase Enriched Environment (EE) paradigm has been shown to promote post-stroke functional improvement, but the n...
The Role of KDM2A and H3K36me2 Demethylation in Modulating MAPK Signaling During Neurodevelopment
The Role of KDM2A and H3K36me2 Demethylation in Modulating MAPK Signaling During Neurodevelopment
Intellectual disability (ID) is a condition characterized by cognitive impairment and difficulties in adaptive functioning...
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