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T cell-mediated protection in absence of virus neutralizing antibodies
T cell-mediated protection in absence of virus neutralizing antibodies
Vaccine-induced neutralizing antibodies are widely considered sufficient and required for protection from yellow fever and...
KorB switching from DNA-sliding clamp to repressor mediates long-range gene silencing in a multi-drug resistance plasmid
KorB switching from DNA-sliding clamp to repressor mediates long-range gene silencing in a multi-drug resistance plasmid
Examples of long-range gene regulation in bacteria are rare and generally thought to involve DNA looping. Here, using a co...
Predicting child health with gut microbiome development trajectories
The human gut microbiome plays a vital role in aiding digestion, regulating host immunity, metabolism, protecting against ...
Explainable artificial intelligence evolves antimicrobial peptides
Explainable artificial intelligence evolves antimicrobial peptides
An explainable deep learning model enables the identification and virtual optimization of antimicrobial peptides (AMPs) fr...
A gut microorganism turns the dial on sugar intake
A gut microorganism turns the dial on sugar intake
A Bacteroides vulgatus metabolite, pantothenate, induces secretion of the hormones GLP1 in the gut and FGF21 in the liver,...
Longitudinal phage–bacteria dynamics in the early life gut microbiome
Longitudinal phage–bacteria dynamics in the early life gut microbiome
Microbial colonization of the human gut occurs soon after birth, proceeds through well-studied phases and is affected by l...
Integrons are anti-phage defence libraries in Vibrio parahaemolyticus
Integrons are anti-phage defence libraries in Vibrio parahaemolyticus
Bacterial genomes have regions known as defence islands that encode diverse systems to protect against phage infection. Al...
Close the gender gap in Africa’s HIV epidemic
Close the gender gap in Africa’s HIV epidemic
Improving HIV interventions for men could reduce HIV acquisition in women, close the growing gender gap in HIV infections ...
Bacteroides fragilis ubiquitin homologue drives intraspecies bacterial competition in the gut microbiome
Bacteroides fragilis ubiquitin homologue drives intraspecies bacterial competition in the gut microbiome
Interbacterial antagonism and associated defensive strategies are both essential during bacterial competition. The human g...
BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibility
BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibility
Oxidative stress triggers ferroptosis, a form of cellular necrosis characterized by iron-dependent lipid peroxidation, and...
Placental group B Streptococcus is associated with increased risk of adverse foetal outcome
Placental group B Streptococcus is associated with increased risk of adverse foetal outcome
The placenta nourishes the foetus and supports its development and growth. Our study now identifies the placenta as a pote...
Longitudinal population-level HIV epidemiologic and genomic surveillance highlights growing gender disparity of HIV transmission in Uganda
Longitudinal population-level HIV epidemiologic and genomic surveillance highlights growing gender disparity of HIV transmission in Uganda
HIV incidence in eastern and southern Africa has historically been concentrated among girls and women aged 15–24 yea...
Tackling climate change and deforestation to protect against vector-borne diseases
Tackling climate change and deforestation to protect against vector-borne diseases
The spread of vector-borne infectious diseases is driven by a complex array of environmental and social drivers, including...
Small organisms with big climate impact
Small organisms with big climate impact
To coincide with the 28th United Nations Climate Change Conference (COP28), taking place in Dubai, United Arab Emirates, w...
Global warming could drive the emergence of new fungal pathogens
Global warming could drive the emergence of new fungal pathogens
Increased heat tolerance in fungi with pathogenic potential due to global warming could bring new fungal diseases.
Climate extremes disrupt fungal–bacterial interactions
Climate extremes disrupt fungal–bacterial interactions
Climate changes can destabilize soil microbial communities, but compound and sequential extreme climate events will magnif...
Microbiology must be represented at climate change talks
Microbiology must be represented at climate change talks
But Peixoto found one aspect of the meeting particularly unsettling: in all the climate discussions, microbes were effecti...
Climate change impacts on bird migration and highly pathogenic avian influenza
Climate change impacts on bird migration and highly pathogenic avian influenza
The unprecedented extent of highly pathogenic avian influenza coincides with intensifying global climate changes that alte...
Climate and health strategies must take vaccination into account
Mora, C. et al. Nat. Clim. Change 12, 869–875 (2022).Article  Google Scholar  Fré...
Assessing critical thresholds in terrestrial microbiomes
Assessing critical thresholds in terrestrial microbiomes
Critical thresholds are abrupt changes in ecosystems triggered by environmental disturbances, which can be used to assess ...
Author Correction: Arbuscular mycorrhizal fungi heterokaryons have two nuclear populations with distinct roles in host–plant interactions
Yanina S. Rizzi & Caroline GutjahrPresent address: Max-Planck-Institute of Molecular Plant Physiology, Potsdam-Golm, G...
A geometry-based approach to make viable-cell counting easy and cheap
A geometry-based approach to make viable-cell counting easy and cheap
Counting the number of viable cells in a culture remains a critical measurement in microbiology, but traditional dilution ...
Drug resistance and vaccine target surveillance of Plasmodium falciparum using nanopore sequencing in Ghana
Drug resistance and vaccine target surveillance of Plasmodium falciparum using nanopore sequencing in Ghana
Malaria results in over 600,000 deaths annually, with the highest burden of deaths in young children living in sub-Saharan...
Metabolic exchanges are ubiquitous in natural microbial communities
Metabolic exchanges are ubiquitous in natural microbial communities
Microbial communities drive global biogeochemical cycles and shape the health of plants and animals—including humans...
Multiple micronutrient deficiencies in early life cause multi-kingdom alterations in the gut microbiome and intrinsic antibiotic resistance genes in mice
Multiple micronutrient deficiencies in early life cause multi-kingdom alterations in the gut microbiome and intrinsic antibiotic resistance genes in mice
Globally, ~340 million children suffer from multiple micronutrient deficiencies, accompanied by high pathogenic burden and...
Obligate biotroph downy mildew consistently induces near-identical protective microbiomes in Arabidopsis thaliana
Obligate biotroph downy mildew consistently induces near-identical protective microbiomes in Arabidopsis thaliana
Hyaloperonospora arabidopsidis (Hpa) is an obligately biotrophic downy mildew that is routinely cultured on Arabidopsis th...
Above- and belowground fungal biodiversity of Populus trees on a continental scale
Above- and belowground fungal biodiversity of Populus trees on a continental scale
Understanding drivers of terrestrial fungal communities over large scales is an important challenge for predicting the fat...
Systematic mining of the human microbiome identifies antimicrobial peptides with diverse activity spectra
Systematic mining of the human microbiome identifies antimicrobial peptides with diverse activity spectra
Human-associated bacteria secrete modified peptides to control host physiology and remodel the microbiota species composit...
Simultaneous spatiotemporal transcriptomics and microscopy of Bacillus subtilis swarm development reveal cooperation across generations
Simultaneous spatiotemporal transcriptomics and microscopy of Bacillus subtilis swarm development reveal cooperation across generations
Development of microbial communities is a complex multiscale phenomenon with wide-ranging biomedical and ecological implic...
The Isala project’s empowered new insights into the vaginal microbiome and women’s health
The Isala project’s empowered new insights into the vaginal microbiome and women’s health
Empowering women through citizen science, from using self-collected vaginal samples to participant input on research quest...
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