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Ameliorative Effect of Curcumin on Long-Term Potentiation Impaired in Adult-Onset Hypothyroidism
Ameliorative Effect of Curcumin on Long-Term Potentiation Impaired in Adult-Onset Hypothyroidism
Thyroid hormone dysfunction may affect intracellular signaling cascades and have a role in regulating cognitive function, ...
Neuroprotective Effects of Curcumin in Acute Ischemic Stroke: Insights of Preclinical and Clinical Studies
Neuroprotective Effects of Curcumin in Acute Ischemic Stroke: Insights of Preclinical and Clinical Studies
Curcumin, The Golden Spice dates long back for the history of having medicinal effects in traditional practices like Ayurv...
Role of miR-30e-5p in the Occurrence and Development of Posterior Circulation Ischemic Stroke
Role of miR-30e-5p in the Occurrence and Development of Posterior Circulation Ischemic Stroke
Posterior circulation ischemic stroke (PCIS) is caused by occlusion of the vertebral basilar artery, with complex and dive...
Assessment of the Causality between Uric Acid and Epilepsy: Bidirectional Two-Sample Mendelian Randomization
Assessment of the Causality between Uric Acid and Epilepsy: Bidirectional Two-Sample Mendelian Randomization
Uric acid (UA) is essential in the physiological and pathophysiological processes of various diseases. The linkage between...
Investigating the Therapeutic Potential of Maharasnadi Kwath Constituents Against HTT Proteins in Huntington’s Disease: An In-Silico Pharmacological Approach
Investigating the Therapeutic Potential of Maharasnadi Kwath Constituents Against HTT Proteins in Huntington’s Disease: An In-Silico Pharmacological Approach
Huntington’s disease (HD) is a severe neurodegenerative disease marked by the progressive degradation of nerve cells...
Serotonin Receptors as a Potential Therapeutic Target in Epilepsy
Serotonin Receptors as a Potential Therapeutic Target in Epilepsy
The development of antiepileptic drugs has focused particularly on neurotransmitters involved in excitatory and inhibitory...
Effects of Ghrelin on Brain and Serum Inflammatory Parameters in PTZ-Kindling Model in Rats
Effects of Ghrelin on Brain and Serum Inflammatory Parameters in PTZ-Kindling Model in Rats
It is well known that inflammation has a significant function in the pathophysiology of epilepsy. This research study that...
Vitamin C Mitigates Neuronal Injury and Cognitive Impairment in Epileptic Rats Induced by Lithium Chloride–Pilocarpine Hydrochloride through Autophagy Regulation
Vitamin C Mitigates Neuronal Injury and Cognitive Impairment in Epileptic Rats Induced by Lithium Chloride–Pilocarpine Hydrochloride through Autophagy Regulation
Vitamin C, a crucial antioxidant, plays a significant role in various physiological processes like antioxidation, anti-inf...
Predictive Value of miR-574-5p in Acute Cerebral Infarction Combined with Obstructive Sleep Apnea Syndrome
Predictive Value of miR-574-5p in Acute Cerebral Infarction Combined with Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea syndrome (OSAS) is a prevalent comorbidity in patients with acute cerebral infarction (ACI). This ...
Expression of Farnesylated EGFP in Primary Cultures of Neocortical Neurons Disrupts Dendritic Spine Development
Expression of Farnesylated EGFP in Primary Cultures of Neocortical Neurons Disrupts Dendritic Spine Development
Genetically encoded fluorescent proteins are widely used in biological research in general and in neurobiology in particul...
Possible Neuroprotective Effect of tDCS on Doxorubicin-Induced Neurotoxicity in Rats
Possible Neuroprotective Effect of tDCS on Doxorubicin-Induced Neurotoxicity in Rats
Doxorubicin (DOX), a chemotherapeutic medicine, are frequently utilized to treat various malignancies, even though it has ...
Olfactory Bulbectomy in Mice Induces an Increase in Hippocampal Pro-Nerve Growth Factor Protein Levels
Olfactory Bulbectomy in Mice Induces an Increase in Hippocampal Pro-Nerve Growth Factor Protein Levels
Olfactory bulbectomy in rodents is a wide-used model of cholinergic dysfunction, yet, the state of nerve growth factor sys...
Mechanistic Effects of Polyphenols against Anesthesia-Induced Neurotoxicity: A Systematic Review
Mechanistic Effects of Polyphenols against Anesthesia-Induced Neurotoxicity: A Systematic Review
General anesthetics in some patients may lead to neurotoxic complications, including apoptosis in neuronal cells and posto...
Diagnostic Significance of Serum miR-483-5p in Cerebrovascular Disease and Its Role in the Prognosis of Interventional Therapy
Diagnostic Significance of Serum miR-483-5p in Cerebrovascular Disease and Its Role in the Prognosis of Interventional Therapy
Cerebrovascular disease (CVD) represents the primary contributor to disability and premature mortality among the populatio...
Phenotypic and Genotypic Landscape of Epileptic Encephalopathies in Children with Seven Novel Variants: A Single Tertiary Care Hospital Experience
Phenotypic and Genotypic Landscape of Epileptic Encephalopathies in Children with Seven Novel Variants: A Single Tertiary Care Hospital Experience
Developmental and epileptic encephalopathy (DEE) encompasses severe epilepsies with early-onset seizures, typically within...
Expression of CD200 and Its Influences on Epileptogenesis in a Mouse Model of Focal Cortical Dysplasia
Expression of CD200 and Its Influences on Epileptogenesis in a Mouse Model of Focal Cortical Dysplasia
Focal cortical dysplasia (FCD) is one of the major causes of refractory epilepsy. Evidence suggests that neuroinflammation...
Pleiotrophin: A Key Player in the Pathophysiology of Aneurysmal Subarachnoid Hemorrhage?
Pleiotrophin: A Key Player in the Pathophysiology of Aneurysmal Subarachnoid Hemorrhage?
This study aims to investigate the levels of pleiotrophin (PTN) in patients with aneurysmal subarachnoid hemorrhage (SAH) ...
Genetic Association of microRNA-137 Polymorphism with the Susceptibility of Acute Ischemic Stroke in the Chinese Han Population
Genetic Association of microRNA-137 Polymorphism with the Susceptibility of Acute Ischemic Stroke in the Chinese Han Population
Accumulating research have suggested the involvement of genetic polymorphisms in microRNAs in the susceptibility of acute ...
Prenatal Ruxolitinib Treatment Improved Muscle Strength but Showed No Impact on the Neurobehavioral and Electrophysiological Traits in Adult Mice
Prenatal Ruxolitinib Treatment Improved Muscle Strength but Showed No Impact on the Neurobehavioral and Electrophysiological Traits in Adult Mice
The JAK/STAT signalling pathway is essential for cell communication and gene expression, particularly in brain development...
Noscapine Down-Regulates LPS-Induced Neuroinflammation in BV-2 Microglia Cells via Modulation of MAPK and NF-κB Signaling Pathways
Noscapine Down-Regulates LPS-Induced Neuroinflammation in BV-2 Microglia Cells via Modulation of MAPK and NF-κB Signaling Pathways
Noscapine is widely used to prevent stroke, glioblastoma, and anxiety. The aim of this study was to investigate the anti-n...
Clinical Value of lncRNA MALAT1 and miR-154-5p in the Severity and Prognosis of Convulsive Status Epilepticus
Clinical Value of lncRNA MALAT1 and miR-154-5p in the Severity and Prognosis of Convulsive Status Epilepticus
Convulsive status epilepticus (CSE) is a common pediatric emergency that can lead to irreversible brain damage and high mo...
Establishment of Neurofilament Light Chain in Plasma-Derived Neuronal Extracellular Vesicles as a Biomarker for Disease Progression in Multiple Sclerosis Patients
Establishment of Neurofilament Light Chain in Plasma-Derived Neuronal Extracellular Vesicles as a Biomarker for Disease Progression in Multiple Sclerosis Patients
Multiple sclerosis (MS) is a complex neurological disorder. Neurofilament light chain (NfL) is a marker of axonal injury. ...
S100B, GFAP and NSE: The Role of Neuro Biomarkers for Early Predictors of Cerebral Vaso-Occlusive Manifestations of Sickle Cell Disease
S100B, GFAP and NSE: The Role of Neuro Biomarkers for Early Predictors of Cerebral Vaso-Occlusive Manifestations of Sickle Cell Disease
Hemoglobinopathies are commonly occurring genetic disorders worldwide. The aim of this study is to determine the biochemic...
Evaluation of the Low-Energy Ultrashort Pulsed Electron Beam Irradiation-Induced Oxidative Stress and Adaptive Response of Select Enzymes in a Rat Brain
Evaluation of the Low-Energy Ultrashort Pulsed Electron Beam Irradiation-Induced Oxidative Stress and Adaptive Response of Select Enzymes in a Rat Brain
The aim of this study is to evaluate the dynamics of oxidative stress (OS) development, as well as adaptive response of se...
Exploring Mitochondrial Quality in Aging and Neurodegenerative Diseases
Exploring Mitochondrial Quality in Aging and Neurodegenerative Diseases
Aging is a gradual process characterized by a decline in cellular and tissue function, significantly contributing to the d...
The Correlation between NLR and PLR and the Occurrence and Prognosis of PHI in Patients with Traumatic Brain Injury
The Correlation between NLR and PLR and the Occurrence and Prognosis of PHI in Patients with Traumatic Brain Injury
The purpose of this retrospective study was to investigate the risk factors associated with progressive hemorrhagic injury...
Possible Mechanism for Perception of Auditory-Verbal Hallucinations in Schizophrenia and Approaches to Their Weakening
Possible Mechanism for Perception of Auditory-Verbal Hallucinations in Schizophrenia and Approaches to Their Weakening
We put forward a hypothesis that the processing and perception of auditory-verbal hallucinations in schizophrenia such as ...
A Systematic Review on the Effectiveness of Trigonelline, Safranal and Chamomile in Cure and Prevention of Alzheimer’s Disease and Dementia
A Systematic Review on the Effectiveness of Trigonelline, Safranal and Chamomile in Cure and Prevention of Alzheimer’s Disease and Dementia
Alzheimer’s disease and dementia are neurodegenerative conditions characterized by memory loss and diminished capaci...
Exploring the Role of TRP Channels and Neurotrophic Factors in Epileptogenesis: Insights from Diverse Seizure Models
Exploring the Role of TRP Channels and Neurotrophic Factors in Epileptogenesis: Insights from Diverse Seizure Models
Epilepsy affects many people globally and results from disrupted neuron balance, causing abnormal central nervous system e...
miR-92b-3p Regulates Cell Progression and Drug Resistance through Upregulation of CXCL5 in Glioma
miR-92b-3p Regulates Cell Progression and Drug Resistance through Upregulation of CXCL5 in Glioma
As malignant central nervous system tumors, glioma have strong aggressiveness and drug resistance, which reduces the survi...
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