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The Ecology of Pathogenic Onygenales Fungi and the Impacts of Climate Change
The Ecology of Pathogenic Onygenales Fungi and the Impacts of Climate Change
Onygenalean fungi have the potential to cause disease in vertebrates, including humans, due to their possession of various...
Host-vaginal microbiota interaction: shaping the vaginal microenvironment and bacterial vaginosis
Host-vaginal microbiota interaction: shaping the vaginal microenvironment and bacterial vaginosis
This review comprehensively examines host-vaginal microbiota interactions, the composition of the vaginal microbiota, and ...
SARS-CoV-2 Resistance to Small Molecule Inhibitors
SARS-CoV-2 Resistance to Small Molecule Inhibitors
SARS-CoV-2 undergoes genetic mutations like many other viruses. Some mutations lead to the emergence of new Variants of Co...
Update on the Regulation and Maintenance of Epstein-Barr Virus Latency
Update on the Regulation and Maintenance of Epstein-Barr Virus Latency
As the first identified human oncogenic virus, Epstein-Barr virus (EBV) is widely circulating in humans. EBV presents main...
Foodborne Helminthiasis
Foodborne Helminthiasis
This review focuses on key foodborne helminths: providing an overview of their lifecycles and major transmission routes to...
Modulation of Wnt Signaling Pathway during Cytomegalovirus Latency and Reactivation
Modulation of Wnt Signaling Pathway during Cytomegalovirus Latency and Reactivation
The Wnt signaling pathway is one of the key pathways involved in hematopoietic progenitor cell (HPC) proliferation and dif...
Resistance Mechanisms to Amphotericin B Alternative Treatments Development
Resistance Mechanisms to Amphotericin B Alternative Treatments Development
Systemic fungal infections caused by Candida auris have been identified since 2009, with mortality rates and drug resistan...
Myeloid Cell Reservoirs: Role in HIV-Host Interplay and Strategies for Myeloid Reservoir Elimination
Myeloid Cell Reservoirs: Role in HIV-Host Interplay and Strategies for Myeloid Reservoir Elimination
Despite host antiviral responses and antiretroviral therapy, HIV-1 continues to persist in myeloid cell reservoirs. Hence,...
Virulence Traits in Commensalism and Disease
Virulence Traits in Commensalism and Disease
Candida albicans is a common constituent of the normal human microbiota of the oro-gastrointestinal and vaginal tract. The...
Integrating Genomic Data with the Development of CRISPR-Based Point-of-Care-Testing for Bacterial Infections
Integrating Genomic Data with the Development of CRISPR-Based Point-of-Care-Testing for Bacterial Infections
Bacterial infections and antibiotic resistance contribute to global mortality. Despite many infections being preventable a...
Molecular Insights Into the Interplay Between Host Platelets and Fungal Pathogens
Molecular Insights Into the Interplay Between Host Platelets and Fungal Pathogens
Despite the rise in invasive fungal infections, little is understood about these illnesses, especially the relationship be...
Agent-Based Models of Virus Infection
Agent-Based Models of Virus Infection
Agent-based modelling (ABM) is a robust computational tool for investigating the dynamics of infectious disease spread and...
Potential Influence of Antifungal-drug Resistant Pathogens in Patients with Cholangiocarcinoma and the Application of Nanoparticle Mechanisms as Novel Antifungal and Anticancer Agents
Potential Influence of Antifungal-drug Resistant Pathogens in Patients with Cholangiocarcinoma and the Application of Nanoparticle Mechanisms as Novel Antifungal and Anticancer Agents
Cholangiocarcinoma (CCA) is the most lethal and common malignant tumours that occur in the bile ducts. Although it is rela...
Machine Learning-based Host–Pathogen Protein–Protein Interaction Prediction
Machine Learning-based Host–Pathogen Protein–Protein Interaction Prediction
This review examines machine learning methods for host–pathogen protein–protein interaction (PPI) prediction. ...
Highly Dynamic Cytoskeletal Networks Support Productive Viral Infection and Host Innate Immune Response Activation
Highly Dynamic Cytoskeletal Networks Support Productive Viral Infection and Host Innate Immune Response Activation
Increasing evidence shows that the onset of the host cytoskeleton changes during the viral infection process. The attainme...
Emerging Roles of Modern Lifestyle Factors in Microbiome Stability and Functionality
Emerging Roles of Modern Lifestyle Factors in Microbiome Stability and Functionality
It is now evident that the microorganisms living on and inside the human body modulate a myriad of host responses and acti...
Human Microbiome and Bacteriophages: Impacts on Health and Disease
Human Microbiome and Bacteriophages: Impacts on Health and Disease
This review explores the direct and indirect interactions between bacteriophages and the human microbiome, aiming to clari...
Bridging Ecology and Microbiomes: Applying Ecological Theories in Host-associated Microbial Ecosystems
Bridging Ecology and Microbiomes: Applying Ecological Theories in Host-associated Microbial Ecosystems
This review explores the application of classical ecological theory to host-associated microbiomes during initial coloniza...
Porin-Mediated Carbapenem Resistance in Klebsiella pneumoniae: an Alarming Threat to Global Health
Porin-Mediated Carbapenem Resistance in Klebsiella pneumoniae: an Alarming Threat to Global Health
Carbapenem resistance among Gram-negative bacteria is becoming a global threat to community health and elevates the antibi...
Status of Drug Discovery in Wetlands Through a Lens of Bioprospecting for New Antimicrobials Being Produced by Microorganisms
Status of Drug Discovery in Wetlands Through a Lens of Bioprospecting for New Antimicrobials Being Produced by Microorganisms
The current review focuses on opportunities for new areas and new methods to isolate microorganisms from soil that could l...
Engineered Therapeutic Antibody Against SARS-CoV-2
Engineered Therapeutic Antibody Against SARS-CoV-2
The success and failure of therapeutic antibodies against SARS-CoV-2 offer a lesson on therapeutic antibody design and dev...
Bacterial and Fungal Keratitis: Current Trends in Its Diagnosis and Management
Bacterial and Fungal Keratitis: Current Trends in Its Diagnosis and Management
Infectious keratitis is the fifth most prevalent cause of blindness worldwide. The primary diagnostic test to identify the...
Molecular Mechanisms of HIV-1 Latency from a Chromatin and Epigenetic Perspective
Molecular Mechanisms of HIV-1 Latency from a Chromatin and Epigenetic Perspective
The main obstacle to an HIV-1 cure is the reservoir of HIV-1 infected cells. While antiretroviral therapy (ART) eliminates...
Gut Microbiota Resilience Mechanisms Against Pathogen Infection and its Role in Inflammatory Bowel Disease
Gut Microbiota Resilience Mechanisms Against Pathogen Infection and its Role in Inflammatory Bowel Disease
Although extensive research has been conducted on microbial resilience, numerous unanswered questions persist. In this stu...
Insight into the Physiological and Molecular Crosstalk During Bacterial-Fungal Interactions
Insight into the Physiological and Molecular Crosstalk During Bacterial-Fungal Interactions
Bacterial-fungal interaction (BFI) is a complex biological crosstalk that influences the ecological processes in the field...
Symbiotic Interactions of Archaea in Animal and Human Microbiomes
Symbiotic Interactions of Archaea in Animal and Human Microbiomes
Since the introduction of Archaea as a new domain of life more than 45 years ago, progress in their phylogenetic classific...
The Application Potential of Synthetic Biology in Microbial Communication
The Application Potential of Synthetic Biology in Microbial Communication
Quorum sensing (QS) signals are very important in microbial communication. In recent years, some new technologies, such as...
Molecular Mechanisms of Severe Diseases Caused by Epstein-Barr Virus Infection
Molecular Mechanisms of Severe Diseases Caused by Epstein-Barr Virus Infection
Epstein-Barr virus (EBV) is a ubiquitous virus that infects > 90% of individuals. EBV has been linked t...
Contagion Went Viral: Microbiology, Entertainment Media and the Public Understanding of Science
Contagion Went Viral: Microbiology, Entertainment Media and the Public Understanding of Science
How has the COVID-19 pandemic influenced how movies are used in public health crises? What made Contagion (2011) the key e...
Conserved and Divergent Features of pH Sensing in Major Fungal Pathogens
Conserved and Divergent Features of pH Sensing in Major Fungal Pathogens
For human fungal pathogens, sensory perception of extracellular pH is essential for colonisation of mammalian tissues and ...
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