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YY1-mediated DUXAP8 facilitates HCC progression via modulating DEPDC1 expression
YY1-mediated DUXAP8 facilitates HCC progression via modulating DEPDC1 expression
The long noncoding RNA DUXAP8 has been implicated in the progression of various malignancies, including hepatocellular car...
Activation of RHO-GTPase gene pattern correlates with adverse clinical outcome and immune microenvironment in clear cell renal cell carcinoma
Activation of RHO-GTPase gene pattern correlates with adverse clinical outcome and immune microenvironment in clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC), the most prevalent renal cancer subtype, is frequently associated with poor progn...
Prediction of vedolizumab efficacy in ulcerative colitis: a nomogram incorporating pathological feature and serological marker
Prediction of vedolizumab efficacy in ulcerative colitis: a nomogram incorporating pathological feature and serological marker
Vedolizumab (VDZ) is a humanized, gut-selective biologic used in the treatment of ulcerative colitis (UC). However, data o...
The value of plasma sCD25 in diagnosis, therapeutic efficacy, and prognosis of acute myeloid leukemia
The value of plasma sCD25 in diagnosis, therapeutic efficacy, and prognosis of acute myeloid leukemia
This study aims to investigate the clinical importance of soluble CD25 (sCD25) levels in diagnosing acute myeloid leukemia...
Efficacy and safety analysis of atezolizumab continuation beyond progression in extensive-stage small cell lung cancer
Efficacy and safety analysis of atezolizumab continuation beyond progression in extensive-stage small cell lung cancer
The advent of immune checkpoint inhibitors (ICIs) has revolutionized the treatment landscape for extensive-stage small cel...
The relationship between telomere length and aging-related diseases
The relationship between telomere length and aging-related diseases
The intensifying global phenomenon of an aging population has spurred a heightened emphasis on studies on aging and disord...
Macrophages in graft-versus-host disease (GVHD): dual roles as therapeutic tools and targets
Macrophages in graft-versus-host disease (GVHD): dual roles as therapeutic tools and targets
Graft-versus-host disease remains one of the most formidable barriers to the complete success of hematopoietic stem cell t...
Periostin and rheumatic diseases: early insights from a systematic review and meta-analysis
Periostin and rheumatic diseases: early insights from a systematic review and meta-analysis
Periostin regulates angiogenesis, inflammation, and fibrosis, key processes in the pathophysiology of rheumatic diseases (...
The double-edged sword of lncRNAs in rheumatoid arthritis: from controlling the disease to its progress
The double-edged sword of lncRNAs in rheumatoid arthritis: from controlling the disease to its progress
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by chronic inflammatory responses in the joints, s...
Antiphospholipid syndrome in patients with fetal death: a prospective longitudinal cohort study
Antiphospholipid syndrome in patients with fetal death: a prospective longitudinal cohort study
To investigate the causes of fetal death, focusing on maternal antiphospholipid syndrome diagnosis, and to follow the pati...
High-altitude pulmonary hypertension: a comprehensive review of mechanisms and management
High-altitude pulmonary hypertension: a comprehensive review of mechanisms and management
High-altitude pulmonary hypertension (HAPH) is characterized by an increase in pulmonary artery pressure due to prolonged ...
VEGF-A in COVID-19: a systematic review and meta-analytical approach to its prognostic value
VEGF-A in COVID-19: a systematic review and meta-analytical approach to its prognostic value
Numerous studies have reported vascular endothelial growth factor A (VEGF-A) has a significant impact on...
CD44v6-mediated regulation of gastric cancer stem cells: a potential therapeutic target
CD44v6-mediated regulation of gastric cancer stem cells: a potential therapeutic target
Gastric cancer is the fourth most common cause of cancer-related deaths globally. Cancer stem cells (CSCs) play an essenti...
Predicting sentinel lymph node metastasis in breast cancer: a study based on the SEER database
Predicting sentinel lymph node metastasis in breast cancer: a study based on the SEER database
Sentinel lymph node biopsy (SLNB), a standard surgical procedure for clinically axillary-negative breast cancer patients, ...
Circulating tumor DNA methylation markers for the early diagnosis of hepatocellular carcinoma
Circulating tumor DNA methylation markers for the early diagnosis of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a major global health concern, being the sixth most common cancer and the third leading ...
Correction to: Evaluation of Bruton tyrosine kinase inhibitors monotherapy and combination therapy in lymphocytic leukemia
Correction to: Evaluation of Bruton tyrosine kinase inhibitors monotherapy and combination therapy in lymphocytic leukemia
Correction to: Clinical and Experimental Medicine https://doi.org/10.1007/s10...
Correction to: Reduced regulatory effects of bone marrow-derived mesenchymal stem cells on activated T lymphocytes and Th1/Th2 cytokine secretion in children with aplastic anemia
Correction to: Reduced regulatory effects of bone marrow-derived mesenchymal stem cells on activated T lymphocytes and Th1/Th2 cytokine secretion in children with aplastic anemia
The article Reduced regulatory effects of bone marrow‑derived mesenchymal stem cells on activated T lymphocytes and Th1/Th...
Correction to: Diagnosis of interstitial lung disease (ILD) secondary to systemic sclerosis (SSc) and rheumatoid arthritis (RA) and identification of ‘progressive pulmonary fibrosis’ using chest CT: a narrative review
Correction to: Diagnosis of interstitial lung disease (ILD) secondary to systemic sclerosis (SSc) and rheumatoid arthritis (RA) and identification of ‘progressive pulmonary fibrosis’ using chest CT: a narrative review
In the original version of this article, two author names were missing. The missi...
EMT-induced immune evasion: connecting the dots from mechanisms to therapy
EMT-induced immune evasion: connecting the dots from mechanisms to therapy
Epithelial–mesenchymal transition (EMT) is a dynamic program crucial for organismal development and tissue regenerat...
Vaccine effectiveness of COVID-19 and rebound in the real world
Vaccine effectiveness of COVID-19 and rebound in the real world
We intend to evaluate the relationship between the rates of global SARS-CoV-2 vaccination and the number of COVID-19 confi...
Clinical and imaging features of lymphomatosis cerebri: analysis of 8 cases and systematic review of the literature
Clinical and imaging features of lymphomatosis cerebri: analysis of 8 cases and systematic review of the literature
Lymphomatosis cerebri (LC) is a rare type of primary central nervous system lymphoma with diffuse, nonenhancing infiltrati...
Real-life diagnostic and therapeutic approach to CLL: a 2022 update from an expert panel in Tuscany
Real-life diagnostic and therapeutic approach to CLL: a 2022 update from an expert panel in Tuscany
A panel of chronic lymphocytic leukemia (CLL) experts from Tuscany propose a real-life diagnostic and therapeutic approach...
Pan-PI3K inhibition with copanlisib overcomes Treg- and M2-TAM-mediated immune suppression and promotes anti-tumor immune responses
Pan-PI3K inhibition with copanlisib overcomes Treg- and M2-TAM-mediated immune suppression and promotes anti-tumor immune responses
The PI3K pathway is one of the most frequently altered signaling pathways in human cancer. In addition to its function in ...
Immune profile alterations of systemic lupus erythematosus patients with infections
Immune profile alterations of systemic lupus erythematosus patients with infections
This study aimed to elucidate the immune status of systemic lupus erythematosus (SLE) patients with infections. We enrolle...
Treatment outcomes of patients with classic and AIDS-related Kaposi Sarcoma: a single-center real-world experience
Treatment outcomes of patients with classic and AIDS-related Kaposi Sarcoma: a single-center real-world experience
The recommended first-line chemotherapy agents for managing Kaposi sarcoma (KS) in high-income countries are expensive and...
Bone targeting agents, but not radiation therapy, improves survival in patients with bone metastases from advanced urothelial carcinoma receiving pembrolizumab: results from the ARON-2 study
Bone targeting agents, but not radiation therapy, improves survival in patients with bone metastases from advanced urothelial carcinoma receiving pembrolizumab: results from the ARON-2 study
The ARON-2 study (NCT05290038) aimed to assess the real-world efficacy of pembrolizumab in patients recurred or progressed...
Clonally related transformation from Waldenström macroglobulinemia to diffuse large B-cell lymphoma with central nervous system involvement at diagnosis: a case report and literature review
Clonally related transformation from Waldenström macroglobulinemia to diffuse large B-cell lymphoma with central nervous system involvement at diagnosis: a case report and literature review
Histological transformation to diffuse large B-cell lymphoma (DLBCL) rarely occurs in patients with Waldenström macro...
MicroRNA as a potential biomarker for systemic lupus erythematosus: pathogenesis and targeted therapy
MicroRNA as a potential biomarker for systemic lupus erythematosus: pathogenesis and targeted therapy
Systemic lupus erythematosus (SLE) is an autoimmune disease associated with hyperactive innate and adaptive immune systems...
Efficacy and safety of Orelabrutinib-based regimens in diffuse large B-cell lymphoma: a single-center retrospective analysis
Efficacy and safety of Orelabrutinib-based regimens in diffuse large B-cell lymphoma: a single-center retrospective analysis
Currently, combining chemotherapy with Bruton tyrosine kinase inhibitors (BTKi) has demonstrated significant effectiveness...
A systematic review regarding the prevalence of malignancy in patients with the hyper-IgE syndrome
A systematic review regarding the prevalence of malignancy in patients with the hyper-IgE syndrome
The hyper-immunoglobulin E syndrome (HIES) is a primary immunodeficiency disease originally described as Job syndrome. The...
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