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Aberrant functional connectome gradient and its neurotransmitter basis in Parkinson's disease
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CRISPR-based epigenetic editing of Gad1 improves synaptic inhibition and cognitive behavior in a Tauopathy mouse model
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Sporadic ALS hiPSC-derived motor neurons show axonal defects linked to altered axon guidance pathways
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Cerebellar lipid dysregulation in SCA3: A comparative study in patients and mice
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Whole transcriptome analysis of unmutated sporadic ALS patients' peripheral blood reveals phenotype-specific gene expression signature
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Glymphatic dysfunction and neurodegeneration in ALS: Longitudinal insights from rNLS8 TDP-43 mice
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Unravelling a mechanistic link between mitophagy defect, mitochondrial malfunction, and apoptotic neurodegeneration in Mucopolysaccharidosis VII
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Nrf2 phosphorylation contributes to acquisition of pericyte reprogramming via the PKCδ pathway
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Binding of HCN channels to GABAB receptors in dopamine neurons of the VTA limits synaptic inhibition and prevents the development of anxiety
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Microglia TRPC1 SUMOylation drives neuroinflammation after stroke by modulating NLRP3 activity via increasing TRPC1 interaction with ARRB2
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GrpEL1 overexpression mitigates hippocampal neuron damage via mitochondrial unfolded protein response after experimental status epilepticus
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Elucidating cortical neurovascular involvement in Huntington's disease using human brain tissue microarrays
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Brain acid sphingomyelinase controls addiction-related behaviours in a sex-specific way
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S100A9 protein activates microglia and stimulates phagocytosis, resulting in synaptic and neuronal loss
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Current safety recommendations for handling mouse and human αsynuclein pre-formed fibrils
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Effects of trace element dysregulation on brain structure and function in spinocerebellar Ataxia type 3
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Attenuated neurotoxicity after repeated methamphetamine binges linked to dopamine transporter (DAT) decline
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Long-term exposure to anti-GluA3 antibodies triggers functional and structural changes in hippocampal neurons
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Impairment in the homeostatic recruitment of layer 5/6 neurons following whisker stimulation in Fmr1 KO mice
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iPSC models of mitochondrial diseases
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Harmonization of CSF and imaging biomarkers for Alzheimer's disease: Need and practical applications for genetics studies and preclinical classification
Harmonization of CSF and imaging biomarkers for Alzheimer's disease: Need and practical applications for genetics studies and preclinical classification
In Alzheimer's disease (AD) research, cerebrospinal fluid (CSF) Amyloid beta (Aβ), Tau and pTau are the most accepted and ...
The effects of P2 segment of posterior cerebral artery to thalamus blood supply pattern on gait in cerebral small vessel disease: A 7 T MRI based study
The effects of P2 segment of posterior cerebral artery to thalamus blood supply pattern on gait in cerebral small vessel disease: A 7 T MRI based study
Keywords7 T MRIThalamusCerebral small vessel diseasePosterior cerebral arteryGaitAbbreviationsAAL3automated anatomical lab...
Differential profiles of serum cytokines in Parkinson's disease according to disease duration
Differential profiles of serum cytokines in Parkinson's disease according to disease duration
ObjectiveNeurodegeneration and neuroinflammation are two intertwined mechanisms contributing to the pathophysiology of Par...
PI3K signaling promotes formation of lipid-laden foamy macrophages at the spinal cord injury site
PI3K signaling promotes formation of lipid-laden foamy macrophages at the spinal cord injury site
After spinal cord injury (SCI), infiltrating macrophages undergo excessive phagocytosis of myelin and cellular debris, for...
Predicting neurodegeneration from sleep related biofluid changes
Predicting neurodegeneration from sleep related biofluid changes
Sleep-wake disturbances are common in neurodegenerative diseases and may occur years before the clinical diagnosis, potent...
Antisense oligonucleotide-mediated disruption of HTT caspase-6 cleavage site ameliorates the phenotype of YAC128 Huntington disease mice
Antisense oligonucleotide-mediated disruption of HTT caspase-6 cleavage site ameliorates the phenotype of YAC128 Huntington disease mice
KeywordsHuntington diseaseYAC128 miceAntisense oligonucleotidesCaspase-6RNA splicingRNA sequence analysisMRIAbbreviationsa...
Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing
Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing
KeywordsNeurodegenerationX-linked dystonia parkinsonism diseaseInduced pluripotent stem cellsMedium spiny neuronsQuantitat...
External segment of the globus pallidus in health and disease: Its interactions with the striatum and subthalamic nucleus
External segment of the globus pallidus in health and disease: Its interactions with the striatum and subthalamic nucleus
KeywordsExternal segment of the globus pallidusStriatumSubthalamic nucleusParkinson's diseaseMovement disordersDeep brain ...
Characterisation and prion transmission study in mice with genetic reduction of sporadic Creutzfeldt-Jakob disease risk gene Stx6
Characterisation and prion transmission study in mice with genetic reduction of sporadic Creutzfeldt-Jakob disease risk gene Stx6
KeywordsPrion diseaseCreutzfeldt-Jakob diseaseSNARESyntaxin-6Incubation periodAbbreviationssCJDsporadic Creutzfeldt-Jakob ...
Ganglioglioma cells potentiate neuronal network synchronicity and elicit burst discharges via released factors
Ganglioglioma cells potentiate neuronal network synchronicity and elicit burst discharges via released factors
Gangliogliomas (GGs) represent the most frequent glioneuronal tumor entity associated with chronic recurrent seizures; rar...
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