Adjali A, Clarot I, Chen Z, Marchioni E, Boudier A (2022) Physicochemical degradation of phycocyanin and means to improve its stability: a short review. J Pharm Anal 12:406–414. https://doi.org/10.1016/j.jpha.2021.12.005

Article  PubMed  Google Scholar 

Amberg N, Fogarassy C (2019) Green consumer behavior in the cosmetics market. Resources 8:1–19. https://doi.org/10.3390/resources8030137

Article  Google Scholar 

Amorim ML, Soares J, Coimbra JS dos R, Leite M de O, Albino LFT, Martins MA (2021) Microalgae proteins: production, separation, isolation, quantification, and application in food and feed. Crit. Rev. Food Sci. Nutr 61:1976–2002. https://doi.org/10.1080/10408398.2020.1768046

Anandjiwala S, Bagul MS, Parabia M, Rajani M (2008) Evaluation of free radical scavenging activity of an ayurvedic formulation, Panchvalkala. Indian J Pharm Sci 70:31–35. https://doi.org/10.4103/0250-474X.40328

Article  PubMed  PubMed Central  Google Scholar 

Antelo FS, Costa JAV, Kalil SJ (2008) Thermal degradation kinetics of the phycocyanin from Spirulina platensis. Biochem Eng J 41:43. https://doi.org/10.1016/j.bej.2008.03.012

Article  CAS  Google Scholar 

Arief VO, Trilestari K, Sunarso J, Indraswati N, Ismadji S (2008) Recent progress on biosorption of heavy metals from liquids using low cost biosorbents: characterization, biosorption parameters and mechanism studies. CLEAN – Soil. Air, Water 36:937–962. https://doi.org/10.1002/clen.200800167

Article  CAS  Google Scholar 

Arshad A, Khan HM shoaib, Naveed A (2015) Fabrication, preliminary stability evaluation and in-vitro characterization of polysiloxane polyalkyl polyether copolymer-based cosmetic emulsion. Lat. Am. J. Pharm 34:1797–1807

Arul S, Muthulakshmi M, Sudha M, Gopal S (2012) Extraction, partial purification and antibacterial activity of phycocyanin from Spirulina isolated from fresh water body against various human pathogens. J Algal Biomass Util 3:7–11

Google Scholar 

Aussant J, Guihéneuf F, Stengel DB (2018) Impact of temperature on fatty acid composition and nutritional value in eight species of microalgae. Appl Microbiol Biotechnol 102:5279–5297. https://doi.org/10.1007/s00253-018-9001-x

Article  PubMed  CAS  Google Scholar 

Badruddoza AZM, Yeoh T, Shah JC, Walsh T (2023) Assessing and predicting physical stability of emulsion-based topical semisolid products: a review. J Pharm Sci 112:1772–1793. https://doi.org/10.1016/j.xphs.2023.03.014

Article  PubMed  CAS  Google Scholar 

Balboa E, Conde E, Constenla A, Falqué E, Domínguez H (2017) Sensory evaluation and oxidative stability of a suncream formulated with thermal spring waters from ourense (NW Spain) and Sargassum muticum Extracts. Cosmetics 4:19. https://doi.org/10.3390/cosmetics4020019

Article  CAS  Google Scholar 

Belhaj D, Frikha D, Athmouni K, Jerbi B, Ahmed MB, Bouallagui Z, Kallel M, Maalej S, Zhou J, Ayadi H (2017) Box-Behnken design for extraction optimization of crude polysaccharides from Tunisian Phormidium versicolor cyanobacteria (NCC 466): Partial characterization, in vitro antioxidant and antimicrobial activities. Int J Biol Macromol 105:1501–1510. https://doi.org/10.1016/j.ijbiomac.2017.06.046

Article  PubMed  CAS  Google Scholar 

Benedetti S, Benvenuti F, Scoglio S, Canestrari F (2010) Oxygen radical absorbance capacity of phycocyanin and phycocyanobilin from the food supplement Aphanizomenon flos-aquae. J Med Food 13:223–227. https://doi.org/10.1089/jmf.2008.0257

Article  PubMed  CAS  Google Scholar 

Bennett A, Bogorad L (1973) Complementary chromatic adaptation in a filamentous blue-green alga. J Cell Biol 58:419–435. https://doi.org/10.1083/jcb.58.2.419

Article  PubMed  PubMed Central  CAS  Google Scholar 

Benzie IF, Szeto YT (1999) Total antioxidant capacity of teas by the ferric reducing/antioxidant power assay. J Agric Food Chem 47:633–636. https://doi.org/10.1021/jf9807768

Article  PubMed  CAS  Google Scholar 

Bhat VB, Madyastha KM (2000) C-phycocyanin: a potent peroxyl radical scavenger in vivo and in vitro. Biochem Biophys Res Commun 275:20–25. https://doi.org/10.1006/bbrc.2000.3270

Article  PubMed  CAS  Google Scholar 

Bougatef H, Hadrich F, Gazbar M, Sila A, Chamkha M, Bougatef A (2024) Development of a novel method for the extraction of phycocyanin pigment from Spirulina platensis and assessment of its antioxidant, antimicrobial, and anticancer activities. Biomass Convers Bioref. https://doi.org/10.1007/s13399-024-05540-2

Article  Google Scholar 

Bouyahya A, Bakrim S, Chamkhi I, Taha D, El Omari N, El Mneyiy N, El Hachlafi N, El-Shazly M, Khalid A, Abdalla AN, Goh KW, Ming LC, Goh BH, Aanniz T (2024) Bioactive substances of cyanobacteria and microalgae: sources, metabolism, and anticancer mechanism insights. Biomed Pharmacoth 170:115989. https://doi.org/10.1016/j.biopha.2023.115989

Article  CAS  Google Scholar 

Cardozo KHM, Guaratini T, Barros MP, Falcão VR, Tonon AP, Lopes NP, Campos S, Torres MA, Souza AO, Colepicolo P, Pinto E (2007) Metabolites from algae with economical impact. Comp Biochem Physiol C Toxicol Pharmacol 146:60–78. https://doi.org/10.1016/j.cbpc.2006.05.007

Article  PubMed  CAS  Google Scholar 

Çelekli A, Yavuzatmaca M, Bozkurt H (2009) Kinetic and equilibrium studies on the adsorption of reactive red 120 from aqueous solution on Spirogyra majuscula. J Chem Eng 152:139. https://doi.org/10.1016/j.cej.2009.04.016

Article  CAS  Google Scholar 

Cheng YS, Lam KW, Ng KM, Ko RKM, Wibowo C (2009) An integrative approach to product development-a skin-care cream. Comput Chem Eng 33:1097–1113. https://doi.org/10.1016/j.compchemeng.2008.10.010

Article  PubMed  CAS  Google Scholar 

Dammak M, Ben Hlima H, Smaoui S, Fendri I, Michaud P, Ayadi MA, Abdelkafi S (2022) Conception of an environmental friendly O/W cosmetic emulsion from microalgae. Environ Sci Pollut Res Int 29:73896–73909. https://doi.org/10.1007/s11356-022-20824-8

Article  PubMed  CAS  Google Scholar 

Dejsungkranont M, Chen H-H, Sirisansaneeyakul S (2017) Enhancement of antioxidant activity of C-phycocyanin of Spirulina powder treated with supercritical fluid carbon dioxide. Agri Nat Res 51:347–354. https://doi.org/10.1016/j.anres.2017.12.001

Article  Google Scholar 

Dini I, Laneri S (2021) The new challenge of green cosmetics: natural food ingredients for cosmetic formulations. Molecules 26:3921. https://doi.org/10.3390/molecules26133921

Article  PubMed  PubMed Central  CAS  Google Scholar 

Dranseikienė D, Balčiūnaitė-Murzienė G, Karosienė J, Morudov D, Juodžiukynienė N, Hudz N, Gerbutavičienė RJ, Savickienė N (2022) Cyano-phycocyanin: mechanisms of action on human skin and future perspectives in medicine. Plants (Basel) 11:1249. https://doi.org/10.3390/plants11091249

Article  PubMed  CAS  Google Scholar 

El-Aty AMA, Mohamed AA, Samhan FA (2014) In vitro antioxidant and antibacterial activities of two fresh water Cyanobacterial species, Oscillatoria agardhii and Anabaena sphaerica. J App Pharm Sci 4:69–75. https://doi.org/10.7324/JAPS.2014.40712

Article  Google Scholar 

Gammoudi S, Athmouni K, Nasri A, Diwani N, Grati I, Belhaj D, Bouaziz-Ketata H, Fki L, El Feki A, Ayadi H (2019) Optimization, isolation, characterization and hepatoprotective effect of a novel pigment-protein complex (phycocyanin) producing microalga: Phormidium versicolorNCC-466 using response surface methodology. Int J Biol Macromol 137:647–656. https://doi.org/10.1016/j.ijbiomac.2019.06.237

Article  PubMed  Google Scholar 

Gore E, Picard C, Savary G (2018) Spreading behavior of cosmetic emulsions: impact of the oil phase. Biotribology 16:17–24. https://doi.org/10.1016/j.biotri.2018.09.003

Article  Google Scholar 

Helfrich YR, Sachs DL, Voorhees JJ (2008) Overview of skin aging and photoaging. Dermatol Nurs 20:177–183; quiz 184

Hotos G (2021) Culture growth of the Cyanobacterium Phormidium sp. in various salinity and light regimes and their influence on its phycocyanin and other pigments content. J. mar. sci. eng 9:798. https://doi.org/10.3390/jmse9080798

Hsieh-Lo M, Castillo G, Ochoa-Becerra MA, Mojica L (2019) Phycocyanin and phycoerythrin: strategies to improve production yield and chemical stability. Algal Res 42:101600. https://doi.org/10.1016/j.algal.2019.101600

Article  Google Scholar 

Jusidin MR, Othman R, Shaleh SRM, Ching FF, Senoo S, Oslan SNH (2022) In vitro antibacterial activity of marine microalgae extract against Vibrio harveyi. Appl Sci 12:1148. https://doi.org/10.3390/app12031148

Article  CAS  Google Scholar 

Kamble SP, Gaikar RB, Padalia RB, Shinde KD (2013) Extraction and purification of C-phycocyanin from dry Spirulina powder and evaluating its antioxidant, anticoagulation and prevention of DNA damage activity. J Appl Pharm Sci 3:149–153. https://doi.org/10.7324/JAPS.2013.3826

Article  CAS  Google Scholar 

Kirby AJ, Schmidt RJ (1997) The antioxidant activity of Chinese herbs for eczema and of placebo herbs–I. J Ethnopharmacol 56:103–108. https://doi.org/10.1016/s0378-8741(97)01510-9

Article