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Eosinophilic Angiocentric Fibrosis: An Uncommon Entity in the Spectrum of IgG4-related Disease
Eosinophilic Angiocentric Fibrosis: An Uncommon Entity in the Spectrum of IgG4-related Disease
Eosinophilic angiocentric fibrosis (EAF) is a rare, tumefactive inflammatory process of the sinonasal and upper respirator...
Erdheim-Chester Disease of the Jaws: A Case Report and Review of the Literature
Erdheim-Chester Disease of the Jaws: A Case Report and Review of the Literature
Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytic disease characterized by xanthogranulomatous infil...
Branchioma: A Classic Example
Branchioma: A Classic Example
Branchioma is a very rare benign neoplasm of the neck. This case highlights its classic clinical presentation, histomorpho...
Etiopathogenesis of Oral Lichen Planus: A Review
Etiopathogenesis of Oral Lichen Planus: A Review
Oral lichen planus (OLP) is a chronic immune-mediated disease affecting the mucous membranes of the oral cavity, regarded ...
A Comprehensive Review of Kimura Disease
A Comprehensive Review of Kimura Disease
Kimura disease (KD) is a rare, chronic inflammatory disorder that primarily affects the head and neck regions, often mimic...
Rethinking Ameloblastic Fibroma and Fibro-odontoma: A Serie of 6 Cases and Reclassification Proposal
Rethinking Ameloblastic Fibroma and Fibro-odontoma: A Serie of 6 Cases and Reclassification Proposal
The classification of mixed odontogenic tumors—specifically ameloblastic fibroma (AF), ameloblastic fibro-odontoma (...
Blue Nevus of The Palate: A Case Image
Blue Nevus of The Palate: A Case Image
A 54-year-old female patient was referred to the oral surgery department of a public university with a complaint of a dark...
Lipomatous Metaplasia in a Warthin Tumor: A Rare Histopathological Finding
Lipomatous Metaplasia in a Warthin Tumor: A Rare Histopathological Finding
We present a case of Warthin tumor (WT) exhibiting lipomatous metaplasia. This rare histopathological feature can mimic li...
Revision of an Early History of Calcifying Epithelial Odontogenic Tumor: Herkert’s Original Description (1914)
Revision of an Early History of Calcifying Epithelial Odontogenic Tumor: Herkert’s Original Description (1914)
Polti LF, Gorrino-Baquero RB, Villegas KM, Amaya-Londoňo N, Paparella ML (2025) Calcifying epithelial odontogenic tumour (...
A Case of Acinic Cell Carcinoma Metastasizing to the Heart
A Case of Acinic Cell Carcinoma Metastasizing to the Heart
We present the case of a patient with acinic cell carcinoma of the parotid gland who was found to have metastasis to the l...
Human Dirofilariasis– An Underrecognized Zoonosis
Human Dirofilariasis– An Underrecognized Zoonosis
Dirofilariasis is a rare zoonotic disease caused by the filarial nematode of the genus Dirofilaria. It is an uncommon zoon...
Metastatic SMARCA4-Deficient Undifferentiated Carcinoma of the Oral Cavity: A Case Report and Review of Literature
Metastatic SMARCA4-Deficient Undifferentiated Carcinoma of the Oral Cavity: A Case Report and Review of Literature
SMARCA4-deficient high-grade malignancies are increasingly recognized across various anatomic sites, namely the genitourin...
Metastatic Intraparotid Balloon Cell Melanoma: A Diagnostic Challenge
Metastatic Intraparotid Balloon Cell Melanoma: A Diagnostic Challenge
BCM is an uncommon cytomorphologic variant with the potential to mimic unrelated neoplastic conditions, especially in the ...
Reticular and Myxoid Variant of EBV-positive Nasopharyngeal Carcinoma Mimicking Salivary Gland Tumors: A Case Series
Reticular and Myxoid Variant of EBV-positive Nasopharyngeal Carcinoma Mimicking Salivary Gland Tumors: A Case Series
This study aims to characterize the rare morphological variant of nasopharyngeal carcinoma known as reticular and myxoid n...
Unusual Locations of Extra-Glossal Ectomesenchymal Chondromyxoid Tumors with  Gene Fusions: A Report of Two Cases
Unusual Locations of Extra-Glossal Ectomesenchymal Chondromyxoid Tumors with Gene Fusions: A Report of Two Cases
Ectomesenchymal chondromyxoid tumor (EMCMT) is a rare benign tumor of the oral cavity that nearly always occurs in the ant...
Palisading Adenocarcinoma: Several New Inherited Cases in Six Patients of a Familial Cohort
Palisading Adenocarcinoma: Several New Inherited Cases in Six Patients of a Familial Cohort
The past two decades have seen the introduction of several new variants of established salivary gland tumors, along with o...
SMARCB1-Deficient Skull Base Chondrosarcoma with 12p Duplication Presenting as Somatic-Type Malignancy Arising from Metastatic Seminoma
SMARCB1-Deficient Skull Base Chondrosarcoma with 12p Duplication Presenting as Somatic-Type Malignancy Arising from Metastatic Seminoma
Somatic-type malignancy (STM) can occur infrequently within a primary or metastatic testicular germ cell tumor (TGCT) and ...
Traumatic Ulcerative Granuloma with Stromal Eosinophilia on the Tongue
Traumatic Ulcerative Granuloma with Stromal Eosinophilia on the Tongue
Traumatic Ulcerative Granuloma with Stromal Eosinophilia, commonly known as Eosinophilic Ulcer, is a reactive solitary and...
Top IHC/ISH Hacks for and Molecular Surrogates of Poorly Differentiated Sinonasal Small Round Cell Tumors
Top IHC/ISH Hacks for and Molecular Surrogates of Poorly Differentiated Sinonasal Small Round Cell Tumors
Poorly differentiated sinonasal small round cell tumors (SRCTs) are rare and heterogeneous, posing challenges in diagnosis...
Fungal Otitis Externa (Otomycosis) Associated with Aspergillus Flavus: A Case Image
Fungal Otitis Externa (Otomycosis) Associated with Aspergillus Flavus: A Case Image
A 48-year-old man presented with a chief complaint of intermittent right ear otorrhea of several-month duration, occasiona...
Odontoameloblastoma: A Distinct Entity?
Odontoameloblastoma: A Distinct Entity?
Kramer IR, Pindborg JJ, Shear M (1992) World Health Organization international histologic classification of tumours. Histo...
Spindle Cell Tumors of the Sinonasal Tract: A Diagnostic Update with Focus on Ancillary Workup
Spindle Cell Tumors of the Sinonasal Tract: A Diagnostic Update with Focus on Ancillary Workup
Spindle cell neoplasms arising in the head and neck may be challenging to recognize due to their relative rarity. While un...
Pleomorphic Adenoma with a Novel Gene Rearrangement—LINC01606::PLAG1
Pleomorphic Adenoma with a Novel Gene Rearrangement—LINC01606::PLAG1
Pleomorphic adenoma is a well-known benign salivary gland neoplasm characterized by the presence of varying proportions of...
Primary Oral Mixed Neuroendocrine–Non-neuroendocrine Neoplasm (MiNEN): A Rare Case Report and Review of the Literature
Primary Oral Mixed Neuroendocrine–Non-neuroendocrine Neoplasm (MiNEN): A Rare Case Report and Review of the Literature
Mixed neuroendocrine–non-neuroendocrine neoplasms (MiNENs) are rare tumors recently characterized by the presence of...
Dynamic Role of miRNAs in Salivary Gland Carcinomas: From Biomarkers to Therapeutic Targets
Dynamic Role of miRNAs in Salivary Gland Carcinomas: From Biomarkers to Therapeutic Targets
Salivary gland carcinomas (SGCs) are a rare group of malignant neoplasms of the head and neck region. MicroRNAs (miRNAs) a...