Adolphs R (2013) The biology of fear. Curr Biology: CB 23(2):R79–93. https://doi.org/10.1016/j.cub.2012.11.055

Article  CAS  PubMed  Google Scholar 

American Psychiatric Association (2013) Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition). American Psychiatric Association. https://doi.org/10.1176/appi.books.9780890425596

Aschauer DF, Eppler J-B, Ewig L, Chambers AR, Pokorny C, Kaschube M, Rumpel S (2022) Learning-induced biases in the ongoing dynamics of sensory representations predict stimulus generalization. Cell Rep 38(6):110340. https://doi.org/10.1016/j.celrep.2022.110340

Article  CAS  PubMed  Google Scholar 

Asok A, Kandel ER, Rayman JB (2019) The neurobiology of fear generalization. Front Behav Neurosci 12:329. https://doi.org/10.3389/fnbeh.2018.00329

Article  PubMed  PubMed Central  Google Scholar 

Atucha E, Roozendaal B (2015) The inhibitory avoidance discrimination task to investigate accuracy of memory. Front Behav Neurosci 9. https://doi.org/10.3389/fnbeh.2015.00060

Atucha E, Vukojevic V, Fornari RV, Ronzoni G, Demougin P, Peter F, Atsak P, Coolen MW, Papassotiropoulos A, McGaugh JL, De Quervain DJ-F, Roozendaal B (2017) Noradrenergic activation of the basolateral amygdala maintains hippocampus-dependent accuracy of remote memory. Proceedings of the National Academy of Sciences, 114(34), 9176–9181. https://doi.org/10.1073/pnas.1710819114

Bahtiyar S, Gulmez Karaca K, Henckens MJAG, Roozendaal B (2020) Norepinephrine and glucocorticoid effects on the brain mechanisms underlying memory accuracy and generalization. Mol Cell Neurosci 108:103537. https://doi.org/10.1016/j.mcn.2020.103537

Article  CAS  PubMed  Google Scholar 

Baldi E (2004) Footshock intensity and generalization in contextual and auditory-cued fear conditioning in the rat. Neurobiol Learn Mem 81(3):162–166. https://doi.org/10.1016/j.nlm.2004.02.004

Article  PubMed  Google Scholar 

Besnard A, Sahay A (2016) Adult hippocampal neurogenesis, fear generalization, and stress. Neuropsychopharmacology 41(1):24–44. https://doi.org/10.1038/npp.2015.167

Article  PubMed  Google Scholar 

Bloom AS, Quinton EE, Carr LA (1977) Effects of cycloheximide, diethyldithiocarbamate and d-amphetamine on protein and catecholamine biosynthesis in mouse brain. Neuropharmacology 16(6):411–418. https://doi.org/10.1016/0028-3908(77)90082-X

Article  CAS  PubMed  Google Scholar 

Canal CE, Chang Q, Gold PE (2007) Amnesia produced by altered release of neurotransmitters after intraamygdala injections of a protein synthesis inhibitor. Proc Natl Acad Sci USA 104(30):12500–12505. https://doi.org/10.1073/pnas.0705195104

Article  CAS  PubMed  PubMed Central  Google Scholar 

Carr LA, Wehry SM (1980) Effect of cycloheximide and d-amphetamine on brain catecholamines in two mouse strains. Pharmacol Biochem Behav 13(2):193–197. https://doi.org/10.1016/0091-3057(80)90072-6

Article  CAS  PubMed  Google Scholar 

Cooper SE, Van Dis EAM, Hagenaars MA, Krypotos A-M, Nemeroff CB, Lissek S, Engelhard IM, Dunsmoor JE (2022) A meta-analysis of conditioned fear generalization in anxiety-related disorders. Neuropsychopharmacology 47(9):1652–1661. https://doi.org/10.1038/s41386-022-01332-2

Article  PubMed  PubMed Central  Google Scholar 

Dos Santos Corrêa M, Vaz BDS, Grisanti GDV, De Paiva JPQ, Tiba PA, Fornari RV (2019) Relationship between footshock intensity, post-training corticosterone release and contextual fear memory specificity over time. Psychoneuroendocrinology 110:104447. https://doi.org/10.1016/j.psyneuen.2019.104447

Article  CAS  PubMed  Google Scholar 

Dos Santos Corrêa M, Vaz BDS, Menezes BS, Ferreira TL, Tiba PA, Fornari RV (2021) Corticosterone differentially modulates time-dependent fear generalization following mild or moderate fear conditioning training in rats. Neurobiol Learn Mem 184:107487. https://doi.org/10.1016/j.nlm.2021.107487

Article  CAS  PubMed  Google Scholar 

Dunsmoor JE, Kroes MCW, Li J, Daw ND, Simpson HB, Phelps EA (2019) Role of Human Ventromedial Prefrontal Cortex in Learning and Recall of enhanced extinction. J Neuroscience: Official J Soc Neurosci 39(17):3264–3276. https://doi.org/10.1523/JNEUROSCI.2713-18.2019

Article  CAS  Google Scholar 

Dymond S, Dunsmoor JE, Vervliet B, Roche B, Hermans D (2015) Fear generalization in humans: systematic review and implications for anxiety disorder research. Behav Ther 46(5):561–582. https://doi.org/10.1016/j.beth.2014.10.001

Article  PubMed  Google Scholar 

Ehret G (2001) Adaptations in the Mouse Auditory System for Perception of Ultrasonic Communication Calls. J Evol Biochem Physiol 37(5):562–568. https://doi.org/10.1023/A:1014042915818

Article  Google Scholar 

Flood JF, Bennett EL, Rosenzweig MR, Orme AE (1972) Influence of training strength on amnesia induced by pretraining injections of cycloheximide. Physiol Behav 9(4):589–600. https://doi.org/10.1016/0031-9384(72)90017-0

Article  CAS  PubMed  Google Scholar 

Flood JF, Rosenzweig MR, Bennett EL, Orme AE (1973) The influence of duration of protein synthesis inhibition on memory. Physiol Behav 10(3):555–562. https://doi.org/10.1016/0031-9384(73)90221-7

Article  CAS  PubMed  Google Scholar 

Freedman LS, Judge ME, Quartermain D (1982) Effects of cycloheximide, a protein synthesis inhibitor, on mouse brain catecholamine biochemistry. Pharmacol Biochem Behav 17(2):187–191. https://doi.org/10.1016/0091-3057(82)90068-5

Article  CAS  PubMed  Google Scholar 

Garren LD, Ney RL, Davis WW (1965) Studies on the role of protein synthesis in the regulation of corticosterone production by adrenocorticotropic hormone in vivo. Proceedings of the National Academy of Sciences, 53(6), 1443–1450. https://doi.org/10.1073/pnas.53.6.1443

Gazarini L, Stern CAJ, Carobrez AP, Bertoglio LJ (2013) Enhanced noradrenergic activity potentiates fear memory consolidation and reconsolidation by differentially recruiting α1- and β-adrenergic receptors. Learn Memory (Cold Spring Harbor N Y) 20(4):210–219. https://doi.org/10.1101/lm.030007.112

Article  CAS  Google Scholar 

Gazarini L, Stern CA, Takahashi RN, Bertoglio LJ (2022) Interactions of Noradrenergic, glucocorticoid and Endocannabinoid Systems Intensify and generalize fear memory traces. Neuroscience 497:118–133. https://doi.org/10.1016/j.neuroscience.2021.09.012

Article  CAS  PubMed  Google Scholar 

Ghosh S, Chattarji S (2015) Neuronal encoding of the switch from specific to generalized fear. Nat Neurosci 18(1):112–120. https://doi.org/10.1038/nn.3888

Article  CAS  PubMed  Google Scholar 

Gold PE, Wrenn SM (2012) Cycloheximide impairs and enhances memory depending on dose and footshock intensity. Behav Brain Res 233(2):293–297. https://doi.org/10.1016/j.bbr.2012.05.010

Article  CAS  PubMed  PubMed Central  Google Scholar 

Grosso A, Santoni G, Manassero E, Renna A, Sacchetti B (2018) A neuronal basis for fear discrimination in the lateral amygdala. Nat Commun 9(1):1214. https://doi.org/10.1038/s41467-018-03682-2

Article  CAS  PubMed  PubMed Central  Google Scholar 

Han J-H, Yiu AP, Cole CJ, Hsiang H-L, Neve RL, Josselyn SA (2008) Increasing CREB in the auditory thalamus enhances memory and generalization of auditory conditioned fear. Learn Mem 15(6):443–453. https://doi.org/10.1101/lm.993608

Article  PubMed  PubMed Central  Google Scholar 

Hernandez PJ, Abel T (2008) The role of protein synthesis in memory consolidation: Progress amid decades of debate. Neurobiol Learn Mem 89(3):293–311. https://doi.org/10.1016/j.nlm.2007.09.010

Article  CAS  PubMed  Google Scholar 

Iborra-Lázaro G, Djebari S, Sánchez-Rodríguez I, Gratacòs-Batlle E, Sánchez-Fernández N, Radošević M, Casals N, Navarro-López J, de Del Cerro DS, D., Jiménez-Díaz L (2023) CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative and non-associative learning. J Physiol 601(16):3533–3556. https://doi.org/10.1113/JP284248

Article  PubMed  Google Scholar 

Joëls M, Fernandez G, Roozendaal B (2011) Stress and emotional memory: A matter of timing. Trends Cogn Sci 15(6):280–288. https://doi.org/10.1016/j.tics.2011.04.004

Article  PubMed  Google Scholar 

Kausche FM, Zerbes G, Kampermann L, Müller JC, Wiedemann K, Büchel C, Schwabe L (2021) Noradrenergic stimulation increases fear memory expression. Eur Neuropsychopharmacology: J Eur Coll Neuropsychopharmacol 43:71–81. https://doi.org/10.1016/j.euroneuro.2020.1