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Evolving trends and clinical-pathological correlations in renal cell carcinoma surgery: a decade-long study at Peking University First Hospital
Evolving trends and clinical-pathological correlations in renal cell carcinoma surgery: a decade-long study at Peking University First Hospital
This study aimed to comprehensively delineate the clinical characteristics, surgical interventions, and evolving trends ov...
From cardiac injury to omics signatures: a narrative review on biomarkers in septic cardiomyopathy
From cardiac injury to omics signatures: a narrative review on biomarkers in septic cardiomyopathy
Septic cardiomyopathy (SCM) is a frequent and underdiagnosed complication of sepsis that contributes significantly to pati...
The association between 4-HPR-mediated LCN2 suppression and reduced intestinal cell senescence in ulcerative colitis
The association between 4-HPR-mediated LCN2 suppression and reduced intestinal cell senescence in ulcerative colitis
Ulcerative colitis is a type of inflammatory bowel disease that can significantly impact patients’ life, leading to ...
Efficacy of combination chelation with deferasirox and deferiprone in children with beta-thalassemia major: an audit from a unit in the developing world
Efficacy of combination chelation with deferasirox and deferiprone in children with beta-thalassemia major: an audit from a unit in the developing world
Effective iron chelation is crucial for preventing morbidity and mortality in transfusion-dependent beta-thalassemia major...
Prevalence and outcome of VEXAS syndrome in unrelated hematopoietic cell transplantation for bone marrow failure
Prevalence and outcome of VEXAS syndrome in unrelated hematopoietic cell transplantation for bone marrow failure
VEXAS syndrome (vacuoles, E1 enzyme, X-linked, autoinflammatory, and somatic) is a recently identified clonal disorder cau...
Therapeutic options for extramedullary involvement in multiple myeloma
Therapeutic options for extramedullary involvement in multiple myeloma
Extramedullary involvement (extramedullary disease, EMD) is an aggressive subtype of multiple myeloma (MM) characterized b...
Diagnostic utility and clinical relevance of anti-MCV and anti-CCP antibodies in rheumatoid arthritis
Diagnostic utility and clinical relevance of anti-MCV and anti-CCP antibodies in rheumatoid arthritis
Rheumatoid arthritis (RA) is a persistent autoimmune disorder where serological biomarkers play a crucial role in diagnosi...
SLFN11, far from being limited to responding to cancer DNA damage
SLFN11, far from being limited to responding to cancer DNA damage
SLFN11, a member of the evolutionarily conserved SLFN gene family, is an interferon-stimulated early response gene. This r...
Impact of exercise on immune cell infiltration in muscle tissue: implications for muscle repair and chronic disease
Impact of exercise on immune cell infiltration in muscle tissue: implications for muscle repair and chronic disease
Exercise has long been recognized for its systemic health benefits, including modulation of the immune system. Contemporar...
The shared genetic etiology of autoimmune disorders and interstitial lung disease: insights from large-scale genome-wide cross-trait analysis
The shared genetic etiology of autoimmune disorders and interstitial lung disease: insights from large-scale genome-wide cross-trait analysis
Autoimmune diseases often co-occur with interstitial lung disease (ILD), and ILD is associated with patient prognosis. Res...
Elevated expression of transferrin receptor-1 in pancreatic cancer: clinical implications and prognostic significance
Elevated expression of transferrin receptor-1 in pancreatic cancer: clinical implications and prognostic significance
Many advanced-stage pancreatic cancers are fatal, highlighting the need for solid prognostic indicators. This study evalua...
The dual burden of tuberculosis and diabetes mellitus: an epidemiological correlation
The dual burden of tuberculosis and diabetes mellitus: an epidemiological correlation
This study examined the association between diabetes mellitus and tuberculosis (TB) in a cohort of 200TB-positive patients...
Integrating multi-omics approaches in acute myeloid leukemia (AML): Advancements and clinical implications
Integrating multi-omics approaches in acute myeloid leukemia (AML): Advancements and clinical implications
Acute myeloid leukemia (AML) is a highly heterogeneous and aggressive hematologic malignancy characterized by clonal proli...
Comprehensive analysis of KRT18 as a novel prognostic biomarker and potential target in lung adenocarcinoma
Comprehensive analysis of KRT18 as a novel prognostic biomarker and potential target in lung adenocarcinoma
Background: The expression characteristics of Keratin 18 (KRT18) in lung adenocarcinoma (LUAD) remain incompletely elucida...
Implementation effects of quality control circle in improving medication adherence of outpatient helicobacter pylori patients
Implementation effects of quality control circle in improving medication adherence of outpatient helicobacter pylori patients
To evaluate the implementation effects of problem-solving Quality Control Circle (QCC) activities on medication adherence ...
Prevalence of sacroiliitis on magnetic resonance enterography in Crohn’s disease and its association with intestinal findings: a monocentric observational cross-sectional study
Prevalence of sacroiliitis on magnetic resonance enterography in Crohn’s disease and its association with intestinal findings: a monocentric observational cross-sectional study
Magnetic resonance enterography (MRE) is recommended for the assessment of small intestine alterations in Crohn’s di...
YY1-mediated DUXAP8 facilitates HCC progression via modulating DEPDC1 expression
YY1-mediated DUXAP8 facilitates HCC progression via modulating DEPDC1 expression
The long noncoding RNA DUXAP8 has been implicated in the progression of various malignancies, including hepatocellular car...
Activation of RHO-GTPase gene pattern correlates with adverse clinical outcome and immune microenvironment in clear cell renal cell carcinoma
Activation of RHO-GTPase gene pattern correlates with adverse clinical outcome and immune microenvironment in clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC), the most prevalent renal cancer subtype, is frequently associated with poor progn...
Prediction of vedolizumab efficacy in ulcerative colitis: a nomogram incorporating pathological feature and serological marker
Prediction of vedolizumab efficacy in ulcerative colitis: a nomogram incorporating pathological feature and serological marker
Vedolizumab (VDZ) is a humanized, gut-selective biologic used in the treatment of ulcerative colitis (UC). However, data o...
The value of plasma sCD25 in diagnosis, therapeutic efficacy, and prognosis of acute myeloid leukemia
The value of plasma sCD25 in diagnosis, therapeutic efficacy, and prognosis of acute myeloid leukemia
This study aims to investigate the clinical importance of soluble CD25 (sCD25) levels in diagnosing acute myeloid leukemia...
Efficacy and safety analysis of atezolizumab continuation beyond progression in extensive-stage small cell lung cancer
Efficacy and safety analysis of atezolizumab continuation beyond progression in extensive-stage small cell lung cancer
The advent of immune checkpoint inhibitors (ICIs) has revolutionized the treatment landscape for extensive-stage small cel...
The relationship between telomere length and aging-related diseases
The relationship between telomere length and aging-related diseases
The intensifying global phenomenon of an aging population has spurred a heightened emphasis on studies on aging and disord...
Macrophages in graft-versus-host disease (GVHD): dual roles as therapeutic tools and targets
Macrophages in graft-versus-host disease (GVHD): dual roles as therapeutic tools and targets
Graft-versus-host disease remains one of the most formidable barriers to the complete success of hematopoietic stem cell t...
Periostin and rheumatic diseases: early insights from a systematic review and meta-analysis
Periostin and rheumatic diseases: early insights from a systematic review and meta-analysis
Periostin regulates angiogenesis, inflammation, and fibrosis, key processes in the pathophysiology of rheumatic diseases (...
The double-edged sword of lncRNAs in rheumatoid arthritis: from controlling the disease to its progress
The double-edged sword of lncRNAs in rheumatoid arthritis: from controlling the disease to its progress
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by chronic inflammatory responses in the joints, s...
Antiphospholipid syndrome in patients with fetal death: a prospective longitudinal cohort study
Antiphospholipid syndrome in patients with fetal death: a prospective longitudinal cohort study
To investigate the causes of fetal death, focusing on maternal antiphospholipid syndrome diagnosis, and to follow the pati...
High-altitude pulmonary hypertension: a comprehensive review of mechanisms and management
High-altitude pulmonary hypertension: a comprehensive review of mechanisms and management
High-altitude pulmonary hypertension (HAPH) is characterized by an increase in pulmonary artery pressure due to prolonged ...
VEGF-A in COVID-19: a systematic review and meta-analytical approach to its prognostic value
VEGF-A in COVID-19: a systematic review and meta-analytical approach to its prognostic value
Numerous studies have reported vascular endothelial growth factor A (VEGF-A) has a significant impact on...
CD44v6-mediated regulation of gastric cancer stem cells: a potential therapeutic target
CD44v6-mediated regulation of gastric cancer stem cells: a potential therapeutic target
Gastric cancer is the fourth most common cause of cancer-related deaths globally. Cancer stem cells (CSCs) play an essenti...
Predicting sentinel lymph node metastasis in breast cancer: a study based on the SEER database
Predicting sentinel lymph node metastasis in breast cancer: a study based on the SEER database
Sentinel lymph node biopsy (SLNB), a standard surgical procedure for clinically axillary-negative breast cancer patients, ...
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