Post-methamphetamine working memory decline predicts relapse vulnerability in rats and is rescued by mGlu3 receptor activation

Abulseoud OA, Miller JD, Wu J, Choi D-S, Holschneider DP (2012) Ceftriaxone upregulates the glutamate transporter in medial prefrontal cortex and blocks reinstatement of methamphetamine seeking in a condition place preference paradigm. Brain Res 1456:14–21. https://doi.org/10.1016/j.brainres.2012.03.045

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alizadehgoradel J, Nejati V, Sadeghi Movahed F, Imani S, Taherifard M, Mosayebi-Samani M, Vicario CM, Nitsche MA, Salehinejad MA (2020) Repeated stimulation of the dorsolateral-prefrontal cortex improves executive dysfunctions and craving in drug addiction: a randomized, doubleblind, parallel-group study. Brain Stimulat 13:582–593. https://doi.org/10.1016/j.brs.2019.12.028

Article  Google Scholar 

Arnsten AFT, Jin LE (2014) Molecular influences on working memory circuits in dorsolateral prefrontal cortex. Prog Mol Biol Transl Sci 122:211–231. https://doi.org/10.1016/B978-0-12-420170-5.00008-8

Article  CAS  PubMed  Google Scholar 

Arnsten AFT, Wang M (2020) The evolutionary expansion of mGluR3-NAAG-GCPII signaling: relevance to human intelligence and cognitive disorders. Am J Psychiatry 177(12):1103–1106. https://doi.org/10.1176/appi.ajp.2020.20101458

Article  PubMed  Google Scholar 

Auger ML, Floresco SB (2017) Prefrontal cortical GABAergic and NMDA glutamatergic regulation of delayed responding. Neuropharmacology 113(Pt A 10–20. https://doi.org/10.1016/j.neuropharm.2016.09.022

Bishop JR, Reilly JL, Harris MSH, Patel SR, Kittles R, Badner JA, Prasad KM, Nimgaonkar VL, Keshavan MS, Sweeney JA (2015) Pharmacogenetic associations of the type-3 metabotropic glutamate receptor (GRM3) gene with working memory and clinical symptom response to antipsychotics in first-episode schizophrenia. Psychopharmacology 232(1):145–154. https://doi.org/10.1007/s00213-014-3649-4

Article  CAS  PubMed  Google Scholar 

Blaes SL, Orsini CA, Holik HM, Stubbs TD, Ferguson SN, Heshmati SC, Bruner MM, Wall SC, Febo M, Bruijnzeel AW, Bizon JL, Setlow B (2019) Enhancing effects of acute exposure to cannabis smoke on working memory performance. Neurobiol Learn Mem 157:151–162. https://doi.org/10.1016/j.nlm.2018.12.001

Article  CAS  PubMed  Google Scholar 

Caraci F, Molinaro G, Battaglia G, Giuffrida ML, Riozzi B, Traficante A, Bruno V, Cannella M, Merlo S, Wang X, Heinz BA, Nisenbaum ES, Britton TC, Drago F, Sortino MA, Copani A, Nicoletti F (2011) Targeting group II metabotropic glutamate (mGlu) receptors for the treatment of psychosis associated with alzheimer’s disease: selective activation of mGlu2 receptors amplifies beta-amyloid toxicity in cultured neurons, whereas dual activation of mGlu2 and mGlu3 receptors is neuroprotective. Mol Pharmacol 79(3):618–626. https://doi.org/10.1124/mol.110.067488

Article  CAS  PubMed  Google Scholar 

Chen W, Liu B, Li X, Wang P, Wang B (2020) Sex differences in Spatial memory. Neuroscience 443:140–147. https://doi.org/10.1016/j.neuroscience.2020.06.016

Article  CAS  PubMed  Google Scholar 

Chiu H-Y, Chan M-H, Lee M-Y, Chen S-T, Zhan Z-Y, Chen H-H (2014) Long-lasting alterations in 5-HT2A receptor after a binge regimen of methamphetamine in mice. Int J Neuropsychopharmacol 17(10):1647–1658. https://doi.org/10.1017/S1461145714000455

Article  CAS  PubMed  Google Scholar 

Ciacciarelli EJ, Dunn SD, Gohar T, Sloand J, Niedringhaus T, M., West EA (2025) Medial prefrontal cortex to nucleus reuniens circuit is critical for performance in an operant delayed nonmatch to position task. Neurobiol Learn Mem 217:108007. https://doi.org/10.1016/j.nlm.2024.108007

Article  PubMed  Google Scholar 

Daiwile AP, Jayanthi S, Cadet JL (2022) Sex differences in methamphetamine use disorder perused from pre-clinical and clinical studies: potential therapeutic impacts. Neurosci Biobehav Rev 137:104674. https://doi.org/10.1016/j.neubiorev.2022.104674

Article  CAS  PubMed  PubMed Central  Google Scholar 

Datta D, Leslie SN, Woo E, Amancharla N, Elmansy A, Lepe M, Mecca AP, Slusher BS, Nairn AC, Arnsten AFT (2021) Glutamate carboxypeptidase II in aging rat prefrontal cortex impairs working memory performance. Front Aging Neurosci 13:760270. https://doi.org/10.3389/fnagi.2021.760270

Article  CAS  PubMed  PubMed Central  Google Scholar 

de Quervain DJ-F, Papassotiropoulos A (2006) Identification of a genetic cluster influencing memory performance and hippocampal activity in humans. Proc Natl Acad Sci USA 103(11):4270–4274. https://doi.org/10.1073/pnas.0510212103

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dluzen DE, Liu B (2008) Gender differences in methamphetamine use and responses: A review. Gend Med 5(1):24–35. https://doi.org/10.1016/S1550-8579(08)80005-8

Article  PubMed  Google Scholar 

Dogra S, Stansley BJ, Xiang Z, Qian W, Gogliotti RG, Nicoletti F, Lindsley CW, Niswender CM, Joffe ME, Conn PJ (2021) Activating mGlu3 metabotropic glutamate receptors rescues Schizophrenia-like cognitive deficits through metaplastic adaptations within the Hippocampus. Biol Psychiatry 90(6):385–398. https://doi.org/10.1016/j.biopsych.2021.02.970

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ersche KD, Clark L, London M, Robbins TW, Sahakian BJ (2006) Profile of executive and memory function associated with amphetamine and opiate dependence. Neuropsychopharmacol 31:1036–1047. https://doi.org/10.1038/sj.npp.1300889

Article  CAS  PubMed  Google Scholar 

Egan MF, Straub RE, Goldberg TE, Yakub I, Callicott JH, Hariri AR, Mattay VS, Bertolino A, Hyde TM, Shannon-Weickert C, Akil M, Crook J, Vakkalanka RK, Balkissoon R, Gibbs RA, Kleinman JE, Weinberger DR (2004) Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia. Proc Natl Acad Sci USA 101(34):12604–12609. https://doi.org/10.1073/pnas.0405077101

Article  CAS  PubMed  PubMed Central  Google Scholar 

Faul F, Erdfelder E, Lang A-G, Buchner A (2007) G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 39(2):175–191. https://doi.org/10.3758/BF03193146

Article  PubMed  Google Scholar 

Faul F, Erdfelder E, Buchner A, Lang A-G (2009) Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses. Behav Res Methods 41(4):1149–1160. https://doi.org/10.3758/BRM.41.4.1149

Article  PubMed  Google Scholar 

Fultz EK, Nei AYT, Chi JC, Lichter JN, Szumlinski KK (2024) Effects of systemic pretreatment with the NAALADase inhibitor 2-PMPA on oral methamphetamine reinforcement in C57BL/6J mice. Front Psychiatry 15:1297275. https://doi.org/10.3389/fpsyt.2024.1297275

Article  PubMed  PubMed Central  Google Scholar 

Ghose S, Gleason KA, Potts BW, Lewis-Amezcua K, Tamminga CA (2009) Differential expression of metabotropic glutamate receptors 2 and 3 in schizophrenia: a mechanism for antipsychotic drug action? Am J Psychiatry 166(7):812–820. https://doi.org/10.1176/appi.ajp.2009.08091445

Article  PubMed  PubMed Central  Google Scholar 

Gobin C, Schwendt M (2020) The cognitive cost of reducing relapse to cocaine-seeking with mGlu5 allosteric modulators. Psychopharmacology 237(1):115–125. https://doi.org/10.1007/s00213-019-05351-8

Article  CAS  PubMed  Google Scholar 

Gobin C, Wu L, Schwendt M (2020) Using rat operant delayed match-to-sample task to identify neural substrates recruited with increased working memory load. Learn Mem 27(11):467–476. https://doi.org/10.1101/lm.052134.120

Article  CAS  PubMed  PubMed Central  Google Scholar 

Goldman-Rakic PS (1995) Cellular basis of working memory. Neuron 14(3):477–485. https://doi.org/10.1016/0896-6273(95)90304-6

Article  CAS  PubMed  Google Scholar 

Gonzalez R, Bechara A, Martin EM (2007) Executive functions among individuals withmethamphetamine or alcohol as drugs of choice: preliminary observations. J Clin Exp Neuropsychol 29:155–159. https://doi.org/10.1080/13803390600582446

Article  PubMed  Google Scholar 

Hámor PU, Šírová J, Páleníček T, Zaniewska M, Bubeníková-Valešová V, Schwendt M (2018) Chronic methamphetamine self-administration dysregulates 5-HT2A and mGlu2 receptor expression in the rat prefrontal and perirhinal cortex: comparison to chronic phencyclidine and MK-801. Pharmacol Biochem Behav 175:89–100. https://doi.org/10.1016/j.pbb.2018.09.007

Article  CAS  PubMed  PubMed Central 

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