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Methylphenidate and sustained attention in rats: a systematic review
Methylphenidate and sustained attention in rats: a systematic review
Methylphenidate (MPH) is widely used to study attentional processes in animal models, particularly in rats, due to the con...
Aggression and repeated alcohol drinking-in-the-dark: dissecting subtypes in outbred mice
Aggression and repeated alcohol drinking-in-the-dark: dissecting subtypes in outbred mice
Repeated bouts of alcohol consumption increase the risk for developing alcohol use disorders and influence social dynamics...
Update on pharmacogenomic approaches in the treatment of autism spectrum disorders
Update on pharmacogenomic approaches in the treatment of autism spectrum disorders
A variety of neurodevelopmental disorders collectively referred to as autism spectrum disorders (ASD) are characterized by...
Taurine attenuates arsenic-induced neurotoxicity through modulation of gut microbiota structure
Taurine attenuates arsenic-induced neurotoxicity through modulation of gut microbiota structure
Memory decline (MD) and anxiety/depression-like behavior (ADB) are multisystem diseases involving gastrointestinal and mic...
Perinatal exposure to delta-9-tetrahydrocannabinol (THC) alters goal-directed behavior and dopamine functioning in wistar rats
Perinatal exposure to delta-9-tetrahydrocannabinol (THC) alters goal-directed behavior and dopamine functioning in wistar rats
Cannabis use during 2021pregnancy is common as many pregnant women consider cannabis as a safe way to alleviate symptoms a...
Differential effects of adolescent fatty acid amide hydrolase and monoacylglycerol lipase inhibition on adolescent and adult behaviors in male rats
Differential effects of adolescent fatty acid amide hydrolase and monoacylglycerol lipase inhibition on adolescent and adult behaviors in male rats
Endocannabinoid signaling during adolescence plays a critical role in brain development and shapes both healthy and malada...
State and trait serotonin variations interact to shape the intrinsic connectivity and gradient architecture of the brain – a combined TPH2 genetics and tryptophan depletion study in men
State and trait serotonin variations interact to shape the intrinsic connectivity and gradient architecture of the brain – a combined TPH2 genetics and tryptophan depletion study in men
Serotonin (5-HT) critically regulates cognitive and emotional functions, and both stable and transient variations in 5-HT ...
PKMζ in the prefrontal cortex alters cocaine cue-induced reinstatement in a sex-specific manner
PKMζ in the prefrontal cortex alters cocaine cue-induced reinstatement in a sex-specific manner
Cocaine alters glutamate in the prefrontal cortex (PFC), which is a region critical for mediating relapse behaviors. Long-...
Decoding behavioral economics vs. traditional dose response functions in rodent intravenous drug self-administration procedures
Decoding behavioral economics vs. traditional dose response functions in rodent intravenous drug self-administration procedures
Behavioral economics (BE), as applied to intravenous drug self-administration (IVSA) procedures in animals, has been haile...
Methadone maintenance therapy alters the expression of PLK1 and IFIH1 in patients with heroin addiction: a case-control study
Methadone maintenance therapy alters the expression of PLK1 and IFIH1 in patients with heroin addiction: a case-control study
Heroin addiction poses a significant threat to public health. Methadone maintenance therapy (MMT) is one of the effective ...
Social context in renewal of cocaine and fentanyl seeking: role of peer presence versus peer absence
Social context in renewal of cocaine and fentanyl seeking: role of peer presence versus peer absence
Drug relapse among individuals with substance use disorders can be triggered by social cues that were present in the origi...
Alpha-pinene modulates hippocampal MAPKs/c-Fos pathways during morphine dependence and withdrawal in rats
Alpha-pinene modulates hippocampal MAPKs/c-Fos pathways during morphine dependence and withdrawal in rats
A potential strategy for managing morphine addiction is preventing mitogen-activated protein kinases (MAPKs) activation an...
Methylphenidate reduces rats’ temporal discounting of aversive outcomes
Methylphenidate reduces rats’ temporal discounting of aversive outcomes
Understanding the impact of delayed consequences on decision-making is a scientific goal with important clinical implicati...
Dissecting the role of mineralocorticoid receptors in binge-like alcohol drinking in mice: Finerenone as a potential pharmacotherapy
Dissecting the role of mineralocorticoid receptors in binge-like alcohol drinking in mice: Finerenone as a potential pharmacotherapy
Alcohol use disorder (AUD) is a serious public health issue, for which only few pharmacological treatments are currently a...
A repeated low-dose regimen of MDMA has transient next-day effects on locomotor activity, anxiety-like behavior, and brain serotonin levels, with no effect on anhedonia-like behavior, in both female and male rats
A repeated low-dose regimen of MDMA has transient next-day effects on locomotor activity, anxiety-like behavior, and brain serotonin levels, with no effect on anhedonia-like behavior, in both female and male rats
MDMA (3–4 methylenedioxymethamphetamine) assisted psychotherapy has gained considerable attention as a potential adj...
Acute apocynin-tandospirone derivatives (ATDs) exacerbate methamphetamine-induced hyperlocomotion in rats
Acute apocynin-tandospirone derivatives (ATDs) exacerbate methamphetamine-induced hyperlocomotion in rats
Apocynin–tandospirone derivatives (ATDs) have recently been shown to ameliorate methamphetamine (MAP)-induced behavi...
Dopamine receptor sensitivity, cocaine-induced behaviors, and Pavlovian conditioned approach in male rats
Dopamine receptor sensitivity, cocaine-induced behaviors, and Pavlovian conditioned approach in male rats
Understanding the determinants of individual differences in cue-reactivity and drug sensitivity is critical to identifying...
The effect of cannabis use on the time course of positive and negative affect in the daily life of youth
The effect of cannabis use on the time course of positive and negative affect in the daily life of youth
Contemporary theories of addiction postulate that persistent cannabis use develops in part through the positive and negati...
Divergent outcomes of delta 9 – tetrahydrocannabinol (THC) in adolescence on mesocortical dopamine and cognitive development in male and female mice
Divergent outcomes of delta 9 – tetrahydrocannabinol (THC) in adolescence on mesocortical dopamine and cognitive development in male and female mice
The increasing exposure to delta 9-tetrahydrocannabinol (THC) in youth sparks concerns about disruption of ongoing neurode...
Branched-chain amino acids and risk of major depressive disorder: a Mendelian randomization and colocalization study
Branched-chain amino acids and risk of major depressive disorder: a Mendelian randomization and colocalization study
Depression is associated with numerous metabolic pathway abnormalities, and several studies have suggested a link between ...
Chemogenetic activation of medial prefrontal cortex projections to the nucleus accumbens shell suppresses cocaine-primed reinstatement in EcoHIV infected mice
Chemogenetic activation of medial prefrontal cortex projections to the nucleus accumbens shell suppresses cocaine-primed reinstatement in EcoHIV infected mice
HIV is highly comorbid with cocaine use disorder (CUD). Relapse is a major challenge in the treatment of CUD, and people l...
Effect of genetic deletion of nociceptin/orphanin FQ receptors on spatial and associative memory in rats
Effect of genetic deletion of nociceptin/orphanin FQ receptors on spatial and associative memory in rats
A growing body of evidence suggests that the N/OFQ-NOP receptor system modulates learning and memory in rodents, with NOP ...
Transmembrane AMPA receptor regulatory protein TARP ɣ-8 is a target of ethanol that regulates self-administration and relapse in mice
Transmembrane AMPA receptor regulatory protein TARP ɣ-8 is a target of ethanol that regulates self-administration and relapse in mice
Behavioral pathologies that characterize alcohol use disorder (AUD) are driven by the powerful reinforcing, or rewarding, ...
Post-methamphetamine working memory decline predicts relapse vulnerability in rats and is rescued by mGlu3 receptor activation
Post-methamphetamine working memory decline predicts relapse vulnerability in rats and is rescued by mGlu3 receptor activation
Widespread methamphetamine (meth) misuse remains a worldwide public health issue that lacks effective clinical treatment. ...
The impact of anti-craving medication on cue reactivity and abstinence in patients undergoing alcohol detoxification: some preliminary evidence from a retrospective event-related potentials study
The impact of anti-craving medication on cue reactivity and abstinence in patients undergoing alcohol detoxification: some preliminary evidence from a retrospective event-related potentials study
While medications such as acamprosate, baclofen, or naltrexone have shown promising effects in the treatment of alcohol us...
Semaglutide, tirzepatide, and retatrutide attenuate the interoceptive effects of alcohol in male and female rats
Semaglutide, tirzepatide, and retatrutide attenuate the interoceptive effects of alcohol in male and female rats
Alcohol use disorder (AUD) remains a major public health challenge, yet effective pharmacotherapies are limited. As such, ...
96-h methamphetamine self-administration elicits striatal dopamine depletion in male and female rats: a model of binge-like use
96-h methamphetamine self-administration elicits striatal dopamine depletion in male and female rats: a model of binge-like use
Methamphetamine is a psychostimulant with significant public health implications. Chronic methamphetamine use is linked to...
Effects of acute alcohol administration on endocannabinoids and relation to subjective effects
Effects of acute alcohol administration on endocannabinoids and relation to subjective effects
Harmful alcohol use remains a significant global public health challenge. Examining variability in the acute subjective ef...
The influence of stress and social defeat on neurobiological reinforcement mechanisms across reward to withdrawal in nicotine addiction
The influence of stress and social defeat on neurobiological reinforcement mechanisms across reward to withdrawal in nicotine addiction
Nicotine and cigarette/tobacco use continue to be a prevalent public health issue worldwide. The transition to nicotine ad...
ASIC1a channels in the locus coeruleus mediate hypercapnic acidosis detection and CO-induced panic behavior
ASIC1a channels in the locus coeruleus mediate hypercapnic acidosis detection and CO-induced panic behavior
There is a connection between respiratory pathologies and panic disorder, since episodes of hypercapnia can trigger anxiet...
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