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Optimum blue light exposure: a means to increase cell-specific productivity in Chinese hamster ovary cells
Optimum blue light exposure: a means to increase cell-specific productivity in Chinese hamster ovary cells
Research for biopharmaceutical production processes with mammalian cells steadily aims to enhance the cell-specific produc...
Coelimycin inside out — negative feedback regulation by its intracellular precursors
Coelimycin inside out — negative feedback regulation by its intracellular precursors
Coelimycin (CPK) producer Streptomyces coelicolor A3(2) is a well-established model for the genetic studies of bacteria fr...
Unforeseen current and future benefits of uncommon yeast: the Metschnikowia genus
Unforeseen current and future benefits of uncommon yeast: the Metschnikowia genus
Metschnikowia, the single-cell yeast form, is a genus of 85 species in the Saccharomycetales order that developed in both ...
Metabolic mechanism of lignin-derived aromatics in white-rot fungi
Metabolic mechanism of lignin-derived aromatics in white-rot fungi
White-rot fungi, such as Phanerochaete chrysosporium, play a crucial role in biodegrading lignocellulosic biomass includin...
Oral microbiota in preschoolers with rampant caries: a matched case–control study
Oral microbiota in preschoolers with rampant caries: a matched case–control study
Rampant caries is identified by rapid onset, severe decay affecting multiple surfaces, and early pulp infection. This case...
Quantitative fluorescent detection of tetracycline in animal-derived foods using quantum dots
Quantitative fluorescent detection of tetracycline in animal-derived foods using quantum dots
Tetracycline (Tc) antibiotics, a class of synthetically produced broad-spectrum antimicrobial drugs, have been widely used...
Improved recombinant expression of soluble cathepsin B and L in Escherichia coli
Improved recombinant expression of soluble cathepsin B and L in Escherichia coli
Cysteine cathepsins such as cathepsin B and L play an important role in numerous diseases like acute pancreatitis or SARS-...
TssL2 of T6SS2 is required for mobility, biofilm formation, wrinkly phenotype formation, and virulence of Vibrio parahaemolyticus SH112
TssL2 of T6SS2 is required for mobility, biofilm formation, wrinkly phenotype formation, and virulence of Vibrio parahaemolyticus SH112
Type VI secretion system 2 (T6SS2) of Vibrio parahaemolyticus is required for cell adhesion and autophagy in macrophages; ...
Integration of metabolomics and other omics: from microbes to microbiome
Integration of metabolomics and other omics: from microbes to microbiome
Metabolomics is a cutting-edge omics technology that identifies metabolites in organisms and their environments and tracks...
Genomic characteristics and genetic manipulation of the marine yeast Scheffersomyces spartinae
Genomic characteristics and genetic manipulation of the marine yeast Scheffersomyces spartinae
The halotolerant yeast Scheffersomyces spartinae, commonly found in marine environments, holds significant potential for v...
Understanding microbial syngas fermentation rates
Understanding microbial syngas fermentation rates
Syngas fermentation to ethanol has reached industrial production. Further improvement of this process would be aided by qu...
Phormidium versicolor PC skin cream evaluation for its stability and biological activities
Phormidium versicolor PC skin cream evaluation for its stability and biological activities
In the present investigation, 13% ± 0.84 of the extracted and purified phycocyanin from Phormidium versic...
Production of virus-like particles of FMDV by 3C protease cleaving precursor polyprotein P1 in vitro
Production of virus-like particles of FMDV by 3C protease cleaving precursor polyprotein P1 in vitro
Nonstructural protein 3C, a master protease of Picornaviridae, plays a critical role in viral replication by directly clea...
Substrate expansion of Geotrichum candidum alcohol dehydrogenase towards diaryl ketones by mutation
Substrate expansion of Geotrichum candidum alcohol dehydrogenase towards diaryl ketones by mutation
Chiral diaryl alcohols, such as (4-chlorophenyl)(pyridin-2-yl)methanol, are important intermediates for pharmaceutical syn...
Novel isothermal nucleic acid amplification method for detecting malaria parasites
Novel isothermal nucleic acid amplification method for detecting malaria parasites
Malaria, a parasitic disease caused by Plasmodium spp. and transmitted by Anopheles mosquitoes, remains a major global hea...
Maize drought protection by Azospirillum argentinense Az19 requires bacterial trehalose accumulation
Maize drought protection by Azospirillum argentinense Az19 requires bacterial trehalose accumulation
Azospirillum argentinense Az19 is an osmotolerant plant growth-promoting bacterium that protects maize plants from drought...
Holistic monitoring of Campylobacter jejuni biofilms with NanoLuc bioluminescence
Holistic monitoring of Campylobacter jejuni biofilms with NanoLuc bioluminescence
Campylobacter jejuni, a major cause of foodborne zoonotic infections worldwide, shows a paradoxical ability to survive des...
Omics-driven onboarding of the carotenoid producing red yeast Xanthophyllomyces dendrorhous CBS 6938
Omics-driven onboarding of the carotenoid producing red yeast Xanthophyllomyces dendrorhous CBS 6938
Transcriptomics is a powerful approach for functional genomics and systems biology, yet it can also be used for genetic pa...
Multifactorial interaction of selenium, iron, xylose, and glycine on cordycepin metabolism in Cordyceps militaris
Multifactorial interaction of selenium, iron, xylose, and glycine on cordycepin metabolism in Cordyceps militaris
Cordycepin, a nucleoside analog, is the main antioxidative and antimicrobial substance in Cordyceps militaris. To&nbsp...
Chemical and biological evaluation of biosurfactant fractions from Wickerhamomyces anomalus CCMA 0358
Chemical and biological evaluation of biosurfactant fractions from Wickerhamomyces anomalus CCMA 0358
Biosurfactants (BS) are becoming a solution for today’s world since they are considered a reasonable and eco-friendl...
Detection of insecticides by Tetronarce californica acetylcholinesterase via expression and in silico analysis
Detection of insecticides by Tetronarce californica acetylcholinesterase via expression and in silico analysis
The acetylcholinesterase (AChE) is involved in termination of synaptic transmission at cholinergic synapses and plays a vi...
The assembly of gut microbiota implicates shrimp acute hepatopancreas necrosis disease progression
The assembly of gut microbiota implicates shrimp acute hepatopancreas necrosis disease progression
Ample evidence shows dysbiosis in the gut microbiota when comparing healthy shrimp with those affected by severe acute hep...
Identification of a plastic-degrading enzyme from Cryptococcus nemorosus and its use in self-degradable plastics
Identification of a plastic-degrading enzyme from Cryptococcus nemorosus and its use in self-degradable plastics
For decades, plastic waste management has been one of the major ecological challenges of our society. Despite the introduc...
(R/S)-lactate/2-hydroxybutyrate dehydrogenases in and biosynthesis of block copolyesters by Ralstonia eutropha
(R/S)-lactate/2-hydroxybutyrate dehydrogenases in and biosynthesis of block copolyesters by Ralstonia eutropha
Bacterial polyhydroxyalkanoates (PHAs) are promising bio-based biodegradable polyesters. It was recently reported that nov...
The catalytic mechanism of direction-dependent interactions for 2,3-dihydroxybenzoate decarboxylase
The catalytic mechanism of direction-dependent interactions for 2,3-dihydroxybenzoate decarboxylase
Benzoic acid decarboxylases offer an elegant alternative to CO2 fixation by reverse reaction-carboxylation, which is named...
High-cell-density cultivation of Vibrio natriegens in a low-chloride chemically defined medium
High-cell-density cultivation of Vibrio natriegens in a low-chloride chemically defined medium
Vibrio natriegens is a halophilic bacterium with the fastest generation time of non-pathogenic bacteria reported so far. I...
Computational redesign of taxane-10β-hydroxylase for de novo biosynthesis of a key paclitaxel intermediate
Computational redesign of taxane-10β-hydroxylase for de novo biosynthesis of a key paclitaxel intermediate
Paclitaxel (Taxol®) is the most popular anticancer diterpenoid predominantly present in Taxus. The core skeleton of p...
Design and validation of a dual-fluorescence reporter system to monitor bacterial gene expression in the gut environment
Design and validation of a dual-fluorescence reporter system to monitor bacterial gene expression in the gut environment
Fluorescence-based reporter systems are valuable tools for studying gene expression dynamics in living cells. However, ava...
Nile red-based lipid fluorometry protocol and its use for statistical optimization of lipids in oleaginous yeasts
Nile red-based lipid fluorometry protocol and its use for statistical optimization of lipids in oleaginous yeasts
As lipogenic yeasts are becoming increasingly harnessed as biofactories of oleochemicals, the availability of efficient pr...
Elimination of editing plasmid mediated by theophylline riboswitch in Zymomonas mobilis
Elimination of editing plasmid mediated by theophylline riboswitch in Zymomonas mobilis
Zymomonas mobilis is regarded as a potential chassis for the production of platform chemicals. Genome editing using the CR...
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