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Ubiquitin-like modifier-activating enzyme 1 interacts with Zika virus NS5 and promotes viral replication in the infected cell
Ubiquitin-like modifier-activating enzyme 1 interacts with Zika virus NS5 and promotes viral replication in the infected cell
Translation errors, impaired folding or environmental stressors (e.g. infection) can all lead to an increase in the presen...
An improved reverse genetics system for rotavirus vaccine strain LLR using five plasmid vectors
An improved reverse genetics system for rotavirus vaccine strain LLR using five plasmid vectors
Species A rotaviruses (RVs), which belong to the family Sedoreoviridae and contain a genome of 11 segmented dsRNA segments...
A yeast-assembled, plasmid-launched reverse genetics system for the murine coronavirus MHV-A59
A yeast-assembled, plasmid-launched reverse genetics system for the murine coronavirus MHV-A59
The Betacoronavirus murine hepatitis virus (MHV) is an important model system for studying coronavirus (CoV) molecular and...
Unveiling the ghost: machine learning’s impact on the landscape of virology
Unveiling the ghost: machine learning’s impact on the landscape of virology
The complexity and speed of evolution in viruses with RNA genomes makes predictive identification of variants with epidemi...
Transcriptional dynamics during Heliothis zea nudivirus 1 infection in an ovarian cell line from Helicoverpa zea
Transcriptional dynamics during Heliothis zea nudivirus 1 infection in an ovarian cell line from Helicoverpa zea
Nudiviruses (family Nudiviridae) are double-stranded DNA viruses that infect various insects and crustaceans. Among them, ...
Linking the function of cis-acting RNA elements to coronavirus replication using interactomes
Linking the function of cis-acting RNA elements to coronavirus replication using interactomes
RNA structures that are functionally important are defined as cis-acting RNA elements because their functions cannot be co...
ICTV Virus Taxonomy Profile: Bromoviridae 2025
ICTV Virus Taxonomy Profile: Bromoviridae 2025
Bromoviridae is a family of plant viruses with tripartite, positive-sense RNA genomes of about 8 kb in total. Genomic RNAs...
Comparative syncytia formation dynamics of coronavirus MHV-A59 and pneumovirus hRSV A2 and incorporation into improved kinetic virus replication models
Comparative syncytia formation dynamics of coronavirus MHV-A59 and pneumovirus hRSV A2 and incorporation into improved kinetic virus replication models
Replication models have been developed to describe the replication dynamics of a variety of viruses to better understand t...
Utility of hypervariable region in hepatitis E virus for genetic evolution analysis and epidemiological studies
Utility of hypervariable region in hepatitis E virus for genetic evolution analysis and epidemiological studies
Clinical and experimental studies have advanced our understanding of hepatitis E virus (HEV) infection; however, translati...
Genomic analysis reveals low genetic diversity and no continuous reintroduction of piscine myocarditis virus in farmed Atlantic salmon in the Faroe Islands
Genomic analysis reveals low genetic diversity and no continuous reintroduction of piscine myocarditis virus in farmed Atlantic salmon in the Faroe Islands
Piscine myocarditis virus (PMCV) is the causative agent of cardiomyopathy syndrome (CMS), a significant disease in farmed ...
Targeting pseudoknots with Cas13b inhibits porcine epidemic diarrhoea virus replication
Targeting pseudoknots with Cas13b inhibits porcine epidemic diarrhoea virus replication
Clustered regularly interspaced short palindromic repeats-associated protein 13 (CRISPR-Cas13), an RNA editing technology,...
Examining the feasibility of replacing ORF3a with fluorescent genes to construct SARS-CoV-2 reporter viruses
Examining the feasibility of replacing ORF3a with fluorescent genes to construct SARS-CoV-2 reporter viruses
The SARS-CoV-2 genome encodes at least nine accessory proteins, including innate immune antagonist and putative viroporin ...
Prohibitin of swine antagonizes SADS-CoV replication and virus-induced apoptosis
Prohibitin of swine antagonizes SADS-CoV replication and virus-induced apoptosis
Swine acute diarrhoea syndrome coronavirus (SADS-CoV) is an enveloped, single-stranded positive-sense RNA virus that cause...
Erratum: Out-of-sync evolutionary patterns and mutual interplay of major and minor capsid proteins in norovirus GII.2
Erratum: Out-of-sync evolutionary patterns and mutual interplay of major and minor capsid proteins in norovirus GII.2
Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit pu...
The EMCV protein 2B* is required for efficient cell lysis via both caspase-3-dependent and -independent pathways during infection
The EMCV protein 2B* is required for efficient cell lysis via both caspase-3-dependent and -independent pathways during infection
2B* is a poorly characterized protein encoded by an overlapping ORF in the genome of encephalomyocarditis virus (EMCV). We...
Characterisation of the virome of Culicoides brevitarsis Kieffer (Diptera: Ceratopogonidae), a vector of bluetongue virus in Australia
Characterisation of the virome of Culicoides brevitarsis Kieffer (Diptera: Ceratopogonidae), a vector of bluetongue virus in Australia
Culicoides spp., a common biting midge genus, are haematophagous insects that can transmit pathogens to humans and other a...
The loss of both pUL16 and pUL21 in HSV-1-infected cells alters capsid–tegument composition, nuclear membrane architecture, cytoplasmic maturation and cell-to-cell spread
The loss of both pUL16 and pUL21 in HSV-1-infected cells alters capsid–tegument composition, nuclear membrane architecture, cytoplasmic maturation and cell-to-cell spread
Previously, we had developed synthetic genomics methods to assemble an infectious clone of herpes simplex virus type-1 (HS...
Dynamic regulation of autophagy during Semliki Forest virus infection of neuroblastoma cells
Dynamic regulation of autophagy during Semliki Forest virus infection of neuroblastoma cells
Autophagy can defend against infection by delivering viruses to lysosomes for degradation. Semliki Forest virus (SFV) is a...
Genetic characterization of rotavirus A strains circulating in children under 5 years of age with acute gastroenteritis in Tehran, Iran, in 2023–2024: dissemination of the emerging equine-like G3P[8]-I2-E2 DS-1-like strains
Genetic characterization of rotavirus A strains circulating in children under 5 years of age with acute gastroenteritis in Tehran, Iran, in 2023–2024: dissemination of the emerging equine-like G3P[8]-I2-E2 DS-1-like strains
The present study was conducted to monitor the genotype diversity of circulating species A rotavirus (RVA) in Iran. A tota...
Bacilladnaviridae: refined taxonomy and new insights into the biology and evolution of diatom-infecting DNA viruses
Bacilladnaviridae: refined taxonomy and new insights into the biology and evolution of diatom-infecting DNA viruses
Bacilladnaviruses are single-stranded DNA viruses that infect diatoms that, so far, have been primarily identified in mari...
Inhibition of human cytomegalovirus replication by interferon alpha can involve multiple anti-viral factors
Inhibition of human cytomegalovirus replication by interferon alpha can involve multiple anti-viral factors
The shortcomings of current direct-acting anti-viral therapy against human cytomegalovirus (HCMV) has led to interest in h...
ICTV Virus Taxonomy Profile: Leishbuviridae 2023
ICTV Virus Taxonomy Profile: Leishbuviridae 2023
Leishbuviridae is a family of negative-sense RNA viruses with genomes of about 8.0 kb that have been found in protists. Th...
Internalization of rabies virus glycoprotein differs between pathogenic and attenuated virus strains
Internalization of rabies virus glycoprotein differs between pathogenic and attenuated virus strains
The zoonotic rabies virus (RABV) is a non-segmented negative-sense RNA virus classified within the family Rhabdoviridae, a...
Lack of detection of SARS-CoV-2 in British wildlife 2020–21 and first description of a stoat (Mustela erminea) Minacovirus
Lack of detection of SARS-CoV-2 in British wildlife 2020–21 and first description of a stoat (Mustela erminea) Minacovirus
Repeat spillover of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into new hosts has highlighted the critic...
ICTV Virus Taxonomy Profile: Discoviridae 2023
ICTV Virus Taxonomy Profile: Discoviridae 2023
Discoviridae is a family of negative-sense RNA viruses with genomes of 6.2–9.7 kb that have been associated with fungi and...
A novel tamanavirus (Flaviviridae) of the European common frog (Rana temporaria) from the UK
A novel tamanavirus (Flaviviridae) of the European common frog (Rana temporaria) from the UK
Flavivirids are small, enveloped, positive-sense RNA viruses from the family Flaviviridae with genomes of ~9–13 kb. Metatr...
Molecular and biological characterization of a partitivirus from Paecilomyces variotii
Molecular and biological characterization of a partitivirus from Paecilomyces variotii
Paeciliomyces variotii is a thermo-tolerant, ubiquitous fungus commonly found in food products, indoor environments, soil ...
Actin cytoskeleton remodeling disrupts physical barriers to infection and presents entry receptors to respiratory syncytial virus
Actin cytoskeleton remodeling disrupts physical barriers to infection and presents entry receptors to respiratory syncytial virus
RSV is the leading cause of infant hospitalizations and a significant cause of paediatric and geriatric morbidity worldwid...
ICTV Virus Taxonomy Profile: Aoguangviridae 2023
ICTV Virus Taxonomy Profile: Aoguangviridae 2023
The family Aoguangviridae includes dsDNA viruses that have been associated with marine archaea. Currently, members of this...
Establishment of pseudorabies virus latency and reactivation model in mice dorsal root ganglia culture
Establishment of pseudorabies virus latency and reactivation model in mice dorsal root ganglia culture
Pseudorabies virus (PRV) belongs to the alpha herpesvirus family and is responsible for Aujeszky’s disease in pigs. Simila...
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