Tatum WO. Mesial temporal lobe epilepsy. J Clin Neurophysiol 2012, 29: 356–365.

PubMed  Google Scholar 

Cheng H, Lou Q, Wang Y, Chen Z. Double-edged mossy cells in temporal lobe epilepsy: Evil in the early stage through a BDNF-dependent strengthening dentate gyrus circuit. Neurosci Bull 2023, 39: 1031–1033.

PubMed  PubMed Central  Google Scholar 

Löscher W, Klitgaard H, Twyman RE, Schmidt D. New avenues for anti-epileptic drug discovery and development. Nat Rev Drug Discov 2013, 12: 757–776.

PubMed  Google Scholar 

Wang Y, Chen Z. An update for epilepsy research and antiepileptic drug development: Toward precise circuit therapy. Pharmacol Ther 2019, 201: 77–93.

CAS  PubMed  Google Scholar 

Anne Martin E, Woodruff D, Rawson RL, Williams ME. Examining hippocampal mossy fiber synapses by 3D electron microscopy in wildtype and Kirrel3 knockout mice. eNeuro 2017, 4: ENEURO.0088–17.2017.

Deng W, Aimone JB, Gage FH. New neurons and new memories: How does adult hippocampal neurogenesis affect learning and memory? Nat Rev Neurosci 2010, 11: 339–350.

CAS  PubMed  PubMed Central  Google Scholar 

Krebs J, Römer B, Overall RW, Fabel K, Babu H, Brandt MD. Adult hippocampal neurogenesis and plasticity in the infrapyramidal bundle of the mossy fiber projection: II. genetic covariation and identification of Nos1 as linking candidate gene. Front Neurosci 2011, 5: 106.

PubMed  PubMed Central  Google Scholar 

Bagri A, Cheng HJ, Yaron A, Pleasure SJ, Tessier-Lavigne M. Stereotyped pruning of long hippocampal axon branches triggered by retraction inducers of the semaphorin family. Cell 2003, 113: 285–299.

CAS  PubMed  Google Scholar 

Li W, Allen ME, Rui Y, Ku L, Liu G, Bankston AN, et al. p39 is responsible for increasing Cdk5 activity during postnatal neuron differentiation and governs neuronal network formation and epileptic responses. J Neurosci 2016, 36: 11283–11294.

CAS  PubMed  PubMed Central  Google Scholar 

Nave KA. Myelination and support of axonal integrity by Glia. Nature 2010, 468: 244–252.

CAS  PubMed  Google Scholar 

Xin W, Mironova YA, Shen H, Marino RAM, Waisman A, Lamers WH, et al. Oligodendrocytes support neuronal glutamatergic transmission via expression of glutamine synthetase. Cell Rep 2019, 27: 2262-2271.e5.

CAS  PubMed  PubMed Central  Google Scholar 

Woolf CJ, Bloechlinger S. Neuroscience. it takes more than two to nogo. Science 2002, 297: 1132–1134.

CAS  PubMed  Google Scholar 

Meier S, Bräuer AU, Heimrich B, Nitsch R, Savaskan NE. Myelination in the hippocampus during development and following lesion. Cell Mol Life Sci 2004, 61: 1082–1094.

CAS  PubMed  PubMed Central  Google Scholar 

Savaskan NE, Plaschke M, Ninnemann O, Spillmann AA, Schwab ME, Nitsch R, et al. Myelin does not influence the choice behaviour of entorhinal axons but strongly inhibits their outgrowth length in vitro. Eur J Neurosci 1999, 11: 316–326.

CAS  PubMed  Google Scholar 

Liu J, Dietz K, DeLoyht JM, Pedre X, Kelkar D, Kaur J, et al. Impaired adult myelination in the prefrontal cortex of socially isolated mice. Nat Neurosci 2012, 15: 1621–1623.

CAS  PubMed  PubMed Central  Google Scholar 

Jiang C, Qiu W, Yang Y, Huang H, Dai ZM, Yang A, et al. ADAMTS4 enhances oligodendrocyte differentiation and remyelination by cleaving NG2 proteoglycan and attenuating PDGFR α signaling. J Neurosci 2023, 43: 4405–4417.

CAS  PubMed  PubMed Central  Google Scholar 

Richard LuQ, Sun T, Zhu Z, Ma N, Garcia M, Stiles CD, et al. Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. Cell 2002, 109: 75–86.

Google Scholar 

Mallon BS, Macklin WB. Overexpression of the 3’-untranslated region of myelin proteolipid protein mRNA leads to reduced expression of endogenous proteolipid mRNA. Neurochem Res 2002, 27: 1349–1360.

CAS  PubMed  Google Scholar 

Mallon BS, Elizabeth Shick H, Kidd GJ, Macklin WB. Proteolipid promoter activity distinguishes two populations of NG2-positive cells throughout neonatal cortical development. J Neurosci 2002, 22: 876–885.

CAS  PubMed  PubMed Central  Google Scholar 

Tripathi RB, Clarke LE, Burzomato V, Kessaris N, Anderson PN, Attwell D, et al. Dorsally and ventrally derived oligodendrocytes have similar electrical properties but myelinate preferred tracts. J Neurosci 2011, 31: 6809–6819.

CAS  PubMed  PubMed Central  Google Scholar 

Rojas A, Gueorguieva P, Lelutiu N, Quan Y, Shaw R, Dingledine R. The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus. Neurobiol Dis 2014, 70: 74–89.

CAS  PubMed  PubMed Central  Google Scholar 

Koenning M, Jackson S, Hay CM, Faux C, Kilpatrick TJ, Willingham M, et al. Myelin gene regulatory factor is required for maintenance of myelin and mature oligodendrocyte identity in the adult CNS. J Neurosci 2012, 32: 12528–12542.

CAS  PubMed  PubMed Central  Google Scholar 

Lynd-Balta E, Pilcher WH, Joseph SA. AMPA receptor alterations precede mossy fiber sprouting in young children with temporal lobe epilepsy. Neuroscience 2004, 126: 105–114.

CAS  PubMed  Google Scholar 

Houser CR, Miyashiro JE, Swartz BE, Walsh GO, Rich JR, Delgado-Escueta AV. Altered patterns of dynorphin immunoreactivity suggest mossy fiber reorganization in human hippocampal epilepsy. J Neurosci 1990, 10: 267–282.

CAS  PubMed  PubMed Central  Google Scholar 

Morimoto K, Fahnestock M, Racine RJ. Kindling and status epilepticus models of epilepsy: Rewiring the brain. Prog Neurobiol 2004, 73: 1–60.

CAS  PubMed  Google Scholar 

Rakhade SN, Jensen FE. Epileptogenesis in the immature brain: Emerging mechanisms. Nat Rev Neurol 2009, 5: 380–391.

CAS  PubMed  PubMed Central  Google Scholar 

Cavarsan CF, Malheiros J, Hamani C, Najm I, Covolan L. Is mossy fiber sprouting a potential therapeutic target for epilepsy? Front Neurol 2018, 9: 1023.

PubMed  PubMed Central  Google Scholar 

Siebert JR, Osterhout DJ. The inhibitory effects of chondroitin sulfate proteoglycans on oligodendrocytes. J Neurochem 2011, 119: 176–188.

CAS  PubMed  Google Scholar 

Giger RJ, Venkatesh K, Chivatakarn O, Raiker SJ, Robak L, Hofer T, et al. Mechanisms of CNS myelin inhibition: Evidence for distinct and neuronal cell type specific receptor systems. Restor Neurol Neurosci 2008, 26: 97–115.

PubMed  PubMed Central  Google Scholar 

Cao Z, Gao Y, Deng K, Williams G, Doherty P, Walsh FS. Receptors for myelin inhibitors: Structures and therapeutic opportunities. Mol Cell Neurosci 2010, 43: 1–14.

CAS  PubMed  Google Scholar 

Lee JK, Geoffroy CG, Chan AF, Tolentino KE, Crawford MJ, Leal MA, et al. Assessing spinal axon regeneration and sprouting in Nogo-, MAG-, and OMgp-deficient mice. Neuron 2010, 66: 663–670.

CAS  PubMed  PubMed Central  Google Scholar 

Wang KC, Koprivica V, Kim JA, Sivasankaran R, Guo Y, Neve RL, et al. Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth. Nature 2002, 417: 941–944.

CAS  PubMed  Google Scholar 

Atwal JK, Pinkston-Gosse J, Syken J, Stawicki S, Wu Y, Shatz C, et al. PirB is a functional receptor for myelin inhibitors of axonal regeneration. Science 2008, 322: 967–970.

CAS  PubMed  Google Scholar 

Fujita Y, Endo S, Takai T, Yamashita T. Myelin suppresses axon regeneration by PIR-B/SHP-mediated inhibition of Trk activity. EMBO J 2011, 30: 1389–1401.

CAS  PubMed  PubMed Central  Google Scholar 

Mei F, Fancy SPJ, Shen YA, Niu J, Zhao C, Presley B, et al. Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis. Nat Med 2014, 20: 954–960.

CAS  PubMed  PubMed Central  Google Scholar 

Wang F, Yang YJ, Yang N, Chen XJ, Huang NX, Zhang J, et al. Enhancing oligodendrocyte myelination rescues synaptic loss and improves functional recovery after chronic hypoxia. Neuron 2018, 99: 689-701.e5.

CAS  PubMed  PubMed Central  Google Scholar