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Cross-species transmission risks in farmed and wild mammals
A study by Shi et al. uncovers uncharted diversity of potential pathogens and mobile antibiotic resistance genes in sample...
Erythrocyte invasion in malaria: from molecular mechanisms to rational vaccines
Erythrocyte invasion in malaria: from molecular mechanisms to rational vaccines
Plasmodium parasites, which cause malaria, invade and remodel our red blood cells, creating niches in which they replicate...
New Cryptosporidium parvum fitness factor
New Cryptosporidium parvum fitness factor
A new study by Huang et al. identifies a Cryptosporidium parvum ABC transporter that confers resistance to a toxic gut mic...
Warming waters, declining Prochlorococcus
This study reports the possible negative effects of warming sea surface temperatures on Prochlorococcus populations.
Biosynthesis and function of magnetic organelles in magnetotactic bacteria
Biosynthesis and function of magnetic organelles in magnetotactic bacteria
One of the most intricate structures found in bacterial cells are magnetosomes of magnetotactic bacteria. These membrane-b...
Zoonotic threats hidden in wildlife
Zoonotic threats hidden in wildlife
This Genome Watch article explores how metagenomics can be used to investigate viral diversity and track emerging zoonotic...
Fusobacterium nucleatum: ecology, pathogenesis and clinical implications
Fusobacterium nucleatum: ecology, pathogenesis and clinical implications
Fusobacterium nucleatum, a commensal microorganism and opportunistic pathogen (a pathobiont), has emerged as a key player ...
Prophage against phage
Prophage against phage
This study reports the identification of two prophage-encoded systems involved in anti-phage defence through Abi.
Opposing forces
Opposing forces
This study shows that metabolites from both an infecting pathogen and the gut microbiota of the host are major determinant...
Microbial interactions lead to ecosystem function
In this Journal Club, Flora Vincent revisits a paper that summarized the ecological roles of microorganisms in the ocean e...
Stopping Marburg virus in its tracks
In this study, Cross, Woolsey, Prasad et al. report obeldesivir as a promising post-exposure prophylaxis for filoviruses.
Bacterial contact killing
This study reports that bacteria protect plants against filamentous fungal infections via intercellular contacts between t...
A kill switch for tuberculosis
A kill switch for tuberculosis
In two recent studies, Smith, Su, Wallach et al. engineered a safer version of Bacille Calmette–Guerin with strong p...
Overcoming research challenges in resource-limited settings: perspectives from Thailand
This Comment highlights the challenges and rewards of researchers working in resource-limited settings, specifically Thail...
Mining microbiomes for microproteins
Mining microbiomes for microproteins
This Genome Watch discusses strategies to detect small open reading frames and study microproteins encoded in microbiomes ...
Fungal biofilms in human health and disease
Fungal biofilms in human health and disease
Increased use of implanted medical devices, use of immunosuppressants and an ageing population have driven the rising freq...
A never-ending defence fight
A never-ending defence fight
Two recent studies provide mechanistic understanding of how bacteria employ the Gabija system for defence against phages, ...
Daughters remember to swarm
The data of the study suggest that bacteria possess a physiological iron memory that persists over multiple generations.
Staphylococcus aureus gets itchy
Staphylococcus aureus gets itchy
This study reports a mechanism whereby a Staphylococcus aureus protease induces itch by activating a host receptor on sens...
The honeybee microbiota and its impact on health and disease
The honeybee microbiota and its impact on health and disease
Honeybees (Apis mellifera) are key pollinators that support global agriculture and are long-established models for develop...
Jumping between hosts
In this study, Lee et al. analyse the structure and receptor-binding features of the spike glycoprotein from a clade 3 sar...
Machine learning sheds light on microbial dark proteins
Machine learning sheds light on microbial dark proteins
This month’s Genome Watch highlights the recent use of machine learning to uncover functional ‘dark matterR...
Antibodies versus P. aeruginosa
In this study, Simonis et al. show that chronic infection with Pseudomonas aeruginosa leads to development of neutralizing...
Keep calm with ammonia-producing microbiota
Keep calm with ammonia-producing microbiota
In this study, Wang et al. show that bacterium-derived intestinal ammonia modulates glutamine production in the mouse brai...
Urban malaria
This study provides evidence for a role of Anopheles stephensi in driving urban malaria outbreaks.
Machine learning for microbiologists
Machine learning for microbiologists
Machine learning is increasingly important in microbiology where it is used for tasks such as predicting antibiotic resist...
Mycobacterial cords
This study reports that intracellular cord formation by Mycobacterium tuberculosis is an important feature of early pathog...
Microbial murmurs — decoding hidden conversations between bacteria
Microbial murmurs — decoding hidden conversations between bacteria
This month’s Genome Watch highlights how a tailor-made search through bacterial genomes revealed the widespread pres...
Sabotage of CRISPR–Cas
Sabotage of CRISPR–Cas
This study reports the identification of an archaeal virus Acr protein that blocks the dissociation of the target RNA from...
Beneficial applications of biofilms
Beneficial applications of biofilms
Many microorganisms live in the form of a biofilm. Although they are feared in the medical sector, biofilms that are compo...
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